Immature ovarian teratoma in a 20-year-old woman: A case report
This article reviews the clinical presentation, imaging features, and some of the main problems that arise in the management of immature ovarian teratomas.PMID:38410854 | DOI:10.1177/03000605241232568 (Source: Cell Research)
Source: Cell Research - February 27, 2024 Category: Cytology Authors: L Errami A Douzi O Lamzouri H Taheri H Saadi A Mimouni Source Type: research
Outcome of patients with stage I immature teratoma after surveillance or adjuvant chemotherapy
ConclusionsOur results support the feasibility of surveillance in stage I immature teratomas. Adjuvant chemotherapy may be reserved for relapses. However, the potential benefit of chemotherapy should be discussed, especially for high-risk tumours. Prospective series are warranted to confirm our findings.What is already known on this topicTo date, no consensus has been reached regarding the role of adjuvant chemotherapy in stage I immature teratomas of the ovary. Some studies suggest that only surveillance is an acceptable choice. However, guidelines are not conclusive on this topic.What this study addsNo difference in term...
Source: Frontiers in Oncology - February 2, 2024 Category: Cancer & Oncology Source Type: research
Immature Teratoma of Ethmoid Sinus Masquerading as Antrochoanal Polyp: A Rare Case Report with Literature Review
AbstractTeratomas are rare neoplasms that arise from totipotent stem cells. Teratomas of the head and neck are extremely rare, constituting about 10% of all cases and usually present in the neonatal period. Extensive literature search has shown that there are only two cases reportedof teratoma of the ethmoid sinus; one as a mature teratoma in a neonate and another was histologically immature teratoma in an adult male (Mwang ’ombe et al. in East Afr Med J 79(2):106–107, 2002; Aggarwal et al. in J Postgrad Med 59(2):138–141, 2013). We hereby report the second case of immature teratoma of ethmoid sinus origin in an adul...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - December 12, 2023 Category: ENT & OMF Source Type: research
The Irish Experience with Sacrococcygeal Teratomas: Are Type IV Lesions More Common than We Think?
Conclusion In Altman's original 1974 study, type IV lesions were present in 10% of cases. As a result, this is the most frequently quoted figure. Type IV lesions were present in 28% of cases in our study. We propose that type IV lesions may be more common than the current literature suggests and consequently a higher index of suspicion of their presence should be entertained. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - November 28, 2023 Category: Surgery Authors: Kane, Gavin Alan Mortell, Alan Gillick, John Thambipillai, Sri Paran Cascio, Salvatore Tags: Original Article Source Type: research
Giant sacrococcygeal teratoma in an infant: a case report with a literature review
CONCLUSION: SCT has rarely been reported as a giant mass. Radiologic examinations in the early stages of pregnancy may be essential to the early diagnosis of the condition.PMID:37915688 | PMC:PMC10617840 | DOI:10.1097/MS9.0000000000001274 (Source: Annals of Medicine)
Source: Annals of Medicine - November 2, 2023 Category: Internal Medicine Authors: Wirya N Sabir Sasan M Ahmed Karzan M Hasan Bilal A Mohammed Honar Othman Kareem Zana B Najmadden Berun A Abdalla Rawezh Q Salih Shvan H Mohammed Fahmi H Kakamad Hevar A Azaldeen Source Type: research
Primary Immature Renal Teratoma in a Neonate
Oman Med J. 2023 Sep 28;38(5):e558. doi: 10.5001/omj.2023.49. eCollection 2023 Sep.ABSTRACTTeratomas are neoplasms that commonly arise from the gonads. It is rare that they originate in the kidney. Immature intrarenal teratomas are exceptionally rare. To our knowledge, the current case will be the fifth immature intrarenal teratoma reported in the literature, in addition to being the first such case reported in a neonate.PMID:37771890 | PMC:PMC10522884 | DOI:10.5001/omj.2023.49 (Source: Oman Medical Journal)
Source: Oman Medical Journal - September 29, 2023 Category: Middle East Health Authors: Ali Al Sharqi Sareyah Mouaffak Fathiya Al Rahbi Saleh Bawain Noor Fatema Najwa Al-Rahbi Zainab Al Balushi Source Type: research
IJERPH, Vol. 20, Pages 6089: Clinical Challenges in the Management of Malignant Ovarian Germ Cell Tumours
gios Boussios
Nonepithelial ovarian cancers (NEOC) are a group of rare malignancies, including germ cell tumours (GCT) and sex cord-stromal tumours (SCST), along with small-cell carcinomas and sarcomas. GCTs represent 2–5% of ovarian cancers, with a yearly incidence of 4:100,000, and they usually affect young women and adolescents. Precursory germ cells of the ovary form the basis of GCT. They are histologically classified into primitive GCT, teratomas, and monodermal and somatic-type tumours associated with dermoid cysts. A primitive GCT can be either a yolk sac tumour (YST), dysgerminoma, or mixed germ ...
