News from the world of oncology
Indian Journal of Cancer 2019 56(3):287-289 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Source Type: research

The spread of radiology in India from 1941 to 1956
Robert D SmithIndian Journal of Cancer 2019 56(3):285-286 This commentary discusses how the reasoning behind the founding of Tata Memorial Hospital (TMH), India's first specialized cancer hospital, was influential in setting up a larger infrastructure of cancer care in India. I show how the arguments that led to the use of radium at TMH enabled the value that TMH placed upon radiology to permeate other institutions around India, ultimately establishing radium as an essential element of cancer care. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Robert D Smith Source Type: research

The founding of the Tata Memorial Hospital, 1932-1941
This article presents a brief account of the founding of the Tata Memorial Hospital. It draws upon archival material to show that this was not a mere philanthropic act but a scheme carefully thought-out by the Trustees of the Sir Dorabji Tata Trust. It discusses the major concerns of the Trustees as they deliberated upon establishing the Hospital. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Shirish N Kavadi Source Type: research

Oral health status and prevalence of premalignant lesions in prisoners of Central Jail of Amravati, Maharashtra, India
SM Rawlani, Roshani Chawla, Sudhir Rawlani, Varsha Rathi, Ratnamala Gadge, Shashwati ChoubeIndian Journal of Cancer 2019 56(3):280-281 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: SM Rawlani Roshani Chawla Sudhir Rawlani Varsha Rathi Ratnamala Gadge Shashwati Choube Source Type: research

Papilloma virus infection in oral malignancies: An Italian experience
Sonia Cesaro, Vassilena Tsvetkova, Giulia Traverso, Mauro Cassaro, Massimo RuggeIndian Journal of Cancer 2019 56(3):279-280 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Sonia Cesaro Vassilena Tsvetkova Giulia Traverso Mauro Cassaro Massimo Rugge Source Type: research

Cervical esophagogastric anastomosis using a modified linear cutter stapler technique in esophageal cancers following neoadjuvant chemoradiation
Arvind KrishnamurthyIndian Journal of Cancer 2019 56(3):278-279 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Arvind Krishnamurthy Source Type: research

Tolerance and efficacy of branded generic pemetrexed maintenance in Indian patients of metastatic non-squamous non-small-cell lung cancer
Amit Sehrawat, KM Parthasarathy, Deni Gupta, Arun GeraIndian Journal of Cancer 2019 56(3):276-278 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Amit Sehrawat KM Parthasarathy Deni Gupta Arun Gera Source Type: research

TSC1/2 mutations as markers of response to everolimus in metastatic renal cell carcinoma: A case study
We report a case of a 67-year-old man with pazopanib-resistant metastatic renal cell carcinoma (mRCC) who showed an exceptional response to everolimus. Furthermore, this patient had TSC1 and TSC2 mutations. Only a subset of patients with mRCC respond to mTOR inhibitors and emerging evidences indicate that TSC1 and TSC2 mutations could be markers of response to mTOR inhibition. The current case study supports these accruing evidences. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Linu A Jacob Gowhar Shafi Source Type: research

8th edition AJCC and imaging TNM: Time to break-in and assert in the staging process!
Tanvi Vaidya, Subhash Desai, Abhishek MahajanIndian Journal of Cancer 2019 56(3):271-273 The current practice of oncology focuses not only on early diagnosis, staging, and treatment of cancer but also defies the concept of “One size fits all.” This paradigm shift of the 8th edition American Joint Committee on Cancer (AJCC) manual to a “personalized medicine” approach sets the stage for introducing Imaging TNM (iTNM). The iTNM would provide physicians with a clear assessment of the disease extent derived exclusively from a combination of anatomical and functional imaging modalities and simplify deci...
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Tanvi Vaidya Subhash Desai Abhishek Mahajan Source Type: research

Diagnostic application of patent blue V in sentinel lymph node biopsy for breast cancer & #8211; Is it time for a change ?
Raghavan Vidya, Ruvinder Athwal, Aarnoud P Huissoon, Richard L Baretto, Mamidipudi Thirumala KrishnaIndian Journal of Cancer 2019 56(3):269-270 Sentinel lymph node biopsy (SLNB) was introduced in the 1990s, as a minimally invasive procedure for staging the axilla with less morbidity to the traditional axillary lymph node dissection and is now standard management of the axilla in the early breast cancer. SLNB using the combined technique of blue dye and radioisotope is currently the recommended method for lymphatic mapping, and studies have shown high identification rates (IR) (>95%) and low false-negative rates (F...
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Raghavan Vidya Ruvinder Athwal Aarnoud P Huissoon Richard L Baretto Mamidipudi Thirumala Krishna Source Type: research

