Martin Burke: Replacing Lost Proteins to Treat Disease
As a medical student, Martin Burke, M.D., Ph.D., helped care for a young college student with cystic fibrosis (CF), an inherited disease that affects the body’s ability to make sweat and mucus. Dr. Burke had just studied CF in class, so he relayed what he had learned to her. He had a lot of information to give—doctors and researchers know the exact amino acid changes in an ion channel protein called cystic fibrosis transmembrane conductance regulator (CFTR) that cause CF.
Credit: UIUC News Bureau, Fred Zwicky.
“At one point in the conversation, she stopped me and said, ‘It sounds like you know exactly what’s...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 10, 2024 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Tools and Techniques Medicines Profiles Source Type: blogs
New U-RISE and MARC Funding Opportunities and Upcoming Webinar
We’re pleased to announce that the notices of funding opportunities (NOFOs) for the Undergraduate Research Training Initiative for Student Enhancement (U-RISE) (PAR-24-137) and Maximizing Access to Research Careers (MARC) (PAR-24-138) programs have been reissued. These NOFOs aim to promote broad participation in the biomedical research workforce by strengthening research training environments and expanding the pool of well-trained students who:
Complete their baccalaureate degree, and
Transition into and complete biomedical, research-focused higher degree programs (such as a Ph.D. or M.D./Ph.D.).
...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - April 9, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Meetings/Events Training/Fellowships/Career Development Preparing an Application Undergraduate Webinars Source Type: blogs
Integrated coaching in physician residency training [PODCAST]
Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! We sit down with psychiatrist Lind Grant-Oyeye to explore the transformative power of integrated coaching in physician residency training. We delve into the nuances of integrated coaching, its structured approach to continuous growth, and its significant impact on cultivating confident and
Read more…
Integrated coaching in physician residency training [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 8, 2024 Category: General Medicine Authors: The Podcast by KevinMD Tags: Podcast Psychiatry Source Type: blogs
Virtual Meeting for Advancing Research Careers (ARC) Predoc to Postdoc Transition Program (F99/K00) Applicants
We’re pleased to announce a virtual “office hour” on May 1 for potential applicants to our new Advancing Research Careers (ARC) predoctoral to postdoctoral transition award (F99/K00).
The ARC program is part of the National Institutes of Health’s efforts to promote broad participation within the biomedical research workforce. It has two components: an individual predoctoral to postdoctoral career transition award (F99/K00) and an institutional research education cooperative agreement (UE5) to provide these scholars with additional mentoring, networking, and professional development activities. The office hour w...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - April 4, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Meetings/Events Training/Fellowships/Career Development Biomedical Graduate Education Preparing an Application Webinars Source Type: blogs
The Long and Tortured History of Alpha-Synuclein and Parkinson ’s Disease
This study tracks the decades-long journey to harness alpha-synuclein as a treatment for Parkinson’s disease. Steven Zecola an activist who tracks Parkinson’s research and was on THCB last month discussing it, offers three key changes needed to overcome the underlying challenges.
A Quick Start for Alpha-Synuclein R&D
In the mid-1990’s, Parkinson’s patient advocacy groups had become impatient by the absence of any major therapeutic advances in the 25 years since L-dopa had been approved for Parkinson’s disease (PD).
The Director of National Institute of Neurological Disorders and Stroke (NINDS) se...
Source: The Health Care Blog - March 29, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice Parkinson's Disease Steven Zecola Source Type: blogs
SuRE R16 Program Funding Announcements and Upcoming Webinar
We’re pleased to announce that two funding opportunities for the Support for Research Excellence (SuRE) program have been reissued.
SuRE awards support investigator-initiated research projects in NIH mission areas and are open to faculty at institutions that award bachelor and/or graduate science degrees, receive limited NIH research support, and either serve a substantial number of students supported by Pell grants or are historically Black colleges and universities or Tribal colleges and universities. Faculty investigators who aren’t currently program directors/principal investigators (PD/PIs) of an active NIH res...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - March 28, 2024 Category: Biomedical Science Authors: Matt Mills Tags: Funding Opportunities Training/Fellowships/Career Development Preparing an Application Webinars Source Type: blogs
Investigating the Primary Cilium: Q & A With Xuecai Ge
Credit: Courtesy of Dr. Xuecai Ge.
The brain is a large and complex organ, but some very small structures guide its development. Xuecai Ge, Ph.D., an associate professor of molecular and cell biology at the University of California, Merced (UC Merced), has devoted her career to understanding one of these structures called the primary cilium. In an interview, Dr. Ge shared how her childhood experience inspired her to study science and what makes the primary cilium fascinating.
Q: How did you first become interested in science?
A: When I was a little kid, my mom was a primary care doctor, and I saw her treat patients...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - March 27, 2024 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Cellular Processes Profiles Source Type: blogs
Volunteer as a Peer Reviewer for NIGMS!
