Prenatal Diagnosis of Ductus Arteriosus Aneurysm: A Case Report and Literature Review
AbstractThe ductus arteriosus (DA) is a vascular shunt between the main pulmonary artery and the proximal descending aorta, allowing the oxygenated blood from the placenta to bypass the fetal pulmonary circulation and supply oxygen-rich blood to the systemic circulation. Anomalies within the ductus arteriosus can compromise fetal circulation. Ductus arteriosus aneurysm (DAA) is a localized saccular or tubular dilation of the DA and is considered a rare lesion. However, many reports in the literature describe DAA in the infancy period, with limited reports describing the lesion prenatally. We diagnosed a case of ductus arte...
Source: Journal of Fetal Medicine - November 7, 2022 Category: Perinatology & Neonatology Source Type: research

Perinatal Outcomes of Fetal Growth Restriction, Classified According to the Delphi Consensus Definition: A Prospective Observational Study
AbstractFetal Growth Restriction has been redefined on the basis of biometry (Abdominal  Circumference/Estimated Fetal Weight) beyond the original definition of failure of a fetus to reach its full growth potential irrespective of its size. The Delphi consensus has standardised the definition of early and late onset FGR using size (biometry) as well as functional parameters (dopple r blood flow). The clinical validity of this consensus in terms of perinatal outcomes has yet to be tested. The aim of the study was to assess and compare the incidence and perinatal outcomes of fetal growth restriction classified by the De...
Source: Journal of Fetal Medicine - September 3, 2022 Category: Perinatology & Neonatology Source Type: research

Ectopia Cordis: Case of an Early Diagnosis and Review of Literature
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - August 24, 2022 Category: Perinatology & Neonatology Source Type: research

Fetal Endocardial Valvular and Supravalvular Calcification as a Manifestation of Anti-Ro/SSA-La/SSB Antibody Mediated Cardiac Phenotype
We report a 20 weeks fetus with multiple intracardiac calcifications, val vular calcification in the pulmonary valve and supravalvular calcification at the origin of the main pulmonary artery along with calcification in the chordae of mitral and tricuspid valve in a structurally normal heart. The mother was asymptomatic but strongly positive for anti-SSA/Ro-SSB/La an tibodies. Fetal cardiac valvular calcification is an uncommon phenotype of neonatal lupus syndrome. It is important to suspect, recognize and screen for maternal autoimmune disorders even in the absence of congenital heart block. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - August 22, 2022 Category: Perinatology & Neonatology Source Type: research

FIUVV: Associations and Outcome
AbstractTo investigate the ultrasound characteristics, associations and obstetric outcomes in pregnancies with intra-abdominal umbilical vein varix of the fetus. This was a retrospective cohort study conducted over 2  years from March 2019 to February 2021. The data collected were demographic characteristics, varix characteristics, obstetric complications (fetal growth restriction/IUFD) and neonatal outcomes. Descriptive statistics (means, standard deviations, and percentages [%]) were calculated using SPSS, ve rsion 21.0 (SPSS Inc, Chicago, USA). Over the period of 2 years, six cases of FIUVV were diagnosed putting the ...
Source: Journal of Fetal Medicine - August 20, 2022 Category: Perinatology & Neonatology Source Type: research

Altered Fetal Cardiac Function in Smoking During Pregnancy
This study aimed to evaluate fetal cardiac functions in chronic maternal smoking during pregnancy and to compare them with non-smoker pregnant women. Forty-two smoker pregnant women between 24 and 34 weeks of gestation and gestational age-matched 44 non-smoker pregnant women were enrolled in this cross-sectional study. Fetal cardiac functions were measured using conventional Doppler echocardiography. The peak velocities of the  mitral valve during early diastole (E) and atrial contraction (A) were measured, and the E/A ratio was calculated. The following time periods were also calculated; isovolumetric contraction time (...
Source: Journal of Fetal Medicine - August 19, 2022 Category: Perinatology & Neonatology Source Type: research

Meckel-Gruber Syndrome in Twin Pregnancy: A Case Report
AbstractMeckel-Gruber syndrome is a rare, OR-transitive and fatal disease. Prenatal diagnosis is important, especially in regions where consanguineous marriages are common. The classic triad of the disease is occipital meningoencephalocele, renal anomalies and postaxial polydactyly. The diagnosis is made by the presence of two of these three major features. Just over 200 cases have been reported in the world literature. The purpose of presenting our case is that all findings of the disease were detected in both fetuses in a twin pregnancy for the first time, which has not  been reported in literature. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - August 18, 2022 Category: Perinatology & Neonatology Source Type: research

Unilateral Agenesis of Diaphragm with Bilateral Renal Agenesis: An Anomaly Diagnosed Prenatally During a NT Scan (11 –14 Weeks)
We present a rare case of combined developmental anomaly which has never been reported in the literature. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - August 16, 2022 Category: Perinatology & Neonatology Source Type: research

