TWiV 881: 50 ways to zap your virus
TWiV describes the identification of a monoclonal antibody that provides broad protection against a variety of hantaviruses, and development of an oral remdesivir-like antiviral that ameliorates viral disease in mice. (Source: virology blog)
Source: virology blog - March 27, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology COVID-19 epitope hantavirus monoclonal antibody oral antiviral pandemic remdesivir SARS-CoV-2 viruses Source Type: blogs
TWiV 668: Mice, bats, and coronaviruses with Tony Schountz
Tony Schountz joins TWiV to explain the work of his laboratory showing that deer mice can be infected with and transmit SARS-CoV-2, and how his colony of Jamaican fruit bats is being used to understand their response to virus infections. (Source: virology blog)
Source: virology blog - October 2, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus COVID-19 deer mouse fruit bat hantavirus MERS-CoV pandemic reservoir host SARS-CoV-2 viral viruses zoonosis Source Type: blogs
Rationale for Testing Anticoagulants Against COVID-19
This article originally appeared on the Timmerman Report here.
The post Rationale for Testing Anticoagulants Against COVID-19 appeared first on The Health Care Blog. (Source: The Health Care Blog)
Source: The Health Care Blog - April 16, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Patients Physicians anticoagulants cardiology coronavirus Ethan Weiss thrombosis Source Type: blogs
TWiV 583: Galveston virus hunters
Vincent and Rich travel to Galveston National Laboratory to speak with Jim LeDuc, Tom Ksiazek, and Bob Tesch about their long careers as virus hunters. Click arrow to play Download TWiV 583 (51 MB .mp3, 84 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - January 19, 2020 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology arbovirus BSL4 laboratory ebolavirus galveston national laboratory hantavirus Nipah virus select agent Texas Medical Branch viral virus hunters viruses Source Type: blogs
TWiV 578: Prometheus project
Vincent speaks with members of Prometheus, a team of academic and industrial scientists assembled to develop antibody-based therapeutics against infections caused by tick-borne Crimean-Congo hemorrhagic fever virus and rodent-borne hantaviruses, for which no approved vaccines or specific drugs are available. Click arrow to play Download TWiV 578 (55 MB .mp3, 91 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become […] (Source: virology blog)
Source: virology blog - December 15, 2019 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Crimean-Congo hemorrhagic fever virus hantavirus monoclonal antibody therapy rodent-borne virus tick-borne virus U19 grant viral viruses Source Type: blogs
On the RISE: Joshua and Caleb Marceau Use NIGMS Grant to Jump-Start Their Research Careers
A college degree was far from the minds of Joshua and Caleb Marceau growing up on a small farm on the Flathead Indian Reservation in rural northwestern Montana. Their world centered on powwows, tending cattle and chicken, fishing in streams, and working the 20-acre ranch their parents own. Despite their innate love of learning and science, the idea of applying to and paying for college seemed out of reach. Then, opportunities provided through NIGMS, mentors, and scholarships led them from a local tribal college to advanced degrees in biomedical science. Today, both Joshua and Caleb are Ph.D.-level scientists working to imp...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - October 23, 2019 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Infectious Diseases Scientific Process Training Source Type: blogs
TWiV 568: Karolinska viral
In the second episode from the Karolinska Institute in Stockholm, Vincent speaks with Jan Albert, Petter Brodin, and Anna Smed-Sörensen about their work on enterovirus D68, systems immunology, and human pulmonary viral infection and inflammation. Click arrow to play Download TWiV 568 (58 MB .mp3, 95 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - October 6, 2019 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology acute flaccid myelitis dendritic cell enterovirus D68 epidemiology hantavirus influenza virus maternal antibodies mononuclear phagocyte newborn anti-viral antibodies placenta respiratory viral infection system Source Type: blogs
TWiV 549: The church of protocadherin
Kartik Chandran and Rohit Jandra join the TWiV team to present their identification of protocadherin-1 as a cell receptor for New World hantaviruses. Click arrow to play Download TWiV 549 (62 MB .mp3, 103 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - May 26, 2019 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology cell receptor CRISPR/Cas9 hantavirus hantavirus pulmonary syndrome haploid cell line protocadherin-1 sin nombre virus viral viral pathogenesis Source Type: blogs
TWiV 527: City mouse, country mouse
The TWiV team summarizes the discovery of Sin Nombre virus, and presents evidence that neurotropic flaviviruses can cause intestinal dysmotility syndromes after systemic infection of mice. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span><span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=̶...
