Multicenter comparative study on the usefulness of the optimal electrosurgical unit setting in endoscopic papillectomy for ampullary neoplasms (with video)
ConclusionsThe risks of pancreatitis and residual lesions after EP may be lower when the VIO electrosurgical unit is used with the optimal setting. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - April 25, 2024 Category: Gastroenterology Authors: Kenjiro Yamamoto,
Takao Itoi,
Akio Katanuma,
Tatsuya Ishii,
Eisuke Iwasaki,
Shintaro Kawasaki,
Takayoshi Tsuchiya,
Ryosuke Tonozuka,
Kazumasa Nagai,
Shuntaro Mukai Tags: ORIGINAL ARTICLE Source Type: research
Prediction of physicochemical and pharmacokinetic properties of botanical constituents by computational models
This study sought to use computational (i.e., in silico) models, including quantitative structure –activity relationships (QSAR) and physiologically based pharmacokinetic (PBPK) modeling, to predict properties of botanical constituents. One hundred and three major constituents (e.g., withanolides, mitragynine, and yohimbine) in 13 botanicals (e.g., ashwagandha, kratom, and yohimbe) were invest igated. The predicted properties included biopharmaceutical classification system (BCS) classes based on aqueous solubility and permeability, oral absorption, liver microsomal clearance, oral bioavailability, and others. Over half ...
Source: Journal of Applied Toxicology - April 25, 2024 Category: Toxicology Authors: Yitong Liu,
Michael Lawless,
Miao Li,
Kiara Fairman,
Michelle R. Embry,
Constance A. Mitchell Tags: RESEARCH ARTICLE Source Type: research
The Relationship between Diet, Gut Mycobiome, and Functional Gastrointestinal Disorders: Evidence, Doubts, and Prospects
Dietary ingredients and patterns have the potential to regulate the structure of gut fungi. The relationship between mycobiome and diet may have important implications for the pathogenesis of funcitonal gastrointestinal disorders (FGIDs). AbstractGut fungi are important parts of intestinal microbes. Dietary ingredients have the potential to regulate the structure of gut fungi in different directions and modulate mycobiome composition by changing dietary patterns, which have been applied to neurological disorders. Emerging pieces of evidence have revealed the regulatory functions of gut mycobiome in gastrointestinal disease...
Source: Molecular Nutrition and Food Research - April 25, 2024 Category: Food Science Authors: Tianxu Liu,
Ismail Muhammad Asif,
Yan Chen,
Meixue Zhang,
Bin Li,
Ling Wang Tags: Review Source Type: research
A prevalence study on gastrointestinal parasitic infections of pig (Sus scrofa) in and around Meerut, Western Uttar Pradesh, India
AbstractThe present study was conducted to record the prevalence of gastrointestinal parasites of pigs by faecal sample examination. Faecal samples were collected in three different seasons viz; monsoon, post monsoon and pre monsoon, from in and around Meerut district of Western Uttar Pradesh. A total of 642 faecal samples were collected for a period of one year (2020 –21). The overall prevalence rate recorded for gastrointestinal parasites in pigs was 64.4%.The findings of the present work showed that seasons have a significant role on the prevalence of gastrointestinal parasites infection in pigs, with highest prevalen...
