Stigma associated with medication treatment for young adults with opioid use disorder: a case series.
CONCLUSIONS: Opioid-related deaths continue to rise among all age groups, including young adults. Stigma related to medication treatment can be a substantial barrier for many young adult patients but there are concrete steps that providers and communities can take to address this stigma. PMID: 29730987 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - May 7, 2018 Category: Addiction Authors: Hadland SE, Park TW, Bagley SM Tags: Addict Sci Clin Pract Source Type: research

Under one roof: identification, evaluation, and treatment of chronic hepatitis C in addiction care.
We describe here both the need for and process of chronic HCV care under the roof of addiction medicine. PMID: 29690936 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - April 25, 2018 Category: Addiction Authors: Martin SA, Bosse J, Wilson A, Losikoff P, Chiodo L Tags: Addict Sci Clin Pract Source Type: research

Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research.
This article reviews current research evaluating MBIs as a treatment for addiction, with a focus on findings pertaining to clinical outcomes and biobehavioral mechanisms. Studies indicate that MBIs reduce substance misuse and craving by modulating cognitive, affective, and psychophysiological processes integral to self-regulation and reward processing. This integrative review provides the basis for manifold recommendations regarding the next wave of research needed to firmly establish the efficacy of MBIs and elucidate the mechanistic pathways by which these therapies ameliorate addiction. Issues pertaining to MBI treatmen...
Source: Addiction Science and Clinical Practice - April 18, 2018 Category: Addiction Authors: Garland EL, Howard MO Tags: Addict Sci Clin Pract Source Type: research

Barriers and facilitators affecting the implementation of substance use screening in primary care clinics: a qualitative study of patients, providers, and staff.
CONCLUSIONS: Participants expressed support for substance use screening as a valuable part of medical care, and identified individual-level as well as systems-level barriers to its implementation. These findings suggest that screening programs should clearly communicate the goals of screening to patients and proactively counteract stigma, address staff concerns regarding time and workflow, and provide education as well as treatment resources to primary care providers. PMID: 29628018 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - April 9, 2018 Category: Addiction Authors: McNeely J, Kumar PC, Rieckmann T, Sedlander E, Farkas S, Chollak C, Kannry JL, Vega A, Waite EA, Peccoralo LA, Rosenthal RN, McCarty D, Rotrosen J Tags: Addict Sci Clin Pract Source Type: research

Adherence intervention for HIV-infected persons who use drugs: adaptation, open trial, and pilot randomized hybrid type 1 trial protocol.
This study protocol seeks to improve clinical practice by adapting Life Steps for HIV-infected PWUD and adding a brief motivational intervention addressing drug use. This intervention will incorporate educational, motivational, and behavioral skills components specifically aimed at improving adherence and linkage to substance use treatment among HIV-infected PWUD. METHODS: This project will consist of three phases using a mixed-methods approach. In Phase 1, qualitative interviews with HIV-infected PWUD and community providers, coupled with feedback from an expert review panel, will be used to enhance the existing Life...
Source: Addiction Science and Clinical Practice - April 2, 2018 Category: Addiction Authors: Claborn K, Becker S, Operario D, Safren S, Rich JD, Ramsey S Tags: Addict Sci Clin Pract Source Type: research

Evaluation of the effect of methamphetamine on traumatic injury complications and outcomes.
This study investigates the impact of methamphetamine use on trauma patient outcomes. METHODS: This retrospective study analyzed patients between 18 and 55 years old presenting to a single trauma center in San Bernardino County, CA who sustained traumatic injury during the 10-year study period (January 1st, 2005 to December 31st, 2015). Routine serum ethanol levels and urine drug screens (UDS) were completed on all trauma patients. Exclusion criteria included patients with an elevated serum ethanol level (> 0 mg/dL). Those who screened positive on UDS for only methamphetamine and negative for cocai...
Source: Addiction Science and Clinical Practice - March 29, 2018 Category: Addiction Authors: Neeki MM, Dong F, Liang L, Toy J, Carrico B, Jabourian N, Sin A, Hussain F, Brown S, Safdari K, Borger R, Wong D Tags: Addict Sci Clin Pract Source Type: research

Standardised alcohol screening in primary health care services targeting Aboriginal and Torres Strait Islander peoples in Australia.
CONCLUSIONS: Detection of unhealthy drinking before harms occur is a goal of screening, so AUDIT-C offers advantages over tools like IRIS or CAGE which focus on dependence. AUDIT-C's brevity suits integration with general health screening. Further research is needed on facilitating implementation of systematic alcohol screening into Indigenous primary healthcare. PMID: 29592801 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 29, 2018 Category: Addiction Authors: Islam MM, Oni HT, Lee KSK, Hayman N, Wilson S, Harrison K, Hummerston B, Ivers R, Conigrave KM Tags: Addict Sci Clin Pract Source Type: research

