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Einstein Researchers Awarded Three NIH Grants Totaling $12 Million to Fight Virulent Viruses
August 11, 2017—BRONX, NY—The NIH has awarded Einstein researchers three grants totaling more than $12 million to protect against three deadly viruses—Ebola, Marburg and hantavirus. Research collaborations betweenKartik Chandran, Ph.D., professor of microbiology& immunology and the Harold and Muriel Block Faculty Scholar in Virology, andJonathan Lai, Ph.D., associate professor of biochemistry, have led to novel approaches for developing vaccines and treatments. (Source: Einstein News)
Source: Einstein News - August 11, 2017 Category: Universities & Medical Training Source Type: news

Einstein researchers awarded 3 NIH grants totaling $12 million to fight virulent viruses
(Albert Einstein College of Medicine) The NIH has awarded Einstein researchers three grants totaling more than $12 million to protect against three deadly viruses -- Ebola, Marburg and hantavirus. Research collaborations between Kartik Chandran, Ph.D., professor of microbiology& immunology and the Harold and Muriel Block Faculty Scholar in Virology, and Jonathan Lai, Ph.D. associate professor of biochemistry, have led to novel approaches for developing vaccines and treatments. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 11, 2017 Category: International Medicine & Public Health Source Type: news

Outbreak of Hantavirus Infections Kills 3 in Washington State Outbreak of Hantavirus Infections Kills 3 in Washington State
Five people have been stricken with the rare, rodent-borne hantavirus illness in Washington state since February, three of whom have died, in the state's worst outbreak of the disease in at least 18 years.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 10, 2017 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Outbreak of hantavirus infections kills three in Washington state
(Reuters) - Five people have been stricken with the rare, rodent-borne hantavirus illness in Washington state since February, three of whom have died, in the state's worst outbreak of the disease in at least 18 years, public health officials reported on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - July 7, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Cytokine profile differentiating Old World and New World hantaviral infections
(Kazan Federal University) Hantavirus infection is acute zoonosis clinically manifesting in two forms: Hemorrhagic Fever with Renal Syndrome (HFRS), caused by Old World hantaviruses, and Hantavirus pulmonary syndrome (HPS), caused by New World hantaviruses. Mild form of HFRS, Nephropaia epidemica (NE), is diagnosed in Tatarstan region of Russia, while HPS is endemic in Americas. Humans become infected by inhaling virus contaminated aerosol of urine and feces. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 15, 2017 Category: Infectious Diseases Source Type: news

Hantavirus Pulmonary Syndrome Risk Up for Some Populations
American - Indians account for 18 percent of case - patients, have higher case - fatality rates than whites (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - April 20, 2017 Category: Respiratory Medicine Tags: Infections, Pathology, Pulmonology, Journal, Source Type: news

What Health Risks Does Climate Change Pose?
Discussion Japanese encephalitis virus (JEV) is a Flavivirae, arbovirus that is endemic to many areas of Asia and the Pacific. It is estimated to affect ~70,000 people/year with ~10-15,000 deaths yearly in 20 countries, with a fatality rate of 35-40%. It can cause encephalitis and irreversible neurological morbidity. JEV is spread by Culex mosquitos which feed on swine. Increased environmental temperature and increased humidity (warm air is more moist) increases mosquito numbers, their survivability and ultimate dissemination. China has the highest rates of JEV with particular areas being more prone, as some areas co-farm ...
Source: PediatricEducation.org - March 6, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Seoul virus – United States of America and Canada
On 24 January 2017, the United States Centers for Disease Control and Prevention (CDC), through their Health Alert Network (HAN) publication, reported 8 cases of infection with Seoul virus in the states of Wisconsin (n=2) and Illinois (n=6). The first two cases were reported in early December 2016, when two home-based pet rat breeders in Wisconsin State developed an acute febrile illness, later confirmed as Seoul virus infection. Rats (Rattus norvegicus) at some facilities also tested positive for Seoul virus. Human infection with Seoul virus is not commonly found in the United States; this virus family also includes Sin N...
Source: WHO Disease Outbreaks - February 20, 2017 Category: Infectious Diseases Tags: news Source Type: news

