[A pleural effusion of unusual cause].
Authors: Gilard V, Clavier T, Proust F, Fréger P, Derrey S PMID: 26948270 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - March 9, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Differential diagnosis of aortitis].
Authors: Rousselin C, Pontana F, Puech P, Lambert M Abstract Aortitis are mainly described in inflammatory disorders such as Takayasu arteritis, giant cell arteritis or Behçet's disease. Aortitis is sometimes qualified as idiopathic. However, differential diagnoses must be searched since they need specific interventions. Infectious aortitis should be ruled out first as its rapid evolution and short-term poor prognosis makes it a therapeutic emergency. Furthermore, rarer differential diagnoses should be known as they require specific care that might sometimes differ from the treatment of inflammatory aortitis...
Source: Revue de Medecine Interne - March 9, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Kikuchi-Fujimoto's disease or histiocytic necrotizing lymphadenitis: A report of two familial cases].
CONCLUSION: Pathophysiology of Kikuchi-Fujimoto's disease is probably multifactorial and may include predisposing genetic background and a possible infectious triggering event. PMID: 26907374 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 27, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Prevention of infections in adults and adolescents with systemic lupus erythematosus: Guidelines for the clinical practice based on the literature and expert opinion].
CONCLUSION: These recommendations can be expected to improve clinical practice uniformity and, in the longer term, to optimize the management of SLE patients. PMID: 26899776 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 24, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Death certificate data in France: Production process and main types of analyses].
This article describes the data production process, and the main types of possible analyses. Data production is composed of different stages: death certification by a medical doctor on paper or electronic (using a web application) format, data transmission to Inserm, capture and coding of information. The encoding of the information follows the WHO recommendations of the International Classification of Diseases ([ICD], 10th revision used since 2000). It is carried out using an automatic coding software, called Iris, developed in an international consortium. The coding aims, first, at assigning an ICD code to all nosologic ...
Source: Revue de Medecine Interne - February 23, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Lung sarcoidosis: Clinical features and therapeutic issues].
Authors: Uzunhan Y, Jeny F, Crockett F, Piver D, Kambouchner M, Valeyre D, Nunes H Abstract Sarcoidosis is a granulomatous disease of unknown cause. This proteiform disease is characterized by an almost constant and often predominant lung involvement. The natural history of disease is difficult to predict at presentation. Diagnosis is based on a compatible clinical and radiological presentation and evidence of non-caseating granulomas. Exclusion of alternative diseases is also required according to clinical presentation. Biopsy samples of superficial lesions should be considered before other sites like per-endoscop...
Source: Revue de Medecine Interne - February 23, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Digestive neuroendocrine tumors].
Authors: de Mestier L, Deguelte-Lardière S, Brixi H, Kianmanesh R, Cadiot G Abstract Digestive neuroendocrine tumors (NETs) are a group of rare tumors with increasing incidence. Pathological analysis is critical to establish the diagnosis and evaluate tumor grade that relies on differentiation and proliferation index. NETs are mostly diagnosed at an advanced stage because of late occurrence of nonspecific symptoms, and can be associated with hormone hypersecretion. Chromogranin A is the main biochemical marker of NETs. Extension workup relies on conventional imaging (CT-scan, MRI) and isotopic imaging i...
Source: Revue de Medecine Interne - February 23, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Usefulness of imaging in large vessel vasculitis].
Authors: Mekinian A, Djelbani S, Viry F, Fain O, Soussan M Abstract The imaging is essential for the diagnosis of large vessels arteritis, in order to assess the persistent inflammation of arterial lesions, to evaluate the treatment response and search the vascular complications. In patients with giant cell arteritis (GCA), the aortitis could be suspected in 2 situations: in the presence of general constitutional symptoms or systematic screening of aortitis in patient with confirmed GCA. The frequency of aortitis varies according to the imaging method and could be detected in 40 % of patients with compute...
Source: Revue de Medecine Interne - February 18, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Amyloidosis: Up-to-date].
