Naringin alleviates liver damage induced by D-galactosamine (D-gal) in mice through down-regulation of CYP2E1 and P53 hyperactivity
This study aims to study the potential antioxidants and the anti-inflammatory effects of naringin in mice-induced liver damage by D-galactosamine (D-gal) administration. Mice were divided into four groups: group 1, the normal control group; group 2, the D-gal group was injected (200 mg /kg; s.c.) daily for 8 weeks; and groups 3 and 4, naringin groups received naringin (150 mg/kg and 300 mg/kg; p.o.) daily concurrent with D-gal for 8 weeks. Serum was prepared to measure aspartate transaminase (AST) and alanine transaminases (ALT). Liver tissue homogenate was prepared to me asure nitric oxide (NO), catalase, cytochrome...
Source: Comparative Clinical Pathology - February 28, 2024 Category: Pathology Source Type: research
Development of Simplified Recombinase Polymerase Amplification Assay for Rapid and Robust Detection of Citrus Yellow Vein Clearing Virus
Curr Microbiol. 2024 Feb 22;81(4):103. doi: 10.1007/s00284-024-03614-y.ABSTRACTCitrus is an economically important fruit crop, belongs to family Rutaceae, cultivated commercially in over 130 countries, which holds a leading profitable position in the international market. The most important citrus varieties are mandarins, oranges, lemons, sweet limes, grapefruits and pomelos. Citrus yellow vein clearing virus (CYVCV) is an important graft transmissible plant pathogen known to reduce productivity of citrus fruits due to its predominant association and widespread occurrence. Requirement of fast, reliable, efficient & eco...
Source: Current Microbiology - February 22, 2024 Category: Microbiology Authors: Nitika Gupta Rakesh Kumar Gopi Kishan Susheel Kumar Sharma Nishant Srivastava Ashwini Kumar Virendra Kumar Baranwal Source Type: research
A fluorescent DNAzyme-based biosensor for the detection of lead ions using carbon quantum dots prepared from grapefruit peel
New J. Chem., 2024, Advance Article DOI: 10.1039/D3NJ05829H, PaperWeiqin Zhao, Chun Huang, Youyu Zhu, Yuangang Li, Yingfeng Duan, Jie Gao The key design strategy lies in hemin/G-CQDs. The fluorescence of G-CQDs was quenched after binding with hemin and recovered after removing hemin by combining with a G-quadruplex. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - February 14, 2024 Category: Chemistry Authors: Weiqin Zhao Source Type: research
GC-MS Analysis and Study of the Antimicrobial Activity of < em > Citrus paradisi < /em > , < em > Citrus aurantifolia < /em > , and < em > Citrus sinensis < /em > Peel Essential Oils as Hand Sanitizer
In conclusion, essential oils obtained from citrus fruit peel represent a rich source of compounds possessing antimicrobial properties and could be an alternative to synthetic antimicrobial agents.PMID:38204865 | PMC:PMC10776194 | DOI:10.1155/2024/4957712 (Source: International Journal of Microbiology)
Source: International Journal of Microbiology - January 11, 2024 Category: Microbiology Authors: Isra Osman Mohammed Ayat Ahmed Alrasheid Saad Mohammed Hussein Ayoub Source Type: research
Magnitude of Fruit Juice-Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices
Biol Pharm Bull. 2024;47(1):72-78. doi: 10.1248/bpb.b23-00490.ABSTRACTWe recently reported that the gastrointestinal (GI) fluid volume is influenced by the solution osmolality, and proposed that this effect may play a role in beverage-drug interactions. Here, we investigated whether osmolality-dependent fluid secretion can explain the difference in the magnitudes of fruit juice-drug interactions depending on the type of fruit juice (grapefruit juice (GFJ), orange juice (OJ), and apple juice (AJ)). The osmolality of GFJ, OJ, and AJ used in this study was found to be 552, 686, and 749 mOsm/kg, respectively. Measurements of i...
