Use of harm reduction strategies among individuals with a history of incarceration: A short report using baseline data collected from the STAMINA clinical trial
Due to the considerably heightened risk of overdose immediately following jail or prison release, expansion of harm reduction interventions for citizens returning to the community after an incarceration episode should be of utmost concern. However, there are no studies examining the adoption and use of harm reduction among this population. This short report examines the use of individual-level harm reduction strategies (HRS) among people who use drugs, comparing those who have lifetime histories of incarceration with those who do not. (Source: Journal of Substance Abuse Treatment)
Source: Journal of Substance Abuse Treatment - April 16, 2024 Category: Addiction Authors: Grant Victor, Bradley Ray, Dennis P. Watson Source Type: research
The HIV-1 reservoir landscape in persistent elite controllers and transient elite controllers
CONCLUSIONS These results suggest the need for, and can give guidance to, the design of future research to identify a distinct proviral landscape that may be associated with the persistent control of HIV-1 without ART.FUNDING Instituto de Salud Carlos III (FI17/00186, FI19/00083, MV20/00057, PI18/01532, PI19/01127 and PI22/01796), Gilead Fellowships (GLD22/00147). NIH grants AI155171, AI116228, AI078799, HL134539, DA047034, MH134823, amfAR ARCHE and the Bill and Melinda Gates Foundation. (Source: Journal of Clinical Investigation)
Source: Journal of Clinical Investigation - April 15, 2024 Category: Biomedical Science Authors: Carmen Gasca-Capote, Xiaodong Lian, Ce Gao, Isabelle C. Roseto, María Reyes Jiménez-León, Gregory Gladkov, María Inés Camacho-Sojo, Alberto Pérez-Gómez, Isabel Gallego, Luis E. Lopez-Cortes, Sara Bachiller, Joana Vitalle, Mohamed Rafii-El-Idrissi B Source Type: research
Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals
CONCLUSION These findings suggest that nAIGAs are isolated and that their penetrance in HLA-DRB1*15:02 or 16:02 individuals is low, implying that they may be triggered by rare germline or somatic variants. In contrast, the risk of mycobacterial disease in patients with nAIGAs is high, confirming that these nAIGAs are the cause of EM disease.FUNDING The Laboratory of Human Genetics of Infectious Diseases is supported by the Howard Hughes Medical Institute, the Rockefeller University, the St. Giles Foundation, the National Institutes of Health (NIH) (R01AI095983 and U19AIN1625568), the National Center for Advancing Translati...
Source: Journal of Clinical Investigation - April 15, 2024 Category: Biomedical Science Authors: Jessica N. Peel, Rui Yang, Tom Le Voyer, Adrian Gervais, Jérémie Rosain, Paul Bastard, Anish Behere, Axel Cederholm, Aaron Bodansky, Yoann Seeleuthner, Clément Conil, Jing-Ya Ding, Wei-Te Lei, Lucy Bizien, Camille Soudee, Mélanie Migaud, Masato Ogishi Source Type: research
Comparisons between dxa and bioimpedance devices for appendicular lean mass and muscle quality in hispanic adults
Br J Nutr. 2024 Apr 15:1-24. doi: 10.1017/S000711452400076X. Online ahead of print.ABSTRACTThe purpose of this study was to compare single- and multi-frequency bioimpedance (BIA) devices against dual energy X-ray absorptiometry (DXA) for appendicular lean mass (ALM) and muscle quality index (MQI) metrics in Hispanic adults. One-hundred thirty-one Hispanic adults (18-55 yrs.) participated in this study. ALM was measured with single-frequency (SFBIA), multi-frequency (MFBIA), and DXA. ALMTOTAL (left arm + right arm + left leg + right leg) and ALMARMS (left arm + right arm) were computed for all three devices. Handgrip streng...
Source: The British Journal of Nutrition - April 15, 2024 Category: Nutrition Authors: Bassel Nassar Grant M Tinsley Kyung-Shin Park Stefan A Czerwinski Brett S Nickerson Source Type: research
Divalent Titanium via Reductive N-C Coupling of a TiIV Nitrido with π-Acids
Angew Chem Int Ed Engl. 2024 Apr 15:e202404601. doi: 10.1002/anie.202404601. Online ahead of print.ABSTRACTThe nitrido-ate complex [(PN)2Ti(N){μ2-K(OEt2)}]2 (1) reductively couples CO and isocyanides in the presence of DME or cryptand, to form rare, five-coordinate TiII complexes having a linear cumulene motif, [K(L)][(PN)2Ti(NCE)] (E = O, L = Kryptofix222, (2); E = NAd, L = 3 DME, (3); E = NtBu, L = 3 DME, (4); E = NAd, L = Kryptofix222, (5)). Oxidation of 2-5 with [Fc][OTf] afforded an isostructural TiIII center containing a neutral cumulene [(PN)2Ti(NCE)] (E = O, (6); E = NAd (7), NtBu (8)). Moreover, 1e- reduction of ...