Authors: Magy-Bertrand N Abstract Amyloidosis is mainly a systemic disease belonging to protein-folding diseases. The past 10 years have shown significant progress in typing and the clinical management of amyloidosis, in the identification of novel prognostic markers for risk-stratification, and also in the development of new therapeutic agents. Biological molecular techniques are now able to type amyloidosis which were unidentified. Cardiac MRI and biomarkers allow a precise risk-stratification, especially in AL amyloidosis. If necessary, this prognostic evaluation may lead to rapid changes in the chemotherap...
Source: Revue de Medecine Interne - February 17, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Irritable bowel syndrome: New pathophysiological hypotheses and practical issues].
Authors: Duboc H, Dior M, Coffin B Abstract In 2015, besides the fact that it still fills the gastroenterologists' offices and impairs patient's quality of life, the irritable bowel syndrome has considerably evolved on several points. The pathophysiology is now organized around a consensual hypothesis called the "brain-gut axis", which gather all the influences of peripheral factors as gut microbiota or local serotonin secretion, on the central pain perception, contributing to visceral hypersensitivity and transit modifications. About the diagnosis, the key message is "avoid over-prescription" o...
Source: Revue de Medecine Interne - February 15, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Cardiac arrhythmias: Diagnosis and management].
Authors: Waldmann V, Marijon E Abstract Cardiac arrhythmias, with, on top of the list, atrial fibrillation, are frequent conditions and any physician might have to get involved at any stage of patient care (from diagnosis to treatment), without always having the opportunity to immediately refer to the cardiologist. The aim of this review is to present a summary of pathophysiology, clinical and electrocardiographic presentations, as well as diagnostic and therapeutic strategies for the main cardiac arrhythmias. Supra-ventricular tachycardias (atrial fibrillation and flutter, atrioventricular reciprocating tachycardi...
Source: Revue de Medecine Interne - February 15, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Efficiency and good tolerance of rituximab for idiopathic thrombocytopenic purpura revealing a 22q11 deletion syndrome].
CONCLUSION: Rituximab may be an alternative to corticosteroid for the treatment of auto-immune manifestations associated with minor forms of 22q11 deletion syndrome without significant worsening of the immune deficiency. PMID: 26869291 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 14, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Parkinsonian syndrome].
Authors: El Aoud S, Charfi N, Hajkacem F, Cheikhrouhou N, Mnif F, Abid M PMID: 26869292 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 14, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Therapeutic endovascular procedures in aortitis].
Authors: Del Giudice C, Alsac JM, Sapoval M Abstract Aortitis is an inflammation of the aortic wall with an infectious or non-infectious origin, which often progresses to vascular complications. The open surgical approach is a high-risk procedure for these pathologies. Endovascular interventions have improved the prognosis of patients with aortitis complications. This manuscript describes the pathophysiology responsible for vascular complications and the role of endovascular approach for their treatment. PMID: 26869293 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 14, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Cutaneous lesion].
Authors: Aaron L, Duchesne E PMID: 26869294 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 14, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Three cases of Jaccoud's arthropathy during systemic sclerosis].
CONCLUSION: We described 3 cases of Jaccoud's arthropathy among our scleroderma cohort of 296 patients (1%). This arthropathy worsens hand functional disability. Its pathophysiology is unknown and optimal therapeutic approach remains to establish. PMID: 26869295 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 14, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Bi-thalamic abnormality].
Authors: Puy L, Lamy C, Arnoux A, Zerbib Y, Constans JM, Godefroy O PMID: 26857331 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 11, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Experimentation of an e-platform to detect situations at risk of cardiac impairment (platform E-care) in an internal medicine unit].
CONCLUSION: Preliminary results following the deployment of E-care platform in hospitals appear to show the relevance of technological choices, tools and solutions developed and adopted. This telemedicine system allows automatic, non-intrusive, generate alerts related to the detection of situations at risk for heart failure. Ultimately, E-care was capable of preventing hospitalization. A home deployment is currently underway. PMID: 26852082 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 9, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A digital ischemia of unusual cause].
