Differential DNA methylation associated with delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: a systematic review
AbstractRecent studies suggest that differential DNA methylation could play a role in the mechanism of cerebral vasospasm (CVS) and delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). Considering the significance of this matter and a lack of effective prophylaxis against DCI, we aim to summarize the current state of knowledge regarding their associations with DNA methylation and identify the gaps for a future trial. PubMed MEDLINE, Scopus, and Web of Science were searched by two authors in three waves for relevant DNA methylation association studies in DCI after aSAH. PRISMA checklist was follo...
Source: Neurosurgical Review - April 10, 2024 Category: Neurosurgery Source Type: research
Advice to a Young Mathematical Biologist
Bull Math Biol. 2024 Apr 9;86(5):52. doi: 10.1007/s11538-024-01269-1.ABSTRACTThis paper offers advice to early-mid career researchers in Mathematical Biology from ten past and current Presidents of the Society for Mathematical Biology. The topics covered include deciding if a career in academia is right for you; finding and working with a mentor; building collaborations and working with those from other disciplines; formulating a research question; writing a paper; reviewing papers; networking; writing fellowship or grant proposals; applying for faculty positions; and preparing and giving lectures. While written with mathe...
Source: Bulletin of Mathematical Biology - April 9, 2024 Category: Bioinformatics Authors: Paul A Roberts Source Type: research
Advice to a Young Mathematical Biologist
Bull Math Biol. 2024 Apr 9;86(5):52. doi: 10.1007/s11538-024-01269-1.ABSTRACTThis paper offers advice to early-mid career researchers in Mathematical Biology from ten past and current Presidents of the Society for Mathematical Biology. The topics covered include deciding if a career in academia is right for you; finding and working with a mentor; building collaborations and working with those from other disciplines; formulating a research question; writing a paper; reviewing papers; networking; writing fellowship or grant proposals; applying for faculty positions; and preparing and giving lectures. While written with mathe...
Source: Bulletin of Mathematical Biology - April 9, 2024 Category: Bioinformatics Authors: Paul A Roberts Source Type: research
Neurocognition and its predictors in a linguistically and culturally diverse cohort of people with HIV
Conclusions: Findings suggest worse neurocognition among English-speaking Latino PWH compared to Whites. Predictors of neurocognitive function among PWH differ across ethnic/racial and language groups. Consideration of these HIV disease characteristics and comorbidities may be valuable in developing targeted culturally-relevant interventions aimed at ameliorating neurocognitive dysfunction among diverse PWH.PMID:38588669 | DOI:10.1080/13854046.2024.2319900 (Source: The Clinical Neuropsychologist)
Source: The Clinical Neuropsychologist - April 8, 2024 Category: Psychiatry & Psychology Authors: Jordana Breton Caitlin Wei-Ming Watson Lily Kamalyan Donald Franklin Pariya Fazeli Anya Umlauf Raeanne C Moore Ronald Ellis Igor Grant Robert K Heaton Mariana Cherner David J Moore Mar ía J Marquine Source Type: research
Characterization of peer support services for substance use disorders in 11 US emergency departments in 2020: findings from a NIDA clinical trials network site selection process
CONCLUSIONS: The majority of ED-based PSSs were funded through time-limited grants, and short-term grant funding was identified as a barrier for ED PSS programs. There was consistency among sites in the involvement of PSSs in facilitation of transitions of SUD care, coordination of follow-up after ED discharge, and PSS involvement in naloxone distribution.PMID:38589934 | PMC:PMC11003047 | DOI:10.1186/s13722-024-00453-x (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - April 8, 2024 Category: Addiction Authors: Lindsey K Jennings Laura Lander Tricia Lawdahl Erin A McClure Angela Moreland Jenna L McCauley Louise Haynes Timothy Matheson Richard Jones Thomas E Robey Sarah Kawasaki Phillip Moschella Amer Raheemullah Suzette Miller Gina Gregovich Deborah Waltman Kath Source Type: research
Neurocognition and its predictors in a linguistically and culturally diverse cohort of people with HIV
Conclusions: Findings suggest worse neurocognition among English-speaking Latino PWH compared to Whites. Predictors of neurocognitive function among PWH differ across ethnic/racial and language groups. Consideration of these HIV disease characteristics and comorbidities may be valuable in developing targeted culturally-relevant interventions aimed at ameliorating neurocognitive dysfunction among diverse PWH.PMID:38588669 | DOI:10.1080/13854046.2024.2319900 (Source: The Clinical Neuropsychologist)