How do people with mood and anxiety disorders perceive and interpret the Drinking Motives Questionnaire? A think-aloud study in a clinical setting.
CONCLUSIONS: Taken together, the results suggest a support for the use of DMQ-R also in the group of psychiatric outpatients. Still, when interpreting the DMQ-R, a certain insecurity of the exactness of answers should be considered. The graphic design should be particularly clear in this group of patients. PMID: 29534735 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 14, 2018 Category: Addiction Authors: Nehlin C, Wennberg M, Öster C Tags: Addict Sci Clin Pract Source Type: research

Substance use and the HIV care continuum: important advances.
PMID: 29530080 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 12, 2018 Category: Addiction Authors: Korthuis PT, Edelman EJ Tags: Addict Sci Clin Pract Source Type: research

Development and differentiability of three brief interventions for risky alcohol use that include varying doses of motivational interviewing.
CONCLUSIONS: The three interventions can be used in future trials to prospectively examine the role MI has in determining BI outcome. Trial registration clinicaltrials.gov NCT02978027, retrospectively registered 11/28/16. PMID: 29482632 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - February 27, 2018 Category: Addiction Authors: Hettema JE, Cockrell SA, Reeves A, Ingersoll KS, Lum PJ, Saitz R, Murray-Krezan CM, Carrejo VA Tags: Addict Sci Clin Pract Source Type: research

Correction to: Testing the effectiveness of a motivational interviewing-based brief intervention for substance use as an adjunct to usual care in community-based AIDS service organizations: study protocol for a multisite randomized controlled trial.
Abstract Upon publication of the original article. PMID: 29467033 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - February 21, 2018 Category: Addiction Authors: Garner BR, Gotham HJ, Tueller SJ, Ball EL, Kaiser D, Stilen P, Speck K, Vandersloot D, Rieckmann TR, Chaple M, Martin EG, Martino S Tags: Addict Sci Clin Pract Source Type: research

Eligibility for heroin-assisted treatment (HAT) among people who inject opioids and are living with HIV in a Canadian setting.
CONCLUSIONS: In our study of HIV-positive people with a history of injection drug use, approximately 20% of participants were eligible for HAT at ≥ 1 follow-up period. Eligibility was linked to risk factors for sub-optimal HIV/AIDS treatment outcomes, such as homelessness and involvement in the local illicit drug trade, suggesting that scaling-up access to HAT might contribute to achieving optimal HIV treatment in this setting. PMID: 29409539 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - February 7, 2018 Category: Addiction Authors: Klimas J, Dong H, Fairbairn N, Socías E, Barrios R, Wood E, Kerr T, Montaner J, Milloy MJ Tags: Addict Sci Clin Pract Source Type: research

Racial/ethnic differences in the association between alcohol use and mortality among men living with HIV.
CONCLUSION: Among all PLWH, mortality risk was increased among patients reporting high-risk alcohol use across all racial/ethnic groups, but mortality risk was only increased among patients reporting moderate-risk relative to lower-risk alcohol use among white PLWH, and black patients appeared to have higher mortality risk relative to white patients at lower-risk levels of alcohol use. Findings of the present study further underscore the need to address unhealthy alcohol use among PLWH, and future research is needed to understand mechanisms underlying observed differences. PMID: 29353555 [PubMed - in process] (Source:...
Source: Addiction Science and Clinical Practice - January 22, 2018 Category: Addiction Authors: Bensley KM, McGinnis KA, Fiellin DA, Gordon AJ, Kraemer KL, Bryant KJ, Edelman EJ, Crystal S, Gaither JR, Korthuis PT, Marshall BDL, Ornelas IJ, Chan KCG, Dombrowski JC, Fortney JC, Justice AC, Williams EC Tags: Addict Sci Clin Pract Source Type: research

Effect of exercise versus cognitive behavioural therapy or no intervention on anxiety, depression, fitness and quality of life in adults with previous methamphetamine dependency: a systematic review.
Abstract BACKGROUND: Methamphetamine (MA) is a highly addictive psychostimulant used by approximately 52 million people worldwide. Chronic MA abuse leads to detrimental physiological and neurological changes, as well as increases in anxiety and depression, and decreases in overall fitness and quality of life. Exercise has been reported to possibly reverse physiological and neurological damage caused by previous MA use, and to reduce anxiety and depression in this population. The aim of this systematic review was to identify, clinically appraise and synthesise the available evidence for the effe...
Source: Addiction Science and Clinical Practice - January 16, 2018 Category: Addiction Authors: Morris L, Stander J, Ebrahim W, Eksteen S, Meaden OA, Ras A, Wessels A Tags: Addict Sci Clin Pract Source Type: research