Authors: Thoreau B, Bigot A, Diallo BD, Pucheux J, Marchand E, Diot E PMID: 26852083 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 9, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Food-cobalamin malabsorption and vitamin B12 deficiency in adults and in elderly patients: What is the problem?]
[Food-cobalamin malabsorption and vitamin B12 deficiency in adults and in elderly patients: What is the problem?] Rev Med Interne. 2016 Feb 4; Authors: Andrès E, Vogel T, Kaltenbach G, Lang PO PMID: 26854093 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 9, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A very abnormal PET-CT].
Authors: Breton M, Thevenet H, Dallongeville A, Pouchot J, Jacquot C, Cornou C, Weinmann P PMID: 26833000 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 3, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Clinical efficacy of eculizumab as treatment of gemcitabine-induced thrombotic microangiopathy: A case report].
CONCLUSION: Eculizumab seems to be an effective treatment against gemcitabine-induced thrombotic microangiopathy in case of severe hematological and renal injuries associated with a lack of response to plasma exchange therapy. PMID: 26833144 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 3, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Management of giant cell arteritis: Recommendations of the French Study Group for Large Vessel Vasculitis (GEFA).
CONCLUSIONS: The recommendations, which will be updated regularly, are intended to guide and harmonize the standards of GCA management. PMID: 26833145 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 3, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Multiple myeloma and venous thrombosis. Which thromboprophylaxis should be given?]
Authors: de Moreuil C, Ianotto JC, Eveillard JR, Carrier M, Delluc A Abstract Multiple myeloma is a malignant plasma cells dyscrasia that mainly affects patients older than 65 years. These patients are at a higher risk for venous thromboembolism (VTE) because of cancer status, intrinsic risk factors, and exposure to prothrombotic therapies. The risk for VTE appears higher during the first months of myeloma treatment and decreases over time. Exposure to immunomodulatory drugs (IMIDs) such as thalidomide or lenalidomide in association with high doses of dexamethasone or anthracyclin-based chemotherapy is associa...
Source: Revue de Medecine Interne - February 3, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Physical activity and cancer: Update and literature review].
Authors: Desnoyers A, Riesco E, Fülöp T, Pavic M Abstract Physical activity is a key determinant of public health and contributes to decreasing the prevalence of many diseases. Cancer is the leading cause of death worldwide. Physical activity, accessible to the entire population, could prevent up to 25% of cancers, in addition to improving survival rates and quality of life in cancer patients. Physical activity acts via various mechanisms to slow or decrease tumor growth, including the production and bioavailability of sex hormones, insulin resistance and insulin secretion, and inflammation. In primary pr...
Source: Revue de Medecine Interne - February 2, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Aortitis].
Authors: Saadoun D, Messas E, Pouchot J, Mekinian A, Lambert M, Cacoub P, Mirault T PMID: 26827271 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 2, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Computerized ranking test in three French universities: Staff experience and students' feedback].
CONCLUSION: The organization of a mock ECNi involving multiple universities was a docimological and technical success but required an important administrative, technical and teaching investment. PMID: 26827272 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - February 2, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Takayasu arteritis].
Authors: Mirault T, Messas E Abstract Takayasu arteritis is a chronic inflammatory vasculitis of unknown origin affecting large vessels, predominantly the aorta and its main branches. Vessel inflammation leads to wall thickening, fibrosis, and stenosis. The lesions are often asymptomatic leading to limb numbness, transient ischemic attack, cardiovascular event and renovascular hypertension. Treatment is based on corticosteroids, immunosuppressant and biologics if necessary. Endovascular treatment and open-surgery can be useful for end-organ ischemia relief. PMID: 26827273 [PubMed - as supplied by publisher] (So...
Source: Revue de Medecine Interne - February 2, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Inherited primitive and secondary polycythemia].
Authors: Barba T, Boileau JC, Pasquet F, Hot A, Pavic M Abstract Myeloproliferative disorders and secondary polycythemia cover most of the polycythemia cases encountered in daily practice. Inherited polycythemias are rare entities that have to be suspected when the classical causes of acquired polycythemia have been ruled out. Recent advances were made in the understanding of these pathologies, which are still little known to the physicians. This review reports the state of knowledge and proposes an algorithm to follow when confronted to a possible case of inherited polycythemia. PMID: 26827274 [PubMed - as sup...
