Gelatin/poly(vinyl alcohol)-based functional films integrated with spent coffee ground-derived carbon dots and grapefruit seed extract for active packaging application
Int J Biol Macromol. 2023 Jan 30:123493. doi: 10.1016/j.ijbiomac.2023.123493. Online ahead of print.ABSTRACTNanoparticles are attractive, functional additives with great potential to be applied in biomaterial and food packaging. However, these particles are not soluble in water, thus limiting their widespread application. Here, we report a facile fabrication of carbon dots (CDs) using the spent coffee ground as the carbon source through a hydrothermal method. The CD was added to the gelatin/poly(vinyl alcohol) (Gel/PVA) film and grapefruit seed extract (GSE) to prepare multifunctional packaging films. The functional films'...
Source: International Journal of Biological Macromolecules - February 2, 2023 Category: Biochemistry Authors: Seungjae Min Parya Ezati Ki Sun Yoon Jong-Whan Rhim Source Type: research
Gelatin/poly(vinyl alcohol)-based functional films integrated with spent coffee ground-derived carbon dots and grapefruit seed extract for active packaging application
Int J Biol Macromol. 2023 Jan 30:123493. doi: 10.1016/j.ijbiomac.2023.123493. Online ahead of print.ABSTRACTNanoparticles are attractive, functional additives with great potential to be applied in biomaterial and food packaging. However, these particles are not soluble in water, thus limiting their widespread application. Here, we report a facile fabrication of carbon dots (CDs) using the spent coffee ground as the carbon source through a hydrothermal method. The CD was added to the gelatin/poly(vinyl alcohol) (Gel/PVA) film and grapefruit seed extract (GSE) to prepare multifunctional packaging films. The functional films'...
Source: International Journal of Biological Macromolecules - February 2, 2023 Category: Biochemistry Authors: Seungjae Min Parya Ezati Ki Sun Yoon Jong-Whan Rhim Source Type: research
Narirutin. A flavonoid found in citrus fruits modulates cell cycle phases and inhibits the proliferation of hormone-refractory prostate cancer cells by targeting hyaluronidase
Food Chem Toxicol. 2023 Jan 25:113638. doi: 10.1016/j.fct.2023.113638. Online ahead of print.ABSTRACTNarirutin is a dietary flavanone found in lemons, oranges, passion fruit, bergamot and grapefruit. It possesses anti-allergic, cardioprotective, neuroprotective, hepatoprotective potential, and its enriched fraction suppresses the growth of prostate cancer cells; however, there is currently no information on the chemopreventive potential of narirutin alone against hormone-refractory prostate cancer cells (PC-3) and its mode of action. Thus, the chemopreventive possibility of narirutin was investigated in PC-3 cells by utili...
Source: Food and Chemical Toxicology - January 28, 2023 Category: Food Science Authors: Shilpi Singh Akhilesh Kumar Maurya Abha Meena Nidhi Mishra Suaib Luqman Source Type: research
Narirutin. A flavonoid found in citrus fruits modulates cell cycle phases and inhibits the proliferation of hormone-refractory prostate cancer cells by targeting hyaluronidase
Food Chem Toxicol. 2023 Jan 25:113638. doi: 10.1016/j.fct.2023.113638. Online ahead of print.ABSTRACTNarirutin is a dietary flavanone found in lemons, oranges, passion fruit, bergamot and grapefruit. It possesses anti-allergic, cardioprotective, neuroprotective, hepatoprotective potential, and its enriched fraction suppresses the growth of prostate cancer cells; however, there is currently no information on the chemopreventive potential of narirutin alone against hormone-refractory prostate cancer cells (PC-3) and its mode of action. Thus, the chemopreventive possibility of narirutin was investigated in PC-3 cells by utili...
Source: Cell Research - January 28, 2023 Category: Cytology Authors: Shilpi Singh Akhilesh Kumar Maurya Abha Meena Nidhi Mishra Suaib Luqman Source Type: research
Interactions between natural products and cancer treatments: underlying mechanisms and clinical importance
AbstractNatural products, also referred to as dietary supplements, complementary and alternative medicines, and health or food supplements are widely used by people living with cancer. These products are predominantly self-selected and taken concurrently with cancer treatments with the intention of improving quality of life, immune function and reducing cancer symptoms and treatment side effects. Concerns have been raised that concurrent use may lead to interactions resulting in adverse effects and unintended treatment outcomes. This review provides an overview of the mechanisms by which these interactions can occur and th...