Developing adaptive interventions for adolescent substance use treatment settings: protocol of an observational, mixed-methods project.
DISCUSSION: This project begins filling a major gap in clinical and research efforts for adolescents in substance use treatment. Findings could be used to inform the further development and revision of influential multi-dimensional assessment and treatment planning tools, or lay the foundation for subsequent experiments to further develop or test AIs for treatment planning. PMID: 29254500 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - December 19, 2017 Category: Addiction Authors: Grant S, Agniel D, Almirall D, Burkhart Q, Hunter SB, McCaffrey DF, Pedersen ER, Ramchand R, Griffin BA Tags: Addict Sci Clin Pract Source Type: research

Changes in Specific Substance Involvement Scores among SBIRT recipients in an HIV primary care setting.
CONCLUSIONS: Substance use among patients in this urban, safety-net, HIV primary care clinic was near universal, and moderate risk substance use was common. Among participants who received the SBIRT intervention, mean SSISs decreased among those at moderate-high risk at baseline, but increased among those at lower risk at baseline over the 6-month study period. Additional research should examine the clinical significance of SSIS changes for PLHIV, which SBIRT components drive changes in substance use scores, and what other interventions might support those patients at lower risk to maintain health and engagement along the ...
Source: Addiction Science and Clinical Practice - December 12, 2017 Category: Addiction Authors: Dawson-Rose C, Draughon JE, Cuca Y, Zepf R, Huang E, Cooper BA, Lum PJ Tags: Addict Sci Clin Pract Source Type: research

Delivery of screening and brief intervention for unhealthy alcohol use in an urban academic Federally Qualified Health Center.
CONCLUSIONS: Our model of SBI resulted in screening of nearly half of all eligible patients and BI provision to over half of those screening positive. Future efforts to improve SBI delivery should focus on groups such as older adults, women, and those with chronic medical conditions. PMID: 29212532 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - December 7, 2017 Category: Addiction Authors: Bachhuber MA, O'Grady MA, Chung H, Neighbors CJ, DeLuca J, D'Aloia EM, Diaz A, Cunningham CO Tags: Addict Sci Clin Pract Source Type: research

Patterns of HIV testing, drug use, and sexual behaviors in people who use drugs: findings from a community-based outreach program in Phnom Penh, Cambodia.
CONCLUSIONS: A peer-led community-based approach was effective in reaching people who use drugs with HIV and harm reduction interventions. To mitigate ongoing HIV risks, expanding access to combination prevention interventions and implementing strategies to enable people who use drugs to objectively assess their HIV risks are required. Additionally, community-based programs should collect data along the care continuum, to enable decentralized tracking of progress towards 90-90-90 goals at local levels. PMID: 29202872 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - December 5, 2017 Category: Addiction Authors: Mburu G, Ngin C, Tuot S, Chhoun P, Pal K, Yi S Tags: Addict Sci Clin Pract Source Type: research

Role of substance use in HIV care cascade outcomes among people who inject drugs in Russia.
Abstract BACKGROUND: Engaging people who drink alcohol or inject drugs in HIV care can be challenging, particularly in Eastern Europe. Healthcare facilities in Russia are organized by specialty; therefore linking patients from addiction care to HIV hospitals has been difficult. The HIV care cascade outlines stages of HIV care (e.g., linkage to care, prescribed antiretroviral therapy [ART], and achieving HIV viral suppression). We hypothesized that unhealthy alcohol use, injection drug use, and opioid craving are associated with unfavorable HIV care cascade outcomes. METHODS: We analyzed data from a cohort (n&...
Source: Addiction Science and Clinical Practice - December 4, 2017 Category: Addiction Authors: Idrisov B, Lunze K, Cheng DM, Blokhina E, Gnatienko N, Quinn E, Bridden C, Walley AY, Bryant KJ, Lioznov D, Krupitsky E, Samet JH Tags: Addict Sci Clin Pract Source Type: research

Screening in Trauma for Opioid Misuse Prevention (STOMP): study protocol for the development of an opioid risk screening tool for victims of injury.
DISCUSSION: Positive findings from the proposed work would lead to improved, standardized opioid risk screening practices among victims of traumatic injury. The ultimate goal of this and future work is to reduce the likelihood of opioid misuse, addiction, and related complications, such as overdose and death. Trial registration Clinicaltrials.gov registration number: NCT02861976. Date of registration: Feb 9, 2016. PMID: 29198186 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - December 4, 2017 Category: Addiction Authors: Brown R, Deyo B, Riley C, Quanbeck A, Glass JE, Turpin R, Hetzel S, Nicholas C, Cruz M, Agarwal S Tags: Addict Sci Clin Pract Source Type: research

