310. Higher Infant Cortisol Levels Associated With Maternal Childhood Neglect and Larger Limbic Volumes
This study examined whether a) maternal childhood abuse or neglect is associated with infant cortisol output, b) infant cortisol is associated with infant limbic brain volumes, and c) infant cortisol mediates any relation between maternal childhood maltreatment and infant limbic brain volumes. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Miriam Chasson, Jennifer Khoury, Banu Ahtam, Leland Fleming, Yangming Ou, Michelle Bosquet Enlow, Ellen Grant, Karlen Lyons-Ruth Source Type: research
Correction: Presence of tuberculosis symptoms among HIV-positive men who have sex with men (MSM) in Zimbabwe
AIDS Res Ther. 2024 Apr 29;21(1):26. doi: 10.1186/s12981-024-00617-4.NO ABSTRACTPMID:38685106 | DOI:10.1186/s12981-024-00617-4 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 29, 2024 Category: Infectious Diseases Authors: Munyaradzi Mapingure Innocent Chingombe Tafadzwa Dzinamarira Brian Moyo Chesterfield Samba Delight Murigo Owen Mugurungi Elliot Mbunge Rutendo Birri Makota Grant Murewanhema Godfrey Musuka Source Type: research
Correction: Presence of tuberculosis symptoms among HIV-positive men who have sex with men (MSM) in Zimbabwe
(Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 29, 2024 Category: Infectious Diseases Authors: Munyaradzi Mapingure, Innocent Chingombe, Tafadzwa Dzinamarira, Brian Moyo, Chesterfield Samba, Delight Murigo, Owen Mugurungi, Elliot Mbunge, Rutendo Birri Makota, Grant Murewanhema and Godfrey Musuka Tags: Correction Source Type: research
The Ethics of Full Body Skin Exams (FBSE)
Full body skin examinations (FBSEs) are part of the purview of a dermatologic exam. Because this involves examination of sensitive or “intimate” areas, there are many ethical issues involved. Herein we discuss whether screening patients with a FBSE is ethical and consistent with the ethical tenet of distributive justice, how to ethically deal with our disabled patients, how to ethically navigate patients who have been emotiona lly or physically traumatized in the past, and the ethical ramifications of the use of a chaperone. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - April 29, 2024 Category: Dermatology Authors: Jane M. Grant-Kels Tags: Ethics of Total Body Examination Source Type: research
What Happens After a Neural Implant Study? Neuroethics Expert Workshop on Post-Trial Obligations
AbstractWhat happens at the end of a clinical trial for an investigational neural implant? It may be surprising to learn how difficult it is to answer this question. While new trials are initiated with increasing regularity, relatively little consensus exists on how best to conduct them, and even less on how to ethically end them. The landscape of recent neural implant trials demonstrates wide variability of what happens to research participants after an neural implant trial ends. Some former research participants continue to receive support for their devices (e.g., battery and component replacements, software updates, etc...
Source: Neuroethics - April 29, 2024 Category: Medical Ethics Source Type: research
In Vitro and In Silico Characterization of the Aggregation of Thrombi on Textured Ventricular Cannula
Ann Biomed Eng. 2024 Apr 28. doi: 10.1007/s10439-024-03504-1. Online ahead of print.ABSTRACTThe unacceptably high stroke rate associated with HeartMate 3 ventricular assist device (VAD) without signs of adherent pump thrombosis is hypothesized to be the result of the emboli produced by the inflow cannula, that are ingested and ejected from the pump. This in vitro and numerical study aimed to emulate the surface features and supraphysiological shear of a ventricular cannula to provide insight into their effect on thrombogenesis. Human whole blood was perfused at calibrated flow rates in a microfluidic channel to achieve she...
Source: Annals of Biomedical Engineering - April 28, 2024 Category: Biomedical Engineering Authors: Wenxuan He Abhishek Karmakar Junhyuk Kang Grant Rowlands Samuel Schirmacher Rodrigo M éndez-Rojano James Antaki Source Type: research
In Vitro and In Silico Characterization of the Aggregation of Thrombi on Textured Ventricular Cannula
Ann Biomed Eng. 2024 Apr 28. doi: 10.1007/s10439-024-03504-1. Online ahead of print.ABSTRACTThe unacceptably high stroke rate associated with HeartMate 3 ventricular assist device (VAD) without signs of adherent pump thrombosis is hypothesized to be the result of the emboli produced by the inflow cannula, that are ingested and ejected from the pump. This in vitro and numerical study aimed to emulate the surface features and supraphysiological shear of a ventricular cannula to provide insight into their effect on thrombogenesis. Human whole blood was perfused at calibrated flow rates in a microfluidic channel to achieve she...
