[A scalp lesion].
Authors: Hinschberger O, Bernier C, Damour AS, Oudeville P, Kieffer P PMID: 32456788 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - May 29, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Gynecological Lemierre's syndrome: A case report and literature review].
CONCLUSION: Gynecological Lemierre's syndrome is a rare and unrecognized condition, which could be lethal. Early recognition of the disorder enables initiation of appropriate antibiotic therapy for 4 to 6 weeks, and discussion of anticoagulant therapy which indications are not yet well defined. PMID: 32371121 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - May 7, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Fatal intracerebral hemorrhage in a patient with chronic neutrophilic leukemia: About one case and literature review].
CONCLUSION: This bleeding phenotype has been reported several times in patients with CNL. However, the pathophysiological mechanisms that cause bleeding are not yet fully understood. PMID: 32362366 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - May 6, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Weight loss and cervical mass in a 50  year-old man].
[Weight loss and cervical mass in a 50 year-old man]. Rev Med Interne. 2020 Apr 30;: Authors: Sotier M, Stern JB, Brian E, Wyplosz B, Validire P, Lenoir S, Gayraud M, Cosserat J, Deroux A PMID: 32362367 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - May 6, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Des v ésicules cutanées.
Des vésicules cutanées. Rev Med Interne. 2020 Apr 28;: Authors: Martiano M, Chantalat L, Simon M, Fourgeaud C, Vignes S PMID: 32359817 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - May 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Introduction to debriefing for internists: how to transform real or simulated clinical situations into learning moments].
Authors: Galland J, Jaffrelot M, Sanges S, Fournier JP, Jouquan J, Chiniara G, Rivière É Abstract Debriefing is a phase of synthesis and reflection that immediately follows a real-life or simulated situation. It is an essential educational step that forces the learners to reflect upon the thought processes that underlie their actions. Debriefing encourages a personal and collective reflection in order to remodel erroneous mental schemas and rectify actions done in context. Debriefing cannot be improvised; it requires a sound structure and regular practice in order to be truly effective. The debriefer ...
Source: Revue de Medecine Interne - May 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A tularemia mimicking lymphoma].
CONCLUSION: The association of fever, night sweats, altered general state and mediastinal adenopathies should be considered as a diagnosis of tularemia. Ganglionic biopsy, combined with molecular biology techniques and serology, can confirm the diagnosis. PMID: 32359978 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - May 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Lower-limb peripheral arterial disease in 2019].
Authors: Le Hello C, Fouillet L, Boulon C, Rivière S, El Jaouhari A, Seffert B, Morel A, Boissier C Abstract Peripheral arterial disease is a result of atheroma. This disease is frequent in subjects with vascular risk factors. This disease is also frequent in low income countries. The detection and the diagnosis of peripheral arterial disease is obtained by calculating the ankle brachial index. Patients with peripheral arterial disease are not always symptomatic thus explaining how this disease is under diagnosed. The symptoms can be absent, and especially in case of diabetes or in women. In case of peripher...
Source: Revue de Medecine Interne - May 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Illnesses unrelated to systemic sclerosis (IUSS) diagnosed throughout the patient's follow-up in a referral center: A cohort of 200 patients].
CONCLUSION: This study focused on IUSS in SSc patients and highlights the need for a polyvalent clinical approach all along the follow up of SSc patients. PMID: 32354573 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - May 3, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Thoracic air bubbles of unusual cause].
Authors: Rousset S, Heylen M, Bonnet-Bellon M, Vedel B, Quesnel B, Billet S, Combres B, Henry C PMID: 32354574 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - May 3, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

La m édecine interne dans la pandémie à SARS-CoV-2.
La médecine interne dans la pandémie à SARS-CoV-2. Rev Med Interne. 2020 Apr 17;: Authors: Jamilloux Y, Lega JC PMID: 32334859 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - April 27, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

La recherche clinique à partir d’entrepôts de données. L’expérience de l’Assistance Publique – Hôpitaux de Paris (AP–HP) à l’épreuve de la pandémie de Covid-19.
