A PAX3 insertion in the Celestial breed and certain feline breeding lines with dominant blue eyes
Anim Genet. 2024 Apr 22. doi: 10.1111/age.13433. Online ahead of print.ABSTRACTDuring the last 60 years many inherited traits in domestic outbred cats were selected and retained giving birth to new breeds characterised by singular coat or morphological phenotypes. Among them, minimal white spotting associated with blue eyes was selected by feline breeders to create the Altai, Topaz, and Celestial breeds. Various established breeds also introduced this trait in their lineages. The trait, that was confirmed as autosomal dominant by breeding data, was first described in domestic cats from Kazakhstan and Russia, in British sho...
Source: Animal Genetics - April 22, 2024 Category: Genetics & Stem Cells Authors: Marie Abitbol Alice Couronn é Caroline Dufaure de Citres Vincent Gache Source Type: research
Inferential Comprehension Abilities in French-Speaking Preschoolers Exposed to Neglect in the Early Longitudinal Language and Neglect Study
CONCLUSIONS: This study demonstrates the significant gap in inferential comprehension abilities between neglected and non-neglected preschool children. These results reiterate the importance of early detection of language comprehension difficulties in young children coming from vulnerable environments.PMID:38648562 | DOI:10.1044/2024_JSLHR-23-00484 (Source: Journal of speech, language, and hearing research : JSLHR)
Source: Journal of speech, language, and hearing research : JSLHR - April 22, 2024 Category: Speech-Language Pathology Authors: Pamela Filiatrault-Veilleux Chantal Desmarais Caroline Bouchard Breanne Esau Audette Sylvestre Source Type: research
Assessment of health literacy in a French emergency department
Health literacy (HL) has become a subject of major interest in public health worldwide. It is known to be linked to self-efficacy in care use and to global health status, and a non-negligible frequency of prob... (Source: BMC Health Services Research)
Source: BMC Health Services Research - April 22, 2024 Category: General Medicine Authors: Pauline Marie, Nicolas Romain-Scelle, Veronique Potinet, Anne Marie Schott and Marion Douplat Tags: Research Source Type: research
Opportunistic screening in the emergency department
Smoking cessation is currently topical with recent government announcements regarding restricting the sale of disposable vapes and a consultation on raising the legal age of buying tobacco from 18 years, so that anyone born after a certain year will never be able to buy cigarettes legally. This edition of the EMJ contains a randomised controlled multicentre trial of smoking cessation initiated in the emergency department (ED).1 The intervention group received brief smoking cessation advice as well as provision of an e-cigarette starter kit and referral to the local stop smoking services, while the control group received ad...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: France, J. Tags: Commentary Source Type: research
Understanding RCEM Best Practice Guidelines
Royal College of Emergency Medicine (RCEM) Best Practice Guidelines are produced by a variety of special interest groups or convened expert advisory groups which sit under the umbrella of the College’s Quality in Emergency Care Committee (QECC).1 They are produced to bridge the gap between systematically derived evidence-based recommendations and the need for emergency clinicians to provide quality care and advice to patients, or to respond to evolving trends. Unlike National Institute for Health and Care Excellence (NICE) guidelines, which are costly to produce, incorporate calls for evidence, formal evidence search...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Humphries, C., Boyle, A. A., France, J., Hunt, P. Tags: Commentary Source Type: research
Photocoagulation or sham laser in addition to conventional anti-VEGF therapy in macular edema associated with TelCaps due to diabetic macular edema or retinal vein occlusion (TalaDME): a study protocol for a multicentric, French, two-group, non-commercial, active-control, observer-masked, non-inferiority, randomized controlled clinical trial
Macular edema (ME) results from hyperpermeability of retinal vessels, leading to chronic extravasation of plasma components into the retina and hence potentially severe visual acuity loss. Current standard of ... (Source: Trials)
Source: Trials - April 22, 2024 Category: General Medicine Authors: B énédicte Dupas, Daniela Castro-Farias, Jean-François Girmens, Ali Eginay, Aude Couturier, Frederic Villeroy, Marie-Noëlle Delyfer, Catherine Creuzot-Garcher, Audrey Giocanti-Auregan, Laurence Béral, Carl Arndt, Charles Mesnard, Eric Vicaut, Philipp Tags: Study protocol Source Type: research
Reporting of interventional clinical trial results in an academic center: a survey of completed studies
