Teratoma of the Sellar Region: a Case Report
AbstractThe case report describes a teratoma of the sellar region with a gland forming and an immature, relatively clear undifferentiated component without signs of anaplasia. Both components express TTF-1 indicating their presumable origin in the neurohypophysis as part of the circumventricular organs. The differential diagnosis includes pituitary adenoma and spindle cell oncocytoma with inclusion of Rathke ’s cleft cyst, pituitary blastoma, yolk sac tumor, and other germ cell tumors. The prognosis is the same as in the immature teratomas in the gonads, specifically unclear. (Source: Endocrine Pathology)
Source: Endocrine Pathology - January 18, 2017 Category: Pathology Source Type: research

Teratomas of the cranial vault: a systematic analysis of clinical outcomes stratified by histopathological subtypes
ConclusionsOur data highlight the divergent nature of the different histopathological subtypes of teratomas, and suggest that survival outcomes are multifactorial. Specifically, male sex, pineal, suprasellar, GTR, and STR were dependent predictors of OS, while histopathology was an independent predictor of OS. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - January 13, 2017 Category: Neurosurgery Source Type: research

Ovarian tumors in children: 10-year experience from a tertiary care center in South India
Conclusion: Germ cell tumors are the most common ovarian malignancy in children. With surgery and chemotherapy using BEP, good outcome can be expected in these patients. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - January 5, 2017 Category: Cancer & Oncology Authors: B Rajeswari M Nair A Ninan K Parukuttyamma Source Type: research

The role of staging and adjuvant chemotherapy in stage I malignant ovarian germ cell tumors (MOGTs): the MITO-9 study
Conclusions</div>This study shows that surveillance seems not to affect survival; chemotherapy should be reserved for relapse resulting in high cure rate. Incomplete peritoneal surgical staging is associated with recurrence. Yolk sac histology worsens the prognosis.</span> (Source: Annals of Oncology)
Source: Annals of Oncology - October 31, 2016 Category: Cancer & Oncology Source Type: research

Gliomatosis peritonei with bilateral ovarian teratomas: A report of two cases.
Authors: Wang J, Xu J, Zhang M, Li B Abstract Gliomatosis peritonei (GP) is characterized by the presence of benign, mature neuroglial implants throughout the peritoneum and is typically accompanied by mature or immature ovarian teratomas. GP is a condition that has only been described relatively recently, with ~100 cases reported in the English literature. The majority of reported cases have focused on the pathology and clinical treatment of the disease; radiological findings are distinct, but the discussion of this is scarce in the literature. The current study presents two cases of GP with bilateral ova...
Source: Oncology Letters - September 8, 2016 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research

OC10.06: Imaging in gynecological disease: clinical and ultrasound features of immature teratomas of the ovary
(Source: Ultrasound in Obstetrics and Gynecology)
Source: Ultrasound in Obstetrics and Gynecology - September 7, 2016 Category: Radiology Authors: C. Landolfo, W. Froyman, A.C. Testa, A. Czekierdowski, S. Guerriero, A. Coosemans, D. Franchi, C. Van Holsbeke, B. Van Calster, J. Verbakel, E. Van Nieuwenhuysen, I. Vergote, D. Timmerman, L. Valentin Tags: Abstracts Source Type: research

Evidence of a dual histogenetic pathway of sacrococcygeal teratomas
ConclusionsOur data suggest that pediatric sacrococcygeal teratomas should be considered as two distinct groups with a divergent histogenetic pathway. Prognosis of these tumors is excellent, despite rare recurrence.This article is protected by copyright. All rights reserved. (Source: Histopathology)
Source: Histopathology - August 14, 2016 Category: Pathology Authors: Robert E. Emerson, Chia ‐Sui Kao, John N. Eble, David J. Grignon, Mingsheng Wang, Shaobo Zhang, Xiaoyan Wang, Rong Fan, Timothy A. Masterson, Lawrence M. Roth, Liang Cheng Tags: Original Article Source Type: research

Ovarian masses with papillary projections diagnosed and removed during pregnancy: ultrasound features and histological diagnoses.
CONCLUSIONS: During pregnancy cysts with papillations with smooth contour and ground glass echogenicity of cyst fluid on ultrasound are most likely to be decidualized endometriomas. Papillations with irregular contour and anechoic or low level echogenicity of cyst fluid suggest borderline malignancy. PMID: 27484484 [PubMed - as supplied by publisher] (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - August 2, 2016 Category: Radiology Authors: Mascilini F, Savelli L, Scifo MC, Exacoustos C, Timor-Tritsch I, De Blasis I, Moruzzi MC, Pasciuto T, Scambia G, Valentin L, Testa AC Tags: Ultrasound Obstet Gynecol Source Type: research