La recherche clinique à partir d’entrepôts de données. L’expérience de l’Assistance Publique – Hôpitaux de Paris (AP–HP) à l’épreuve de la pandémie de Covid-19. Rev Med Interne. 2020 Apr 17;: Authors: Daniel C PMID: 32334860 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - April 27, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A rare cause of impaired general condition: Muscular and cardiac toxicity of antimalarials].
CONCLUSION: Cardiac and muscular toxicity related to antimalarials are rare and sometimes fatal; thus, they must be systematically assessed in a patient with several years of exposure. A muscle biopsy could be sufficient to allow for the diagnosis. PMID: 32334861 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - April 27, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[COVID-19: Clinical, biological and radiological characteristics in adults, infants and pregnant women. An up-to-date review at the heart of the pandemic].
Authors: Plaçais L, Richier Q Abstract The spread of the new coronavirus SARS-CoV-2, discovered in China in January 2020, led to a pandemic as early as March 2020, forcing every health care system in the affected countries to adapt quickly. In order to better address this major health crisis, which has given rise to numerous scientific publications, we have synthesized the main original clinical studies to facilitate the day-to-day management of patients with COVID-19. We detail the early signs and progression of the disease as well as the different clinical forms, including extra-pulmonary, as known at the ...
Source: Revue de Medecine Interne - April 27, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Is screening for lung cancer in high-risk subjects using low-dose CT scan effective in reducing mortality?]
Authors: Lanthier L, Bouchard N, Huard G, Plourde ME, Cauchon M PMID: 32312589 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - April 23, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Gout].
Authors: Scuiller A, Pascart T, Bernard A, Oehler E Abstract Gout is a chronic disease due to the deposition of monosodium urate microcrystals in joints and tissues. Its incidence and prevalence are increasing worldwide in close relation with the epidemic of obesity and metabolic syndrome. Gout is related to chronic hyperuricemia that should be treated to ensure the reduction or even the disappearance of acute attacks ("gout flares") and to reduce the size and number of tophi. If arthritis of the first metatarsophalangeal joint is the most typical form, other joints may be affected, including the spine. D...
Source: Revue de Medecine Interne - March 25, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Severe MDA5 dermatomyositis associated with cancer and controlled by JAK inhibitor].
We report the case of a 60-year-old woman referred to our hospital for an anti-melanoma differentiation-associated 5 gene antibody-positive dermatomyositis (MDA5 DM) with rapidly progressive interstitial pneumonia, typical cutaneous features and muscular impairment. Treatment with high-dose methylprednisolone, cyclophosphamide and gamma globulin was performed, but the patient remained corticodependant. Blood detection of positive interferon signature justified the administration of an anti-JAK1/2, leading to the clinical remission and the regression of the interferon signature. After 12 months of follow up, a small cell ca...
Source: Revue de Medecine Interne - March 21, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Basal ganglia calcification].
Authors: Auffray-Calvier E, Lintia-Gaultier A, Bourcier R, Aguilar Garcia J Abstract Calcifications of the basal ganglia are frequently seen on the cerebral CT scans and particularly in the globus pallidus. Their frequency increases physiologically with age after 50 years old. However, pathological processes can also be associated with calcium deposits in the gray nuclei, posterior fossa or white matter. Unilateral calcification is often related to an acquired origin whereas bilateral ones are mostly linked to an acquired or genetic origin that will be sought after eliminating a perturbation of phosphocalcic m...
Source: Revue de Medecine Interne - March 15, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[White matter hyper-intensities in ageing: Pathophysiology, associated cognitive disorders and prevention].
Authors: Garnier-Crussard A, Desestret V, Cotton F, Chételat G, Krolak-Salmon P Abstract White matter hyper-intensities (WMH), also known as leukoaraïosis are very common neuroradiological manifestations in the elderly. The main risk factors for WMH are age and high blood pressure. The vascular origin of these lesions is classically accepted and WMH are considered as one feature of the small vessel disease. WMH may be associated with clinical symptoms, depending notably on their importance according to age. They are associated with increased mortality, strokes and changes in cognition with a higher risk...
