Identification and characterization of codon usage pattern and influencing factors in HFRS-causing hantaviruses
This study, although comprehensive, relies on in silico methods and thus necessitates experimental validation for more solid outcomes. Beyond the identified factors influencing viral behavior, there could be other yet undiscovered influences. These potential factors should be targets for further research to improve HFRS therapeutic strategies. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - July 10, 2023 Category: Allergy & Immunology Source Type: research

Viruses, Vol. 15, Pages 1395: Hantavirus in Panama: Twenty Years of Epidemiological Surveillance Experience
González Heydy Nuñez Susana Hesse Fernando Rivera George Edwards Ricardo Chong Ovidio Mendoza Martín Meza Milagro Herrera Rudick Kant Raul Esquivel Dora Estripeaut Demetrio Serracín Bernardino Denis Esthefani Robles Yaxelis Mendoza Gloria Gonzalez Felicia Tulloch Juan Miguel Pascale Jonathan L. Dunnum Joseph A. Cook Anibal G. Armién Fernando Gracia Gladys Alicia Guerrero Itza de Mosca Twenty years have passed since the emergence of hantavirus zoonosis in Panama at the beginning of this millennium. We provide an overview of epidemiological surveillance of hantavirus ...
Source: Viruses - June 19, 2023 Category: Virology Authors: Blas Armi én Carlos Mu ñoz Hector Cede ño Jacqueline R. Salazar Tybbyssay P. Salinas Publio Gonz ález Jos é Trujillo Deyanira S ánchez Jamileth Mari ñas Ayvar Hern ández Harmodio Cruz Leisy Yovany Villarreal Elba Grimaldo Samuel Gonz ález Heydy N Tags: Article Source Type: research

Viruses, Vol. 15, Pages 1390: Two Decades of Wildlife Pathogen Surveillance: Case Study of Choclo orthohantavirus and Its Wild Reservoir Oligoryzomys costaricensis
Armien Joseph A. Cook Blas Armien The Costa Rican pygmy rice rat (Oligoryzomys costaricensis) is the primary reservoir of Choclo orthohantavirus (CHOV), the causal agent of hantavirus disease, pulmonary syndrome, and fever in humans in Panama. Since the emergence of CHOV in early 2000, we have systematically sampled and archived rodents from >150 sites across Panama to establish a baseline understanding of the host and virus, producing a permanent archive of holistic specimens that we are now probing in greater detail. We summarize these collections and explore preliminary habitat/virus associations to ...
Source: Viruses - June 17, 2023 Category: Virology Authors: Publio Gonzalez Jacqueline R. Salazar Tybbysay P. Salinas Mario Avila Jocelyn P. Colella Jonathan L. Dunnum Gregory E. Glass Gloria Gonzalez Enos Juarez Kimberly Lindblade Edwin Pile Yaxelis Mendoza Juan Miguel Pascale Anibal G. Armien Joseph A. Cook Blas Tags: Article Source Type: research

Incidence of Orthohantavirus infection in humans follows observed changes in rodent reservoirs, Hubei Province, China (1984-2010)
In this study, we analyzed the incidence of Orthohantavirus infection in humans and observed changes in rodent reservoirs in Hubei Province.RESULTS: The results indicated that although the incidence of HFRS declined from the 1990s, the human inapparent infection did not decrease dramatically. Although elements of the disease ecology have changed over the study period, Apodemus agrarius and Rattus norvegicus remain the major species and a constituent ratio of Rattus norvegicus increased. Rodent population density fluctuated between 16.65% and 2.14%, and decreased quinquennially, showing an obvious downward trend in recent y...
Source: American Journal of Veterinary Research - June 12, 2023 Category: Veterinary Research Authors: Yuan-Yuan Liu An Yang Ying-Qi Xu Yi-Hui Zhang Cheng-Si Bai Yu-Qing Zhang Xiao-Li Mou Fan Luo Shu-Liang Chen Wei Hou Zhan-Qiu Yang Liang-Jun Chen Hai-Rong Xiong Source Type: research