Source: Biological and Pharmaceutical Bulletin - January 3, 2024 Category: Drugs & Pharmacology Authors: Miyuki Takemura Katsuhisa Inoue Ikumi Tamai Yoshiyuki Shirasaka Source Type: research
Magnitude of Fruit Juice-Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices
Biol Pharm Bull. 2024;47(1):72-78. doi: 10.1248/bpb.b23-00490.ABSTRACTWe recently reported that the gastrointestinal (GI) fluid volume is influenced by the solution osmolality, and proposed that this effect may play a role in beverage-drug interactions. Here, we investigated whether osmolality-dependent fluid secretion can explain the difference in the magnitudes of fruit juice-drug interactions depending on the type of fruit juice (grapefruit juice (GFJ), orange juice (OJ), and apple juice (AJ)). The osmolality of GFJ, OJ, and AJ used in this study was found to be 552, 686, and 749 mOsm/kg, respectively. Measurements of i...
Source: Biological and Pharmaceutical Bulletin - January 3, 2024 Category: Drugs & Pharmacology Authors: Miyuki Takemura Katsuhisa Inoue Ikumi Tamai Yoshiyuki Shirasaka Source Type: research
Magnitude of Fruit Juice-Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices
Biol Pharm Bull. 2024;47(1):72-78. doi: 10.1248/bpb.b23-00490.ABSTRACTWe recently reported that the gastrointestinal (GI) fluid volume is influenced by the solution osmolality, and proposed that this effect may play a role in beverage-drug interactions. Here, we investigated whether osmolality-dependent fluid secretion can explain the difference in the magnitudes of fruit juice-drug interactions depending on the type of fruit juice (grapefruit juice (GFJ), orange juice (OJ), and apple juice (AJ)). The osmolality of GFJ, OJ, and AJ used in this study was found to be 552, 686, and 749 mOsm/kg, respectively. Measurements of i...
Source: Biological and Pharmaceutical Bulletin - January 3, 2024 Category: Drugs & Pharmacology Authors: Miyuki Takemura Katsuhisa Inoue Ikumi Tamai Yoshiyuki Shirasaka Source Type: research
Magnitude of Fruit Juice-Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices
Biol Pharm Bull. 2024;47(1):72-78. doi: 10.1248/bpb.b23-00490.ABSTRACTWe recently reported that the gastrointestinal (GI) fluid volume is influenced by the solution osmolality, and proposed that this effect may play a role in beverage-drug interactions. Here, we investigated whether osmolality-dependent fluid secretion can explain the difference in the magnitudes of fruit juice-drug interactions depending on the type of fruit juice (grapefruit juice (GFJ), orange juice (OJ), and apple juice (AJ)). The osmolality of GFJ, OJ, and AJ used in this study was found to be 552, 686, and 749 mOsm/kg, respectively. Measurements of i...
Source: Biological and Pharmaceutical Bulletin - January 3, 2024 Category: Drugs & Pharmacology Authors: Miyuki Takemura Katsuhisa Inoue Ikumi Tamai Yoshiyuki Shirasaka Source Type: research
Magnitude of Fruit Juice-Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices
Biol Pharm Bull. 2024;47(1):72-78. doi: 10.1248/bpb.b23-00490.ABSTRACTWe recently reported that the gastrointestinal (GI) fluid volume is influenced by the solution osmolality, and proposed that this effect may play a role in beverage-drug interactions. Here, we investigated whether osmolality-dependent fluid secretion can explain the difference in the magnitudes of fruit juice-drug interactions depending on the type of fruit juice (grapefruit juice (GFJ), orange juice (OJ), and apple juice (AJ)). The osmolality of GFJ, OJ, and AJ used in this study was found to be 552, 686, and 749 mOsm/kg, respectively. Measurements of i...
Source: Biological and Pharmaceutical Bulletin - January 3, 2024 Category: Drugs & Pharmacology Authors: Miyuki Takemura Katsuhisa Inoue Ikumi Tamai Yoshiyuki Shirasaka Source Type: research
The role of kaempferol in gynaecological malignancies: progress and perspectives
Kaempferol, a flavonoid derived from various herbs such as cocoyam, propolis, and grapefruit, has garnered interest due to its numerous pharmacological benefits, including anti-inflammatory, antioxidant, and anti-diabetic properties. Kaempferol has been shown to possess notable anti-tumour bioactivity, indicating potential for treating gynaecological malignancies. To date, numerous studies have demonstrated the potential of kaempferol to induce tumour cell apoptosis, inhibit proliferation, and prevent metastasis and invasion in several gynaecological malignancies, including breast, ovarian and endometrial cancers. However,...