Source: Revue de Medecine Interne - March 5, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Do have patients with "Hashimoto disease" to be operated on? A critical reading of The Norvegian Trial Surgery Study, a prospective randomized investigation published in Annals of Internal Medicine (2019)].
[Do have patients with "Hashimoto disease" to be operated on? A critical reading of The Norvegian Trial Surgery Study, a prospective randomized investigation published in Annals of Internal Medicine (2019)]. Rev Med Interne. 2020 Feb 26;: Authors: Wémeau JL PMID: 32113635 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - March 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Use of targeting therapy in Erdheim-Chester disease: A case report with neurologic involvement].
CONCLUSION: Our case report shows the persistent diagnostic difficulty of the ECD and the particular gravity of neurologic involvement. PMID: 32113636 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - March 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Infectious myositis].
Authors: Molina B, Pogossian A, De Moreuil C, Rouvière B, Le Berre R Abstract Infectious myositis is a rare condition that can be caused by bacteria, viruses, parasites or fungi. Muscle pain or weakness are symptoms shared by all type of myositis. Diagnosis is made on clinical presentation: fever and poor general state is found in bacterial myositis, diffuse muscle pain with flu-like symptoms in viral causes, eosinophilia and a tropical travel history can be related to parasitic etiology, and immunocompromising condition suggests fungal infection. Rhabdomyolysis, leukocytosis and elevated C-reactive protein ...
Source: Revue de Medecine Interne - March 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Seronegative antiphospholipid syndrome: Myth or reality?]
Authors: Salle V Abstract The antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombosis and/or obstetrical manifestations and the persistent presence, at least 12 weeks apart, of antiphospholipid antibodies (aPL) such as lupus anticoagulant (LA) and/or anticardiolipin antibodies (ACL) and/or anti-β2 glycoprotein I antibodies (aβ2GPI). The finding of patients with clinical profile highly suggestive of APS but who are negative for conventional biological criteria has led to the concept of seronegative APS. In the last few years, new antigen targets and methodological appro...
Source: Revue de Medecine Interne - March 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Scientific misconduct: A major threat for medical research].
Authors: Barde F, Peiffer-Smadja N, de La Blanchardière A Abstract Scientific misconduct (fabrication, falsification, and plagiarism) and detrimental research practices (selective reporting of data, inappropriate citation practice, ghostwriting) are admitted respectively by 2 % and 33 % of researchers. The consequences of scientific misconduct and detrimental research practices are disastrous, both for the doctors, who are the most affected researchers in view of the number of retracted articles, and for the patients, victims of false information that may have health consequences. In order to fight...
Source: Revue de Medecine Interne - March 1, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Thyroiditis: What's new in 2019?]
Authors: Rouland A, Buffier P, Petit JM, Vergès B, Bouillet B Abstract Thyroiditis is a frequent and mostly benign disease that can sometimes disrupt the thyroid balance. Their diagnosis, as well as their aetiology, is a necessary step in the management of the patients. Painful thyroiditis includes acute thyroiditis of infectious origin and subacute thyroiditis. The first one can be treated by antibiotics or antifungals depending on the germ found. The second one will be treated with non-steroidal anti-inflammatory drugs or corticosteroids. In cases of Hashimoto's thyroiditis with overt hypothyroidism, repla...
Source: Revue de Medecine Interne - March 1, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Wells syndrome misdiagnosed as bacterial cellulitis].
We report a case of WS presenting as bacterial cellulitis. A 59 year-old woman was referred to our department with a 10-day history of a rapidly extending erysipelatoid rash of the left upper limb, non-responding to oral antibiotics. Upon physical examination, erythema with swelling and blisters were found on the left upper limb with urticarial-like lesions on the breast, the belly and on the inner thighs. The patient was admitted with presumed bacterial cellulitis and was treated with intravenous ampicillin. Blood count showed raised eosinophils (2050/ul) along with a biological inflammatory syndrome. Biopsies were perfor...
Source: Revue de Medecine Interne - February 26, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Cholesterol crystal embolism mimicking a DRESS].
