Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer's disease-like behavioral rat model
Neurotoxicology. 2022 Dec 19:S0161-813X(22)00200-5. doi: 10.1016/j.neuro.2022.12.007. Online ahead of print.ABSTRACTAlzheimer's disease (AD), as the most typical type of dementia, is a chronic neurodegenerative disorder characterized by progressive learning and memory impairment. It is known that the main causes of AD are the accumulation of β-amyloid (Aβ) plaques and neurofibrillary tangles (NFT) containing hyperphosphorylated tau protein. Naringin is a flavonoid from citrus fruits, especially in grapefruit, which has anti-inflammatory, antioxidant, anti-apoptotic, and neuroprotective activities. However, the effect of ...
Source: Neurotoxicology - December 22, 2022 Category: Neurology Authors: Ga-Young Choi Hyun-Bum Kim Eun-Sang Hwang Ho-Sub Park Jae-Min Cho Ham Young-Ki Jin-Hee Kim Mi-Kyung Mun Sungho Maeng Ji-Ho Park Source Type: research
Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer's disease-like behavioral rat model
Neurotoxicology. 2022 Dec 19:S0161-813X(22)00200-5. doi: 10.1016/j.neuro.2022.12.007. Online ahead of print.ABSTRACTAlzheimer's disease (AD), as the most typical type of dementia, is a chronic neurodegenerative disorder characterized by progressive learning and memory impairment. It is known that the main causes of AD are the accumulation of β-amyloid (Aβ) plaques and neurofibrillary tangles (NFT) containing hyperphosphorylated tau protein. Naringin is a flavonoid from citrus fruits, especially in grapefruit, which has anti-inflammatory, antioxidant, anti-apoptotic, and neuroprotective activities. However, the effect of ...
Source: Neurotoxicology - December 22, 2022 Category: Neurology Authors: Ga-Young Choi Hyun-Bum Kim Eun-Sang Hwang Ho-Sub Park Jae-Min Cho Ham Young-Ki Jin-Hee Kim Mi-Kyung Mun Sungho Maeng Ji-Ho Park Source Type: research
Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer's disease-like behavioral rat model
Neurotoxicology. 2022 Dec 19:S0161-813X(22)00200-5. doi: 10.1016/j.neuro.2022.12.007. Online ahead of print.ABSTRACTAlzheimer's disease (AD), as the most typical type of dementia, is a chronic neurodegenerative disorder characterized by progressive learning and memory impairment. It is known that the main causes of AD are the accumulation of β-amyloid (Aβ) plaques and neurofibrillary tangles (NFT) containing hyperphosphorylated tau protein. Naringin is a flavonoid from citrus fruits, especially in grapefruit, which has anti-inflammatory, antioxidant, anti-apoptotic, and neuroprotective activities. However, the effect of ...
Source: Neurotoxicology - December 22, 2022 Category: Neurology Authors: Ga-Young Choi Hyun-Bum Kim Eun-Sang Hwang Ho-Sub Park Jae-Min Cho Ham Young-Ki Jin-Hee Kim Mi-Kyung Mun Sungho Maeng Ji-Ho Park Source Type: research
Molecules, Vol. 27, Pages 8763: Naringinase Biosynthesis by Aspergillus niger on an Optimized Medium Containing Red Grapefruit Albedo
This study aimed to develop a method of naringinase biosynthesis by Aspergillus niger KMS on an optimized culture medium. The concentration of the six medium components in shake flasks was optimized by the Box and Wilson factor gradient method. Naringinase’s substrate, naringin, powdered albedo, flavedo, and red grapefruit segment membranes were used to stimulate naringinase biosynthesis. Rhamnose was chosen as the carbon source, while the nitrogen source was yeast extract and sodium nitrate. Naringinase biosynthesis was most favorable in the culture medium with the following composition (g 100 mL): 3.332&...
Source: Molecules - December 10, 2022 Category: Chemistry Authors: Joanna Bodakowska-Boczniewicz Zbigniew Garncarek Tags: Article Source Type: research
[ASAP] Identification of Key Process Parameters on the Catalytic Fast Pyrolysis of Rio Red Grapefruit Waste to Value-Added Products
Industrial& Engineering Chemistry ResearchDOI: 10.1021/acs.iecr.2c02919 (Source: Industrial and Engineering Chemical Research)
Source: Industrial and Engineering Chemical Research - December 7, 2022 Category: Chemistry Authors: Shreesh Kulkarni, Ankit Verma, David R. Corbin, Mark B. Shiflett, and Patrick L. Mills Source Type: research
Molecules, Vol. 27, Pages 8507: Recovery of Naringin-Rich Flavonoid Extracts from Agroresidues with Anxiolytic- and Antidepressant-like Effects in Mice
rada-Reyes
Citrus paradisi species belong to the Rutaceae family, and it is commonly known as grapefruit. Grapefruit consumption involves a large amount of waste that goes to landfills and produces significant pollution affecting the human health. To examine this phenomenon, we designed an efficient chemical method that recovers naringin-rich flavonoid extracts from the fresh waste of grapefruits, by using the solvent impregnation resin method (SIR) with XAD-4 amberlite and either methanol or water as elution systems. Additionally, we focused on evaluating these extracts’ anxiolytic- and antidepressant-li...
