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[A blue finger].
Authors: Blaison F, Lifermann F, Baudry V PMID: 29310967 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 11, 2018 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Abdominal pain of vascular cause].
Authors: Nuzzo A, Ronot M, Maggiori L, Joly F, Corcos O PMID: 29307604 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 10, 2018 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Prospective study of the factors associated with the acceptance of generics substitution by patients and their liberal doctors].
Authors: Iskounen S, Simoneau G, Mouly S Abstract BACKGROUND: Many prescribers and patients remain reluctant to substitution to generics. METHODS: We conducted a prospective observational study, using semi-structured interviews adapted to identify factors independently associated with the acceptance of alternative to a generic drug by doctors and patients. RESULTS: Between December 2014 and August 2015, 108 patients and 73 private doctors from Île-de-France and Nord-Pas-de-Calais were enrolled. Only 48 % of patients thought that the effectiveness and safety of generic were identica...
Source: Revue de Medecine Interne - January 3, 2018 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A POEMS syndrome revealed by a blue toe syndrome].
CONCLUSION: This is to our knowledge the first case of thrombotic microangiopathy in POEMS syndrome without embolic cause or calciphylaxis. PMID: 29288001 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 1, 2018 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Blood management in geriatric hospitalized population].
The objective of our study was to show the impact of a decision support tool on transfusion practices, specifically in a hospitalized elderly population. METHOD: A clinical decision support, validated in the improvement of practices, was created, based on the latest transfusion recommendations of 2014. Our study was interventional, monocentric, within the departments of internal medicine and geriatrics of a university hospital from February to July 2016. The clinical decision support was available for any request of transfusion of packed red blood cells for 75 years old or older patient who was hospitalized in one of t...
Source: Revue de Medecine Interne - December 31, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Sarcoidosis post-anti-PD-1 therapy, mimicking relapse of metastatic melanoma in a patient undergoing complete remission.
We report a patient developing pulmonary and cutaneous sarcoidosis after pembrolizumab therapy while complete regression of stage IV melanoma was perceived. Coincident development of sarcoidosis and metastatic melanoma as illustrated by this case report poses a diagnostic challenge because, in contrast to other irAEs, both diseases share common features such as pulmonary lesions, hilar adenopathies and skin nodules. Considering sarcoidosis as a potential side-effect of pembrolizumab treatment is crucial to avoid misdiagnosis with malignant lesions, hence careful description and reporting of such cases is primordial for pat...
Source: Revue de Medecine Interne - December 28, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Multiple facets of ADA2 deficiency: Vasculitis, auto-inflammatory disease and immunodeficiency: A literature review of 135 cases from literature].
Authors: Fayand A, Sarrabay G, Belot A, Hentgen V, Kone-Paut I, Grateau G, Melki I, Georgin-Lavialle S Abstract Deficiency of adenosine deaminase 2 (DADA2) is a recently described auto-inflammatory disorder. It is an autosomal recessive inherited disease, caused by mutations in the ADA2 gene (formerly known as CECR1) encoding ADA2 enzyme. Besides its role in the purine metabolism, it has been postulated that ADA2 may act as a growth factor for endothelial cells and in the differenciation of monocytes. Thus, deficiency of ADA2 would lead to endothelial damage and a skewing of monocytes into M1 pro-inflammatory macro...
Source: Revue de Medecine Interne - December 25, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Splenic sarcoidosis diagnosed by US-guided biopsy: About a case].
CONCLUSION: Diagnosis of splenic nodular sarcoidosis can be challenging without any other localization. Splenic biopsy achieved diagnosis. This procedure is associated with a low risk of complications - in particular hemorragic ones. Diagnostic splenectomy should be an exceptional intervention. PMID: 29274795 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - December 25, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Compliance with treatment in Wilson's disease: On the interest of a multidisciplinary closer follow-up].
CONCLUSION: Wilsons's disease patients have important problems with compliance, without necessary being depressed. A close follow-up may help them become compliant, particularly those with neurological symptoms. PMID: 29274796 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - December 25, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Lemierre's syndrome: Diagnosis, exploration, treatment].