Source: Annals of Biomedical Engineering - April 28, 2024 Category: Biomedical Engineering Authors: Wenxuan He Abhishek Karmakar Junhyuk Kang Grant Rowlands Samuel Schirmacher Rodrigo M éndez-Rojano James Antaki Source Type: research
High-resolution genomics identifies pneumococcal diversity and persistence of vaccine types in children with community-acquired pneumonia in the UK and Ireland
Streptococcus pneumoniae is a global cause of community-acquired pneumonia (CAP) and invasive disease in children. The CAP-IT trial (grant No. 13/88/11; (Source: BMC Microbiology)
Source: BMC Microbiology - April 27, 2024 Category: Microbiology Authors: Juan Pablo Rodriguez-Ruiz, Basil Britto Xavier, Wolfgang St öhr, Liesbet van Heirstraeten, Christine Lammens, Adam Finn, Herman Goossens, Julia Anna Bielicki, Michael Sharland and Surbhi Malhotra-Kumar Tags: Research Source Type: research
Ethics of Evaluating Dermatology Residency Applicants Based on Research Productivity
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - April 27, 2024 Category: Dermatology Authors: Idowu D. Olugbade, Albert E. Zhou, Neelesh P. Jain, Christian Gronbeck, Hao Feng, Jane M. Grant-Kels Tags: Dermatoethics Journal Club Source Type: research
Structures, aims and needs of early career scientists at the German Center for Mental Health
CONCLUSION: The DZPG will contribute to fostering ECS training programs for student and academic exchanges, collaborative research, and pooling of resources to acquire grants and scholarships. It will also support the establishment of hubs for ECS networks and promote the expansion of international competence of ECS in Germany.PMID:38668756 | DOI:10.1007/s00115-024-01631-7 (Source: Der Nervenarzt)
Source: Der Nervenarzt - April 26, 2024 Category: Neurology Authors: Shuyan Liu Simone C Behrens Bianca Besteher Edda Bilek Woo Ri Chae Vera Clemens Christoph Korn Verena Pflug Anni Richter Janine Selle Julie L O'Sullivan Ruth von Brachel Christina Totzeck Isabel Brandhorst Source Type: research
How smart was T. rex? Testing claims of exceptional cognition in dinosaurs and the application of neuron count estimates in palaeontological research
We present revised estimates of encephalization and telencephalic neuron counts in dinosaurs, which we derive from phylogenetically informed modeling and an amended dataset of endocranial measurements. For large-bodied theropods in particular, we recover significantly lower neuron counts than previously proposed. Furthermore, we review the suitability of neurological variables such as neuron numbers and relative brain size to predict cognitive complexity, metabolic rate and life history traits in dinosaurs, coming to the conclusion that they are flawed proxies for these biological phenomena. Instead of relying on such neur...
Source: Anatomical Record - April 26, 2024 Category: Anatomy Authors: Kai R Caspar Cristi án Gutiérrez-Ibáñez Ornella C Bertrand Thomas Carr Jennifer A D Colbourne Arthur Erb Hady George Thomas R Holtz Darren Naish Douglas R Wylie Grant R Hurlburt Source Type: research
Structures, aims and needs of early career scientists at the German Center for Mental Health
CONCLUSION: The DZPG will contribute to fostering ECS training programs for student and academic exchanges, collaborative research, and pooling of resources to acquire grants and scholarships. It will also support the establishment of hubs for ECS networks and promote the expansion of international competence of ECS in Germany.PMID:38668756 | DOI:10.1007/s00115-024-01631-7 (Source: Der Nervenarzt)
Source: Der Nervenarzt - April 26, 2024 Category: Neurology Authors: Shuyan Liu Simone C Behrens Bianca Besteher Edda Bilek Woo Ri Chae Vera Clemens Christoph Korn Verena Pflug Anni Richter Janine Selle Julie L O'Sullivan Ruth von Brachel Christina Totzeck Isabel Brandhorst Source Type: research
How smart was T. rex? Testing claims of exceptional cognition in dinosaurs and the application of neuron count estimates in palaeontological research
We present revised estimates of encephalization and telencephalic neuron counts in dinosaurs, which we derive from phylogenetically informed modeling and an amended dataset of endocranial measurements. For large-bodied theropods in particular, we recover significantly lower neuron counts than previously proposed. Furthermore, we review the suitability of neurological variables such as neuron numbers and relative brain size to predict cognitive complexity, metabolic rate and life history traits in dinosaurs, coming to the conclusion that they are flawed proxies for these biological phenomena. Instead of relying on such neur...
Source: Anatomical Record - April 26, 2024 Category: Anatomy Authors: Kai R Caspar Cristi án Gutiérrez-Ibáñez Ornella C Bertrand Thomas Carr Jennifer A D Colbourne Arthur Erb Hady George Thomas R Holtz Darren Naish Douglas R Wylie Grant R Hurlburt Source Type: research
Structures, aims and needs of early career scientists at the German Center for Mental Health
CONCLUSION: The DZPG will contribute to fostering ECS training programs for student and academic exchanges, collaborative research, and pooling of resources to acquire grants and scholarships. It will also support the establishment of hubs for ECS networks and promote the expansion of international competence of ECS in Germany.PMID:38668756 | DOI:10.1007/s00115-024-01631-7 (Source: Der Nervenarzt)
Source: Der Nervenarzt - April 26, 2024 Category: Neurology Authors: Shuyan Liu Simone C Behrens Bianca Besteher Edda Bilek Woo Ri Chae Vera Clemens Christoph Korn Verena Pflug Anni Richter Janine Selle Julie L O'Sullivan Ruth von Brachel Christina Totzeck Isabel Brandhorst Source Type: research
hadge: a comprehensive pipeline for donor deconvolution in single-cell studies
Single-cell multiplexing techniques (cell hashing and genetic multiplexing) combine multiple samples, optimizing sample processing and reducing costs. Cell hashing conjugates antibody-tags or chemical-oligonuc... (Source: Genome Biology)
Source: Genome Biology - April 26, 2024 Category: Genetics & Stem Cells Authors: Fabiola Curion, Xichen Wu, Lukas Heumos, Mylene Mariana Gonzales Andr é, Lennard Halle, Matiss Ozols, Melissa Grant-Peters, Charlotte Rich-Griffin, Hing-Yuen Yeung, Calliope A. Dendrou, Herbert B. Schiller and Fabian J. Theis Tags: Software Source Type: research