Source: Revue de Medecine Interne - February 2, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Aortitis and surgery].
Authors: Gaudric J, Dennery M, Jouhannet C, Kagan N, Saadoun D, Chiche L, Koskas F Abstract Non-infectious aortitis are usually due to giant cell arteritis (temporal arteritis), Takayasu and Behçet's diseases. Aortitis should be suspected in the presence of aortic wall thickening or of aneurysm or occlusion of the aorta and its branches in the absence of characteristic cardiovascular risk factors. Surgery is required in case of severe damage. But the quiescence of the inflammatory disease must be obtained before endovascular or surgical treatment to prevent complications such as anastomotic false aneurysm or...
Source: Revue de Medecine Interne - January 24, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Early rehospitalization of persons aged 75 years or older admitted to a post-emergency general medicine department: Rates and predictive factors].
CONCLUSION: The rehospitalization of EP is frequent and difficult to anticipate because there are few predictors and their impact is weak. The most important factors were medical: multiple hospitalizations and confusion without dementia. PMID: 26763200 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A chronic cough of unusual cause].
Authors: Bacha S, Zidi A, Racil H, Cheikhrouhou S, Chaouch N, Chabbou A, Megdiche ML PMID: 26774915 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Porphyrias and haem related disorders].
Authors: Peoc'h K, Martin-Schmitt C, Talbi N, Deybach JC, Gouya L, Puy H Abstract The hereditary porphyrias comprise a group of eight metabolic disorders of the haem biosynthesis pathway characterised by acute neurovisceral symptoms, skin lesions or both. Each porphyria is caused by abnormal function of a separate enzymatic step resulting in a specific accumulation of haem precursors. Seven porphyrias are the consequence of a partial enzyme deficiency while a gain of function mechanism has been recently characterised in a novel porphyria. Acute porphyrias present with severe abdominal pain, nausea, constipation, co...
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Up-to-date on the HELLP syndrome (Hemolysis, Elevated Liver enzymes and Low Platelets)].
The objective of this article is to review the pathophysiological and clinical data and current treatment. PMID: 26774917 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Short-course antibiotic regimens: Up-to-date].
We present the available data on frequent infections such as urinary tract infections, community acquired pneumonia, bone and joint infections and intra-abdominal infections. We underline the difficulties to perform such trials and discuss original options to a better evaluation of treatment duration. PMID: 26775641 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Pyogenic brain abscesses in adults].
Authors: de Lastours V, Fantin B Abstract Pyogenic brain abscesses (BA) are rare and their diagnosis may be difficult because of the absence of specific clinical or biological signs. However, the use of diffusion-weighted brain MRI sequences has modified the management of BA, as they are highly sensitive and specific to differentiate pyogenic brain abscesses from necrotic tumors, which are the most frequent differential diagnosis in case of ring-enhancing lesions on CT scan. This new tool allows for a rapid diagnosis and should be followed by a CT-guided aspiration of BA. This safe procedure should be performed if ...
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[An unusual cause of hemoptysis].
Authors: El Aoud S, Mnif F, Lassoued N, Mnif Feki M, Rekik N, Charfi N, Abid M PMID: 26775643 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Multimodal imaging of ischemic heart diseases: A 2015 update].
Authors: Di Marco L, Rosset M, Zhang-Yin J, Ohana M Abstract Current realities and future possibilities of imaging in the ischemic heart diseases are very broad and constantly evolving, with the improvement of existing technologies and the introduction of new features such as dual-energy CT, strain ultrasound, multimodality fusion or perfusion MRI. Regular collaboration between prescribing clinicians, cardiologists, radiologists and nuclear radiologists is therefore essential to tailor the examination to the specific clinical question. The indications for each modality will therefore depend on its diagnostic perfor...
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Brown tumor as an exceptional origin of lumbocruralgia with favourable outcome].