8 People Infected in Rare U.S. Outbreak of Rat Virus
Those handling rodents in breeding facilities in 2 states contracted Seoul virus, CDC reports Source: HealthDay Related MedlinePlus Pages: Animal Diseases and Your Health, Hantavirus Infections (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - January 20, 2017 Category: Consumer Health News Source Type: news

Notes from the Field: Hantavirus Pulmonary Syndrome in a Migrant Farm Worker — Colorado, 2016
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 19, 2017 Category: American Health Source Type: news

New Mexico Sees Two More Cases of Hantavirus
“Photo” by My Name is licensed under CC0. New Mexico’s McKinley County recently announced it has confirmed two more cases of hantavirus pulmonary syndrome. They are the seventh and eight cases of hantavirus confirmed in New Mexico this year. The 59-year-old man and 29-year-old woman diagnosed have been hospitalized. Hantavirus is a disease carried by rodents and can be transmitted to humans through saliva, urine or droppings. People will often inhale the virus when cleaning up rodent droppings and nesting materials. In New Mexico, the primary culprit of hantavirus is the deer mouse, which carries the Sin...
Source: Network News - December 15, 2016 Category: Databases & Libraries Authors: NN/LM South Central Region Tags: New Mexico Public Health Source Type: news

UCLA faculty voice: We can ’t rely on luck to counter public health threats
UCLA Dr. Jonathan Fielding Dr. Jonathan Fielding, is a professor-in-residence of health policy and management in the UCLA Fielding of Public Health and pediatrics in the David Geffen School of Medicine at UCLA. He served as chair of the independent expert panel on the U.S. Department of Health and Human Services response to Ebola. This op-ed appeared in U.S. News and World Report. In 2014, we were lucky. There were only four diagnosed cases of Ebola virus in the United States. But in Africa, there were over 25,000 diagnosed cases of Ebola virus and more than 11,000 deaths, amounting to a public health tragedy. The respons...
Source: UCLA Newsroom: Health Sciences - August 18, 2016 Category: Universities & Medical Training Source Type: news

Child infected with life-threatening hantavirus after being inside rodent-infested building
Humans become infected by inhaling dust that has mixed with saliva or urine of deer mice. The newly-infected girl had been in a rodent infested building, North Dakota officials said on Wednesday. (Source: the Mail online | Health)
Source: the Mail online | Health - July 21, 2016 Category: Consumer Health News Source Type: news

Grieving family warns others of rare but deadly hantavirus
As health officials in Saskatchewan issue their annual reminder about hantavirus, Julia McIsaac would like to spare other families the grief hers has experienced since her daughter died of the disease in June 2014. (Source: CBC | Health)
Source: CBC | Health - April 22, 2016 Category: Consumer Health News Tags: News/Canada/Saskatchewan Source Type: news

AIBS Report Documents Returns from Federally Funded Research
Federally funded biological research has a strong record of producing positive outcomes for the nation, according to a new report prepared by the American Institute of Biological Sciences (AIBS). “Biological Innovation: Benefits of Federal Investments in Biology” highlights some of the innovations and technical advancements resulting from biology research. “The contributions biological scientists make to our nation are astounding, said Robert Gropp, Interim Co-Executive Director of AIBS. “From research that saves lives to discoveries that create new jobs and economic opportunities, biology research...
Source: Public Policy Reports - April 19, 2016 Category: Biology Authors: AIBS Source Type: news

Structure of a hantavirus protein as a promising model for drug design
There is no treatment for infection with the dangerous hantavirus. Scientists have now identified the three-dimensional structure of a hantavirus protein that is essential for replication of the virus. They have published their findings, providing a blueprint for the design of antiviral drugs. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 26, 2016 Category: Science Source Type: news