Testing the implementation and sustainment facilitation (ISF) strategy as an effective adjunct to the Addiction Technology Transfer Center (ATTC) strategy: study protocol for a cluster randomized trial.
DISCUSSION: Although not without limitations, the ISF experiment has several strengths: a highly rigorous design (randomized, hypothesis-driven), high-need setting (ASOs), large sample size (39 ASOs), large geographic representation (23 states and the District of Columbia), and testing along multiple phases of the EPIS continuum (preparation, implementation, and sustainment). Thus, study findings will significantly improve generalizable knowledge regarding the best preparation, implementation, and sustainment strategies for advancing EBPs along the EPIS continuum. Moreover, increasing ASO's capacity to address substance us...
Source: Addiction Science and Clinical Practice - November 17, 2017 Category: Addiction Authors: Garner BR, Zehner M, Roosa MR, Martino S, Gotham HJ, Ball EL, Stilen P, Speck K, Vandersloot D, Rieckmann TR, Chaple M, Martin EG, Kaiser D, Ford JH Tags: Addict Sci Clin Pract Source Type: research

Testing the effectiveness of a motivational interviewing-based brief intervention for substance use as an adjunct to usual care in community-based AIDS service organizations: study protocol for a multisite randomized controlled trial.
DISCUSSION: If successfully able to implement MIBI as an effective adjunct to usual care, the current trial may have a significant impact on increasing the capacity of ASOs to address problematic substance use among individuals living with HIV/AIDS. Reducing the prevalence of problematic substance use among individuals living with HIV/AIDS within the United States may lead to significant improvements on key performance measures (i.e., the HIV Care Continuum and the 90-90-90 target). Trial registration ClinicalTrials.gov: NCT02495402. PMID: 29149914 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - November 17, 2017 Category: Addiction Authors: Garner BR, Gotham HJ, Tueller SJ, Ball EL, Kaiser D, Stilen P, Speck K, Vandersloot D, Rieckmann TR, Chaple M, Martin EG, Martino S Tags: Addict Sci Clin Pract Source Type: research

More beds are not the answer: transforming detoxification units into medication induction centers to address the opioid epidemic.
PMID: 29141667 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - November 15, 2017 Category: Addiction Authors: Friedmann PD, Suzuki J Tags: Addict Sci Clin Pract Source Type: research

Factors influencing the long-term sustainment of quality improvements made in addiction treatment facilities: a qualitative study.
CONCLUSIONS: Factors identified in QI frameworks as important for short-term sustainment-organizational capacity (e.g. staffing and leadership) and intervention characteristics (e.g. flexibility and fit)-are also important to long-term sustainment. PMID: 29089054 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - November 1, 2017 Category: Addiction Authors: Stumbo SP, Ford JH, Green CA Tags: Addict Sci Clin Pract Source Type: research

Convenience without disclosure: a formative research study of a proposed integrated methadone and antiretroviral therapy service delivery model in Dar es Salaam, Tanzania.
CONCLUSIONS: An integrated methadone and ART service delivery model at the MNH OTP clinic could improve access to HIV care and treatment for OTP patients. However, specific implementation strategies must ensure that OTP providers are not overburdened and confidentiality of patients is maintained. PMID: 29041950 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - October 18, 2017 Category: Addiction Authors: Cooke A, Saleem H, Mushi D, Mbwambo J, Hassan S, Lambdin BH Tags: Addict Sci Clin Pract Source Type: research

Barriers and facilitators of the HIV care continuum in Southern New England for people with drug or alcohol use and living with HIV/AIDS: perspectives of HIV surveillance experts and service providers.
CONCLUSIONS: The most substantial HCC challenges for PLWH with substance use problems included linking and retaining in treatment those with multiple co-morbidities and meeting their basic living needs. Recommendations to improve HCC outcomes for PLWH with substance use problems include increasing easy access to effective drug and mental health treatment, expanding case management and peer navigation services, training staff about harm reduction, de-stigmatizing, and culturally competent approaches to interacting with patients, and increasing information-sharing and service coordination among service providers and the soci...
Source: Addiction Science and Clinical Practice - October 2, 2017 Category: Addiction Authors: Grau LE, Griffiths-Kundishora A, Heimer R, Hutcheson M, Nunn A, Towey C, Stopka TJ Tags: Addict Sci Clin Pract Source Type: research