A Comparative Study of Fetal MRI and Antenatal Ultrasound in Prenatal Diagnosis with Histopathological Correlation
AbstractThe aim of this study was to assess  the role of magnetic resonance imaging (MRI) in the diagnosis of fetal anomalies and its correlation with antenatal Ultrasound (US) and histopathology. The study was conducted in the Department of Radiodiagnosis, Basaveshwar Teaching and General Hospital attached to Mahadevappa Rampure Medical Col lege, Kalaburagi. It was conducted over 6 months and included pregnant women with suspected fetal anomalies on US. MR images were read independently by two radiologists and findings were confirmed with histopathology and post natal follow up. 15 patients underwent MRI for different...
Source: Journal of Fetal Medicine - August 13, 2022 Category: Perinatology & Neonatology Source Type: research

Centile Charts of Fetal Kidney and Adrenal Gland Length: A Prospective Study in Indian Population in the State of Bihar
The objective of this study was to obtain gestation wise data of fetal renal length and adrenal len gth for 18, 19, 20 and 21 weeks of gestation and construct a gestation age wise size chart. This was a cross sectional study of 128 consecutive normal pregnancies after exclusion of multiple gestations, maternal complications, congenital anomalies and a family history of congenial adrenal hyperpl asia. Gestational age of the fetus was calculated from fetal biometry. Measurements were made in the sagittal plane as length including renal and adrenal, longest pole to pole length of kidney and adrenal gland length calculate...
Source: Journal of Fetal Medicine - August 11, 2022 Category: Perinatology & Neonatology Source Type: research

Congenital Splenic Cyst; Video Case Presentation and Literature Review
AbstractCongenital splenic cysts have been reported to  usually regress spontaneously within a few months postnatally. A splenic cyst was detected in the ultrasonography of a 27-year-old pregnant woman at her 34th week of gestation. The size of the splenic cyst remained constant in the follow-up of the patient. In the ultrasonography performed in the postnatal 1st year, it was determined that the cyst persisted and remained the same size. There is no algorithm for the follow up of cysts in the literature, and information about congenital splenic cysts will be presented in this case report and review. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - July 27, 2022 Category: Perinatology & Neonatology Source Type: research

Conjoined Twins: Unicephalus Non-Janiceps Tetrapus Tetrabrachius
We present a G6, P5 31-year-old pregnant who was diagnosed with a unicephalus non-janiceps conjoined twins. Due to its incompatibility with life, the pregnancy was electively terminated. The  prognosis of conjoined twins depends on the location and extent of the conjoined area and the accompanying congenital anomalies of the fetuses. Early diagnosis is vital because it can help in assessing the type of conjoined twins and subsequently pre-postnatal decision making. Elective termination of non-janiceps type of conjoined twins which is incompatible with life is a justifiable possibility. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - July 17, 2022 Category: Perinatology & Neonatology Source Type: research

Phenotypic Overlap of 22q11.2 Microduplication and Noonan Syndrome in a Fetus with Increased NT, Facial Dysmorphism, and Narrow Pulmonary Trunk
We report a case of a fetus with increased NT in ultrasound and facial dysmorphism, narrow pulmonary trunk on autopsy eva luation, diagnosed to have microduplication of 22q11.2. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - July 1, 2022 Category: Perinatology & Neonatology Source Type: research

Prenatal 2-D and 3-D Ultrasound Characteristics of a Case of Fetal Orofacial Macrocystic Lymphatic Malformation and its Postnatal Management with Intralesional Bleomycin
We report a case of fetal orofacial lymphatic malformation detected in the mid-trimester anomaly scan with details of two- and three-dimensional imaging, prenatal counseling, cytogenetic workup, serial ultrasound surveillance, postnatal magnetic resonance imaging, and management with an intra-lesional sclerosing agent. The case depicts the strategic importance of multidisciplinary inputs in managing cases of prenatally diagnosed oral-cervical masses for optimizing perinatal outcome. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - June 6, 2022 Category: Perinatology & Neonatology Source Type: research

Fetal 3D Imaging and HDlive Silhouette in Unraveling a Rare Case of Gall Bladder Anomaly with Fetal MRI Correlation
AbstractCurrent technology and rapidly evolving Three-dimensional (3D) and Four-dimensional (4D) ultrasound techniques with advanced High Definition live (HD live) application has made Fetal medicine accomplishable. The introduction of high-frequency probes and evolution from hand swept slice acquisition to mechanically oscillating to electronically oscillating transducers with complex post-processing algorithms has led to the visualization of 3D view or real-time 3D view (4D) of fetal structures. In this review, we present a rare antenatal case of duplication of the gall bladder, highlight the utility of 3D/4D imaging and...
Source: Journal of Fetal Medicine - June 1, 2022 Category: Perinatology & Neonatology Source Type: research