Fatal acute undifferentiated febrile illness among clinically suspected leptospirosis cases in Colombia, 2016 –2019
Conclusions/SignificanceThis study underscores the importance of early and accurate recognition of leptospirosis to prevent mortalities. Moreover, it draws attention to the existence of other febrile syndromes in Colombia, including rickettsiosis and brucellosis, that currently lack sufficient human surveillance and regular reporting. Expanding laboratory surveillance to include viruses such as Hantavirus, Mayaro virus, Oropouche virus, and West Nile virus is crucial. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - October 16, 2023 Category: Tropical Medicine Authors: Eliana L. Parra Barrera Source Type: research
Hantavirus: an overview and advancements in therapeutic approaches for infection
Hantaviruses are a significant and emerging global public health threat, impacting more than 200,000 individuals worldwide each year. The single-stranded RNA viruses belong to the Hantaviridae family and are responsible for causing two acute febrile diseases in humans: Hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). Currently, there are no licensed treatments or vaccines available globally for HTNV infection. Various candidate drugs have shown efficacy in increasing survival rates during the early stages of HTNV infection. Some of these drugs include lactoferrin, ribavirin, ETAR, favip...
Source: Frontiers in Microbiology - October 12, 2023 Category: Microbiology Source Type: research
Viruses, Vol. 15, Pages 1995: Assessing Pulmonary Epithelial Damage in Hantavirus Cardiopulmonary Syndrome: Challenging the Predominant Role of Vascular Endothelium through sRAGE as a Potential Biomarker
This study explores the potential of soluble Receptors for Advanced Glycation End-products (sRAGE) as a biomarker for assessing pulmonary epithelial damage in severe HCPS, challenging the prevailing view that endothelial dysfunction is the sole driver of this syndrome. We conducted a cross-sectional study on critically ill HCPS patients, categorizing them into mild HCPS, severe HCPS, and negative control groups. Plasma sRAGE levels were measured, revealing significant differences between the severe HCPS group and controls. Our findings suggest that sRAGE holds promise as an indicator of pulmonary epithelial injury in HCPS ...
Source: Viruses - September 26, 2023 Category: Virology Authors: Gabriela Meza-Fuentes Ren é López Cecilia Vial Lina Jimena Cortes Mauricio A. Retamal Iris Delgado Pablo Vial Tags: Brief Report Source Type: research
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters
Emerg Infect Dis. 2023 Oct;29(10):2159-2163. doi: 10.3201/eid2910.230544.ABSTRACTSeveral occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor shedding has been investigated. We demonstrate horizontal virus transmission and show that Andes virus is shed efficiently from both inoculated and contact-infected hamsters.PMID:37735788 | DOI:10.3201/eid2910.230544 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Silke A Riesle-Sbarbaro Norman Kirchoff Katharina Hansen-Kant Alice Stern Andreas Kurth Joseph B Prescott Source Type: research
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters
Emerg Infect Dis. 2023 Oct;29(10):2159-2163. doi: 10.3201/eid2910.230544.ABSTRACTSeveral occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor shedding has been investigated. We demonstrate horizontal virus transmission and show that Andes virus is shed efficiently from both inoculated and contact-infected hamsters.PMID:37735788 | DOI:10.3201/eid2910.230544 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Silke A Riesle-Sbarbaro Norman Kirchoff Katharina Hansen-Kant Alice Stern Andreas Kurth Joseph B Prescott Source Type: research
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters
Emerg Infect Dis. 2023 Oct;29(10):2159-2163. doi: 10.3201/eid2910.230544.ABSTRACTSeveral occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor shedding has been investigated. We demonstrate horizontal virus transmission and show that Andes virus is shed efficiently from both inoculated and contact-infected hamsters.PMID:37735788 | DOI:10.3201/eid2910.230544 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Silke A Riesle-Sbarbaro Norman Kirchoff Katharina Hansen-Kant Alice Stern Andreas Kurth Joseph B Prescott Source Type: research