Structure of a hantavirus protein as a promising model for drug design
(Max Delbrück Center for Molecular Medicine in the Helmholtz Association) There is no treatment for infection with the dangerous hantavirus. Scientists at the Max Delbrück Center for Molecular Medicine (MDC) have now identified the three-dimensional structure of a hantavirus protein that is essential for replication of the virus. They have published their findings in the journal Cell Reports, providing a blueprint for the design of antiviral drugs. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 26, 2016 Category: Infectious Diseases Source Type: news

Link between small mammals and evolution of hepatitis A virus to humans discovered
(University of North Carolina at Chapel Hill) Researchers at the University of North Carolina at Chapel Hill are part of an international team led by the University of Bonn, Germany, who have found a link between the origin of hepatitis A virus (HAV) and small mammals. With the emergence of Ebola virus from bats and hantaviruses from rodents, investigators say identifying the other species infected with HAV provides novel insight into the evolution of HAV and how it spread to humans. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 3, 2015 Category: Infectious Diseases Source Type: news

Hantaviruses are highly dependent on cell membrane cholesterol to infect humans
Hantaviruses use cholesterol in cell walls to gain access into cells and infect humans, according to laboratory research. Multiple genes involved in cholesterol sensing, regulation and production, including key components to a chemical pathway called SREBP (sterol response element binding protein), are critical to hantaviruses gaining entry, the researchers found. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 30, 2015 Category: Science Source Type: news

Ecologist warns of bamboo fueling spread of hantavirus
The popularity of bamboo landscaping could increase the spread of hantavirus, researchers say, with the plant's prolific seed production creating a population boom among seed-eating deer mice that carry the disease. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 7, 2015 Category: Science Source Type: news

WSU ecologist warns of bamboo fueling spread of hantavirus
(Washington State University) Washington State University researchers say the popularity of bamboo landscaping could increase the spread of hantavirus, with the plant's prolific seed production creating a population boom among seed-eating deer mice that carry the disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 7, 2015 Category: Biology Source Type: news

First evidence of Seoul hantavirus found in wild rat population in the Netherlands
Researchers report discovering the first evidence of Seoul hantavirus (SEOV) in the wild rat population in the Netherlands. The discovery comes on the heels of similar ones in France, Belgium and the United Kingdom in recent years, and has some researchers concerned about the potential spread of the virus to humans. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 12, 2015 Category: Science Source Type: news

Cows with human chromosomes enlisted to fight hantavirus
Researchers have genetically engineered cows to produce human antibodies against the deadly hantavirus and possibly other diseases (Source: ScienceNOW)
Source: ScienceNOW - November 26, 2014 Category: Science Source Type: news

Human antibodies produced in DNA-vaccinated cows protect in lethal models of hantavirus
(US Army Medical Research Institute of Infectious Diseases) Scientists investigating the potentially deadly hantavirus have used a novel approach to developing protective antibodies against it. The research, published in Science Translational Medicine, used specially bred 'transchromosomal' cows engineered to produce fully human antibodies. Investigators immunized the cows with DNA vaccines targeting two types of hantaviruses, Andes and Sin Nombre. The team collected plasma from the cows, purified the human IgG antibodies, and tested the material, which had potent neutralizing activity against both hantaviruses. (Source: E...
Source: EurekAlert! - Biology - November 26, 2014 Category: Biology Source Type: news

Hantavirus: Symptoms, Precautions and Prevention
Hantaviruses are a group of viruses that are carried by rodents. One of these, ‘Sin Nombre virus,’ is found in deer mice in North America. Sin Nombre virus is the cause of Hantavirus Pulmonary Syndrome (HPS) in people. (Source: Disabled World)
Source: Disabled World - October 16, 2014 Category: Disability Tags: Health and Disability Source Type: news

NYC Rats Are Even Grosser Than You Thought
Rats are a part of daily life in New York as they scurry about subway tracks and garbage heaps. However, even though the creatures been neighbors of New Yorkers for centuries, researchers are still learning exactly how these rodents could affect the health of millions. In a recently released study from scientists at Columbia University, researchers confirmed the fears of every New Yorker. These ubiquitous pests are housing dangerous bacteria including E. Coli, Salmonella and viruses including the deadly Seoul Hantavirus. (Source: ABC News: Health)
Source: ABC News: Health - October 14, 2014 Category: Consumer Health News Tags: Health Source Type: news