MCQs for & #8220;Concurrent chemoradiotherapy for head and neck cancers in older patients: Outcomes and their determinants & #8221;
HS Darling, S Jayalakshmi, Pradeep JaiswalIndian Journal of Cancer 2019 56(3):267-268 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: HS Darling S Jayalakshmi Pradeep Jaiswal Source Type: research

Concurrent chemoradiotherapy for head and neck cancers in older patients: Outcomes and their determinants
CONCLUSION: CCRT should be considered standard of care in those over seventy with good performance status. Patients with tube dependence have a higher risk of persistent disease or treatment related mortality. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Vijay K Srinivasalu Narayana Subramaniam Deepak Balasubramanian Narender Kumar Arun Philip Annu Susan KU Pushpaja Anoop R Nair Krishnakumar Thankappan Wesley Jose Subramania Iyer Pavithran Keechilat Source Type: research

A clinicopathological and immunohistochemical study of non-urothelial bladder tumours
CONCLUSION: NUBTs present with similar clinicoradiological findings; however, their histological features along with immunohistochemistry help in the definite diagnosis. One should be aware of these tumors as they frequently present diagnostic and therapeutic challenge. Most of these neoplasms present at an advanced stage. Large or multicentric randomized controlled studies are needed to know the exact behavior and prognosis of these tumors. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Sukhpreet Kaur Avinash Gupta Hanni V Gulwani Source Type: research

Promoter methylation and Ile105val polymorphism of GSTP1 gene in the modulation of colorectal cancer risk in ethnic Kashmiri population
CONCLUSION: We conclude that promoter hypermethylation in homozygous GSTP1 mutants did not elevate the risk of CRC in Kashmiri population. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Saniya Nissar Aga Syed Sameer Roohi Rasool Nissar A Chowdri Fouzia Rashid Source Type: research

The impact of kidney function on colorectal cancer patients with localized and regional diseases: An observational study from Taiwan
CONCLUSIONS: Although low eGFR is an independent risk factor for stage III colon cancer. However, the adjuvant chemotherapy impacts on stage III colon cancer patients differently according to eGFR status. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Sum-Fu Chiang Jinn-Shiun Chen Reiping Tang Chien-Yuh Yeh Pao-Shiu Hsieh Wen-Sy Tsai Jeng-Fu You Hsin-Yuan Hung Cheng-Chou Lai Jr-Rung Lin Jy-Ming Chiang Source Type: research

Use of interventional bronchoscopic treatment in small cell lung cancer
CONCLUSIONS: Multimodal interventional bronchoscopic methods seem to be a last option but may be useful in the management of advanced airway obstruction in the setting of SCLC. The choice of modality may be chosen depending upon individual patient characteristics as appropriate. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Cengiz Ozdemir Sinem N S & #246;k & #252;c & #252; Ay & #351;eg & #252;l Berk Levent Dalar Source Type: research

Prognostic significance of residual nodal burden using lymph node ratio in locally advanced breast cancer after neoadjuvant chemotherapy
CONCLUSION: Residual nodal disease after NAC analysed by LNRC or LNR = 0.25 cut-off value, is prognostic and can discriminate between favourable and unfavourable outcomes for TNBC and Her2+ breast cancers. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Reshu Agarwal Arun Philip Keechilat Pavithran Anupama Rajanbabu Gaurav Goel DK Vijaykumar Source Type: research

Community engaged breast cancer screening program in Kannur District, Kerala, India: A ray of hope for early diagnosis and treatment
CONCLUSION: Community participation with the engagement of the health system and local self-government are required for implementing a comprehensive cancer screening strategy. Breast-cancer screening program using local volunteers for early detection is feasible in low-income settings, thereby improving survival. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Neethu Ambali Parambil Sairu Philip Jaya Prasad Tripathy Phinse M Philip Karthickeyan Duraisamy Satheesan Balasubramanian Source Type: research

Role of serum HE4 as a prognostic marker in carcinoma of the ovary
CONCLUSION: HE4 levels have similar sensitivity but more specificity when compared with CA125 in diagnosing recurrent ovarian cancer. A >80% decline in HE4 levels during treatment predicts better PFS and can help in prognostication. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Manikandan Lakshmanan Vijay Kumar Arun Chaturvedi Sanjeev Misra Sameer Gupta Naseem Akhtar Shiv Rajan Kavitha Jain Sudeep Garg Source Type: research

