Risk of recurrence at the time of withdrawal of short- or long-term methimazole therapy in patients with Graves ’ hyperthyroidism: a randomized trial and a risk-scoring model
ConclusionA relapse-free state was achieved in 83% of patients with Graves ’ hyperthyroidism 84 months after cessation of long-term methimazole treatment which could be predicted by some significant predictors in a simple risk-scoring system. (Source: Endocrine)
Source: Endocrine - January 2, 2024 Category: Endocrinology Source Type: research
Thyroid Dysfunction and Chronic Kidney Disease: Unravelling the Connection
In a high-quality epidemiologic study published in the current issue of Mayo Clinic Proceedings, You et al1 provide fresh evidence for an important influence of thyroid dysfunction on the development and progression of chronic kidney disease (CKD). As a starting point for considering the potential significance of their findings, it is important to appreciate that thyroid dysfunction is a common and often inadequately treated health problem. In the Colorado thyroid disease prevalence study, 5.9% of participants had thyroid dysfunction and were receiving treatment; of these, 60.1%, 0.7%, 17.6%, 0.9%, and 20.7%, respectivel...
Source: Mayo Clinic Proceedings - January 1, 2024 Category: Internal Medicine Authors: Tom ás P. Griffin, Matthew D. Griffin Tags: Editorial Source Type: research
Thyroid Storm In Heart Failure: A Case Report
Thyroid storm (TS) is a rare presentation of hyperthyroidism. Heart failure (HF) is the leading cause of death. Hyperthyroidism is usually related to high-output HF and rarely to low-output HF secondary to dilated thyrotoxic cardiomyopathy (DTC). Burch-Wartofsky criteria is used to diagnose TS. Management includes anti-thyroid drugs, b blockers, iodine and steroids. The use of beta blockers proves challenging given their negative chronotropic and inotropic effects. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Priscilla Sigua Arce, Khalil Murad Tags: 140 Source Type: research
Maternal Thyroid Dysfunction During Pregnancy as an Etiologic Factor in Autism Spectrum Disorder: Challenges and Opportunities for Research
CONCLUSIONS: Overall, evidence supported a positive association between maternal thyroid dysfunction during pregnancy and ASD outcomes in the child, especially for hypothyroidism. Future studies could reduce misclassification bias by using laboratory measures instead of medical records to ascertain thyroid dysfunction and evaluating children for ASD at an age when it can be reliably detected. Survival bias could be further mitigated by adjusting models for more factors associated with fetal survival and ASD. Additional research is needed to comprehensively understand the roles of maternal levothyroxine treatment, iodine de...
Source: Thyroid : official journal of the American Thyroid Association - December 27, 2023 Category: Endocrinology Authors: Zoe B Kaplan Elizabeth N Pearce Sun Y Lee Hyeong Moo Shin Rebecca J Schmidt Source Type: research
Total Thyroidectomy while on Extracorporeal Membrane Oxygenation for Thyroid Storm
We present the first case reported of total thyroidectomy successfully performed while on ECMO for thyroid storm in a 32-year-old male. This case highlights the challenges of managing refractory thyroid storm with multi-organ failure. We demonstrate that total thyroidectomy may still be safely performed while on ECMO for thyroid storm, if steps are taken to optimise the patient perioperatively, with careful surgical and anaesthesia planning. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - December 27, 2023 Category: ENT & OMF Source Type: research
