News from the world of oncology
Indian Journal of Cancer 2021 58(2):312-314 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Source Type: research

Dr. V. Shanta: A cancer crusader with a mission of service above self
Arvind KrishnamurthyIndian Journal of Cancer 2021 58(2):310-311 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Arvind Krishnamurthy Source Type: research

Mimicker of malignancy, malakoplakia presenting as PI-RADS 5 lesion in mp-MRI & #8212;A case report
Abhishek Laddha, Ginil Kumar Pooleri, MR Bindhu, Appu ThomasIndian Journal of Cancer 2021 58(2):307-309 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Abhishek Laddha Ginil Kumar Pooleri MR Bindhu Appu Thomas Source Type: research

An atypical case of primary pulmonary peripheral T-cell lymphoma misdiagnosed as a pulmonary infectious disease: A case report and literature review
Liyong Shi, Yiming Zeng, Huihuang Lin, Xiaoyang ChenIndian Journal of Cancer 2021 58(2):302-306 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Liyong Shi Yiming Zeng Huihuang Lin Xiaoyang Chen Source Type: research

Laboratory findings and treatment in non-small cell lung cancer (NSCLC): Single-center report
Chhavi Rajvanshi, Aseem K Tiwari, Swati Pabbi, Geet Aggarwal, Simmi Mehra, Rajni Chauhan, Dheeraj Gautam, Ashok Kumar VaidIndian Journal of Cancer 2021 58(2):299-301 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Chhavi Rajvanshi Aseem K Tiwari Swati Pabbi Geet Aggarwal Simmi Mehra Rajni Chauhan Dheeraj Gautam Ashok Kumar Vaid Source Type: research

Frozen in time, thawed to life & #8211; A case of fertility preservation in a patient with breast carcinoma
Chithira Pulimoottil Vignarajan, Keerthana Rajasekharan, Neena MalhotraIndian Journal of Cancer 2021 58(2):296-298 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Chithira Pulimoottil Vignarajan Keerthana Rajasekharan Neena Malhotra Source Type: research

An unusual case of ectopic thyroid tissue in an adrenal gland presenting as a cyst
Shreya Bramhe, Shashi Dhawan, Neeraj DhamijaIndian Journal of Cancer 2021 58(2):294-295 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Shreya Bramhe Shashi Dhawan Neeraj Dhamija Source Type: research

Integrating psycho-oncology services in cancer care in India
This article emphasizes the importance of integrating psycho-oncology services in cancer care and attempts to define the various roles that a psycho-oncologist can play across the entire trajectory. It also highlights the indispensable role played by the oncologists' referrals in maximizing the benefits of psycho-oncology services received by patients and their caregivers. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Bincy Mathew Bidhu Kalyan Mohanti Saipriya Tewari Anusheel Munshi Source Type: research

Cancer in children: The tip of the iceberg
This article looks at the burden of pediatric cancer, examines pediatric oncology policy paralysis, and offers possible solutions for improving care for children with cancer. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Venkatraman Radhakrishnan Source Type: research

Secretory carcinoma of salivary gland origin: A recently established masquerader
Shilpi Budhiraja, Rajeev Kumar, Gaurav Khanna, Prem Sagar, Sudhir Arava, Adarsh Barwad, Asit Ranjan MridhaIndian Journal of Cancer 2021 58(2):278-284 Secretory carcinoma (SC) of the salivary gland is considered to be a low-intermediate grade tumor with the potential of locally aggressive behavior. This tumor is similar both genetically (ETV6-NTRK3 fusion) and histologically to secretory carcinoma of the breast. We intent to share our experience of four cases of SC in terms of clinical behavior, pathological features, and treatment outcome. Medical records of four cases of SC were retrieved and analyzed for clinical presen...
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Shilpi Budhiraja Rajeev Kumar Gaurav Khanna Prem Sagar Sudhir Arava Adarsh Barwad Asit Ranjan Mridha Source Type: research