A prospective, randomized study to compare the combination of imatinib and cytarabine versus imatinib alone in newly diagnosed patients with chronic phase chronic myeloid leukemia
CONCLUSION: Imatinib with low-dose ara-c can be considered as a potential first-line treatment option for CML-CP. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Priyanka Samal Prantar Chakrabarti Uttam K Nath Source Type: research

Pazopanib efficacy and toxicity in a metastatic sarcoma cohort: Are Indian patients different ?
CONCLUSIONS: The spectrum of adverse events in Indian patients at doses lower than the recommended dose is distinctly different from the western population. However, this unique toxicity profile needs to be validated in prospective studies. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Aparna Sharma Ilavarasi Vanidassane Aditi Aggarwal Asit Ranjan Mridha Rambha Pandey Ekta Dhamija Adarsh Barwad Sameer Rastogi Source Type: research

Evaluat & #305;on of hypofract & #305;onated stereotact & #305;c rad & #305;otherapy (HFSRT) to the resect & #305;on cav & #305;ty after surg & #305;cal resect & #305;on of bra & #305;n metastases: A s & #305;ngle center exper & #305;ence
CONCLUSION: HFSRT to the resection cavity offers a safe and effective adjuvant treatment for patients undergoing surgical resection of brain metastasis. With comparable local control rates, HFSRT may serve as a viable alternative to whole brain irradiation. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Ferrat Dincoglan Omer Sager Bora Uysal Selcuk Demiral Hakan Gamsiz Esin G & #252;ndem Yelda Elcim Bahar Dirican Murat Beyzadeoglu Source Type: research

WT1 in astrocytomas: Comprehensive evaluation of immunohistochemical expression and its potential utility in different histological grades
CONCLUSION: This study supports the oncogenic role of WT1 in astrocytomas. WT1 was found to be valuable in distinguishing different grades of astrocytomas. WT1 can aid in differentiating neoplastic process from reactive gliosis, particularly in recurrent tumors. Higher expression in glioblastomas supports its immunotherapy potential. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Aakriti Manocha Sunila Jain Source Type: research

Shared decision making and cancer screening
Filipe Prazeres, Elisa MartinsIndian Journal of Cancer 2019 56(3):195-196 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - July 19, 2019 Category: Cancer & Oncology Authors: Filipe Prazeres Elisa Martins Source Type: research

News in brief
Indian Journal of Cancer 2019 56(2):192-194 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Source Type: research

The bright hour: A memoir of living and dying
Nilakshi BiswasIndian Journal of Cancer 2019 56(2):191-191 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Nilakshi Biswas Source Type: research

The wait of expectation
Vidya Viswanath, Leela DigumartiIndian Journal of Cancer 2019 56(2):189-190 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Vidya Viswanath Leela Digumarti Source Type: research

Ketamine for post-thoracotomy pain: An old drug with new horizons
Rohini Dattatri, Nishkarsh GuptaIndian Journal of Cancer 2019 56(2):187-188 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Rohini Dattatri Nishkarsh Gupta Source Type: research

Ketamine-an essential component of postoperative pain management following oncosurgeries: TMH experience
Pritish P Kumbhare, Sumitra G Bakshi, Renuka PurohitIndian Journal of Cancer 2019 56(2):186-186 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Pritish P Kumbhare Sumitra G Bakshi Renuka Purohit Source Type: research

Renal metastasis of lung cancer mimicking renal infarction
Keisuke Watanabe, Kentaro Yumoto, Takeshi KanekoIndian Journal of Cancer 2019 56(2):185-185 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Keisuke Watanabe Kentaro Yumoto Takeshi Kaneko Source Type: research

The rising incidence of papillary thyroid cancer: More cancers or more assessments ?
Francesca Galuppini, Gianmaria Pennelli, Massimo RuggeIndian Journal of Cancer 2019 56(2):183-184 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Francesca Galuppini Gianmaria Pennelli Massimo Rugge Source Type: research

Cancer surveillance of the indigenous population in India: Much needed
Mukund Namdev Sable, Tushar MishraIndian Journal of Cancer 2019 56(2):182-183 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Mukund Namdev Sable Tushar Mishra Source Type: research

Gall bladder cancer in Delhi - some thoughts
Manigreeva KrishnatreyaIndian Journal of Cancer 2019 56(2):182-182 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Manigreeva Krishnatreya Source Type: research