Authors: Mesrar H, Mesrar J, Maillier B, Kraoua S, Chapoutot L, Delclaux B Abstract Lemierre's syndrome is a rare and severe sepsis that can rapidly lead to a life-threatening condition in the absence of early management. This syndrome described at the beginning of the 20th century combines oropharyngeal infection complicated with septic thrombosis of the internal jugular vein and septic emboli predominantly pulmonary. Fusobacterium necrophorum, anaerobic germ, Gram negative bacillus is the main germ in this "necrobacillosis". The diagnosis is should be confirmed precociously with cervicothoracic CT-scan,...
Source: Revue de Medecine Interne - December 24, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A predictive bacterial infection score according to eosinophil level: An observational study].
CONCLUSION: The CIBLE score appears to be a relevant and inexpensive tool to establish a probability for bacterial infection. PMID: 29223347 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - December 12, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Efficacy and tolerance of tocilizumab for corticosteroid sparing in giant cell arteritis and aortitis: Experience of Nimes University Hospital about eleven patients].
CONCLUSION: Tocilizumab could be efficient and well-tolerated in steroid-dependent giant cell arteritis and aortitis. The modalities of its use remain to be precised. PMID: 29221884 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - December 11, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Does tocilizumab mean the end of glucocorticoids in giant cell arteritis?]
Authors: Samson M, Bonnotte B PMID: 29217104 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - December 9, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Sedimentary cutaneous lesions].
Authors: Oehler E, Fialek M PMID: 29195771 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - December 5, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Heart failure of unusual cause].
Authors: Nèji H, Baccouche I, Attia M, Affes M, Kammoun I, Hantous-Zannad S, Ben Miled-M'rad K PMID: 29153345 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - November 22, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Validit é et reproductibilité de deux grilles d’observation des compétences cliniques des internes en DES de médecine interne.
CONCLUSION: If the absolute value of the scores should not be taken into account in the evaluation process given its high variability, it could be of interest for the follow-up of the progression in the competencies. These forms could support the residents' debriefing based on the general trends given by the scores. PMID: 29157753 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - November 22, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Should statin therapy be discontinued in the elderly?]
Authors: Bonnet F PMID: 29157754 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - November 22, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Acetaminophen induced 5-oxoproline acidosis: An uncommon case of high anion gap metabolic acidosis].
We describe a case of 5-oxoproline (pyroglutamate) acidosis due to chronic acetaminophen ingestion at therapeutic dose in a 79-year-old inpatient. The pathophysiology of this condition is detailed, with abnormalities in the gamma-glutamyl cycle due to acetaminophen ingestion and severe chronic morbidities, resulting in glutathione and cysteine deficiency and then accumulation of 5-oxoproline. In HAGMA, when usual causes have been excluded, 5-oxoproline acidosis should be suspected in patients with chronic morbidities and acetaminophen ingestion. This diagnosis should be kept in mind because it generally resolves quickly wi...
Source: Revue de Medecine Interne - November 22, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Chronic histiocytic intervillositis: Diagnosis and management].
Authors: Mekinian A, Costedoat-Chalumeau N, Carbillon L, Coulomb-L'Hermine A, Le Guern V, Masseau A, Lazaro E, Cohen J, Bornes M, Kayem G, Fain O Abstract Chronic intervillositis is a rare condition, which is associated with severe obstetrical outcome and high recurrence rate. Obstetrical adverse events are intrauterine growth restriction, recurrent early miscarriages, intrauterine deaths and prematurity by placental insufficiency. The determination of the extension and the intensity of the chronic intervillositis are not currently standardized. High rates of recurrence have been described, but actually there is no...
Source: Revue de Medecine Interne - November 18, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Confusion and weight loss].
Authors: Cacciatore C, Mekinian A, Arrivé L, Adedjouma A, Fain O PMID: 29146014 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - November 18, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Aspirin: Indications and use during pregnancy].
Authors: Belhomme N, Doudnikoff C, Polard E, Henriot B, Isly H, Jego P Abstract Aspirin (acetylsalicylic acid) has been used ever since the Antiquity for its painkilling and anti-inflammatory effects. Its antiplatelet properties have then extended its indications to the field of coronaropathy and vascular cerebral disease, and finally to vascular placental disease. Aspirin has been widely prescribed since the 1980's to prevent pre-eclampsia, intra-uterine growth retardation and fetal death of vascular origin. It has also been proposed to prevent unexplained recurrent miscarriages. Its use during pregnancy is consid...
Source: Revue de Medecine Interne - November 15, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Diagnostic issues of lymphogranuloma venereum: A case series of 5  patients].