Source: Frontiers in Pharmacology - December 4, 2023 Category: Drugs & Pharmacology Source Type: research
Citrin allergy is rare but perplexing
In the setting of reported reactions to citrus seed and pectin in patients with cashew allergy, Konstantinou et al1 sought to determine whether they could identify homologous antigens in citrus seeds, pectin, and cashews. As described in their article “Citrin: a novel food allergen in citrus seeds and citrus-derived pectin that shows cross-reactivity with cashew and pistachio,” they used gel electrophoresis, Western blots, and tandem mass spectrometry to identify citrin, an 11S globulin seed storage protein in the cupin superfamily, as a comm on denominator in lemon, orange and grapefruit seeds, grapefruit pectin, and ...
Source: Annals of Allergy, Asthma and Immunology - December 1, 2023 Category: Allergy & Immunology Authors: Elizabeth Gilje, Maureen Bauer Tags: Editorial Source Type: research
Extraction of pectins from renewable grapefruit (Citrus paradisi) peels using deep eutectic solvents and analysis of their structural and physicochemical properties
This study presents an innovative attempt to extract high-quality pectins from grapefruit (Citrus paradisi) peels by using deep eutectic solvents (DESs) as extraction agents. The maximum yield of betaine-citric acid (BC)-extracted pectin (BC-P) reached 36.47 % under the optimum process conditions: an L/S ratio of 25 mL/g, a pH of 2.0, and a temperature of 85 °C for 120 min. The yield of BC-P was significantly higher than HCl-extracted pectin (HCl-P, 8.76 %) under a pH of 2.0. In addition, the structural, physicochemical, and emulsifying properties of the purified pectins (BC-P and HCl-P) and commercial pectin (CP) were co...
Source: International Journal of Biological Macromolecules - November 6, 2023 Category: Biochemistry Authors: Xue Lin Yuezhe Liu Ruimin Wang Jincheng Dai Lu Wang Jiachao Zhang Source Type: research
Efficient rhodamine B dye degradation by red mud-grapefruit peel biochar catalysts activated persulfate in water
This study aimed to raise a new insight to the resource utilization of RM and the control of dye pollution.PMID:37919501 | DOI:10.1007/s11356-023-30537-1 (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - November 3, 2023 Category: Environmental Health Authors: Shuman Deng Maolin Yang Qiang An Zheng Li Bin Zhao Binbin Ran Source Type: research
Composite optimization and characterization of dietary fiber-based edible packaging film reinforced by nanocellulose from grapefruit peel pomace
In this study, the first successful development of an edible packaging film based on dietary fiber using grapefruit soluble dietary fiber (GSDF) from grapefruit peel pomace as a substrate and nanocellulose (GNCC) as a filler was developed. Principal component analysis, membership function synthesis, and response surface methods were used to determine the optimal process to prepare the edible packaging films, and the impact of GNCC on this material was analyzed. The results showed that the overall performance score of the edible packaging film with 1 wt% GNCC was 0.764. The maximum pyrolysis temperature increased from 226.3...
Source: International Journal of Biological Macromolecules - October 26, 2023 Category: Biochemistry Authors: Lili Chen Xinjia Jiang Yanmei Sun Diansong Gan Wenliang Liu Yincai Wu Xihai Hao Source Type: research
Composite optimization and characterization of dietary fiber-based edible packaging film reinforced by nanocellulose from grapefruit peel pomace
In this study, the first successful development of an edible packaging film based on dietary fiber using grapefruit soluble dietary fiber (GSDF) from grapefruit peel pomace as a substrate and nanocellulose (GNCC) as a filler was developed. Principal component analysis, membership function synthesis, and response surface methods were used to determine the optimal process to prepare the edible packaging films, and the impact of GNCC on this material was analyzed. The results showed that the overall performance score of the edible packaging film with 1 wt% GNCC was 0.764. The maximum pyrolysis temperature increased from 226.3...
Source: International Journal of Biological Macromolecules - October 26, 2023 Category: Biochemistry Authors: Lili Chen Xinjia Jiang Yanmei Sun Diansong Gan Wenliang Liu Yincai Wu Xihai Hao Source Type: research