Source: Molecules - December 3, 2022 Category: Chemistry Authors: Liliana Hern ández-Vázquez Julia Cassani Ivo Heyerdahl-Viau Rubria M. Mart ínez-Casares H éctor Luna Ana Mar ía Dorantes-Barrón Daniel Arrieta-B áez Rosa Estrada-Reyes Tags: Article Source Type: research
Chitosan nano-biopolymer/Citrus paradisi peel oil delivery system enhanced shelf-life and postharvest quality of cherry tomato
Int J Biol Macromol. 2022 Nov 22:S0141-8130(22)02741-6. doi: 10.1016/j.ijbiomac.2022.11.182. Online ahead of print.ABSTRACTGrapefruit peel essential oil (CpEO) was loaded on chitosan (Cs) nano-biopolymer by ionic gelation method and its effect on physicochemical properties of cherry tomatoes was evaluated during 18 days of storage at 10 °C. The highest loading capacity and encapsulation efficiency were obtained from the weight ratio of 1:0.25 Cs to oil. TEM, DLS and FTIR were used to characterize the nanoparticles. The release of the oil from the nanoparticles followed the Fickian diffusion model. CpEO-CsNPs-CO and CpEO-C...
Source: International Journal of Biological Macromolecules - November 25, 2022 Category: Biochemistry Authors: Rahimeh Jahani Mahdi Behnamian Sara Dezhsetan Roghayeh Karimirad Esmaeil Chamani Source Type: research
Chitosan nano-biopolymer/Citrus paradisi peel oil delivery system enhanced shelf-life and postharvest quality of cherry tomato
Int J Biol Macromol. 2022 Nov 22:S0141-8130(22)02741-6. doi: 10.1016/j.ijbiomac.2022.11.182. Online ahead of print.ABSTRACTGrapefruit peel essential oil (CpEO) was loaded on chitosan (Cs) nano-biopolymer by ionic gelation method and its effect on physicochemical properties of cherry tomatoes was evaluated during 18 days of storage at 10 °C. The highest loading capacity and encapsulation efficiency were obtained from the weight ratio of 1:0.25 Cs to oil. TEM, DLS and FTIR were used to characterize the nanoparticles. The release of the oil from the nanoparticles followed the Fickian diffusion model. CpEO-CsNPs-CO and CpEO-C...
Source: International Journal of Biological Macromolecules - November 25, 2022 Category: Biochemistry Authors: Rahimeh Jahani Mahdi Behnamian Sara Dezhsetan Roghayeh Karimirad Esmaeil Chamani Source Type: research
IJERPH, Vol. 19, Pages 15650: Enhanced Adsorption of Cd on Iron & ndash;Organic Associations Formed by Laccase-Mediated Modification: Implications for the Immobilization of Cadmium in Paddy Soil
The objectives of this study were to evaluate the cadmium adsorption capacity of iron–organic associations (Fe-OM) formed by laccase-mediated modification and assess the effect of Fe-OM on the immobilization of cadmium in paddy soil. Leaf organic matter (OM) was extracted from Changshan grapefruit leaves, and then dissolved organic matter (Lac-OM) and precipitated organic matter (Lac-P) were obtained by laccase catalytic modification. Different Fe-OM associations were obtained by co-precipitation of Fe with OM, Lac-OM, and Lac-P, respectively, and the adsorption kinetics, adsorption edge, and isothermal adsor...
Source: International Journal of Environmental Research and Public Health - November 25, 2022 Category: Environmental Health Authors: Weilin Yang Chunlei Huang Xiang Wan Yunyun Zhao Zhengyu Bao Wu Xiang Tags: Article Source Type: research
Molecules, Vol. 27, Pages 7044: The Chemical Composition and Antibacterial and Antioxidant Activities of Five Citrus Essential Oils
Yanling Li
Increasing concerns over the use of antimicrobial growth promoters in animal production has prompted the need to explore the use of natural alternatives such as phytogenic compounds and probiotics. Citrus EOs have the potential to be used as an alternative to antibiotics in animals. The purpose of this research was to study the antibacterial and antioxidant activities of five citrus EOs, grapefruit essential oil (GEO), sweet orange EO (SEO), bergamot EO (BEO), lemon EO (LEO) and their active component d-limonene EO (DLEO). The chemical composition of EOs was analyzed by gas chromatography–ma...