Ovarian masses with papillary projections diagnosed and removed during pregnancy: ultrasound features and histological diagnoses
CONCLUSIONSDuring pregnancy cysts with papillations with smooth contour and ground glass echogenicity of cyst fluid on ultrasound are most likely to be decidualized endometriomas. Papillations with irregular contour and anechoic or low level echogenicity of cyst fluid suggest borderline malignancy. (Source: Ultrasound in Obstetrics and Gynecology)
Source: Ultrasound in Obstetrics and Gynecology - August 2, 2016 Category: Radiology Authors: F. Mascilini, L. Savelli, M.C. Scifo, C. Exacoustos, I. Timor ‐Tritsch, I. De Blasis, M.C. Moruzzi, T. Pasciuto, G. Scambia, L. Valentin, A.C. Testa Tags: Original Paper Source Type: research

Recent advances in molecular biology and treatment strategies for intracranial germ cell tumors.
CONCLUSIONS: IGCTs should be strictly classified according to their pathological categories before administering pathology-specific treatments. Although open microsurgical excision is the traditional surgical strategy for IGCTs, recent publications also support the role of endoscopic surgical options for pineal region IGCTs. PMID: 27351562 [PubMed - as supplied by publisher] (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - June 30, 2016 Category: Pediatrics Authors: Huang X, Zhang R, Mao Y, Zhou LF, Zhang C Tags: World J Pediatr Source Type: research

Racial disparities in presentation and survival of ovarian yolk sac cancer patients: a study of 423 women
Ovarian germ cell cancers comprise 3-5% of all ovarian malignancies. Patients with yolk sac tumors have a worse prognosis compared to those with dysgerminomas or immature teratomas.1,2 Due to the rarity of yolk sac tumors, few studies have evaluated their distinct demographic and clinicopathologic features. Previous studies have demonstrated that Asians and blacks have an increased incidence of germ cell cancers.3,4 We propose to determine the factors associated with the presentation and survival rates of ovarian yolk sac cancer patients. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 4, 2016 Category: OBGYN Authors: John K. Chan, Austin B. Gardner, Cheng-I Liao, Joshua Chan, Andrew Guan, Mark Alshak, Daniel S. Kapp Tags: Letter to the Editor Source Type: research

Racial disparities in presentation and survival of  ovarian yolk sac cancer patients: a study of 423 women
Ovarian germ cell cancers comprise 3-5% of all ovarian malignancies. Patients with yolk sac tumors have a worse prognosis compared to those with dysgerminomas or immature teratomas.1,2 Due to the rarity of yolk sac tumors, few studies have evaluated their distinct demographic and clinicopathologic features. Previous studies have demonstrated that Asians and blacks have an increased incidence of germ cell cancers.3,4 We propose to determine the factors associated with the presentation and survival rates of ovarian yolk sac cancer patients. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 4, 2016 Category: OBGYN Authors: John K. Chan, Austin B. Gardner, Cheng-I Liao, Joshua Chan, Andrew Guan, Mark Alshak, Daniel S. Kapp Tags: Letter to the Editor Source Type: research

Immature teratoma of the tectum mesencephali with histopathological detection of rudimentary eye anlage in a 3‐year‐old boy: Report of a rare case
Intracranial teratoma is a rare neoplasm derived from omnipotent germinal cells that can contain mesoderm, endoderm and/or ectoderm layer tissue. Histologically teratomas are characterized by abnormal structures like teeth or bone that can be further subdivided into mature and immature according to the presence of incompletely differentiated tissue. Characteristic intracranial teratomas are space‐occupying lesions in the pineal region and often present with hydrocephalic symptoms due to aqueduct stenosis. A 3‐year‐old boy presented with a peracute hemiparesis, fatigue and speech deficit. MRI diagnostics showed a cyst...
Source: Neuropathology - March 31, 2016 Category: Neurology Authors: Daniel Dubinski, Michel Mittelbronn, Gerhard Marquardt, Dominique S. Tews, Anika Noack, Bedjan Behmanesh, Volker Seifert, Thomas M. Freiman Tags: Case Report Source Type: research

Huge congenital cervical immature teratoma mimicking lymphatic malformation in a 7-day-old male neonate
This report describes a 7-day-old male neonate who presented at our institution with a huge neck mass that was treated by surgical excision. (Source: Journal of Pediatric Surgery Case Reports)
Source: Journal of Pediatric Surgery Case Reports - March 20, 2016 Category: Surgery Source Type: research