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First study of Seoul virus (SEOV) in urban rodents from newly urbanized areas of Gran La Plata, Argentina
Braz J Infect Dis. 2022 Dec 19:102730. doi: 10.1016/j.bjid.2022.102730. Online ahead of print.ABSTRACTAlterations of ecosystems have deep effects on the distribution of parasites. Big cities of Argentina present structural features that favor the presence of synanthropic species, acting as source of zoonotic diseases, for example in urban rodents: the Norway rat (Rattus norvegicus) and the black rat (R. rattus). One of the important zoonotic pathogens related are the RNA virus Hantavirus, with high prevalence rates in South America. The aim of this study was to explore and identify the presence of Hantavirus in urban roden...
Source: Braz J Infect Dis - December 22, 2022 Category: Infectious Diseases Authors: Bruno Fitte Julia Brignone Carina Sen Mar ía Del Rosario Robles Source Type: research

Hantavirus Brno loanvirus is highly specific to the common noctule bat (Nyctalus noctula) and widespread in Central Europe
In conclusion, this study demonstrates a broader distribution of BRNV in common noctules in Central Europe, but at low to moderate prevalence. Additional studies are needed to prove the zoonotic potential of this hantavirus and evaluate its transmission within bat populations. (Source: Virus Genes)
Source: Virus Genes - December 21, 2022 Category: Genetics & Stem Cells Source Type: research

Role of Seaports and Imported Rats in Seoul Hantavirus Circulation, Africa
G. Castel et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - December 18, 2022 Category: Infectious Diseases Source Type: research

Distribution, frequency and clinical presentation of leptospirosis and coinfections: a systematic review protocol
Introduction Leptospirosis is a zoonotic disease with high prevalence in low-income and middle-income countries and tropical and subtropical regions. The clinical symptoms of the disease are similar to symptoms presented by other endemic infectious diseases that could be present simultaneously. Thus, leptospirosis could be masked by similar infections like dengue, malaria, hantavirus, melioidosis and borreliosis, among others. Therefore, leptospirosis could present itself as an under-reported infection or as a coinfection with another pathogen, as has been reported in the literature. However, there is a lack of documented ...
Source: BMJ Open - December 16, 2022 Category: General Medicine Authors: Parra Barrera, E. L., Bello, S., Gallego-Lopez, G. M., Atero, N., Reyes Santamaria, E., Bautista, A. Tags: Open access, Infectious diseases Source Type: research

An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo
Hantaan virus (HTNV) is the etiological pathogen of hemorrhagic fever with renal syndrome in East Asia. There are currently no effective therapeutics approved for HTNV and other hantavirus infections. We found that griffithsin (GRFT), an algae-derived lectin with broad-spectrum antiviral activity against various enveloped viruses, can inhibit the growth and spread of HTNV. In vitro experiments using recombinant vesicular stomatitis virus (rVSV) with HTNV glycoproteins as a model revealed that the GRFT inhibited the entry of rVSV-HTNV-G into host cells. In addition, we demonstrated that GRFT prevented authentic HTNV infecti...
Source: Frontiers in cellular and infection microbiology - December 12, 2022 Category: Microbiology Source Type: research

Real-time reverse transcription recombinase polymerase amplification for rapid detection of murine hepatitis virus
ConclusionThe RT-RPA assay offers an alternative tool for simple, rapid, and reliable detection of MHV in laboratory mice and has significant potential for application in laboratories. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - December 2, 2022 Category: Microbiology Source Type: research

Impact of early ECMO support on survival of patients with Hantavirus cardiopulmonary syndrome in Chile.
Conclusion. Early management of patients with HCPS at the national referral center for ECMO and early ECMO support significantly decrease mortality. (Source: European Respiratory Journal)
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Arancibia Hernandez, F., Fritz, R., Sepulveda, C., Gavilan, J., Espinoza, C., Ossandon, E., Concha, M., Iturra, S. Tags: 02.01 - Acute critical care Source Type: research

IJERPH, Vol. 19, Pages 15147: Biology, Systematics, Microbiome, Pathogen Transmission and Control of Chiggers (Acari: Trombiculidae, Leeuwenhoekiidae) with Emphasis on the United States
usamy Chiggers are the larval stage of Trombiculidae and Leeuwenhoekiidae mites of medical and veterinary importance. Some species in the genus Leptotrombidium and Herpetacarus vector Orientia species, the bacteria that causes scrub typhus disease in humans. Scrub typhus is a life-threatening, febrile disease. Chigger bites can also cause dermatitis. There were 248 chigger species reported from the US from almost every state. However, there are large gaps in our knowledge of the life history of other stages of development. North American wide morphological keys are needed for better species identification, and molecula...
Source: International Journal of Environmental Research and Public Health - November 17, 2022 Category: Environmental Health Authors: Kaiying Chen R. Michael Roe Loganathan Ponnusamy Tags: Review Source Type: research

Correction: Trends and focuses of hantavirus researches: a global bibliometric analysis and visualization from 1980 to 2020
(Source: Archives of Public Health)
Source: Archives of Public Health - November 17, 2022 Category: International Medicine & Public Health Source Type: research

Integrativesubtractive proteomics, immunoinformatics, docking, and simulation approaches reveal candidate vaccine against Sin Nombre orthohantavirus
The emergence of Sin Nombre orthohantavirus, an etiological agent of hantavirus cardiopulmonary syndrome, exacerbates the situation and imposes a heavy financial burden on healthcare organizations. Multidrug-resistant forms of the disease are prevalent, and there is currently no licensed commercial vaccine. Due to the numerous limitations of experimental vaccines, vaccines against various bacterial and viral diseases have developed via computational vaccine design. Several subtractive proteomics, immunoinformatics, docking, and simulation approaches were used in this study to develop a multi-epitope–based vaccine against...
Source: Frontiers in Immunology - November 11, 2022 Category: Allergy & Immunology Source Type: research

Hantaan virus-induced elevation of plasma osteoprotegerin and its clinical implications in hemorrhagic fever with renal syndrome
Hemorrhagic fever with renal syndrome (HFRS) has gained widespread attention as a major public health concern (Brocato and Hooper, 2019). China is a severe endemic area where patients with HFRS, especially those infected with the Hantaan virus (HTNV) and Seoul virus, account for 90% of the total global cases (Jiang et al., 2017). Although hantavirus infections do not disrupt the vascular endothelium, the underlying pathogene sis of HFRS is undoubtedly related to increased vascular permeability and pronounced thrombocytopenia (Noack et al. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - November 9, 2022 Category: Infectious Diseases Authors: Kang Tang, Yusi Zhang, Chunmei Zhang, Haifeng Hu, Ran Zhuang, Boquan Jin, Yun Zhang, Ying Ma Source Type: research

Evidence of hantavirus circulation among the Iranian population: An emerging neglected tropical disease
Ann Med Surg (Lond). 2022 Oct 31;83:104809. doi: 10.1016/j.amsu.2022.104809. eCollection 2022 Nov.NO ABSTRACTPMID:36345418 | PMC:PMC9636438 | DOI:10.1016/j.amsu.2022.104809 (Source: Annals of Medicine)
Source: Annals of Medicine - November 8, 2022 Category: Internal Medicine Authors: Mohsen Karbalaei Saeed Sahebi Masoud Keikha Source Type: research