Metastases from renal cell carcinoma & #8212;Report of three unpredictable cases and literature review
We report three unusual cases of metastasis from RCC. The first patient presented with metastatic clear cell adenocarcinoma in the right shoulder muscles, with unknown primary and revealed an undetected clear cell right RCC on radiology. The second patient presented with a hemorrhagic nasal metastasis of RCC. A history of nephrectomy for RCC, 10 years prior to the development of nasal metastasis was elicited. The third patient presented with axillary and later abdominal wall metastasis of papillary RCC. He had a history of RCC 3 years prior to the discovery of metastasis. RCC has the propensity to appear as a metastatic ca...
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Kiran P Malhotra Anurag Gupta Saumya Shukla Gaurav R Agarwal Hardeep S Malhotra Source Type: research

Mesenteric leiomyosarcoma in a pregnant woman: A case report and review of literature
Sanjay P Deshmukh, Minish Jain, Taher ChharchhodawalaIndian Journal of Cancer 2021 58(2):267-272 We herein describe a case of primary leiomyosarcoma of descending mesocolon mesentery in a pregnant woman. A 31-year-old woman was referred to our clinic for the presence of a suspicious mass (solid heterogenous lesion with lobulated margins) detected during routine obstetric ultrasonography (USG), growing throughout her term. Imaging in her third trimester showed a considerable increase in the size of the mass and was suspected to be malignancy of uterine origin. Tru-cut biopsy performed post-partum indicated leiomyosarcoma. ...
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Sanjay P Deshmukh Minish Jain Taher Chharchhodawala Source Type: research

Primary retroperitoneal serous adenocarcinoma: A case report of rare malignancy with literature review
We present a case of PRSAC in a 60-year-old woman. Only 11 cases of PRSAC have been reported from 1983 to 2019. Histopathological features with immunohistochemical expressions are important to diagnose PRSAC. The outcome and survival mainly depend on the possibility of surgical resection. Molecular genetics of PRSAC should also be studied in relation with its ovarian counterpart. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Thin Thin Win Saint Nway Aye Nurul Shuhada Abdul Hamad Sharifah Emilia Tuan Sharif Source Type: research

Masquerader in oncology: IgG4-related kidney disease presenting as right upper ureteric mass
We present a case of a 53-year-old woman who presented with a right upper ureteric mass. On pathologic evaluation, a diagnosis of IgG4-RD was made. In the absence of preoperative biopsy and other clinical manifestations, preoperative clinical diagnosis remains challenging and high index of suspicion and accurate pathological evaluation may help in avoiding misdiagnosis. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Abhishek Laddha Ginil K Pooleri Amrutha Thomas MR Bindhu Appu Thomas Source Type: research

Why is it important to report early possible COVID-19 PET/CT findings in cancer patients ? Explaining with a case series
Conclusion: COVID-19 may be recognised early by detecting incidental findings in PET/CT, especially in asymptomatic cancer patients. Potential complications may be prevented by early diagnosis and anticancer therapy changes. Therefore, possible COVID-19 findings in PET/CT should be reported and the patient should be referred to relevant clinician. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Duygu Tekin Emine Budak Banu Yoldas Adnan Budak Source Type: research

S100A2: A potential biomarker to differentiate malignant from tuberculous pleural effusion
Conclusion: Our results indicate that levels of S100A2 are significantly elevated in MPE, and that S100A2 may serve as a diagnostic biomarker for NSCLC patients with MPE. In further studies, we will validate our findings with a larger sample population. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Ting Wang Ning Wang Linpei Zhang Yuchun Liu Asmitananda Thakur Source Type: research

The efficacy and safety of onartuzumab in patients with solid cancers: A meta-analysis of randomized trials
Conclusion: This meta-analysis indicates that the addition of onartuzumab to the standard treatments had no definite survival benefit with increased severe toxicities in patients with solid cancer. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Bum Jun Kim Dalyong Kim Jung Han Kim Hyeong Su Kim Hyun Joo Jang Source Type: research