Incidence of Orthohantavirus infection in humans follows observed changes in rodent reservoirs, Hubei Province, China (1984-2010)
In this study, we analyzed the incidence of Orthohantavirus infection in humans and observed changes in rodent reservoirs in Hubei Province.RESULTS: The results indicated that although the incidence of HFRS declined from the 1990s, the human inapparent infection did not decrease dramatically. Although elements of the disease ecology have changed over the study period, Apodemus agrarius and Rattus norvegicus remain the major species and a constituent ratio of Rattus norvegicus increased. Rodent population density fluctuated between 16.65% and 2.14%, and decreased quinquennially, showing an obvious downward trend in recent y...
Source: American Journal of Veterinary Research - June 12, 2023 Category: Veterinary Research Authors: Yuan-Yuan Liu An Yang Ying-Qi Xu Yi-Hui Zhang Cheng-Si Bai Yu-Qing Zhang Xiao-Li Mou Fan Luo Shu-Liang Chen Wei Hou Zhan-Qiu Yang Liang-Jun Chen Hai-Rong Xiong Source Type: research

Incidence of Orthohantavirus infection in humans follows observed changes in rodent reservoirs, Hubei Province, China (1984-2010)
In this study, we analyzed the incidence of Orthohantavirus infection in humans and observed changes in rodent reservoirs in Hubei Province.RESULTS: The results indicated that although the incidence of HFRS declined from the 1990s, the human inapparent infection did not decrease dramatically. Although elements of the disease ecology have changed over the study period, Apodemus agrarius and Rattus norvegicus remain the major species and a constituent ratio of Rattus norvegicus increased. Rodent population density fluctuated between 16.65% and 2.14%, and decreased quinquennially, showing an obvious downward trend in recent y...
Source: American Journal of Veterinary Research - June 12, 2023 Category: Veterinary Research Authors: Yuan-Yuan Liu An Yang Ying-Qi Xu Yi-Hui Zhang Cheng-Si Bai Yu-Qing Zhang Xiao-Li Mou Fan Luo Shu-Liang Chen Wei Hou Zhan-Qiu Yang Liang-Jun Chen Hai-Rong Xiong Source Type: research

Prevalence and occupational exposure to zoonotic diseases in high-risk populations in the Free State Province, South Africa
This study investigated the prevalence of selected zoonoses in cattle, farm workers and occupational exposure to endemic zoonotic diseases and their associated risk factors.MethodsSputum samples from farmworkers were screened for Mycobacterium bovis. Blood specimens from farmworkers and archived sera were tested for serological evidence of Brucella sp., hantaviruses, and Leptospira sp. Communal and commercial cattle herds were tested for bovine tuberculosis and brucellosis.ResultsMycobacterium bovis was not isolated from human samples. A total of 327 human sera were screened, and 35/327 (10.7%) were Brucella sp. IgG positi...
Source: Frontiers in Microbiology - June 5, 2023 Category: Microbiology Source Type: research

Viruses, Vol. 15, Pages 1313: Multiple Lineages of Hantaviruses Harbored by the Iberian Mole (Talpa occidentalis) in Spain
d Yanagihara The recent detection of both Nova virus (NVAV) and Bruges virus (BRGV) in European moles (Talpa europaea) in Belgium and Germany prompted a search for related hantaviruses in the Iberian mole (Talpa occidentalis). RNAlater®-preserved lung tissue from 106 Iberian moles, collected during January 2011 to June 2014 in Asturias, Spain, were analyzed for hantavirus RNA by nested/hemi-nested RT-PCR. Pairwise alignment and comparison of partial L-segment sequences, detected in 11 Iberian moles from four parishes, indicated the circulation of genetically distinct hantaviruses. Phylogenetic analyses, usi...
Source: Viruses - June 2, 2023 Category: Virology Authors: Se Hun Gu Marcos Mi ñarro Carlos Feliu Jean-Pierre Hugot Naomi L. Forrester Scott C. Weaver Richard Yanagihara Tags: Article Source Type: research

Expansion of hantavirus infection during the SARS-CoV-2 pandemic in Bosnia and Herzegovina, 2021
Conclusion. The reported infections were probably caused by exposure of individuals to at-risk areas inhabited by contaminated rodents as natural reservoirs of hantavirus. As a highly endemic area, B and H requires continuous monitoring and increased awareness of this problem.PMID:37255412 | DOI:10.1099/jmm.0.001687 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 31, 2023 Category: Microbiology Authors: Irma Salimovi ć-Bešić Semir Hrvo Edina Zahirovi ć El-Jesah Đulić Rusmir Balji ć Amela Dedei ć-Ljubović Source Type: research

Expansion of hantavirus infection during the SARS-CoV-2 pandemic in Bosnia and Herzegovina, 2021
Conclusion. The reported infections were probably caused by exposure of individuals to at-risk areas inhabited by contaminated rodents as natural reservoirs of hantavirus. As a highly endemic area, B and H requires continuous monitoring and increased awareness of this problem.PMID:37255412 | DOI:10.1099/jmm.0.001687 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 31, 2023 Category: Microbiology Authors: Irma Salimovi ć-Bešić Semir Hrvo Edina Zahirovi ć El-Jesah Đulić Rusmir Balji ć Amela Dedei ć-Ljubović Source Type: research