Source: International Journal of Environmental Research and Public Health - June 9, 2023 Category: Environmental Health Authors: Iqra Saani Nitish Raj Raja Sood Shahbaz Ansari Haider Abbas Mandviwala Elisabet Sanchez Stergios Boussios Tags: Review Source Type: research
Mnangement of an immature dermoid ovarian cyst
Introduction: Ovarian tumors are a frequent pathology in women; they are characterized by their clinical, radiological and anatomopathologic polymorphism. Among the germinal tumors of the ovary, the mature teratomas are the most found with a frequency of 10 to 20%. Their malignant transformation is a very rare entity of the order of 2% and is generally seen in peri and in post-menopause. Degeneration occurs in 80% of cases into squamous cell carcinoma; however, other rarer histological forms are described. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Salma Bouguerra, Syrine Ben Saidane Tags: Abstract ID: 215 Source Type: research
Characterization of immature ovarian teratomas through single-cell transcriptome
This study provides a comprehensive profile of PDT at the single cell level, shedding light on the heterogeneity and evolution of neuroectodermal cells within PDTs and the role of immune cells within the tumor microenvironment. Also, our findings highlight the potential usage of CDTs as a model for research on PDT. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 3, 2023 Category: Allergy & Immunology Source Type: research
Clinical characteristics and long-term management of prepubertal testicular teratomas: a retrospective, multicenter study
Conclusion: Testicular-sparing surgery is the first treatment choice for prepubertal testicular teratomas, with the scrotal approach being a safe and well-tolerated strategy for these diseases. Additionally, patients with immature teratomas and cryptorchidism may have tumor recurrence or metastasis after surgery. Therefore, these patients should be closely followed up in the first year after surgery.What is Known:• There is a fundamental difference between testicular tumours in childhood and those in adulthood - not only in terms of the difference and incidence but also in terms of histology.• For surgical techniques, ...
Source: European Journal of Pediatrics - February 16, 2023 Category: Pediatrics Source Type: research
Mature and immature ovarian teratomas share methylation profiles of imprinted genes: a MS-MLPA analysis
AbstractImmature teratomas are a subset of ovarian teratomas, and the pathogenic relationship between mature and immature ovarian teratomas is unclear. Mature ovarian teratomas are parthenogenetic tumors that arise from a single oocyte/ovum, whereas the origin of immature ovarian teratomas has not been extensively investigated. Since parthenogenetic tumors contain only maternal genomes, genome imprinting in these tumors usually follows a maternal pattern. DNA methylation is among the most important mechanisms of genome imprinting. Therefore, we analyzed the methylation profile of imprinted genes by performing methylation-s...
Source: Virchows Archiv - January 13, 2023 Category: Pathology Source Type: research
Genomic characterization of intracranial teratomas using whole genome sequencing
ConclusionsOur study revealed the genetic characteristics of intracranial teratoma which might be valuable for guiding future targeted therapies. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - November 15, 2022 Category: Cancer & Oncology Source Type: research