The dissemination of clinical trial results is an important scientific and ethical endeavour. This survey of completed interventional studies in a French academic center describes their reporting status. (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - April 22, 2024 Category: Research Authors: Anne Sophie Alix-Doucet, Constant Vinatier, Lo ïc Fin, Hervé Léna, Hélène Rangé, Clara Locher and Florian Naudet Tags: Research Source Type: research
Are the 7C psychological antecedents associated with COVID-19 vaccine behaviours beyond intentions? A cross-sectional study on at-least-one-dose and up-to-date vaccination status, and uptake speed among adults in France
CONCLUSION: This study demonstrates that the 7C not only explain vaccine intention, but also vaccine behaviours, and underpins the importance of developing vaccine promotion strategies considering the 7C antecedents.PMID:38643038 | DOI:10.1016/j.vaccine.2024.04.024 (Source: Vaccine)
Source: Vaccine - April 20, 2024 Category: Allergy & Immunology Authors: Ga ëlle Lièvre Jonathan Sicsic Simon Galmiche Tiffany Charmet Arnaud Fontanet Judith E Mueller Source Type: research
Transthyretin amyloid polyneuropathy in France: A cross-sectional study with 413 patients and real-world tafamidis meglumine use (2009-2019)
CONCLUSION: In France, ATTRv patients are usually identified early thanks to the national network and the help of diagnosis combining genetic testing and mini-invasive biopsies.PMID:38643028 | DOI:10.1016/j.neurol.2024.02.393 (Source: Revue Neurologique)
Source: Revue Neurologique - April 20, 2024 Category: Neurology Authors: D Adams P Cintas G Sol é C Tard C Labeyrie A Echaniz-Laguna C Cauquil Y Pereon L Magy R Juntas Morales J C Antoine E Lagrange P Petiot M Mallaret B Francou A Guiochon-Mantel A Coste O Demarcq C Geffroy V Famelart J Rudant M Bartoli E Donal O Lairez J C E Source Type: research
Systematic analysis of evaluations of Objective Structured Clinical Exam (OSCE) multiple circuits: Explanatory variables and inter-rater correlations
CONCLUSION: This first study on the variability of OSCE circuit scores in France shows good reproducibility with influence of station characteristics. In order to standardize circuits, variability linked to the domain competency should be considered as well.PMID:38643040 | DOI:10.1016/j.revmed.2024.03.013 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - April 20, 2024 Category: Internal Medicine Authors: E Ollier C Pelissier C Boissier T Barjat P Berthelot C Boutet X Gocko C Le Hello S Perinel Source Type: research
Transthyretin amyloid polyneuropathy in France: A cross-sectional study with 413 patients and real-world tafamidis meglumine use (2009-2019)
CONCLUSION: In France, ATTRv patients are usually identified early thanks to the national network and the help of diagnosis combining genetic testing and mini-invasive biopsies.PMID:38643028 | DOI:10.1016/j.neurol.2024.02.393 (Source: Revue Neurologique)
Source: Revue Neurologique - April 20, 2024 Category: Neurology Authors: D Adams P Cintas G Sol é C Tard C Labeyrie A Echaniz-Laguna C Cauquil Y Pereon L Magy R Juntas Morales J C Antoine E Lagrange P Petiot M Mallaret B Francou A Guiochon-Mantel A Coste O Demarcq C Geffroy V Famelart J Rudant M Bartoli E Donal O Lairez J C E Source Type: research
Clinical impact of an individualised clinical pharmacy programme into the memory care pathway of older people: an observational study
ConclusionThe integration of clinical pharmacist secured the Memory care pathway of older patients with a cognitive complaint by identifying an important number of DRPs and PIMs with potential cognitive iatrogenic risk. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - April 20, 2024 Category: Drugs & Pharmacology Source Type: research
Basal Insulinotherapy in Patients Living with Diabetes in France: The EF-BI Study
ConclusionUse of Gla-300 resulted in a better persistence, less acute hospitalized events at least in T2DM, and reduced healthcare expenditure. These real-life results confirmed the potential interest of using Gla-300 rather than Gla-100. (Source: Diabetes Therapy)
Source: Diabetes Therapy - April 20, 2024 Category: Endocrinology Source Type: research
Impact of Early Access Reform on Oncology Innovation in France: Approvals, Patients, and Costs
ConclusionThe French EA reform contributed to enabling rapid access to innovations in a wide range of indications for oncology patients. However, the findings highlight ongoing challenges in financial sustainability, warranting continued evaluation and adjustments. (Source: BioDrugs)
Source: BioDrugs - April 20, 2024 Category: Drugs & Pharmacology Source Type: research
Basal Insulinotherapy in Patients Living with Diabetes in France: The EF-BI Study
ConclusionUse of Gla-300 resulted in a better persistence, less acute hospitalized events at least in T2DM, and reduced healthcare expenditure. These real-life results confirmed the potential interest of using Gla-300 rather than Gla-100. (Source: Diabetes Therapy)
Source: Diabetes Therapy - April 20, 2024 Category: Endocrinology Source Type: research