Robotic-assisted versus conventional laparoscopic surgery for colorectal cancer: Short-term outcomes at a single center
Conclusion: The present study suggests that colorectal cancer robotic surgery was more beneficial to patients because of a shorter postoperative recovery time of bowel function and shorter hospital stays (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Dong-ping Hu Xiao-long Zhu He Wang Wen-han Liu Yao-chun Lv Xin-long Shi Li-li Feng Wei-sheng Zhang Xiong-Fei Yang Source Type: research

Quantitative detection of SRY-Box 21 (SOX21) gene promoter methylation as a stool-based noninvasive biomarker for early diagnosis of colorectal cancer by MethyLight method
Conclusion: The results of the present study demonstrated that the stool-based assay of SOX21 gene promoter methylation has a relatively high sensitivity and specificity and it may serve as a noninvasive biomarker for early detection of CRC. However, more studies with a wide range of samples are required to further confirm the role of hypermethylation of SOX21 in the early CRC diagnosis. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Keivan Moradi Esmaeil Babaei Mohammad Ali Hosseinpour Feizi Reza Safaralizadeh Nayebali Rezvani Source Type: research

Factors affecting survival in glioblastoma patients below and above 65 years of age: A retrospective observational study
Conclusion: In the patient group above 65 years of age, the patient should be attentively selected before opting for a specific treatment, age alone should not be the sole determinant factor. Rather, by considering the KPS scores, potential aggressive treatment options should also be applied. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Berrin B Yavuz Gul Kanyilmaz Meryem Aktan Source Type: research

MCQs on & #8220;A descriptive study on prevalence of arm/shoulder problems and its impact on quality of life in breast cancer survivors & #8221;
HS Darling, Pradeep Jaiswal, Nishant Lohia, Nishant R TiwariIndian Journal of Cancer 2021 58(2):207-209 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: HS Darling Pradeep Jaiswal Nishant Lohia Nishant R Tiwari Source Type: research

A descriptive study on prevalence of arm/shoulder problems and its impact on quality of life in breast cancer survivors
Conclusion: There is a high prevalence of ASPs in BCSs. Survivorship care plans should appropriately address these issues. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Priyansh Jariwala Navneet Kaur Source Type: research

Evaluation of breathing-adapted radiation therapy for right-sided early stage breast cancer patients
Conclusion: Our study revealed that incorporation of ABC-mDIBH into adjuvant RT of right-sided ESBC patients results in significantly improved critical organ sparing. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Selcuk Demiral Omer Sager Ferrat Dincoglan Bora Uysal Hakan Gamsiz Yelda Elcim Bahar Dirican Murat Beyzadeoglu Source Type: research

Nutritional status in children with acute lymphoblastic leukemia, and its correlation with severe infection
Conclusion: Our study highlights the magnitude of undernutrition at diagnosis in ALL patients in a tertiary care centre. It also correlates nutritional status with severe infection and mortality in follow-up. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Rimjhim Sonowal Vineeta Gupta Source Type: research

Evaluation of serum procalcitonin, serum interleukin-6, and interleukin-8 as predictors of serious infection in children with febrile neutropenia and cancer
Conclusion: IL-6, IL-8, and PCT can be utilized to define a group of patients with a low risk of sepsis in view of their favorable NPV. The use of these biomarkers together can facilitate early discharge from the hospital, and the use of oral antimicrobial therapy, in turn, reducing the cost of supportive therapy in a developing country. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Arathi Srinivasan Nuthan Kumar Julius X Scott Source Type: research

Adjuvant chemotherapy in uterine carcinosarcoma: Comparison of a doublet and a triplet chemotherapeutic regimen
Conclusion: Triple-drug adjuvant chemotherapy (TIP) confers no survival advantage over doublet chemotherapy (PC), and in turn, increases the grade 3/4 toxicity in the adjuvant setting of optimally staged UCS patients. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Udip Maheshwari Suhas K Rajappa Vineet Talwar Varun Goel Prasanta K Dash Manish Sharma Pankaj Goyal Parveen Jain Venkata P B Koyyala Dinesh C Doval Source Type: research