Severe hyperlipidemia in a case of acute lymphoblastic leukemia
Rimjhim Sonowal, Vineeta GuptaIndian Journal of Cancer 2019 56(2):180-181 Severe hyperlipidemia (>1000 mg/dL) at initial presentation of acute lymphoblastic leukemia (ALL) is rare. Cases of hyperlipidemia during therapy for childhood ALL where they were secondary to L-asparaginase or steroids have been described. This is a case report of a one-and-half-year-old boy who presented to us with fever, abdominal distension, severe pallor, and hepatosplenomegaly. Although his investigations were suggestive of ALL, the initial blood samples were found to be grossly lipemic. The lipid profile was abnormal, showing severe hyper...
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Rimjhim Sonowal Vineeta Gupta Source Type: research

Concomitant RAS and BRAF mutation in colorectal cancer - A report of 7 cases
Ozturk Ates, Suayib YalcinIndian Journal of Cancer 2019 56(2):176-179 Rat sarcoma viral oncogene homolog (RAS) and B-Raf murine sarcoma viral oncogene homolog B1 (BRAF) are members of the same signaling pathway (RAS-RAF-mitogen-activated protein kinase (MAPK) in colorectal cancer (CRC). It is generally assumed that BRAF mutations are seen only with wild-type RAS in CRC. But RAS and BRAF are not mutually exclusive. We have identified concomitant BRAF and RAS mutations in seven patients. DNA was extracted from formalin-fixed paraffin-embedded tumor tissue and the mutation status of the RAS gene (exons 2, 3, 4) and BRAF (exo...
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Ozturk Ates Suayib Yalcin Source Type: research

Medullary and papillary thyroid carcinomas in a patient with a C634Y mutation in the RET proto-oncogene: A case report
Yan Ding, Jun Feng, Xun-hua Xu, Jun Yao, Rong-Biao YingIndian Journal of Cancer 2019 56(2):173-175 A 41 year old man presented with a familial history of multiple endocrine neoplasia type 2A (MEN2A) and severe hypertension. Rearranged during transfection (RET) gene sequencing confirmed a Cys634Tyr mutation of TGC to TAC. Total thyroidectomy and bilateral neck dissection were performed and the pathological assessment revealed a medullary thyroid carcinoma (MTC), 0.6 cm in size on the right side (number of lymph nodes: 0/2, 0/15, 0/12, and 0/8 in areas VI, II, III, and IV, respectively) and a papillary thyroid carcinoma (PT...
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Yan Ding Jun Feng Xun-hua Xu Jun Yao Rong-Biao Ying Source Type: research

Efficacy of high-dose cytarabine and aclarubicin in combination with G-CSF regimen compared to intermediate/high-dose cytarabine and standard-dose cytarabine induction regimen for non-remission acute myeloid leukemia
CONCLUSION: Our preliminary results indicate that HD-CAG regimen may represent a better alternative option for AML patients with NR after the first course of standard induction chemotherapy. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Meiqing Lei Limin Liu Zhiming Wang Depei Wu Source Type: research

Efficacy and tolerance of thoracic radiotherapy in the oldest old patients: A case series
CONCLUSION: The study shows that RT for thoracic cancer is feasible in nonagenarians. Although the definitive benefit of RT could not be addressed here, hypofractionated therapy allowed a certain measure of control with acceptable side effects. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Beno & #238;te M & #233;ry Chloe Rancoule Avi Assouline Lounis Aissou Alexander T Falk Pierre Auberdiac Alexis Vallard Cyrus Chargari Nicolas Magn Source Type: research

Effects of some characteristics of gynecological cancer diagnosis and treatment on women & #39;s sexual life quality
CONCLUSION: The reason for significant difference in the SQoL mean score according to diagnosis over time might be that women adapted to cancer diagnosis. For this reason, the SQoL of women with a diagnosis time of < 25 months should be assessed and these women should be supported. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Buse G & #252;ler Samiye Mete Source Type: research

Fractionated stereotactic radiosurgery for locally recurrent brain metastases after failed stereotactic radiosurgery
CONCLUSION: A repeated course of radiosurgery in the form of f-SRS may be a viable therapeutic option for the management of locally recurrent brain metastases after failed upfront SRS with high LC rates and an acceptable toxicity profile despite the need for further supporting evidence. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Ferrat Dincoglan Omer Sager Selcuk Demiral Hakan Gamsiz Bora Uysal Elif Onal Ayca Ekmen Bahar Dirican Murat Beyzadeoglu Source Type: research

Financial audit of wastage of anticancer drugs: Pilot study from a tertiary care center in India
CONCLUSION: To the best of authors' knowledge, this is the first study from India and the results indicate that the financial impact of anticancer drug wastage was substantial. Attempts should be directed at minimizing the wastage and cost savings without risking patients' treatment regimen and administering effective dose schedule. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Veena Reshma D & #39;Souza Princy Louis Palatty Thomas George Mohammed Adnan Suresh Rao Manjeshwar Shrinath Baliga Source Type: research

