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A 2023 International Survey of Clinical Practice Patterns in the Management of Graves' Disease: A Decade of Change
CONCLUSIONS: Paradigm shifts have occurred in the management of uncomplicated GD and its variants, as well as the response to persistent and recurrent hyperthyroidism.PMID:38577717 | DOI:10.1210/clinem/dgae222 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 5, 2024 Category: Endocrinology Authors: Danilo Villagelin David S Cooper Henry B Burch Source Type: research

A Novel TSHR Gene Mutation in a Family with Non-autoimmune Hyperthyroidism
CONCLUSIONS: This novel TSHR variant is associated with T3 toxicosis during childhood. Therefore, early identification and treatment may improve patient outcomes.PMID:38566871 | PMC:PMC10983094 | DOI:10.5455/medarh.2024.78.154-158 (Source: Cancer Control)
Source: Cancer Control - April 3, 2024 Category: Cancer & Oncology Authors: Tamara Kufoof Catherine Luxford Kishani Kannangara Roderick Clifton-Bligh Kim C Donaghue Source Type: research

The status of nuclear medicine in China: the first official national survey
ConclusionThese results of the first official survey towards current status of nuclear medicine in China are the foundation for the establishment of the quality control management system. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research

Lipid Profile Evolution in Graves ’ Disease Treated with Titration Regimen of Anti-Thyroid Drugs Versus Block and Replace Regimen
In this study were included 149 medically treated GD patients, aged+>+18 years. Pregnant women and patients treated with radioactive iodine therapy or partial/total thyroidectomy were excluded. Patients were divided into 2 subgroups: titration (A) and block and replace (B) therapy, according to the ATD regimen used. Thyroid and metabolic profile was measured at baseline and at least one visit during medical treatment. The whole group included 122 (81.87%) females (F) and 27 (18.12%) males (M), ratio F:M=4.5:1. As expected, at the time of diagnosis, ...
Source: Hormone and Metabolic Research - April 2, 2024 Category: Endocrinology Authors: Stancu, Ana-Maria Pop, Oana Purice, Mariana Badiu, Corin Tags: Original Article: Endocrine Care Source Type: research

The status of nuclear medicine in China: the first official national survey
CONCLUSION: These results of the first official survey towards current status of nuclear medicine in China are the foundation for the establishment of the quality control management system.PMID:38561514 | DOI:10.1007/s00259-024-06687-w (Source: Molecular Medicine)
Source: Molecular Medicine - April 1, 2024 Category: Molecular Biology Authors: Haiqiong Zhang Jin Zheng Nan Hu Yu Liu Guangjie Yang Meixi Liu Hongli Jing Li Huo Source Type: research

The status of nuclear medicine in China: the first official national survey
CONCLUSION: These results of the first official survey towards current status of nuclear medicine in China are the foundation for the establishment of the quality control management system.PMID:38561514 | DOI:10.1007/s00259-024-06687-w (Source: Cancer Control)
Source: Cancer Control - April 1, 2024 Category: Cancer & Oncology Authors: Haiqiong Zhang Jin Zheng Nan Hu Yu Liu Guangjie Yang Meixi Liu Hongli Jing Li Huo Source Type: research

The Accomplishments and Legacy of Saul Hertz, MD
This article is a comprehensive review of the accomplishments of Saul Hertz. Extensive use of primary-source verification has clarified several issues, including the question of whether Hertz alone conceived and asked the pivotal question: "Could iodine be made radioactive artificially?"; on what date RAI was first used to treat hyperthyroidism; and why 2 articles on the first use of RAI for treatment of hyperthyroidism, from 2 different sets of authors from the same department of the same institution, appeared adjacent to each other in the same issue of the Journal of the American Medical Association in 1946. Our review a...
Source: Journal of Nuclear Medicine - April 1, 2024 Category: Nuclear Medicine Authors: Greenspan, B. S., Hofman, M. S., Buscombe, J. Tags: Special Contributions Source Type: research

Effective TRIAC treatment of a THR β-mutated patient with thyroid hormone resistance
AbstractResistance to thyroid hormone (RTH) is a rare autosomal dominant disease characterized by an alteration of thyroid hormone negative feedback, usually as a consequence of a mutation in the thyroid hormone receptor-b gene (THR β). It is characterized by high variability of clinical manifestations, ranging from isolated abnormal thyroid function tests without symptoms to severe and impaired clinical conditions. Here we report the case of a woman who was diagnosed with RTH β when she was 35 years old and was treated with 3,5,3-triiodiothyroacetic acid (TRIAC) because of the onset of clinical symptoms of hyperthyroidi...
Source: Endocrine - April 1, 2024 Category: Endocrinology Source Type: research