Quality of life in long term survivors of cervical cancer: A cross sectional study
Conclusion: Cervical cancer survivors have an overall good QOL. However, certain concerns related to the sexual quality of life, symptom experience, and chronic lymphedema need to be addressed appropriately. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: TS Shylasree Rohit Ranade Abhay K Kattepur Satinder Kaur Rohit Dusane Amita Maheshwari Umesh Mahantshetty Supriya Chopra Reena Engineer Rajendra A Kerkar Source Type: research

An audit of the editorial process at the Indian Journal of Cancer: Lessons learned, and how to improve chances of acceptance of your paper
Conclusion: The study provides evidence that it is difficult to get referees. Also, a significant number of authors do not read or follow the ITC. We suggest that the time taken for a decision can be appreciably improved if these issues are addressed. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Georgiaria J Fernandes Sanjay A Pai Source Type: research

Nondisclosure of a cancer diagnosis and prognosis: Recommendations for future research and practice
Mahati Chittem, Sravannthi Maya, Shweta ChawakIndian Journal of Cancer 2021 58(2):158-164 Nondisclosure of a cancer diagnosis and prognosis is a common practice in many family-centric cultures wherein cancer is viewed negatively, resulting in family carers opposing truthful communication to patients. Oncologists comply with this request for diagnosis and/or prognosis nondisclosure owing to the cultural milieu, often choosing to describe the disease in less threatening terms such as “tumor” or “fever.” This review provides a snapshot of existing research exploring diagnosis and prognosis disclosure ...
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Mahati Chittem Sravannthi Maya Shweta Chawak Source Type: research

Papillary microcarcinoma & #8212;Management issues
Ashok R Shaha, R Michael TuttleIndian Journal of Cancer 2021 58(2):155-157 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - June 7, 2021 Category: Cancer & Oncology Authors: Ashok R Shaha R Michael Tuttle Source Type: research

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Indian Journal of Cancer 2021 58(1):149-153 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Source Type: research

News from the world of oncology
Indian Journal of Cancer 2021 58(1):147-148 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Source Type: research

A young boy with stridor and bilateral Bell & #39;s palsy
Indian Journal of Cancer 2021 58(1):145-146 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Source Type: research

Time to modify informed consent in the COVID-19 era!
Abhity Gulia, Anju Gupta, Prateek Sharma, Nishkarsh GuptaIndian Journal of Cancer 2021 58(1):143-144 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Abhity Gulia Anju Gupta Prateek Sharma Nishkarsh Gupta Source Type: research

Radiotherapy practice during the COVID-19 pandemic and nation-wide lockdown: The Indian scenario
Naveen Mummudi, Sarbani Ghosh-Laskar, Anil Tibdewal, Jai P AgarwalIndian Journal of Cancer 2021 58(1):140-142 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Naveen Mummudi Sarbani Ghosh-Laskar Anil Tibdewal Jai P Agarwal Source Type: research

Denosumab in breast cancer patients receiving aromatase inhibitors: A single-center observational study of effectiveness in adjuvant setting
Azzurra Irelli, Maria Maddalena Sirufo, Teresa Scipioni, Francesca De Pietro, Amedeo Pancotti, Lia Ginaldi, Massimo De MartinisIndian Journal of Cancer 2021 58(1):136-139 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Azzurra Irelli Maria Maddalena Sirufo Teresa Scipioni Francesca De Pietro Amedeo Pancotti Lia Ginaldi Massimo De Martinis Source Type: research