CONCLUSION: This case is the first to report a DRESS like presentation of CCE. Clinical findings are secondary to HE and not to occlusion of cutaneous arteries. PMID: 32089328 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 26, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Update on cholesterol crystal embolism].
Authors: Denis Le Seve J, Gourraud Vercel C, Connault J, Artifoni M Abstract Cholesterol crystal embolism is a systemic pathology associated with diffuse atherosclerosis. Pathophysiology corresponds to tissue necro-inflammation secondary to arteriolar occlusion associated with microembolism from atherosclerotic plaques of large diameter arteries. The clinical presentation is heterogeneous and polymorphic. Multiple organs may be the targets, but preferential damage is skin, kidneys and digestive system. It is a serious pathology, underdiagnosed, with a poor prognosis. The risk factors for developing the disease rema...
Source: Revue de Medecine Interne - February 24, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Comments on Gratzer et al.: ``Des guidelines pour l'intelligence artificielle !''].
Authors: Galland J PMID: 32088098 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 24, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Botulism: A case report and literature review].
CONCLUSION: Although botulism is uncommon, better awareness of its manifestations and high clinical suspicion should shorten diagnostic delay that makes the use of specific antitoxin ineffective. An acute onset of a bilateral oculomotor palsy, a fixed pupillary dilation and descending weakness in the absence of fever is typical of botulism. Outcome is usually favorable with a slow but full neurological recovery. PMID: 32061395 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 19, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Characteristics of Systemic Sclerosis patients with positive anti-Th/To antibodies: About 6 patients and literature review.
Authors: Muller R, Benyamine A, Bertin D, Harlé JR, Kaplanski G, Mazodier K, Reynaud-Gaubert M, Granel B, Bardin N Abstract Among the antibodies described in Systemic Sclerosis (SSc), anti-Th/To antibodies (anti-Th/To) are rare and have been poorly studied. Thus, little is known about the profile of anti-Th/To positive patients. From our local Biobank (Marseille, France), we retrospectively selected data for 6 patients positive for anti-Th/To with an Immunodot assay. All of them suffered from SSc, sharing clinical and biological common features such as a limited cutaneous form of SSc, a decreased lung diffus...
Source: Revue de Medecine Interne - February 19, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[From fibrogenesis towards fibrosis: Pathophysiological mechanisms and clinical presentations].
Authors: Maria ATJ, Bourgier C, Martinaud C, Borie R, Rozier P, Rivière S, Crestani B, Guilpain P Abstract Fibrogenesis is a universal and ubiquitous process associated with tissue healing. The impairment of tissue homeostasis resulting from the deregulation of numerous cellular actors, under the effect of specific cytokine and pro-oxidative environments can lead to extensive tissue fibrosis, organ dysfunction and significant morbidity and mortality. This situation is frequent in internal medicine, since fibrosis is associated with most organ insufficiencies (i.e. cardiac, renal, or hepatic chronic failures)...
Source: Revue de Medecine Interne - February 14, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[In patients with recent myocardial infarction, is colchicine effective in preventing cardiovascular events with a safety profile equivalent to placebo?]
Authors: Lanthier L, Dussault C, Huard G, Plourde MÉ, Cauchon M PMID: 32037255 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 11, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Thrombosis and platelet dysfunction in myeloproliferative neoplasms].
Authors: Mornet C, Galinat H, Mingant F, Ianotto JC, Lippert E Abstract Myeloproliferative neoplasms are acquired hematological malignancies, mainly affecting the adult and whose morbidity and mortality stems from haemostasis disorders. The most frequently encountered complications include thrombosis, affecting preferentially the arterial territory, but also atypical locations such as splanchnic vein thrombosis. The pathophysiology of these thromboses is complex and involves different actors: blood cells, endothelium and flow conditions. Numerous studies have been conducted to identify risk factors for thrombosis. ...
Source: Revue de Medecine Interne - February 6, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Assessment of a newly-implemented blended teaching of intensive care and emergency medicine at Paris-Diderot University].