CONCLUSION: LG should be evoked in any patient with inguinal adenomegaly, particularly in case of STI history or risk factors. Negativity of urinary PCR should lead to further investigations, essentially a lymph node cytopuncture to evidence C. trachomatis. PMID: 29128125 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - November 14, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Uveitis: Diagnostic work-up. Recommendations from an expert committee].
CONCLUSIONS: We propose a strategy for the etiologic diagnosis of uveitis. The recommendations should be updated regularly. The efficiency of more invasive investigations has yet to be evaluated. PMID: 29122311 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - November 12, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Cryopyrin-associated periodic syndromes].
Authors: Quartier P, Rodrigues F, Georgin-Lavialle S Abstract Cryopyrin-associated periodic syndromes (CAPS) are linked to one single gene mutations, however they are associated with 3 syndromes, which are, from the mildest to the most severe phenotype familial cold urticaria, Muckle-Wells syndrome and chronic, infantile, neurologic, cutaneous, articular (CINCA) syndrome also called neonatal-onset multisystem inflammatory disease (NOMID). Autosomic dominant inheritance is present in most cases but in CINCA/NOMID syndrome where neomutations are more common. Mutations in the gene encoding cryopyrin, NLRP3, are associ...
Source: Revue de Medecine Interne - November 8, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[End-of-life debate: Citizen's point of view about deep and continuous sedation].
CONCLUSION: Deep and continuous sedation is perceived as a euthanasic practice or raises fear of such a drift. Provision of extended and accurate information to the population and health professionals is essential to ensure that this new model of sedation is integrated into the care of the terminally ill patients and their families. PMID: 29102388 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - November 7, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Abnormal hair].
Authors: Coen M, Cramer B, Serratrice J PMID: 29054584 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - October 23, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Influence of epigenetic in Sj ögren's syndrome].
[Influence of epigenetic in Sjögren's syndrome]. Rev Med Interne. 2017 Oct 17;: Authors: Bordron A, Charras A, Le Dantec C, Renaudineau Y Abstract Sjögren's syndrome (SS) is a systemic autoimmune epithelitis with a major female incidence, and characterized by a dry syndrome, impaired quality of life, visceral involvement, and lymphoma for the most aggressive cases. During this process, epithelial cells acquire the capacity to produce cytokines, chemokines, and autoantigens which can in turn be presented to the immune system. Consequently, this epithelitis is accompanied by lymphocytic infiltr...
Source: Revue de Medecine Interne - October 23, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Movement disorders: An update].
Authors: Béreau M, Tranchant C Abstract Movement disorders (tremor, chorea, dystonia, tics, and myoclonus) are related to basal ganglia and/or interconnected brain areas dysfunction. Clinical examination is a key point in order to characterize the abnormal movement and identify associated signs that can guide etiological approach. Iatrogenic diseases will be systematically ruled out before conducting additional investigations (brain MRI, electrophysiological studies). Wilson disease, but also other treatable metabolic and/or genetic diseases, and auto-immune diseases will be systematically considered. Therap...
Source: Revue de Medecine Interne - October 22, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Ocular sarcoidosis: What the internist should know?]
Authors: Sève P, Kodjikian L, Jamilloux Y Abstract Sarcoidosis is one of the leading causes of inflammatory eye disease. Any part of the eye and its adnexal tissues can be involved. Uveitis and optic neuropathy are the main manifestations, which the internists face. This review reports the state of knowledge for these two ocular involvements and proposes an assessment-algorithm for sarcoidosis in patients with suspected sarcoid uveitis. Two groups of patients with sarcoid uveitis can be distinguished: one young and multiethnic group in which ophthalmological findings are various and another group of elderly ...
Source: Revue de Medecine Interne - October 19, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Severity of illness index in autoimmune diseases: Have there any usefulness in medical practice?]
CONCLUSION: The discrepancy between the ratio of practitioners who believe that scores have a place in daily practice and their actual use shows that the current scores do not meet the needs. The implementation of easily usable activity scores in inflammatory diseases remains a challenge for the internists. PMID: 29032100 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - October 18, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Lymphomas: A therapeutic update].
The objective of this review is to trace history of the latest advances, and to highlight the validated strategies representing the new standards of treatment of lymphomas in 2017. PMID: 28958786 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - October 1, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Focal myositis: An unknown disease].