Epidemiological profile of Hantavirus in the Ñuble region period 2002-2018, Chile
Braz J Biol. 2023 May 22;84:e269097. doi: 10.1590/1519-6984.269097. eCollection 2023.ABSTRACTHantavirus infection is an endemic zoonosis in Chile, with an average lethality of around 36%. The highest lethality (60%) was recorded in 1997. Prevention strategies have been applied since then. Early diagnosis and technologies, such as the use of ECMO (Extracorporeal Membrane Oxygenation) and Hantavirus immune plasma, have contributed to increasing the survival of people due to this disease at the national level. In the newly created Region of Ñuble in Chile, the incidence and lethality of Hantavirus cases are unknown; therefor...
Source: Braz J Biol - May 24, 2023 Category: Biology Authors: C Dospital P Arancibia-Avila J Araneda-Flores Source Type: research

Epidemiological profile of Hantavirus in the Ñuble region period 2002-2018, Chile
Braz J Biol. 2023 May 22;84:e269097. doi: 10.1590/1519-6984.269097. eCollection 2023.ABSTRACTHantavirus infection is an endemic zoonosis in Chile, with an average lethality of around 36%. The highest lethality (60%) was recorded in 1997. Prevention strategies have been applied since then. Early diagnosis and technologies, such as the use of ECMO (Extracorporeal Membrane Oxygenation) and Hantavirus immune plasma, have contributed to increasing the survival of people due to this disease at the national level. In the newly created Region of Ñuble in Chile, the incidence and lethality of Hantavirus cases are unknown; therefor...
Source: Braz J Biol - May 24, 2023 Category: Biology Authors: C Dospital P Arancibia-Avila J Araneda-Flores Source Type: research

Epidemiological profile of Hantavirus in the Ñuble region period 2002-2018, Chile
Braz J Biol. 2023 May 22;84:e269097. doi: 10.1590/1519-6984.269097. eCollection 2023.ABSTRACTHantavirus infection is an endemic zoonosis in Chile, with an average lethality of around 36%. The highest lethality (60%) was recorded in 1997. Prevention strategies have been applied since then. Early diagnosis and technologies, such as the use of ECMO (Extracorporeal Membrane Oxygenation) and Hantavirus immune plasma, have contributed to increasing the survival of people due to this disease at the national level. In the newly created Region of Ñuble in Chile, the incidence and lethality of Hantavirus cases are unknown; therefor...
Source: Braz J Biol - May 24, 2023 Category: Biology Authors: C Dospital P Arancibia-Avila J Araneda-Flores Source Type: research

Epidemiological profile of Hantavirus in the Ñuble region period 2002-2018, Chile
Braz J Biol. 2023 May 22;84:e269097. doi: 10.1590/1519-6984.269097. eCollection 2023.ABSTRACTHantavirus infection is an endemic zoonosis in Chile, with an average lethality of around 36%. The highest lethality (60%) was recorded in 1997. Prevention strategies have been applied since then. Early diagnosis and technologies, such as the use of ECMO (Extracorporeal Membrane Oxygenation) and Hantavirus immune plasma, have contributed to increasing the survival of people due to this disease at the national level. In the newly created Region of Ñuble in Chile, the incidence and lethality of Hantavirus cases are unknown; therefor...
Source: Braz J Biol - May 24, 2023 Category: Biology Authors: C Dospital P Arancibia-Avila J Araneda-Flores Source Type: research

Epidemiological profile of Hantavirus in the Ñuble region period 2002-2018, Chile
Braz J Biol. 2023 May 22;84:e269097. doi: 10.1590/1519-6984.269097. eCollection 2023.ABSTRACTHantavirus infection is an endemic zoonosis in Chile, with an average lethality of around 36%. The highest lethality (60%) was recorded in 1997. Prevention strategies have been applied since then. Early diagnosis and technologies, such as the use of ECMO (Extracorporeal Membrane Oxygenation) and Hantavirus immune plasma, have contributed to increasing the survival of people due to this disease at the national level. In the newly created Region of Ñuble in Chile, the incidence and lethality of Hantavirus cases are unknown; therefor...
Source: Braz J Biol - May 24, 2023 Category: Biology Authors: C Dospital P Arancibia-Avila J Araneda-Flores Source Type: research