Source: The Clinical Neuropsychologist - April 8, 2024 Category: Psychiatry & Psychology Authors: Jordana Breton Caitlin Wei-Ming Watson Lily Kamalyan Donald Franklin Pariya Fazeli Anya Umlauf Raeanne C Moore Ronald Ellis Igor Grant Robert K Heaton Mariana Cherner David J Moore Mar ía J Marquine Source Type: research
Characterization of peer support services for substance use disorders in 11 US emergency departments in 2020: findings from a NIDA clinical trials network site selection process
CONCLUSIONS: The majority of ED-based PSSs were funded through time-limited grants, and short-term grant funding was identified as a barrier for ED PSS programs. There was consistency among sites in the involvement of PSSs in facilitation of transitions of SUD care, coordination of follow-up after ED discharge, and PSS involvement in naloxone distribution.PMID:38589934 | DOI:10.1186/s13722-024-00453-x (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - April 8, 2024 Category: Addiction Authors: Lindsey K Jennings Laura Lander Tricia Lawdahl Erin A McClure Angela Moreland Jenna L McCauley Louise Haynes Timothy Matheson Richard Jones Thomas E Robey Sarah Kawasaki Phillip Moschella Amer Raheemullah Suzette Miller Gina Gregovich Deborah Waltman Kath Source Type: research
Mitotic abnormalities precede microsatellite instability in lynch syndrome-associated colorectal tumourigenesis
This study aimed to identify precancerous functional changes in colonic mucosa that could facilitate the monitoring and prevention of cancer development in LS.METHODS: The study material comprised colon biopsy specimens (n = 71) collected during colonoscopy examinations from LS carriers (tumour-free, or diagnosed with adenoma, or diagnosed with carcinoma) and a control group, which included sporadic cases without LS or neoplasia. The majority (80%) of LS carriers had an inherited genetic MLH1 mutation. The remaining 20% included MSH2 mutation carriers (13%) and MSH6 mutation carriers (7%). The transcriptomes were first ana...
Source: Cancer Control - April 7, 2024 Category: Cancer & Oncology Authors: Marjaana Pussila Aleksi Laiho Petri T örönen Pauliina Bj örkbacka Sonja Nyk änen Kirsi Pylv änäinen Liisa Holm Jukka-Pekka Mecklin Laura Renkonen-Sinisalo Taru Lehtonen Anna Lepist ö Jere Linden Satu M äki-Nevala P äivi Peltomäki Minna Nystr öm Source Type: research
Zanubrutinib - Relapsed or refractory follicular lymphoma
Bull Cancer. 2024 Apr 5:S0007-4551(24)00115-2. doi: 10.1016/j.bulcan.2024.02.009. Online ahead of print.NO ABSTRACTPMID:38582740 | DOI:10.1016/j.bulcan.2024.02.009 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Fiona Grant-Monlouis-Felicite Nadia Diop Source Type: research
Zanubrutinib - Relapsed or refractory follicular lymphoma
Bull Cancer. 2024 Apr 5:S0007-4551(24)00115-2. doi: 10.1016/j.bulcan.2024.02.009. Online ahead of print.NO ABSTRACTPMID:38582740 | DOI:10.1016/j.bulcan.2024.02.009 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Fiona Grant-Monlouis-Felicite Nadia Diop Source Type: research
Zanubrutinib - Relapsed or refractory follicular lymphoma
Bull Cancer. 2024 Apr 5:S0007-4551(24)00115-2. doi: 10.1016/j.bulcan.2024.02.009. Online ahead of print.NO ABSTRACTPMID:38582740 | DOI:10.1016/j.bulcan.2024.02.009 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Fiona Grant-Monlouis-Felicite Nadia Diop Source Type: research
Zanubrutinib - Relapsed or refractory follicular lymphoma
Bull Cancer. 2024 Apr 5:S0007-4551(24)00115-2. doi: 10.1016/j.bulcan.2024.02.009. Online ahead of print.NO ABSTRACTPMID:38582740 | DOI:10.1016/j.bulcan.2024.02.009 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Fiona Grant-Monlouis-Felicite Nadia Diop Source Type: research
Zanubrutinib - Relapsed or refractory follicular lymphoma
Bull Cancer. 2024 Apr 5:S0007-4551(24)00115-2. doi: 10.1016/j.bulcan.2024.02.009. Online ahead of print.NO ABSTRACTPMID:38582740 | DOI:10.1016/j.bulcan.2024.02.009 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - April 6, 2024 Category: Cancer & Oncology Authors: Fiona Grant-Monlouis-Felicite Nadia Diop Source Type: research
A new section in JAAD: Humanities
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - April 6, 2024 Category: Dermatology Authors: Dirk M. Elston, Jane M. Grant-Kels, Arianne Shadi Kourosh Source Type: research
Is Transcatheter Aortic Valve Implantation (TAVI) Activity in Australia Consistent With International Guidelines?
This study was undertaken to provide an update on the status of TAVI activity in Australia. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - April 6, 2024 Category: Cardiology Authors: Jonathon B. Ryan, Peter W. Grant Tags: Original Article Source Type: research