Alcohol consumption patterns and HIV viral suppression among persons receiving HIV care in Florida: an observational study.
The objectives of this study were to determine the association of different patterns of alcohol consumption to HIV viral suppression and ART adherence, and to determine whether any associations of alcohol with HIV viral suppression were mediated by poor ART adherence. METHODS: This observational study used baseline data from 619 HIV+ participants, recruited across 8 clinical and community settings across Florida as part of the Florida Cohort from 2014 to 2016. Alcohol consumption was measured by self-report, and grouped into four categories: heavy drinking (>7/week for women or>14 drinks/week for men); bing...
Source: Addiction Science and Clinical Practice - September 27, 2017 Category: Addiction Authors: Cook RL, Zhou Z, Kelso-Chichetto NE, Janelle J, Morano JP, Somboonwit C, Carter W, Ibanez GE, Ennis N, Cook CL, Cohen RA, Brumback B, Bryant K Tags: Addict Sci Clin Pract Source Type: research

Barriers and facilitators to implementing addiction medicine fellowships: a qualitative study with fellows, medical students, residents and preceptors.
CONCLUSIONS: Implementation of addiction medicine fellowships appears feasible, although a number of barriers exist. Research into factors within the local/practice environment that shape delivery of education to ensure consistent and quality education scale-up is a priority. PMID: 28927448 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - September 20, 2017 Category: Addiction Authors: Klimas J, Small W, Ahamad K, Cullen W, Mead A, Rieb L, Wood E, McNeil R Tags: Addict Sci Clin Pract Source Type: research

HIV treatment cascade among female entertainment and sex workers in Cambodia: impact of amphetamine use and an HIV prevention program.
This study aimed to describe the HIV CoC in HIV-positive FESW. We examined CoC outcomes among HIV-positive FESW participating in the Cambodia Integrated HIV and Drug Prevention Implementation (CIPI) study, being implemented in ten provinces. CIPI is a trial aimed at reducing ATS use concomitant with the SMARTgirl HIV prevention program. METHODS: From 2013 to 2016, 1198 FESW ≥ 18 years old who reported multiple sex partners and/or transactional sex were recruited. We identified 88 HIV-positive women at baseline. We described linkage to care as 12-month retention and viral suppression (
Source: Addiction Science and Clinical Practice - September 5, 2017 Category: Addiction Authors: Muth S, Len A, Evans JL, Phou M, Chhit S, Neak Y, Ngak S, Stein ES, Carrico AW, Maher L, Page K Tags: Addict Sci Clin Pract Source Type: research

Integrated HIV care is associated with improved engagement in treatment in an urban methadone clinic.
Abstract BACKGROUND: Persons living with HIV and unhealthy substance use are often less engaged in HIV care, have higher morbidity and mortality and are at increased risk of transmitting HIV to uninfected partners. We developed a quality-improvement tracking system at an urban methadone clinic to monitor patients along the HIV care continuum and identify patients needing intervention. OBJECTIVE: To evaluate patient outcomes along the HIV Care Continuum at an urban methadone clinic and explore the relationship of HIV primary care site and patient demographic characteristics with retention in HIV treatment and ...
Source: Addiction Science and Clinical Practice - August 22, 2017 Category: Addiction Authors: Simeone C, Shapiro B, Lum PJ Tags: Addict Sci Clin Pract Source Type: research

Screening, treatment initiation, and referral for substance use disorders.
Abstract Substance use remains a leading cause of preventable death globally. A model of intervention known as screening, brief intervention, and referral to treatment (SBIRT) was developed decades ago to facilitate time- and resource-sensitive interventions in acute care and outpatient settings. SBIRT, which includes a psychosocial intervention incorporating the principles of motivational interviewing, has been shown to be effective in reducing alcohol consumption and consequences in unhealthy drinkers both in primary care and emergency department settings. Subsequently, SBIRT for unhealthy alcohol use has been e...
Source: Addiction Science and Clinical Practice - August 7, 2017 Category: Addiction Authors: Bernstein SL, D'Onofrio G Tags: Addict Sci Clin Pract Source Type: research

Comparison of DSM-IV and DSM-5 criteria for alcohol use disorders in VA primary care patients with frequent heavy drinking enrolled in a trial.
CONCLUSIONS: In this sample of primary care patients with frequent heavy drinking, DSM-5 identified 13% more patients with AUD than DSM-IV. This group had a lower mental health symptom burden and less self-reported readiness to change compared to those meeting criteria for both DSM-IV and DSM-5 AUD. Trial Registration ClinicalTrials.gov NCT01400581. 2011 February 17. PMID: 28716049 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - July 18, 2017 Category: Addiction Authors: Takahashi T, Lapham G, Chavez LJ, Lee AK, Williams EC, Richards JE, Greenberg D, Rubinsky A, Berger D, Hawkins EJ, Merrill JO, Bradley KA Tags: Addict Sci Clin Pract Source Type: research