Chennai tobacco vendors compliance to India & #39;s cigarette and other tobacco products Act (COTPA) 2003 & #8212; A descriptive evaluation
V Anu, B Soundharyasri, Preman Srisruthi, KG Madhumithra, H Sreemadhumitha, A SornambigaIndian Journal of Cancer 2021 58(1):133-135 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: V Anu B Soundharyasri Preman Srisruthi KG Madhumithra H Sreemadhumitha A Sornambiga Source Type: research

Therapy-related acute promyelocytic leukemia in a patient with testicular mixed germ cell tumor
Manveen Kaur, Ranjeev Bhagat, Sanjay Gupta, Kislay DimriIndian Journal of Cancer 2021 58(1):131-132 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Manveen Kaur Ranjeev Bhagat Sanjay Gupta Kislay Dimri Source Type: research

Linking of National Health Protection Mission with cancer screening in eligible population of India
Manigreeva KrishnatreyaIndian Journal of Cancer 2021 58(1):129-130 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Manigreeva Krishnatreya Source Type: research

Psychosocial counseling of patients planned for hematopoietic stem-cell transplantation for malignant conditions & #8212;practical challenges and solutions from India
Vishnu Gopal, Smita Kayal, Biswajit Dubashi, Vikas Menon, Surendran Veeraiah, C Sivakumar, R Jayalakshmi, Bhanu Prakash Bandlamudi, Arnab Bhattacharjee, Sindhu Dahagama, D Kalpana, Divya Annadurai, Prasanth GanesanIndian Journal of Cancer 2021 58(1):122-128 Hematopoietic stem-cell transplantation (HSCT) is a life-saving procedure often performed to cure relapsed and difficult-to-treat malignancies. Only a handful of centers in India were initially involved in the delivery of these services. However, in the last decade, more than 100 centers in the private and public domain have started offering transplant services in the ...
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Vishnu Gopal Smita Kayal Biswajit Dubashi Vikas Menon Surendran Veeraiah C Sivakumar R Jayalakshmi Bhanu Prakash Bandlamudi Arnab Bhattacharjee Sindhu Dahagama D Kalpana Divya Annadurai Prasanth Ganesan Source Type: research

Psycho-oncology: My chosen journey
Sravannthi MayaIndian Journal of Cancer 2021 58(1):119-121 Before choosing psycho-oncology, there was a juncture in my life when I had to select my specialization for further education. It was overwhelming to choose one from all the areas available at that time and be solely responsible for this decision as it had a bearing on not just me, but also on my family. In 2013 (when I decided on my area of specialization), psycho-oncology was a new field. With just a belief to hold onto, that one day psycho-oncology would be widespread and welcomed in Indian cancer care, I pursued this field with dedication and passion. Despite ...
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Sravannthi Maya Source Type: research

Accelerated drug approvals in oncology: Pros and cons
Sayanta Thakur, Sandeep LahiryIndian Journal of Cancer 2021 58(1):114-118 The inevitable surge of the accelerated approval process, especially for oncology drugs, has been a success story. However, the use of surrogate end-points and its validation has been debatable over the years. Over the years, US Food and Drug Administration has been rigorously working for the validation of these end-points to capture the real clinical benefit and appropriateness of clinical study designs. However, the high cost imposed by the manufacturer attributed to the faster drug access can be prohibitive and well undermine the whole process. W...
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Sayanta Thakur Sandeep Lahiry Source Type: research

Challenging role of new agents in the treatment of ALCL
Carolina V MahuadIndian Journal of Cancer 2021 58(1):112-113 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Carolina V Mahuad Source Type: research

Successful combination of crizotinib and hematopoietic stem cell transplantation in relapsed ALK-positive ALCL
We report a case wherein a combination of crizotinib and hematopoietic stem cell transplantation (HSCT) cured a 20-year-old woman with relapsed and refractory anaplastic lymphoma kinase-positive anaplastic large cell lymphoma (ALK-positive ALCL). Although she received cyclophosphamide, doxorubicin, vincristine, prednisone, and etoposide (CHOPE) as the first-line chemotherapy from the beginning, the disease progressed rapidly with the emergence of bone marrow invasion and hemophagocytic syndrome. Vincristine, idarubicin, l-asparaginase, and prednisone (VILP) chemotherapy was not effective. Therefore, the patient received of...
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Xue Sun Xiaosheng Fang Yujie Jiang Source Type: research