Authors: Gallay L, Streichenberger N, Benveniste O, Allenbach Y Abstract Focal myositis are inflammatory muscle diseases of unknown origin. At the opposite from the other idiopathic inflammatory myopathies, they are restricted to a single muscle or to a muscle group. They are not associated with extramuscular manifestations, and they have a good prognosis without any treatment. They are characterized by a localized swelling affecting mostly lower limbs. The pseudo-tumor can be painful, but is not associated with a muscle weakness. Creatine kinase level is normal. Muscle MRI shows an inflammation restricted to a mus...
Source: Revue de Medecine Interne - September 29, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Hemolytic and uremic syndrome and related thrombotic microangiopathies: Treatment and prognosis].
Authors: Rafat C, Coppo P, Fakhouri F, Frémeaux-Bacchi V, Loirat C, Zuber J, Rondeau E Abstract Major achievements in the understanding of thrombotic microangiopathies (TMA) have not only resulted in a reclassification of TMA but most of all they have culminated in the design of new treatments and have enabled clinicians to better delineate their prognosis. Recent multicenter studies have improved our understanding of the prognosis of atypical hemolytic and uremic syndromes (aHUS). More specifically, they have highlighted the role of genetic testing on predicting the recurrence of aHUS, the risk of chronic k...
Source: Revue de Medecine Interne - September 29, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Hands and feet lesions].
Authors: Suzon B, Arnaud E, Galy C, Broner J PMID: 28942058 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - September 26, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Screening and clinical implications of silent atrial fibrillation].
Authors: Guenancia C, Garnier F, Mouhat B, Béjot Y, Maillot N, Fichot M, Fauchier L, Cottin Y Abstract Each year, 5 million new cases of atrial fibrillation (AF) are diagnosed, and the data for the last 20 years show that its incidence has continued to grow. The aging of the population is considered a major explanation for this pandemic phenomenon. The complications associated with atrial arrhythmia are numerous and frequent, with in the first place thromboembolic events. In addition to symptomatic atrial fibrillation, AF may be diagnosed by chance during a systematic ECG, an external Holter or a continuous ...
Source: Revue de Medecine Interne - September 26, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Cutaneous lesions].
Authors: Mohamed M, Korbi M, Hadhri R, Belhadjali H, Zili J PMID: 28942938 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - September 26, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Relapsing polychondritis: What's new in 2017?]
Authors: Dion J, Leroux G, Mouthon L, Piette JC, Costedoat-Chalumeau N Abstract Relapsing polychondritis (RP) is a rare condition characterized by recurrent inflammation of cartilaginous tissue and systemic manifestations. Data on pathophysiology are scarce and suggest an autoimmune mechanism. Recently, the possibility of dividing patients with RP into three distinct clinical phenotypes has been suggested: the hematological form representing less than 10% of patients, essentially older men with associated myelodysplasia and poor prognosis, the respiratory form representing about 25% of patients with predominant tra...
Source: Revue de Medecine Interne - September 12, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Secondary thrombotic microangiopathies].
Authors: Coppo P, Centre de référence des microangiopathies thrombotiques (CNR-MAT) Abstract Thrombotic microangiopathies (TMA) are termed secondary when associated to a specific context favouring their occurrence. They encompass mainly TMA associated with pregnancy, allogeneic hematopoietic stem cell transplantation, cancer, drugs, or HIV infection. Secondary TMA represent a heterogeneous group of diseases which clinical presentation largely depends on the associated context. It is therefore mandatory to recognize these conditions since they have a significant impact in TMA management and prognosis. ...
Source: Revue de Medecine Interne - September 12, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Weight loss and fever].
Authors: Hocqueloux M, Enfrein A, Génin V, Caristan A, Néel A, Agard C PMID: 28882622 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - September 9, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Acute management of ischemic stroke in 2017].
Authors: Blanc-Labarre C, Delpont B, Hervieu-Bègue M, Osseby GV, Ricolfi F, Thouant P, Giroud M, Béjot Y Abstract Acute management of ischemic stroke is a burning topic in 2017 since stroke represents the leading cause of acquired handicap in adults. Over the last past years, major improvement took place, especially with the demonstration of the efficacy of mechanical thrombectomy, thus needing to better organize care pathways, and optimize access to neurologists and interventional neuroradiology platforms. Intensive care stroke units remain the pivotal place of patients' management. A multidisciplina...