Source: virology blog - December 30, 2018 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology deer mouse enteric nervous system flavivirus hantavirus hantavirus pulmonary syndrome IBS inflammatory bowel syndrome intestinal dysmotility syndrome neurotropic outbreak Peromyscus maniculatus sin nombre viru Source Type: blogs
Doctors, Data, Diagnoses, and Discussions: Achieving Successful and Sustainable Personalized/Precision Medicine
The following is a guest blog post by Drew Furst, M.D., Vice President Clinical Consultants at Elsevier Clinical Solutions.
Personalized/precision medicine is a growing field and that trend shows no sign of slowing down.
In fact, a 2016 Grand View Research report estimated the global personalized medicine market was worth $1,007.88 billion in 2014, with projected growth to reach $2,452.50 billion by 2022.
As these areas of medicine become more commonplace, understanding the interactions between biological factors with a range of personal, environmental and social impacts on health is a vital step towards achieving sustaina...
Source: EMR and HIPAA - January 10, 2018 Category: Information Technology Authors: Guest Blogger Tags: Clinical Decision Support Genomics Healthcare HealthCare IT Personalized Medicine Drew Furst Elsevier Elsevier Clinical Solutions Precision Medicine Source Type: blogs
English sweat
In the current BBC adaptation of Hilary Mantel's "Wolf Hall", Thomas Cromwell loses his wife and two daughters to a mysterious and very sudden illness. All we see is that they all go to bed as usual, and then cannot be woken in the morning. There is a suggestion that there were symptoms, but we don't see them. The disease is described as "English sweating sickness", either in the programme or in something I read about it (bad note taking, can't remember my source).What was it? A search of PubMed for English sweating sickness brings up this very new article proposing that the guilty agent was h...
Source: Browsing - February 3, 2015 Category: Databases & Libraries Tags: hantavirus Source Type: blogs
TWiV 322: Postcards from the edge of the membrane
On episode #322 of the science show This Week in Virology, the TWiVodes answer listener email about hantaviruses, antivirals, H1N1 vaccine and narcolepsy, credibility of peer review, Bourbon virus, influenza vaccine, careers in virology, and much more.
You can find TWiV #322 at www.twiv.tv. (Source: virology blog)
Source: virology blog - February 1, 2015 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral Bourbon virus careers in virology crispr Dengue H1N1 hantavirus hepatitis C virus herpes simplex virus influenza vaccine influenza virus measles mumps narcolepsy NHL opossum patent peer r Source Type: blogs
Ebola: Don’t forget the patients who are left behind
Ebola virus is rampant in West Africa. So far, the death toll is around 2,296, which makes it one of the largest outbreaks ever. Ebola is what’s known as a hemorrhagic fever virus, and belongs to a large family of nasty viruses that are widespread around the world. There’s even one in the American Southwest known as hantavirus, that lives in a species of mice. Yellow fever, which killed so many before a vaccine was developed, was once widespread as far north as Detroit. Some of these viruses are extremely deadly and some less so, but all of them are dangerous and miserable to endure.
Continue reading ...
Your patients...
Source: Kevin, M.D. - Medical Weblog - September 20, 2014 Category: Journals (General) Authors: Edwin Leap, MD Tags: Conditions Infectious disease Source Type: blogs
What To Expect When You Call a Suicide Prevention Hotline
On National Suicide Prevention Day last week, many Twitter celebrities did their civic duty by retweeting the same two tweets over & over again, both pointing to suicide prevention hotlines. Some people who discuss suicide the other 364 days of the year were irritated by the superficial emphasis on hotlines—as if tweeting a hotline constituted quality support. Certainly, Twitter can be vapid. Twitter advocacy is usually about feeling charitable more than actually being charitable. But were suicide prevention hotlines as bad as people claimed?
I generally considered a hotline the last option because there are so many...
Source: The Splintered Mind by Douglas Cootey - September 21, 2013 Category: Mental Illness Tags: Coping Depression Source Type: blogs