Source: Angewandte Chemie - April 15, 2024 Category: Chemistry Authors: Mrinal Bhunia Christian Sandoval-Pauker Dominik Fehn Lauren Grant Shuruthi Senthil Michael Gau Andrew Ozarowski Jurek Krzystek Joshua Telser Balazs Pinter Karsten Meyer Daniel J Mindiola Source Type: research
Comparisons between dxa and bioimpedance devices for appendicular lean mass and muscle quality in hispanic adults
Br J Nutr. 2024 Apr 15:1-24. doi: 10.1017/S000711452400076X. Online ahead of print.ABSTRACTThe purpose of this study was to compare single- and multi-frequency bioimpedance (BIA) devices against dual energy X-ray absorptiometry (DXA) for appendicular lean mass (ALM) and muscle quality index (MQI) metrics in Hispanic adults. One-hundred thirty-one Hispanic adults (18-55 yrs.) participated in this study. ALM was measured with single-frequency (SFBIA), multi-frequency (MFBIA), and DXA. ALMTOTAL (left arm + right arm + left leg + right leg) and ALMARMS (left arm + right arm) were computed for all three devices. Handgrip streng...
Source: The British Journal of Nutrition - April 15, 2024 Category: Nutrition Authors: Bassel Nassar Grant M Tinsley Kyung-Shin Park Stefan A Czerwinski Brett S Nickerson Source Type: research
Divalent Titanium via Reductive N-C Coupling of a TiIV Nitrido with π-Acids
Angew Chem Int Ed Engl. 2024 Apr 15:e202404601. doi: 10.1002/anie.202404601. Online ahead of print.ABSTRACTThe nitrido-ate complex [(PN)2Ti(N){μ2-K(OEt2)}]2 (1) reductively couples CO and isocyanides in the presence of DME or cryptand, to form rare, five-coordinate TiII complexes having a linear cumulene motif, [K(L)][(PN)2Ti(NCE)] (E = O, L = Kryptofix222, (2); E = NAd, L = 3 DME, (3); E = NtBu, L = 3 DME, (4); E = NAd, L = Kryptofix222, (5)). Oxidation of 2-5 with [Fc][OTf] afforded an isostructural TiIII center containing a neutral cumulene [(PN)2Ti(NCE)] (E = O, (6); E = NAd (7), NtBu (8)). Moreover, 1e- reduction of ...
Source: Angewandte Chemie - April 15, 2024 Category: Chemistry Authors: Mrinal Bhunia Christian Sandoval-Pauker Dominik Fehn Lauren Grant Shuruthi Senthil Michael Gau Andrew Ozarowski Jurek Krzystek Joshua Telser Balazs Pinter Karsten Meyer Daniel J Mindiola Source Type: research
Comparisons between dxa and bioimpedance devices for appendicular lean mass and muscle quality in hispanic adults
Br J Nutr. 2024 Apr 15:1-24. doi: 10.1017/S000711452400076X. Online ahead of print.ABSTRACTThe purpose of this study was to compare single- and multi-frequency bioimpedance (BIA) devices against dual energy X-ray absorptiometry (DXA) for appendicular lean mass (ALM) and muscle quality index (MQI) metrics in Hispanic adults. One-hundred thirty-one Hispanic adults (18-55 yrs.) participated in this study. ALM was measured with single-frequency (SFBIA), multi-frequency (MFBIA), and DXA. ALMTOTAL (left arm + right arm + left leg + right leg) and ALMARMS (left arm + right arm) were computed for all three devices. Handgrip streng...