Source: Revue de Medecine Interne - September 6, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Eosinophilia heralding the diagnosis of eosinophilic fasciitis (Shulman's disease)].
CONCLUSION: In this case report, eosinophilia was preceding the clinical cutaneous signs that led to the diagnosis of eosinophilic fasciitis. It is likely to believe that myalgias, frequently found in the onset of eosinophilic fasciitis, may have been hidden by the history of infantile encephalopathy. The diagnosis of eosinophilic fasciitis must be kept in mind of physicians in the investigation of an eosinophilia, even though cutaneous signs are lacking. PMID: 28867532 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - September 6, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Primary intestinal lymphangiectasia (Waldmann's disease)].
Authors: Vignes S, Bellanger J Abstract Primary intestinal lymphangiectasia (PIL), Waldmann's disease, is a rare disorder of unknown etiology characterized by dilated intestinal lacteals leading to lymph leakage into the small-bowel lumen and responsible for protein-losing enteropathy leading to lymphopenia, hypoalbuminemia and hypogammaglobulinemia. PIL is generally diagnosed before 3 years of age but may be diagnosed in older patients. The main symptom is bilateral lower limb edema. Edema may be moderate to severe including pleural effusion, pericarditis or ascites. Protein-losing enteropathy is confirmed by...
Source: Revue de Medecine Interne - September 6, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Vitamin K antagonist-induced necrotic leg ulcer, without protein C and S deficiencies].
CONCLUSION: We report an original case of necrotic leg ulcers induced by VKA without deficit of protein C or S, with a pyoderma like histology. Reported cases of ulcers induced by VKA are uncommon and the physiopathology is not well known. The involvement of VKA should be evoked in case of necrotic leg ulcer without specific etiology found. PMID: 28867534 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - September 6, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Statins in primary prevention of cardiovascular disease].
We report in this review the updated conclusions from clinical trials regarding the treatment with statins in primary prevention. PMID: 28866432 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - September 5, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A case of gonococcal arthritis: Diagnostic difficulties and usefulness of synovial fluid PCR].
CONCLUSION: In patients with high risk of N. gonorrhoeae infection, PCR for detection of gonorrhea in synovial fluid could potentially facilitate the diagnostic of gonococcal septic arthritis. PMID: 28844395 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - August 30, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Extensive cutaneous lesions].
Authors: Fenot M, Riegert M, Poiraud C, Gegu M, André V PMID: 28844396 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - August 30, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Vascular renal abnormalities].
Authors: Journeau L, Vincent M, Perret C, Connault J PMID: 28838606 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - August 27, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[From pathogenesis of giant cell arteritis to new therapeutic targets].
Authors: Samson M, Bonnotte B Abstract Giant cell arteritis (GCA) is the most common vasculitis in adults. GCA is a granulomatous large-vessel vasculitis involving the aorta and its major branches in people>50 years. Glucocorticoids (GC) remain the cornerstone of GCA treatment. Prednisone is usually started at 0.7 or 1mg/kg/day depending on the occurrence of ischemic complications. Then, GC are progressively tapered and stopped after a mean duration of 18 months. GC are very efficient but relapses often occur during their tapering. Moreover, GC-related side effects are very common during this long term...
Source: Revue de Medecine Interne - August 13, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Vasculitis of the hepatic artery: A case of a single-organ vasculitis].
We report the case of a patient who developed a vasculitis of the right and left hepatic arteries. CASE REPORT: A 63-year-old woman presented with unexplained abdominal pain. A computed tomography of the abdomen was suggestive of vasculitis of the hepatic arteries, showing a sequence of stenosis and aneurysmal dilatations of the hepatic arteries. There were no other arterial involvement, in particular of the abdomen and the brain. No other systemic disease or infection was found. The outcome was favorable, with corticosteroids alone. DISCUSSION: The exclusive involvement of the hepatic artery is an exceptional form...
Source: Revue de Medecine Interne - August 10, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Weakness of the left hand and pallor in a 21-year-old woman].
Authors: de Luna G, Arlet JB, Passeron A, Ranque B, Michon A, Pouchot J, Lozac'h P, Lapoirie J, Bourdin V PMID: 28780283 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - August 7, 2017 Category: Internal Medicine Tags: Rev Med Interne Source Type: research