Enhancing patient navigation to improve intervention session attendance and viral load suppression of persons with HIV and substance use: a secondary post hoc analysis of the Project HOPE study.
Abstract BACKGROUND: Interventions are needed to improve viral suppression rates among persons with HIV and substance use. A 3-arm randomized multi-site study (Metsch et al. in JAMA 316:156-70, 2016) was conducted to evaluate the effect on HIV outcomes of usual care referral to HIV and substance use services (N = 253) versus patient navigation delivered alone (PN: N = 266) or together with contingency management (PN + CM; N = 271) that provided financial incentives targeting potential behavioral mediators of viral load suppression. AIMS: This secondary analysis evaluate...
Source: Addiction Science and Clinical Practice - June 27, 2017 Category: Addiction Authors: Stitzer M, Matheson T, Cunningham C, Sorensen JL, Feaster DJ, Gooden L, Hammond AS, Fitzsimons H, Metsch LR Tags: Addict Sci Clin Pract Source Type: research

Associations of criminal justice and substance use treatment involvement with HIV/HCV testing and the HIV treatment cascade among people who use drugs in Oakland, California.
Abstract BACKGROUND: People who smoke crack cocaine and people who inject drugs are at-risk for criminal justice involvement as well as HIV and HCV infection. Compared to criminal justice involvement, substance use treatment (SUT) can be cost-effective in reducing drug use and its associated health and social costs. We conducted a cross-sectional study of people who smoke crack cocaine and people who inject drugs to examine the association between incarceration, community supervision and substance use treatment with HIV/HCV testing, components of the HIV treatment cascade, social and physical vulnerability and ris...
Source: Addiction Science and Clinical Practice - June 14, 2017 Category: Addiction Authors: Lambdin BH, Kral AH, Comfort M, Lopez AM, Lorvick J Tags: Addict Sci Clin Pract Source Type: research

Patient-centered primary care for adults at high risk for AUDs: the Choosing Healthier Drinking Options In primary CarE (CHOICE) trial.
CONCLUSION: The CHOICE trial tested a patient-centered intervention for AUDs and recruited primary care patients at high risk for AUDs, with a spectrum of severity, co-morbidity, and readiness to change drinking. Trial registration The trial is registered at clinicaltrial.gov (NCT01400581). PMID: 28514963 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - May 17, 2017 Category: Addiction Authors: Bradley KA, Ludman EJ, Chavez LJ, Bobb JF, Ruedebusch SJ, Achtmeyer CE, Merrill JO, Saxon AJ, Caldeiro RM, Greenberg DM, Lee AK, Richards JE, Thomas RM, Matson TE, Williams EC, Hawkins E, Lapham G, Kivlahan DR Tags: Addict Sci Clin Pract Source Type: research

Rethinking alcohol interventions in health care: a thematic meeting of the International Network on Brief Interventions for Alcohol & Other Drugs (INEBRIA).
This report summarizes practice, research, and policy recommendations and key research developments from our meeting. In order to move the field forward, a research agenda was proposed to (1) address evidence gaps in screening, brief intervention, and referral to treatment, (2) develop innovations to address severe unhealthy alcohol use within primary care, (3) describe the stigma of unhealthy alcohol use, which obstructs progress in prevention and treatment, (4) reconsider existing conceptualizations of unhealthy alcohol use that may influence health care, and (5) identify efforts needed to improve the capacity for addres...
Source: Addiction Science and Clinical Practice - May 10, 2017 Category: Addiction Authors: Glass JE, Andréasson S, Bradley KA, Finn SW, Williams EC, Bakshi AS, Gual A, Heather N, Sainz MT, Benegal V, Saitz R Tags: Addict Sci Clin Pract Source Type: research

Acceptability of a mobile health intervention to enhance HIV care coordination for patients with substance use disorders.
CONCLUSIONS: Peer health navigation and smartphone-based EMA are acceptable approaches to facilitating engagement in HIV care for drug using populations. Future studies to evaluate the efficacy of this approach for improving long-term retention in care and antiretroviral treatment outcomes are warranted. ClinicalTrials.gov Identifier NCT01941108; registered on September 4, 2013. PMID: 28441962 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - April 26, 2017 Category: Addiction Authors: Westergaard RP, Genz A, Panico K, Surkan PJ, Keruly J, Hutton HE, Chang LW, Kirk GD Tags: Addict Sci Clin Pract Source Type: research