Source: Cancer Chemotherapy and Pharmacology - January 27, 2023 Category: Cancer & Oncology Source Type: research
An Overview of Biosynthetic Pathway and Therapeutic Potential of Rutin
Mini Rev Med Chem. 2023 Jan 25. doi: 10.2174/1389557523666230125104101. Online ahead of print.ABSTRACTFlavonoids are compounds abundantly found in nature and known as a polyphenolic group of compounds having flavancore and show the utmost abundant collection of complexes and are found in fiber-rich root vegetables, fruits, and their eatable items. Due to the presence of hydroxyl groups, flavonoids show various therapeutic activities like antioxidant, antibacterial, antiviral, and anti-inflammatory. Substituent groups are responsible for the onset of biochemical actions of flavonoids, which affect the metabolism. The major ...
Source: Mini Reviews in Medicinal Chemistry - January 26, 2023 Category: Chemistry Authors: Jugnu Goyal Prabhakar Kumar Verma Source Type: research
An Overview of Biosynthetic Pathway and Therapeutic Potential of Rutin
Mini Rev Med Chem. 2023 Jan 25. doi: 10.2174/1389557523666230125104101. Online ahead of print.ABSTRACTFlavonoids are compounds abundantly found in nature and known as a polyphenolic group of compounds having flavancore and show the utmost abundant collection of complexes and are found in fiber-rich root vegetables, fruits, and their eatable items. Due to the presence of hydroxyl groups, flavonoids show various therapeutic activities like antioxidant, antibacterial, antiviral, and anti-inflammatory. Substituent groups are responsible for the onset of biochemical actions of flavonoids, which affect the metabolism. The major ...
Source: Mini Reviews in Medicinal Chemistry - January 26, 2023 Category: Chemistry Authors: Jugnu Goyal Prabhakar Kumar Verma Source Type: research
Gaining new insights into macroplastic transport 'hotlines' and fine-scale retention-remobilisation using small floating high-resolution satellite drifters in the Chao Phraya River estuary of Bangkok
This study indicates that river macroplastic debris transport 'hotlines' (positions where floating debris will likely pass by in a river) as well as retention-remobilisation cycles can be studied at fine scale. On their way through the river and gulf, covering between 9 and 600 km, drifters got stuck up to ten times, spending 80% of their lifetime in retention. Furthermore, it is outlined that the trajectories can be linked with environmental factors such as bathymetry and tides to more accurately model macroplastic debris behaviour in rivers. Finally, it is shown that trajectories crossing the riverine-marine continuum at...
Source: Environmental Pollution - January 22, 2023 Category: Environmental Health Authors: Thomas Mani Yotwadee Hawangchu Pummarin Khamdahsag Jenyuk Lohwacharin Doungkamon Phihusut Isara Arsiranant Chalatip Junchompoo Ratchanon Piemjaiswang Source Type: research
Content analysis and drug safety evaluation of four furanocoumarins in six pomelos produced in China
Nat Prod Res. 2023 Jan 19:1-10. doi: 10.1080/14786419.2023.2167203. Online ahead of print.ABSTRACTThe content of 4 6',7'-dihydroxybergamottin (DHB), bergamottin, isoimperatorin and epoxybergamottin of six pomelos produced in China were detected by High-performance liquid chromatography-diode array detection and their safety of related medicines was evaluated by inhibition of medium concentration (IC50) of cytochrome oxidases CYP450-like. The results showed that the total content of the four furanocoumarins in these pomelo juices from high to low in order was Guanximi pomelo > Liangping pomelo > Pinghemi pomelo > g...
Source: Natural Product Research - January 19, 2023 Category: Biochemistry Authors: Weiling Chen Zeqi Li Yujiao Cheng Guijie Li Jiaqi Li Linhua Huang Qiuming Gu Houjiu Wu Source Type: research
Molecules, Vol. 28, Pages 730: Grapefruit Seed Extract-Added Functional Films and Coating for Active Packaging Applications: A Review
Whan Rhim
Recently, consumers have been increasingly inclined towards natural antimicrobials and antioxidants in food processing and packaging. Several bioactive compounds have originated from natural sources, and among them, grapefruit seed extract (GSE) is widely accepted and generally safe to use in food. GSE is a very commonly used antimicrobial in food; lately, it has also been found very effective as a coating material or in edible packaging films. A lot of recent work reports the use of GSE in food packaging applications to ensure food quality and safety; therefore, this work intended to provide an up-to-date re...