Source: Molecules - October 19, 2022 Category: Chemistry Authors: Yan Li Shutian Liu Chen Zhao Zhuo Zhang Dechao Nie Weixuan Tang Yanling Li Tags: Article Source Type: research
Coping with global warming: Adult thermal thresholds in four pestiferous Anastrepha species determined under experimental laboratory conditions and development/survival times of immatures and adults under natural field conditions
Climate change, particularly global warming, is disturbing biological processes in unexpected ways and forcing us to re-study/reanalyze the effects of varying temperatures, among them extreme ones, on insect functional traits such as lifespan and fecundity/fertility. Here we experimentally tested, under both laboratory and field conditions, the effects of an extreme range of temperatures (5, 10, 15, 20, 30, 40, and 45 °C, and the naturally varying conditions experienced in the field), on survivorship/lifespan, fecundity, and fertility of four pestiferous fruit fly species exhibiting contrasting life histories and belongi...
Source: Frontiers in Physiology - October 11, 2022 Category: Physiology Source Type: research
Molecules, Vol. 27, Pages 6157: Effect of D-Limonene Nanoemulsion Edible Film on Banana (Musa sapientum Linn.) Post-Harvest Preservation
Yu-Shen Liang
D-limonene (4-isopropenyl-1-methylcyclohexene) is an important compound in several citrus essential oils (such as orange, lemon, tangerine, lime, and grapefruit). It has been used as a flavoring agent and as a food preservative agent, with generally recognized as safe (GRAS) status. D-limonene has been well-studied for its anti-inflammatory, antioxidant, anti-cancer, and antibacterial properties. The antibacterial activity of D-limonene against food-borne pathogens was investigated in this study by preparing a D-limonene nanoemulsion. The D-limonene solution and nanoemulsion have been prepared in six co...
Source: Molecules - September 20, 2022 Category: Chemistry Authors: Chih-Yao Hou Sulfath Hakkim Hazeena Shu-Ling Hsieh Bao-Hong Li Min-Hung Chen Ping-Yu Wang Bao-Qing Zheng Yu-Shen Liang Tags: Article Source Type: research
Chitosan films with tunable droplet size of Pickering emulsions stabilized by amphiphilic konjac glucomannan network
Int J Biol Macromol. 2022 Aug 26:S0141-8130(22)01860-8. doi: 10.1016/j.ijbiomac.2022.08.157. Online ahead of print.ABSTRACTIn this work, chitosan (CS) emulsion films were prepared with grapefruit essential oil (GEO) Pickering emulsions (OGEOs) stabilized by amphiphilic octenyl succinic anhydride (OSA) konjac glucomannan (OSA-KGM) network. The droplet size of emulsion was regulated by altering oil content in OGEOs (10 %, 20 %, 30 % and 40 %, w/w). The structural and physicochemical properties of CS films with tunable emulsion droplets (OGEOs) were investigated. The droplet size of OGEOs increased with the increasing content...
Source: International Journal of Biological Macromolecules - August 29, 2022 Category: Biochemistry Authors: Nitong Bu Runzhi Sun Liying Huang Huanglong Lin Jie Pang Lin Wang Ruojun Mu Source Type: research
Chitosan films with tunable droplet size of Pickering emulsions stabilized by amphiphilic konjac glucomannan network
Int J Biol Macromol. 2022 Aug 27;220:1072-1083. doi: 10.1016/j.ijbiomac.2022.08.157. Online ahead of print.ABSTRACTIn this work, chitosan (CS) emulsion films were prepared with grapefruit essential oil (GEO) Pickering emulsions (OGEOs) stabilized by amphiphilic octenyl succinic anhydride (OSA) konjac glucomannan (OSA-KGM) network. The droplet size of emulsion was regulated by altering oil content in OGEOs (10 %, 20 %, 30 % and 40 %, w/w). The structural and physicochemical properties of CS films with tunable emulsion droplets (OGEOs) were investigated. The droplet size of OGEOs increased with the increasing content of GEO....
Source: International Journal of Biological Macromolecules - August 29, 2022 Category: Biochemistry Authors: Nitong Bu Runzhi Sun Liying Huang Huanglong Lin Jie Pang Lin Wang Ruojun Mu Source Type: research
Molecules, Vol. 27, Pages 4741: Analysis of Citrus Bioflavonoid Content and Dipeptidyl Peptidase-4 Inhibitory Potential of Commercially Available Supplements
n A. Jacobson
Citrus bioflavonoids are polyphenolic plant-derived pigments found in high levels in oranges, lemons, grapefruits and other citrus fruits. The three most abundant types of citrus bioflavonoids are hesperidin, naringenin and eriocitrin. Citrus bioflavonoids have long been known to possess powerful free radical-scavenging properties and cardioprotective effects. The study involved the analysis of 10 commercially available citrus bioflavonoid supplements from three different countries: Australia, the United States and Canada. The supplements were tested for their citrus bioflavonoid content which varied from...
Source: Molecules - July 25, 2022 Category: Chemistry Authors: Ankit Gupta Hayder A. Al-Aubaidy Christian K. Narkowicz Herbert F. Jelinek David S. Nichols John R. Burgess Glenn A. Jacobson Tags: Article Source Type: research