CONCLUSION: Although uncommon, brown tumor should be a diagnosis to consider in their presence of a spinal tumor. The improvement after conservative treatment could be dramatic. PMID: 26775645 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A chronic inflammatory response syndrome of unusual cause].
Authors: Coutier F, Gil H, Tavernier L, Humbert S, Méaux-Ruault N, Magy-Bertrand N PMID: 26776765 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Aortitis in giant cell arteritis].
Authors: Schmidt J, Duhaut P Abstract Aortitis is a frequent complication of giant cell arteritis. Imaging techniques can reveal the inflammation of the aortic wall. CT-scan can show circumferential aortic wall thickening, or TEP-scan can show aortic FDG-uptake. Aortic aneurysm and dissection is a feared but probably rare complication of the inflammation of the aortic wall during GCA. Screening for aortitis could be proposed for patients with symptoms of aortic involvement, for patients with signs of large vessels involvement (limb claudication, bruit) or for patients with incomplete response to treatment. The best...
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Giant cell arteritis: Commentary on recommendations of the French Study Group for Large Vessel Vasculitis (GEFA).
Authors: Hoffman GS PMID: 26781693 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 20, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Post-menopausal osteoporosis: Up-to-date].
Authors: Briot K, Roux C Abstract Patients with a high risk of fragility fractures, and those with recent fractures, must receive the highest priority for anti-osteoporotic treatment, because of the consequences of some of these fractures (hip, vertebrae, pelvis, humerus). Both non pharmacological and pharmacological treatments must be used. The duration of the treatment is based on the assessment of fracture risk. PMID: 26723850 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 13, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[An axillary discomfort].
Authors: Vignes S, Arrault M PMID: 26724895 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 13, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[A rare cause of relapsing acute abdominal pain].
Authors: Galmiche S, Hanslik T PMID: 26725942 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 13, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Disseminated bone lesions].
Authors: Allain JS, Bernard M, Icard N, Gatey C, Molina JM, Tas P, Leyer C, Fillatre P, Tattevin P, Houot R PMID: 26725943 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 13, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Gut microbiota: Description, role and pathophysiologic implications].
Authors: Landman C, Quévrain E Abstract The human gut contains 10(14) bacteria and many other micro-organisms such as Archaea, viruses and fungi. Studying the gut microbiota showed how this entity participates to gut physiology and beyond this to human health, as a real "hidden organ". In this review, we aimed to bring information about gut microbiota, its structure, its roles and its implication in human pathology. After bacterial colonization in infant, intestinal microbial composition is unique for each individual although more than 95% can be assigned to four major phyla. The use of cultur...
Source: Revue de Medecine Interne - January 13, 2016 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Telemedicine in thrombotic microangiopathies: A way forward in rare diseases requiring emergency care].
Authors: Coppo P, Corre E, Rondeau E, Benhamou Y, Bachet A, Stépanian A, Veyradier A, Centre de référence des microangiopathies thrombotiques Abstract Thrombotic microangiopathies (TMA) represent rare diseases requiring a high skill for their management that deserved in France the identification of a dedicated National reference center. TMA are short-term life-threatening diseases; however, with an adapted management, their prognosis can be excellent. It is therefore mandatory to recognize and treat them rapidly according to standard guidelines. Telemedicine is a specialized hub consisting of h...
Source: Revue de Medecine Interne - December 20, 2015 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Hyperammonemic encephalopathy as the presenting feature of a relapsing multiple myeloma].
CONCLUSION: Hyperammonemic encephalopathy is a rare complication of multiple myeloma and is associated with high in-patient mortality. To our knowledge, this is the first case of hyperammonemic encephalopathy due to a relapsing myeloma diagnosed and treated in intensive care unit. PMID: 26681106 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - December 20, 2015 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

[Use of Twitter(®) in a congress: First experience for French internal medicine].
CONCLUSION: This experience emphasizes the fact that Twitter(®) improves interactions during congresses. Therefore, we should continue on a going forward basis to develop this tool. PMID: 26653331 [PubMed - as supplied by publisher] (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - December 16, 2015 Category: Internal Medicine Tags: Rev Med Interne Source Type: research