Source: The British Journal of Nutrition - April 15, 2024 Category: Nutrition Authors: Bassel Nassar Grant M Tinsley Kyung-Shin Park Stefan A Czerwinski Brett S Nickerson Source Type: research
Exploring the learning preferences of farmworker ‐serving community health workers
This study provides librarians, along with public health and medical professionals, with useful information about learning preferences to inform the creation of new and varied learning materials for community health workers. (Source: Health Information and Libraries Journal)
Source: Health Information and Libraries Journal - April 15, 2024 Category: Databases & Libraries Authors: Hannah Gordon,
Genesis Ramirez,
Emery L. Harwell,
Jamie E. Bloss,
Ra úl Gámez,
Catherine E. LePrevost Tags: REGULAR FEATURE ARTICLE Source Type: research
‘Shrugging off failure is hard’: the $400-million grant setback that shaped the Smithsonian lead scientist’s career
Nature, Published online: 15 April 2024; doi:10.1038/d41586-024-01108-2Planetary scientist Ellen Stofan thought about leaving research after a funding bid was rejected. But new opportunities emerged. (Source: Nature AOP)
Source: Nature AOP - April 15, 2024 Category: Research Authors: Anne Gulland Source Type: research
The Cluster Model of Energy Transduction in Biological Systems
Biosystems. 2024 Apr 12:105213. doi: 10.1016/j.biosystems.2024.105213. Online ahead of print.ABSTRACTThe central problem in transduction is to explain how the energy caught from sunlight by chloroplasts becomes biological work. Or to express it in different terms: how does the energy remain trapped in the biological network and not get lost through thermalization into the environment? The pathway consists of an immensely large number of steps crossing hierarchical levels - some upwards, to larger assemblies, others downwards into energy rich molecules - before fuelling an action potential or a contracting cell. Accepting t...
Source: Biosystems - April 14, 2024 Category: Biotechnology Authors: John Grant Watterson Source Type: research
The Cluster Model of Energy Transduction in Biological Systems
Biosystems. 2024 Apr 12:105213. doi: 10.1016/j.biosystems.2024.105213. Online ahead of print.ABSTRACTThe central problem in transduction is to explain how the energy caught from sunlight by chloroplasts becomes biological work. Or to express it in different terms: how does the energy remain trapped in the biological network and not get lost through thermalization into the environment? The pathway consists of an immensely large number of steps crossing hierarchical levels - some upwards, to larger assemblies, others downwards into energy rich molecules - before fuelling an action potential or a contracting cell. Accepting t...
Source: Biosystems - April 14, 2024 Category: Biotechnology Authors: John Grant Watterson Source Type: research
Traveling the road toward academic promotion for faculty with a DNP degree
This article provides strategies to support nursing faculty planning to embark on an academic career track and provides guidance on how to prepare these DNP-prepared faculty for career progression and future promotion along academic ranks. These strategies include school and institutional orientation, faculty development plans, mentorship, leadership development, and performance review processes.PMID:38614677 | DOI:10.1016/j.profnurs.2024.01.012 (Source: Journal of Professional Nursing)
Source: Journal of Professional Nursing - April 13, 2024 Category: Nursing Authors: Kaitrin Parris Allison Shorten Sigrid Ladores Felesia R Bowen S Danielle Baker Joan S Grant Source Type: research
Traveling the road toward academic promotion for faculty with a DNP degree
This article provides strategies to support nursing faculty planning to embark on an academic career track and provides guidance on how to prepare these DNP-prepared faculty for career progression and future promotion along academic ranks. These strategies include school and institutional orientation, faculty development plans, mentorship, leadership development, and performance review processes.PMID:38614677 | DOI:10.1016/j.profnurs.2024.01.012 (Source: Journal of Professional Nursing)
Source: Journal of Professional Nursing - April 13, 2024 Category: Nursing Authors: Kaitrin Parris Allison Shorten Sigrid Ladores Felesia R Bowen S Danielle Baker Joan S Grant Source Type: research
Traveling the road toward academic promotion for faculty with a DNP degree
This article provides strategies to support nursing faculty planning to embark on an academic career track and provides guidance on how to prepare these DNP-prepared faculty for career progression and future promotion along academic ranks. These strategies include school and institutional orientation, faculty development plans, mentorship, leadership development, and performance review processes.PMID:38614677 | DOI:10.1016/j.profnurs.2024.01.012 (Source: Journal of Professional Nursing)
Source: Journal of Professional Nursing - April 13, 2024 Category: Nursing Authors: Kaitrin Parris Allison Shorten Sigrid Ladores Felesia R Bowen S Danielle Baker Joan S Grant Source Type: research