NIGMS supports a wide range of research, training, workforce development, and institutional capacity building grants in the biomedical sciences. While NIH’s Center for Scientific Review reviews the majority of our investigator-initiated research grants (read our post on NIGMS RPGs), NIGMS has its own scientific review branch (SRB) that manages the review of applications to programs in workforce development and in research capacity building (past posts on training and capacity building provide more information). These programs often require reviewers with unique experiences, in addition to scientific or technical expertis...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - March 25, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Peer Review Research Administration Peer Review Process Source Type: blogs
Sunday Sermonette: Weird Theology
Now we say goodbye to Asaph, and start what was evidently originally a new hymnal. " Gittith " is probably a musical instrument, but it could be a tune. The meaning is unknown. Anway, whenever these were composed, they aren ' t monotheistic. In psalm 84, Yahweh is the " God of gods " in verse 7, and otherwise the " Lord of hosts, " referring to an assemblage of god over which Yahweh is supreme. Psalm 85 is another of those that refers to some unspecified time in which the nation is afflicted and God seems to have withdrawn his favor. It does not seem to refer to the Babylonian exile, however, because the people seem s...
Source: Stayin' Alive - March 24, 2024 Category: American Health Source Type: blogs
Application and Funding Trends in Fiscal Year 2023
NIGMS continues to support a broad range of scientific topics and investigators within its research portfolio, including support for investigator-initiated research project grants (RPGs) at institutions throughout the country. As part of its commitment to transparency, NIGMS examines and publishes data on annual trends reflected in its RPG portfolio. In this post, we review and describe investigator-level trends associated with competing R01/R01-equivalent RPGs including those in the Institute’s R35 Maximizing Investigators’ Research Award (MIRA) program.
NIGMS Investigator-Level Trends Research Grants
In ord...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - March 20, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Director’s Messages Funding Trends Funding Outcomes Funding Policies MIRA NIGMS Strategic Plan R01 Source Type: blogs
Medical Scientist Training Program (MSTP) Funding Opportunity and Upcoming Webinar
We’re pleased to announce our Medical Scientist Training Program (MSTP) notice of funding opportunity (NOFO) has been reissued (PAR-24-128). This NOFO continues our support of eligible, domestic organizations to develop and implement effective, evidence-informed approaches to dual-degree training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise and lead to the completion of both a clinical degree (for example, M.D., D.O., D.V.M., D.D.S., Pharm.D.) and a research doctorate degree (Ph.D.). We expect that the proposed research training programs will incorporate didactic, resea...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - March 19, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Meetings/Events Training/Fellowships/Career Development Webinars Source Type: blogs
An assessment of the Institute for Research Design in Librarianship (IRDL)
When our second grant for the Institute for Research Design in Librarianship (IRDL) was ending in 2019, we wanted to take the opportunity to look back on the program, through the eyes of the 124 participants who had been through the program. The grant funding had been given to us to devise a model for continuing education for professional librarians and archivists with an interest in conducting research, so part of our looking back was to see if the model we designed had been impactful. We wanted to know about the possible short-term impacts, as well as longer-term impacts, the program had on their career trajectories, fro...
Source: Organization Monkey - March 18, 2024 Category: Databases & Libraries Authors: Marie Kennedy Tags: library Source Type: blogs
New NIGMS Resource: How-To Videos on Preparing NIH Training Tables
We’re pleased to announce the creation of informational videos on completing the NIH training tables. These videos take you through completing the NIH tables for undergraduate and graduate research training grant applications and, when applicable, research performance progress reports.
The following NIH training tables have informational videos* (accessible PDF versions are available on our website):
Undergraduate Training Programs
Table 2: Participating Faculty Members
Table 3: Federal Institutional Research Training Grants and Related Support Available to Participating Faculty Members
Table 4: Resea...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - March 14, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Research Administration Resources Training/Fellowships/Career Development Post-Award Monitoring and Reporting Preparing an Application Source Type: blogs
Sample NIGMS Data Management and Sharing Plans Now Available
Last year, NIH implemented a data management and sharing (DMS) policy to promote the sharing of scientific data. The policy requires that NIH grantees submit a DMS plan as part of their grant application. The great news is that most of our grantees already meet NIH’s DMS requirements, which we explain more fully in a list of FAQs.
To aid applicants and grantees in navigating this new policy, NIGMS has developed examples of acceptable plans for different types of applications including:
Research project grants (RPGs)
Small business innovation research (SBIR) and small business technology transfer (STTR)...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - March 13, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Research Administration Resources Source Type: blogs
The ‘Barbie Speech’ – How Much Has Really Changed For Women in America?
By MIKE MAGEE
In our world where up is down, and black is white, there is a left and a right – it’s the middle we appear to be missing. Does it exist, or was it make believe all along?
Into this existential despair enters Britt Cagle Grant, the 47-year old Federal Judge of the U.S. Court of Appeals for the Eleventh Circuit. The Stanford Law graduate, blessed by the Federalist Society and Leonard Leo, and former clerk of Hon. Brett Kavanaugh, was nominated by Donald Trump and confirmed by the Senate on July 31, 2018.
Now six years later, her words in rejecting DeSantis’s “Stop Woke Act” (otherwise kno...
Source: The Health Care Blog - March 11, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Barbie De Santis feminism Mike Magee Terry Sciaivo Source Type: blogs