Authors: Vodovar D, Ricard JD, Zafrani L, Weiss E, Desrentes E, Roux D Abstract INTRODUCTION: Blended-learning methods could be a response to student nonattendance. Non-compulsory teaching combining e-learning/interactive face-to-face sessions has been implemented at Paris-Diderot Medical School for the teaching of intensive care and emergency medicine during the 2018/2019 university period. The aim of the study was to assess this newly-implemented blended teaching. METHODS: Questionnaire submitted to the 388 DFASM3 medical students present at the faculty exam of intensive care/emergency medicine. Attendance at...
Source: Revue de Medecine Interne - February 6, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Tick-borne relapsing fever  : An unrecognized cause of fever in travellers].
CONCLUSION: This diagnosis should be evocated in patients having fever after a trip in infested area, as malaria, both infections can be associated. PMID: 32014353 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 6, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Restless legs syndrome].
Authors: Vellieux G, d'Ortho MP Abstract Restless legs syndrome, also called Willis-Ekbom disease, is a frequent sensorimotor disease, more often encountered in women than men. It is characterized by an urge to move legs, during the evening or the beginning of the night, increased by rest and relieved by movement. Two forms are classically distinguished: primary restless legs syndrome occurring in young adults with family history and secondary forms occurring in older adults with comorbidities such as iron deficiency, chronic renal failure or neurological diseases (affecting central or peripheral nervous system). T...
Source: Revue de Medecine Interne - February 4, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Do artificial intelligence systems reason in the same way as clinicians when making diagnoses?]
Authors: Pelaccia T, Forestier G, Wemmert C Abstract Clinical reasoning is at the heart of physicians' competence, as it allows them to make diagnoses. However, diagnostic errors are common, due to the existence of reasoning biases. Artificial intelligence is undergoing unprecedented development in this context. It is increasingly seen as a solution to improve the diagnostic performance of physicians, or even to perform this task for them, in a totally autonomous and more efficient way. In order to understand the challenges associated with the development of artificial intelligence, it is important to understand ho...
Source: Revue de Medecine Interne - January 30, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Facial edema and erythroderma in a 54 year-old woman].
Authors: Mourguet M, Lajaunie R, Schouler M, Godart M, Bonnet D, Riffaud L, Lamant L, Alric L, Rossi B PMID: 31987672 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 30, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Acute autoimmune myocarditis secondary to Graves' disease: a case report].
CONCLUSION: Acute myocarditis is an exceptional complication of Graves' disease, with most likely an autoimmune mechanism. Possible occurrence of fulminant rhythmic or hemodynamic complications justify minimal cardiological check-up before introducing beta blockers. PMID: 31982255 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 28, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Association between psychiatric comorbidities and hospital length of stay in post-emergency internal medicine patients].
Authors: Lampros A, Montardi C, Journeau L, Georgin-Lavialle S, Hanslik T, Dhôte R, Goujard C, Le Jeunne C, Mahe I, Papo T, Godeau B, Bourgarit A, Fain O, Fantin B, Dzierzynski N, Leblanc J, Nevoret C, Steichen O Abstract INTRODUCTION: Patients with psychiatric disorders suffer from a higher rate of somatic disorders than those without psychiatric disorder, often inappropriately managed. Our study aimed to describe patients with psychiatric comorbidity in post-emergency internal medicine units and to compare their length of hospital stay to patients without psychiatric disease. METHODS: This French cross ...
Source: Revue de Medecine Interne - January 28, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Purtscher-like retinopathy associated with adult onset still disease: Case report and review of the literature].
CONCLUSION: When visual functional signs appear during adult Still's disease, it is necessary to evoke Putscher-like retinopathy, and to ask for an ophthalmological expertise. PMID: 31983549 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 28, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Third degree atrio-ventricular blockade during a myocarditis occurring under anti-PD1  : Case report and literature review].
CONCLUSION: Myocarditis occurring during ICI treatment is a rare but potentially lethal event. Daily serum troponin level seems to predict ICI-related myocarditis but interpretation could be difficult in the context of associated myositis. Echocardiography and cardiac MRI are also useful but can remain negative. Electrocardiogram is a cornerstone of myocarditis diagnosis. In case of cardiac involvement, continuous heart rhythm monitoring should be performed in addition to the administration of high-dose corticosteroids therapy and the cessation of ICI therapy. Add-on treatments should be discussed with a well-trained multi...