Source: Molecules - January 11, 2023 Category: Chemistry Authors: Swarup Roy Wanli Zhang Deblina Biswas Rejish Ramakrishnan Jong-Whan Rhim Tags: Review Source Type: research
Molecular and biological characterization of a novel citrus tristeza virus isolate that causes severe symptoms in Citrus junos cv. Ziyangxiangcheng
AbstractThe complete genomic sequence of a novel citrus tristeza virus (CTV) isolate, CT91-A1, from Orah tangor grafted onCitrus junos cv. Ziyangxiangcheng rootstock in China was determined by transcriptome sequencing. Sequence alignments showed that isolate CT91-A1 shared 83.3 to 95.5% nucleotide sequence identity with extant CTV genotypes at the whole-genome level, with the highest similarity to the S1 genotype. Phylogenetic analysis revealed that CT91-A1 clustered in a unique subclade with the S1 genotype. Isolate CT91-A1 induced severe stem pitting in Mexican lime andC. junos cv. Ziyangxiangcheng and moderate stem pitt...
Source: Archives of Virology - January 9, 2023 Category: Virology Source Type: research
Molecules, Vol. 28, Pages 269: Nomilin and Its Analogues in Citrus Fruits: A Review of Its Health Promotion Effects and Potential Application in Medicine
hengjie Fan
Nomilin is one of the major limonoids, which are plant secondary metabolites also known as tetranortriterpenoids. Nomilin is found mostly in common edible citrus fruits including lemons, limes, oranges, grapefruits, mandarins, along with traditional Chinese medicines derived from citrus fruits, such as tangerine seed, tangerine peel, fructus aurantii immaturus, etc. A number of studies have demonstrated that nomilin and its analogues exhibit a variety of biological and pharmacological activities. These include anti-cancer, immune-modulatory, anti-inflammatory, anti-obesity, anti-viral, anti-osteoclastogenic...
Source: Molecules - December 29, 2022 Category: Chemistry Authors: Zhenyu Zhou Yingxuan Yan Hongli Li Yaru Feng Cheng Huang Shengjie Fan Tags: Review Source Type: research
Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer's disease-like behavioral rat model
Neurotoxicology. 2022 Dec 19:S0161-813X(22)00200-5. doi: 10.1016/j.neuro.2022.12.007. Online ahead of print.ABSTRACTAlzheimer's disease (AD), as the most typical type of dementia, is a chronic neurodegenerative disorder characterized by progressive learning and memory impairment. It is known that the main causes of AD are the accumulation of β-amyloid (Aβ) plaques and neurofibrillary tangles (NFT) containing hyperphosphorylated tau protein. Naringin is a flavonoid from citrus fruits, especially in grapefruit, which has anti-inflammatory, antioxidant, anti-apoptotic, and neuroprotective activities. However, the effect of ...
Source: Neurotoxicology - December 22, 2022 Category: Neurology Authors: Ga-Young Choi Hyun-Bum Kim Eun-Sang Hwang Ho-Sub Park Jae-Min Cho Ham Young-Ki Jin-Hee Kim Mi-Kyung Mun Sungho Maeng Ji-Ho Park Source Type: research
Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer's disease-like behavioral rat model
Neurotoxicology. 2022 Dec 19:S0161-813X(22)00200-5. doi: 10.1016/j.neuro.2022.12.007. Online ahead of print.ABSTRACTAlzheimer's disease (AD), as the most typical type of dementia, is a chronic neurodegenerative disorder characterized by progressive learning and memory impairment. It is known that the main causes of AD are the accumulation of β-amyloid (Aβ) plaques and neurofibrillary tangles (NFT) containing hyperphosphorylated tau protein. Naringin is a flavonoid from citrus fruits, especially in grapefruit, which has anti-inflammatory, antioxidant, anti-apoptotic, and neuroprotective activities. However, the effect of ...
Source: Neurotoxicology - December 22, 2022 Category: Neurology Authors: Ga-Young Choi Hyun-Bum Kim Eun-Sang Hwang Ho-Sub Park Jae-Min Cho Ham Young-Ki Jin-Hee Kim Mi-Kyung Mun Sungho Maeng Ji-Ho Park Source Type: research