Source: Journal of Parasitic Diseases - April 25, 2024 Category: Parasitology Source Type: research
Therapeutic Hypothermia Compared with Normothermia in Adults with Traumatic Brain Injury; Functional Outcome, Mortality, and Adverse Effects: A Systematic Review and Meta-Analysis
ConclusionsWith the addition of several recent randomized clinical trials and a thorough quality assessment, we have provided an updated systematic review and meta-analysis that concludes that TH does not show any benefit over normothermia in terms of mortality and functional outcome. (Source: Neurocritical Care)
Source: Neurocritical Care - April 25, 2024 Category: Neurology Source Type: research
Recurrent splanchnic and extrasplanchnic thrombotic events in patients with non-cirrhotic portal vein thrombosis associated with local factors
Lay summaryThis retrospective large serie of recent noncirrhotic portal vein thrombosis associated with local factors highlights that prothrombotic factors with high-risk of thrombosis identified in one-third of cases were highly associated with a risk of new thrombotic events. Recanalization and permanent anticoagulation prevented the risk of rethrombosis. (Source: Journal of Hepatology)
Source: Journal of Hepatology - April 25, 2024 Category: Gastroenterology Authors: Isabelle Ollivier-Hourmand, Louise Lebedel, Berta Bartroli Alabau, Odile Goria, Christophe Bureau, J érome Dumortier, Alexandra Heurgué, Christine Silvain, Victor De-Ledinghen, Pierre-Emmanuel Rautou, Audrey Payancé, Teresa García Ballester, Edilmar A Tags: Research Article Source Type: research
Effects of Exercise Training on Muscle Mass and Physical Function in Patients with Hepatocellular Carcinoma After Diagnosis: A Systematic Review
ConclusionTogether, the results suggest that patients may benefit from physical exercise training after treatment to improve muscle mass and physical function. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Development and Validation of a Colorectal Cancer Prediction Model: A Nationwide Cohort-Based Study
ConclusionsWe developed an individualized risk prediction model for CRC that can be utilized as a complementary decision support tool for healthcare providers to precisely identify subjects at high risk for CRC and refer them for confirmatory testing. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Patients with Celiac Disease Have High Prevalence of Fatty Liver and Metabolic Syndrome
ConclusionsPatients with CeD have a high prevalence of fatty liver and metabolic syndrome which increases further with the initiation of GFD. Patients with CeD should thus be screened and monitored for development of fatty liver and metabolic syndrome. They should be counselled appropriately regarding their diet and inclusion of physical activity in their lifestyle.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Effectiveness of Strategy-Focused Training in Colorectal Endoscopic Submucosal Dissection: A Retrospective Observational Study
Conclusion“Strategy-focused” ESD training consistently yields successful outcomes, effectively adapting to varying difficulty factors in different proficient stages. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
A Novel lncRNA lncRNA-4045 Promotes the Progression of Hepatocellular Carcinoma by Affecting the Expression of AKR1B10
ConclusionLncRNA-4045 may promote HCC via enhancement of the expression of AKR1B10 protein. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Endoscopic Removal of an Obstructing Fecolith at the Entrance of Appendix
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Efficacy of Endoscopic Tissue Adhesive in Patients with Gastrointestinal Tumor Bleeding
ConclusionETA demonstrated excellent immediate hemostasis success rate in GITB cases and showed promising outcomes in prevention re-bleeding. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Coffee, Alcohol, and Artificial Sweeteners Have Temporal Associations with Gastrointestinal Symptoms
ConclusionsCoffee, alcohol, and artificial sweeteners were associated with GI symptoms in this large IBS-predominant sample. Symptom onset is often within 2 h postprandial, but some foods were associated with a delayed response, possibly an important consideration in implementing dietary recommendations. Clinical trials must test the causality of the demonstrated food–symptom associations. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Imaging-based diagnosis of sarcopenia for transplant-free survival in primary sclerosing cholangitis
Imaging-based assessment of sarcopenia is a well-validated prognostic tool for patients with chronic liver disease. However, little is known about its value in patients with primary sclerosing cholangitis (PSC... (Source: BMC Gastroenterology)
Source: BMC Gastroenterology - April 25, 2024 Category: Gastroenterology Authors: Pedram Keshoofi, Philipp Schindler, Florian Rennebaum, Friederike Cordes, Haluk Morgul, Moritz Wildgruber, Hauke S. Heinzow, Andreas Pascher, Hartmut H. Schmidt, Anna H üsing-Kabar, Michael Praktiknjo, Jonel Trebicka and Leon Louis Seifert Tags: Research Source Type: research