Source: Revue de Medecine Interne - January 28, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A new case of rare erythrocytosis due to EGLN1 mutation with review of the literature].
CONCLUSION: In the face of an unexplained polycythemia a good cooperation between clinicians and biologists is necessary to be able to characterize rare hereditary pathologies. PMID: 31980185 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 27, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Carpal tunnel syndrome: Rare causes and associated forms behind a common and stereotyped affection].
Authors: Fournier E Abstract Carpal tunnel syndrome (CTS) is too common a condition not to daily interact with the practitioner, if only because of its entanglement to other pathologies, causal or chance association. The typical symptomatology, with hand paresthesia and morning pain upon waking, is related to a median nerve injury in the confined space of the carpal tunnel, more often by local inflammation and tenosynovitis of the finger flexors (repetitive activity of the hands). SCC may be secondary to situations (pregnancy) or conditions (edema, hypothyroidism…), which exaggerate the ordinary pathophysiol...
Source: Revue de Medecine Interne - January 27, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Enteroviral infections in adults treated with rituximab: A new case of chronic meningitis and myofasciitis and literature review].
CONCLUSION: We report a case of chronic enterovirus infection associating meningitis and myofasciitis in an adult with rituximab-induced hypogammaglobulinemia. Outcome was favorable under treatment with intravenous immunoglobulins. PMID: 31980187 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 27, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Resistant and progressive cutaneous lupus erythematosus treated with belimumab: A retrospective monocentric study].
CONCLUSION: Our study suggests the clinical efficiency of belimumab in a series of 7 patients presenting a resistant and progressive CLE. PMID: 31980188 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 27, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Mucopolysaccharidosis: A review].
Authors: Michaud M, Belmatoug N, Catros F, Ancellin S, Touati G, Levade T, Gaches F Abstract Mucopolysaccharidosis are lysosomal storage diseases, secondary to the accumulation of mucopolysaccharides. Type 1 mucopolysaccharidosis is the most common form and affects between 0.69 and 1.66 newborns per 100,000. The severity of mucopolysaccharidosis is variable with lethal forms in utero and attenuated forms diagnosed in adults. The most common symptoms are short stature, facial dysmorphism, chronic articular pains that can mimic chronic inflammatory rheumatism, axial and peripheral bone involvement, hepatosplenomegaly...
Source: Revue de Medecine Interne - January 23, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Chez les sujets avec insuffisance cardiaque à fraction d’éjection diminuée avec ou sans diabète de type 2, est-ce que la dapagliflozine, un inhibiteur des SGLT2, est efficace pour prévenir l’insuffisance cardiaque décompensée ou la mortalité cardiovasculaire tout en étant sécuritaire ?
Chez les sujets avec insuffisance cardiaque à fraction d’éjection diminuée avec ou sans diabète de type 2, est-ce que la dapagliflozine, un inhibiteur des SGLT2, est efficace pour prévenir l’insuffisance cardiaque décompensée ou la mortalité cardiovasculaire tout en étant sécuritaire ? Rev Med Interne. 2020 Jan 09;: Authors: Lanthier L, Dussault C, Huard G, Plourde MÉ, Cauchon M PMID: 31928796 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 15, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

The prevalence, determinants and the role of empathy and religious or spiritual beliefs on job stress, job satisfaction, coping, burnout, and mental health in medical and surgical faculty of a teaching hospital: A cross-sectional survey.
Authors: Lal A, Tharyan A, Tharyan P Abstract OBJECTIVE: Systematically ascertained data on job stress and burnout and their antecedents and mediators in health professionals from low- and middle-income countries are scant. METHODS: This cross sectional survey, conducted from July 2007 to August 2008, of consenting medical and surgical faculty of a large, charitable, teaching hospital aimed to evaluate: 1) the prevalence and sources of job stress and job satisfaction, and the ways used to cope with stress; 2) the prevalence of burnout and mental distress; and 3) the influence of age, gender, empathy and religio...
Source: Revue de Medecine Interne - January 13, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research