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters
Emerg Infect Dis. 2023 Oct;29(10):2159-2163. doi: 10.3201/eid2910.230544.ABSTRACTSeveral occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor shedding has been investigated. We demonstrate horizontal virus transmission and show that Andes virus is shed efficiently from both inoculated and contact-infected hamsters.PMID:37735788 | DOI:10.3201/eid2910.230544 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Silke A Riesle-Sbarbaro Norman Kirchoff Katharina Hansen-Kant Alice Stern Andreas Kurth Joseph B Prescott Source Type: research
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters
Emerg Infect Dis. 2023 Oct;29(10):2159-2163. doi: 10.3201/eid2910.230544.ABSTRACTSeveral occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor shedding has been investigated. We demonstrate horizontal virus transmission and show that Andes virus is shed efficiently from both inoculated and contact-infected hamsters.PMID:37735788 | PMC:PMC10521624 | DOI:10.3201/eid2910.230544 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Silke A Riesle-Sbarbaro Norman Kirchoff Katharina Hansen-Kant Alice Stern Andreas Kurth Joseph B Prescott Source Type: research
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters
Emerg Infect Dis. 2023 Oct;29(10):2159-2163. doi: 10.3201/eid2910.230544.ABSTRACTSeveral occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor shedding has been investigated. We demonstrate horizontal virus transmission and show that Andes virus is shed efficiently from both inoculated and contact-infected hamsters.PMID:37735788 | PMC:PMC10521624 | DOI:10.3201/eid2910.230544 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Silke A Riesle-Sbarbaro Norman Kirchoff Katharina Hansen-Kant Alice Stern Andreas Kurth Joseph B Prescott Source Type: research
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters
Emerg Infect Dis. 2023 Oct;29(10):2159-2163. doi: 10.3201/eid2910.230544.ABSTRACTSeveral occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor shedding has been investigated. We demonstrate horizontal virus transmission and show that Andes virus is shed efficiently from both inoculated and contact-infected hamsters.PMID:37735788 | PMC:PMC10521624 | DOI:10.3201/eid2910.230544 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Silke A Riesle-Sbarbaro Norman Kirchoff Katharina Hansen-Kant Alice Stern Andreas Kurth Joseph B Prescott Source Type: research
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters
Emerg Infect Dis. 2023 Oct;29(10):2159-2163. doi: 10.3201/eid2910.230544.ABSTRACTSeveral occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor shedding has been investigated. We demonstrate horizontal virus transmission and show that Andes virus is shed efficiently from both inoculated and contact-infected hamsters.PMID:37735788 | PMC:PMC10521624 | DOI:10.3201/eid2910.230544 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - September 22, 2023 Category: Infectious Diseases Authors: Silke A Riesle-Sbarbaro Norman Kirchoff Katharina Hansen-Kant Alice Stern Andreas Kurth Joseph B Prescott Source Type: research
Favorable course of leptospirosis and hantavirus-induced acute tubulointerstitial nephritis under corticosteroid treatment
ConclusionsLeptospirosis and hantavirus associated ATIN share common clinical and biochemical features. Due to the low incidence in Europe these infectious causes of kidney dysfunction may be overlooked. Glucocorticoids may be considered in the management of ATIN. (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - September 22, 2023 Category: Urology & Nephrology Source Type: research
The first evidence of Seoul hantavirus, hepatitis E virus and rabies virus in Rattus norvegicus in Tehran, Iran
Future Virology, Ahead of Print. (Source: Future Virology)
Source: Future Virology - September 8, 2023 Category: Virology Authors: Taher Azimi Sina Nasrollahian Sahar Sabour Nahal Hadi Leila Azimi Nourina Rahbarian Abdollah Karimi Fatemeh Fallah Roxana Mansour-Ghanaie Seyedeh Mahsan Hoseini-Alfatemi Sayyed Alireza Fahimzad Source Type: research