Rats of New York and the diseases they carry
(Columbia University's Mailman School of Public Health) In the first study to look at would-be diseases carried by New York City rats, scientists at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health identified bacterial pathogens, including E. coli, Salmonella, and C. difficile, that cause mild to life-threatening gastroenteritis in people; Seoul hantavirus, which causes Ebola-like hemorrhagic fever and kidney failure in humans; and the closest relative to human hepatitis C. Results appear in the journal mBio. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 14, 2014 Category: Global & Universal Source Type: news

NIH scientists establish monkey model of hantavirus disease
(NIH/National Institute of Allergy and Infectious Diseases) National Institute of Allergy and Infectious Diseases researchers have developed an animal model of human hantavirus pulmonary syndrome in rhesus macaques, an advance that may lead to treatments, vaccines and improved methods of diagnosing the disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 28, 2014 Category: Infectious Diseases Source Type: news

Could statins be used to fight a deadly viral infection?
(University of Pennsylvania School of Medicine) Two Perelman School of Medicine microbiologists may have found a way to use statins, the well-known blockbuster cholesterol-lowering drugs, to fight the hantavirus, a mysterious and lethal microorganism that appeared suddenly in the US southwest over 20 years ago. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 11, 2014 Category: Biology Source Type: news

Cholesterol plays a critical role in hantavirus infection
Viruses mutate fast, which means they can quickly become resistant to anti-viral drugs. But viruses also depend on proteins and nutrients provided by their hosts, and therefore one strategy to identify new anti-viral drugs is to identify and target such host-cell components. Proteins involved in the regulation of cholesterol are essential for hantavirus entry into human host cells, new research shows. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 7, 2014 Category: Science Source Type: news

Cholesterol plays a critical role in hantavirus infection
(PLOS) Viruses mutate fast, which means they can quickly become resistant to anti-viral drugs. But viruses also depend on proteins and nutrients provided by their hosts, and therefore one strategy to identify new anti-viral drugs is to identify and target such host-cell components. A paper published on Feb. 6 in PLOS Pathogens reports that proteins involved in the regulation of cholesterol are essential for hantavirus entry into human host cells. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 6, 2014 Category: Infectious Diseases Source Type: news

ERGIC-53's role in virus propagation suggested by bleeding symptom
Rodent-borne pathogens like hantaviruses and arenaviruses are simple, but resourceful, and very successful at propagating. Due to a tiny genome generating a mere four proteins compared to humans' thousands, they rely on human biological machinery to do their replication dirty work, facilitating infection, plus a high mortality rate. Vermont researchers have discovered a mechanism that when targeted, may stop these deadly viruses in their tracks.A new study published in Cell Host & Microbe by the University of Vermont's Jason Botten, Ph.D. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 17, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Spanish bat study shines new light on spread of coronavirus
This article appeared in Guardian Weekly, which incorporates material from Le MondeMedical researchAnimal behaviourWildlifeMicrobiologyAnimalsInfectious diseasesHealthPaul Benkimountheguardian.com © 2013 Guardian News and Media Limited or its affiliated companies. All rights reserved. | Use of this content is subject to our Terms & Conditions | More Feeds (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - September 17, 2013 Category: Science Authors: Paul Benkimoun Tags: World news Infectious diseases Health Medical research Microbiology Animals Editorial Animal behaviour Guardian Weekly Environment Science Wildlife Source Type: news