Seek, test, treat: substance-using women in the HIV treatment cascade in South Africa.
CONCLUSIONS: These results, although cross-sectional, provide some guidance for provincial authorities to address barriers to HIV care for sexually active, substance-using vulnerable women in Pretoria. Targeting the inner city with prevention campaigns, expanding and improving substance abuse treatment programs, linking clients with simultaneous HIV testing and treatment, and targeting women who have experienced sexual assault and violence may help the government achieve the UNAIDS 90-90-90 treatment target. Clinical Trials.gov NCT01497405 registered on December 1, 2011. PMID: 28441975 [PubMed - in process] (Source: A...
Source: Addiction Science and Clinical Practice - April 26, 2017 Category: Addiction Authors: Wechsberg WM, van der Horst C, Ndirangu J, Doherty IA, Kline T, Browne FA, Belus JM, Nance R, Zule WA Tags: Addict Sci Clin Pract Source Type: research

VA residential substance use disorder treatment program providers' perceptions of facilitators and barriers to performance on pre-admission processes.
CONCLUSIONS: Metrics for pre-admission processes can be helpful for monitoring residential SUD treatment programs. Interviewing program management and staff about drivers of performance metrics can play a complementary role by identifying innovative and other strong practices, as well as high-value targets for quality improvement. Key facilitators of high-performing facilities may offer programs with lower performance useful strategies to improve specific pre-admission processes. PMID: 28372579 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - April 4, 2017 Category: Addiction Authors: Ellerbe LS, Manfredi L, Gupta S, Phelps TE, Bowe TR, Rubinsky AD, Burden JL, Harris AH Tags: Addict Sci Clin Pract Source Type: research

The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy.
CONCLUSION: Our study demonstrates that the younger one begins to use opioids, the greater their chance of having a physical or psychiatric co-morbidity. Understanding the risk posed by an earlier onset of opioid use for the later development of comorbid disorders informs clinical practice about important prognostic predictors and aids in the identification of high-risk patients. PMID: 28347350 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 28, 2017 Category: Addiction Authors: Naji L, Dennis BB, Bawor M, Varenbut M, Daiter J, Plater C, Pare G, Marsh DC, Worster A, Desai D, MacKillop J, Thabane L, Samaan Z Tags: Addict Sci Clin Pract Source Type: research

Mobile technology intervention to improve care coordination between HIV and substance use treatment providers: development, training, and evaluation protocol.
This study will develop and evaluate a CCI consisting of a tablet-based mobile platform for treatment providers, an interagency communication protocol, and a training protocol as a means of improving the integration of care for PLWH who have a SUD. Results have the potential to advance the field by bridging gaps in a fragmented healthcare system, and improving treatment efficiency, work flow, and communication among interdisciplinary providers from different treatment settings. TRIAL REGISTRATION: NCT02906215. PMID: 28288678 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - March 13, 2017 Category: Addiction Authors: Claborn K, Becker S, Ramsey S, Rich J, Friedmann PD Tags: Addict Sci Clin Pract Source Type: research

Public sector low threshold office-based buprenorphine treatment: outcomes at year 7.
CONCLUSIONS: Unobserved "home" buprenorphine induction in a public sector primary care setting appeared a feasible and safe clinical practice. Post-induction treatment retention of a median 38 weeks was in line with previous naturalistic studies of real-world office-based opioid treatment. Low threshold treatment protocols, as compared to national guidelines, may compliment recently increased prescriber patient limits and expand access to buprenorphine among public sector opioid use disorder patients. PMID: 28245872 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - February 27, 2017 Category: Addiction Authors: Bhatraju EP, Grossman E, Tofighi B, McNeely J, DiRocco D, Flannery M, Garment A, Goldfeld K, Gourevitch MN, Lee JD Tags: Addict Sci Clin Pract Source Type: research

A systematic review of health economic models of opioid agonist therapies in maintenance treatment of non-prescription opioid dependence.
CONCLUSION: A relatively small number of studies of varying quality were found. Strengths and weaknesses relating to model structure, inputs and approach were identified across all the studies. There was no indication of a single standard emerging as a preferred approach. Most studies omitted societal costs, an important issue since the implications of drug abuse extend widely beyond healthcare services. Nevertheless, elements from previous models could together form a framework for future economic evaluations in opioid agonist therapy including all relevant costs and outcomes. This could more adequately support decision-m...
Source: Addiction Science and Clinical Practice - February 23, 2017 Category: Addiction Authors: Chetty M, Kenworthy JJ, Langham S, Walker A, Dunlop WC Tags: Addict Sci Clin Pract Source Type: research