Mediastinal small cell carcinoma with a metastasis to the orbit: A rare carcinoma with an unusual metastatic progression
We presented a case of solitary EOM metastasis from mediastinal small cell cancer (MSCC) for the first time. A 49-year-old man presented with hoarseness. Thorax computed tomography (CT) revealed a mediastinal mass. A fine-needle aspiration biopsy (FNAB) confirmed the diagnosis of MSCC. The patient staged as limited-stage MSCC with a positron emission computed tomography (PET-CT). The patient received radical chemo-radiotherapy (CRT). PET-CT showed a complete response after CRT. Afterward, the patient presented with double vision and a headache. Brain magnetic resonance imaging (MRI) demonstrated a 2 cm metastatic lesion at...
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Meltem Kirli Bolukbas Fatma Yalcin Musri Sibel Karaca Source Type: research

Perineum and penile invasion of recurrent prostate carcinoma shown by Ga-68 PSMA PET/CT
Zehra Pinar Koc, Pınar Pelin Özcan, Vehbi ErçolakIndian Journal of Cancer 2021 58(1):101-103 Imaging of prostate cancer has recently had new modalities. Ga-68 Prostate Specific Membrane Antigen (PSMA) Positron Emission Tomography/Computed Tomography (PET/CT) has gained important diagnostic role in the management of the patients with prostate cancer. Patients with progressively elevated serum prostate specific antigen (PSA) level may be evaluated by Ga-68 PSMA PET/CT imaging. This case report presents a seventy five year old man with diagnosis of prostate cancer and progressive serum PSA increase. Local recu...
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Zehra Pinar Koc P & #305;nar Pelin & #214;zcan Vehbi Er & #231;olak Source Type: research

A rare RET mutation in an Indian pedigree with familial medullary thyroid carcinoma
We report a rare RET mutation of c.2671T>G; p.Ser891Ala in Exon 15 of the RET gene in an Indian pedigree where seven family members out of 14 screened were found to be positive for the same. RET genetic analysis should be considered as an early approach in the diagnosis of medullary thyroid carcinoma (MTC) since it improves the prognosis and permits surveillance of other family members. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Roopa Vijayan Vasantha Nair Usha Menon Harish Kumar Source Type: research

MCQs on & #8220;Reoperation does not provide a survival advantage in patients with recurrent Glioblastoma treated with irinotecan/bevacizumab treatment & #8221;
HS Darling, Pradeep Jaiswal, Nishant Lohia, Nishant R TiwariIndian Journal of Cancer 2021 58(1):96-97 (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: HS Darling Pradeep Jaiswal Nishant Lohia Nishant R Tiwari Source Type: research

Reoperation does not provide a survival advantage in patients with recurrent Glioblastoma treated with irinotecan/bevacizumab treatment
Conclusion: The second surgery in recurrent GBM has limited effect in clinical course. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Ozlem Nuray Sever Kadir Oktay Ebru G & #252;zel Vildan Kaya Aslan G & #252;zel Mustafa Y & #305;ld & #305;r & #305;m Source Type: research

Triple intrathecal chemotherapy for leptomeningeal carcinomatosis in solid tumors: Treatment outcomes, response and their determinants
Conclusion: A triple drug combination of methotrexate, cytosine arabinoside and hydrocortisone when given intrathecally for patients with LC showed good control of symptoms and reasonable survival. It may be beneficial in patients with no brain parenchymal involvement. (Source: Indian Journal of Cancer)
Source: Indian Journal of Cancer - March 24, 2021 Category: Cancer & Oncology Authors: Vijay K Srinivasalu Narayana Subramaniam Arun Philip Wesley Jose Keechilat Pavithran Source Type: research