Record incidence of hantavirus disease in Germany
2824 new cases of hantavirus disease were reported in Germany in 2012, the highest number ever in a single year. In the current issue of Deutsches �rzteblatt International, Detlev Krüger and coauthors present the main facts about this disease. Every two to three years, large outbreaks of hantavirus disease are caused by Puumala virus, which is transmitted by bank voles and is endemic to southwestern and western Germany. In the north and east of the country, hantavirus infections are caused by the Dobrava-Belgrad virus, which is transmitted by striped field mice... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 26, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Record incidence of hantavirus disease
(Deutsches Aerzteblatt International) 2824 new cases of hantavirus disease were reported in Germany in 2012, the highest number ever in a single year. In the current issue of Deutsches Ärzteblatt International, Detlev Krüger and coauthors present the main facts about this disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 24, 2013 Category: Global & Universal Source Type: news

Spillover Of Infectious Diseases Among Wildlife, Domestic Animals And People; Links Found Between Environment And Human Health
West Nile virus, Lyme disease and hantavirus. All are infectious diseases spreading in animals and in people. Is human interaction with the environment somehow responsible for the increase in these diseases? The ecology and evolution of infectious diseases will be highlighted at two symposia at the Ecological Society of America's annual meeting, held from Aug. 5-9 in Minneapolis, Minn. One symposium will address human influences on viral and bacterial diseases through alteration of landscapes and ecological processes... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 2, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Interplay of ecology, infectious disease, wildlife and human health featured at annual conference
(National Science Foundation) West Nile virus, Lyme disease and hantavirus. All are infectious diseases spreading in animals and in people. Is human interaction with the environment somehow responsible for the increase in these diseases? (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 28, 2013 Category: Global & Universal Source Type: news

High-Dose Steroids for Hantavirus Cardiopulmonary SyndromeHigh-Dose Steroids for Hantavirus Cardiopulmonary Syndrome
High-dose IV methylprednisolone is not helpful against hantavirus cardiopulmonary syndrome (HCPS), researchers from Chile report. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 24, 2013 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Yosemite makeover seeks to keep hantavirus at bay
Last year, three visitors died and six became ill when they were infected by the rodent-borne illness. The park has spent millions working to mouse-proof lodging.YOSEMITE NATIONAL PARK — Sisters Lauren Scott and Patrice Fambrini stood near the check-in desk of Curry Village, a quaint collection of tents and cabins in Yosemite National Park, and considered the merits of their lodgings. (Source: L.A. Times - Health)
Source: L.A. Times - Health - May 26, 2013 Category: Consumer Health News Source Type: news

Yosemite makeover seeks to keep hantavirus at bay
Last year, three visitors died and six became ill when they were infected by the rodent-borne illness. The park has spent millions working to mouse-proof lodging.YOSEMITE NATIONAL PARK — Sisters Lauren Scott and Patrice Fambrini stood near the check-in desk of Curry Village, a quaint collection of tents and cabins in Yosemite National Park, and considered the merits of their lodgings. (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - May 26, 2013 Category: Science Source Type: news

HPA issues guidance for pet rodent owners following recent cases of hantavirus
The Health Protection Agency (HPA) has issued new guidance for owners of pet rodents following two recent UK cases of hantavirus which are described in a paper published in this week’s Eurosurveillance. (Source: Health Protection Agency)
Source: Health Protection Agency - March 1, 2013 Category: UK Health Source Type: news

Paediatricians for a Healthy Environment
A group of Argentine paediatricians has been combining work on environmental protection and child health for more than 10 years. It appears a basic principle to apply, but the task is turning out to be increasingly challenging and complex. “We can’t clean up a river, or give a family a new house, but we can teach people to put chlorine in the water,” Dr. Stella Maris Gil, the coordinator of the Environmental Paediatric Unit (UPA) at the Pedro de Elizalde Children’s Hospital in the Constitución neighbourhood of Buenos Aires, told IPS. The UPA provides health care with a strong environmental co...
Source: IPS Inter Press Service - Health - January 4, 2013 Category: Global & Universal Authors: Marcela Valente Tags: Active Citizens Civil Society Development & Aid Environment Featured Headlines Health Human Rights Latin America & the Caribbean Poverty & MDGs Regional Categories Women's Health Argentina Maternal and Child Health Pollution Source Type: news