MCQs for & #8220;Analysis of clinicopathological and immunohistochemical parameters and correlation of outcomes in gastrointestinal stromal tumors & #8221;
HS Darling, S Jayalakshmi, Pradeep JaiswalIndian Journal of Cancer 2019 56(2):144-145 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: HS Darling S Jayalakshmi Pradeep Jaiswal Source Type: research

Analysis of clinicopathological and immunohistochemical parameters and correlation of outcomes in gastrointestinal stromal tumors
CONCLUSIONS: GISTs had a wide spectrum of presentation, and immunohistopathological features with organ sparing resection were conceivable in maximum. Nuclear pleomorphism may be considered as an important variable to predict recurrence in addition to malignant potential of tumors. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Vaibhav Kumar Varshney Rakesh Kumar Gupta Sundeep Singh Saluja Ila Tyagi Pramod Kumar Mishra Vineeta V Batra Source Type: research

Association of serum level of vitamin D and VDR polymorphism Fok1 with the risk or survival of pancreatic cancer in Egyptian population
CONCLUSION: Low serum vitamin D or VDR-SNP is not a risk factor for PC in Egyptian patients. Recommendations to increase vitamin D concentrations in healthy persons for the prevention of cancer and improving overall survival should be carefully considered. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Amal Ahmed Mohamed Ahmed Moustafa Aref Soha M Talima Reham A A Elshimy Shawkat S Gerges Mohamed Meghed Fawkia Eissa Zahran Eman H EL-Adawy Sherief Abd-Elsalam Source Type: research

Survival and treatment outcomes of metaplastic breast carcinoma: Single tertiary care center experience in Pakistan
CONCLUSION: Five-year progression-free and overall survival was 79.5% and 76.3%, respectively. We report better survival outcomes when compared to series described earlier despite our patient population presenting mostly with high grade, large tumors, and half of them exhibiting nodal and hormonal involvement. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Zarka Samoon Madiha Beg Romana Idress Adnan A Jabbar Source Type: research

FISH and HER2/neu equivocal immunohistochemistry in breast carcinoma
CONCLUSION: IHC is a good screening tool for negative and positive results. Any patient targeted for trastuzumab therapy should undergo confirmation of HER2/neu equivocal status by FISH analysis. We also suggest that if a non-classical FISH pattern is seen, the test should be repeated with a non-centromeric chromosome 17 reference locus probe for better treatment planning. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Geeta Vikram Patil Okaly Dipti Panwar Kavitha Bidadli Lingappa Prasanna Kumari Abhishek Anand Prashantha Kumar Manju Hosur Chikkalingaiah Rekha Vijay Kumar Source Type: research

Optimization of sentinel lymph node identification techniques in the Indian setting: A randomized clinical trial
CONCLUSION: SLNB using MB can be recommended as the technique of choice in low-resource settings. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: V Seenu Suhani Suhani Anurag Srivastava Rajinder Parshad Sandeep Mathur Rakesh Kumar Source Type: research

Role of community health worker in a mobile health program for early detection of oral cancer
CONCLUSION: The trained CHWs can aid in identifying oral potentially malignant disorders and they can be utilized in oral cancer-screening program mHealth effectively. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: N Praveen Birur Keerthi Gurushanth Sanjana Patrick Sumsum P Sunny Shubhasini A Raghavan Shubha Gurudath Usha Hegde Vidya Tiwari Vipin Jain Mohammed Imran Pratima Rao Moni Abraham Kuriakose Source Type: research

Incidence, prevalence, and mortality associated with head and neck cancer in India: Protocol for a systematic review
DISCUSSION: This review will provide updated evidence of the current burden of HNC in India. This will guide future studies and cancer registry reports to provide holistically representative epidemiological data. SYSTEMATIC REVIEW REGISTRATION: In accordance with the guidelines, our systematic review protocol was registered with the International Prospective Register of Systematic Reviews and was assigned the registration number, CRD42017077482. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Aayush Poddar Ritchlynn Aranha Madhav Madurantakam Royam Kodiveri Muthukaliannan Gothandam Ramesh Nachimuthu Rama Jayaraj Source Type: research

& #8220;Financial audit of wastage of anticancer drugs: Pilot study from a tertiary care center of India & #8221;: A commentary
Fatih Safa Erenay, Susan HortonIndian Journal of Cancer 2019 56(2):99-100 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - May 2, 2019 Category: Cancer & Oncology Authors: Fatih Safa Erenay Susan Horton Source Type: research