Prenatal treatment for opioid dependency: observations from a large inner-city clinic.
CONCLUSIONS: The number of mother-infant pairs increased significantly from 2006 to 2010 and the clinical characteristics of these patients changed over time. Our experience reflects the rising increase in opioid use disorders in pregnancy and NAS, mandating the need for expansion of comprehensive prenatal care options for these women and their children. PMID: 28086944 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - January 12, 2017 Category: Addiction Authors: Saia K, Bagley SM, Wachman EM, Patel PP, Nadas MD, Brogly SB Tags: Addict Sci Clin Pract Source Type: research

Opioid overdose prevention and naloxone rescue kits: what we know and what we don't know.
This article summarizes the known benefits of naloxone access and details unanswered questions about overdose education and naloxone rescue kits. Hopefully future research will address these knowledge gaps, improve the effectiveness of opioid overdose education and naloxone distribution programs, and unlock the full promise of naloxone rescue kits. PMID: 28061909 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - January 6, 2017 Category: Addiction Authors: Kerensky T, Walley AY Tags: Addict Sci Clin Pract Source Type: research

Prevalence and factors associated with use of khat: a survey of patients entering HIV treatment programs in Ethiopia.
CONCLUSIONS: Khat use was common among HIV patients entering care, and associated with symptoms of poorer physical health. Over half started khat use when they were young. Although most believed khat is harmful for HIV patients, a number of respondents reported some difficulty controlling their drug use. In settings where khat is legal and widely utilized, developing interventions for responsible use represent an important health priority as part of comprehensive care for people living with HIV. PMID: 28057079 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - January 5, 2017 Category: Addiction Authors: Lifson AR, Workneh S, Shenie T, Ayana DA, Melaku Z, Bezabih L, Waktola HT, Dagne B, Hilk R, Winters KC, Slater L Tags: Addict Sci Clin Pract Source Type: research

Validation of the AUDIT-C in adults seeking help with their drinking online.
CONCLUSIONS: AUDIT-C cut-off scores for identifying alcohol consumption above weekly limits in this largely UK based study population were substantially higher than those reported in other validation studies. Researchers and practitioners should select AUDIT-C cut-off scores according to the purpose of identifying risky drinkers and hence the relative importance of sensitivity and/or specificity. PMID: 28049515 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - January 3, 2017 Category: Addiction Authors: Khadjesari Z, White IR, McCambridge J, Marston L, Wallace P, Godfrey C, Murray E Tags: Addict Sci Clin Pract Source Type: research

Technology-assisted intervention for parents of adolescents in residential substance use treatment: protocol of an open trial and pilot randomized trial.
This study will adapt and evaluate a technology-assisted parenting intervention as a means of improving adolescent outcomes following residential SUD treatment. Results have the potential to advance the field by: addressing a high-risk population, improving parental engagement; targeting parenting practices (putative mediators of change) that have been linked to adolescent outcomes; and developing a highly disseminable approach. PMID: 28049542 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - January 2, 2017 Category: Addiction Authors: Becker SJ, Hernandez L, Spirito A, Conrad S Tags: Addict Sci Clin Pract Source Type: research

Alcohol use in opioid agonist treatment.
Abstract Alcohol misuse among individuals receiving agonist treatment for an opioid use disorder is common and is associated with significant morbidity and mortality. At present, though substantial research highlights effective strategies for the screening, diagnosis and management of an alcohol or opioid use disorder individually, less is known about how best to care for those with a dual diagnosis especially since common treatments for opioid addiction may be contraindicated in a setting of alcohol use. This review summarizes existing research and characterizes the prevalence, clinical implications and managemen...
Source: Addiction Science and Clinical Practice - December 7, 2016 Category: Addiction Authors: Nolan S, Klimas J, Wood E Tags: Addict Sci Clin Pract Source Type: research

Emerging adults in substance misuse intervention: preintervention characteristics and responses to a motivation-enhancing program.
CONCLUSIONS: Findings showed positive changes during intervention for many emerging adult participants attending PFL. Further research is needed that include comparison conditions, as well as examine longer-term outcomes in this population. PMID: 27829442 [PubMed - in process] (Source: Addiction Science and Clinical Practice)
Source: Addiction Science and Clinical Practice - November 8, 2016 Category: Addiction Authors: Beadnell B, Crisafulli MA, Stafford PA, Casey EA Tags: Addict Sci Clin Pract Source Type: research