Among adults with cardiovascular disease and BMI ≥27kg/m < sup > 2 < /sup > but no diabetes, does semaglutide lower risk of cardiovascular mortality, myocardial infarction, or stroke when compared with placebo, and is it safe?
Rev Med Interne. 2024 Jan 15:S0248-8663(24)00007-9. doi: 10.1016/j.revmed.2024.01.006. Online ahead of print.NO ABSTRACTPMID:38228454 | DOI:10.1016/j.revmed.2024.01.006 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 16, 2024 Category: Internal Medicine Authors: L Lanthier M-F Langlois M- É Plourde M Cauchon Source Type: research
What's new in hyperkalemia management?
Rev Med Interne. 2024 Jan 13:S0248-8663(24)00004-3. doi: 10.1016/j.revmed.2024.01.004. Online ahead of print.ABSTRACTHyperkalemia is common in everyday clinical practice, and is a major risk factor for mortality. It mainly affects patients with chronic renal failure (CKD), diabetes or receiving treatment with inhibitors of the renin-angiotensin-aldosterone system (iRAAS). Therapeutic management aims not only to avoid the complications of hyperkalemia, but also to avoid discontinuation of cardio- and nephroprotective treatments such as iRAAS. The use of polystyrene sulfonate, widely prescribed, is often limited by patient a...
Source: Revue de Medecine Interne - January 14, 2024 Category: Internal Medicine Authors: F Lefevre C Mousseaux M Bobot Source Type: research
French protocol for the diagnosis and management of hematopoietic stem cell transplantation in autoimmune diseases
Rev Med Interne. 2024 Feb;45(2):79-99. doi: 10.1016/j.revmed.2023.12.008. Epub 2024 Jan 13.ABSTRACTHematopoietic stem cell transplantation (HSCT) for severe ADs was developed over the past 25years and is now validated by national and international medical societies for severe early systemic sclerosis (SSc) and relapsing-remitting multiple sclerosis (MS) and available as part of routine care in accredited center. HSCT is also recommended, with varying levels of evidence, as an alternative treatment for several ADs, when refractory to conventional therapy, including specific cases of connective tissue diseases or vasculitis,...
Source: Revue de Medecine Interne - January 14, 2024 Category: Internal Medicine Authors: D Farge G Pugnet M Allez C Castilla-Llorente E Chatelus P Cintas C Faucher-Barbey P Labauge C Labeyrie B Lioure A Maria D Michonneau M Puyade M Talouarn L Terriou X Treton G Wojtasik H Zephir Z Marjanovic MATHEC collaborators Source Type: research
Clinical characteristics and follow-up of 60 patients with recent diagnosis of giant cell arteritis, NEWTON study
CONCLUSION: Despite the increasing use of TCZ in the therapeutic arsenal and of the PET/CT in the imaging tools of GCA patients, relapses and complications of corticosteroid therapy remain frequent, observed in more than a third of patients.PMID:38216390 | DOI:10.1016/j.revmed.2023.12.005 (Source: Revue de Medecine Interne)
Source: Revue de Medecine Interne - January 12, 2024 Category: Internal Medicine Authors: L Goncalves V-T Tran J Chauffier V Bourdin K Nassarmadji A Vanjak W Bigot R Burlacu K Champion A Lopes A Depont B A Borrero O Mangin H Adle-Biassette P Bonnin A Boutigny S Bonnin L Neumann S Mouly D S ène C Comarmond Source Type: research
Myocardial Infarction with no obstructive coronary arteries: Imaging plays a central role
Rev Med Interne. 2023 Dec 29:S0248-8663(23)00765-8. doi: 10.1016/j.revmed.2023.10.455. Online ahead of print.ABSTRACTMyocardial infarction with non-obstructive coronary lesion (MINOCA) represents a non-negligible percentage of the proportion of myocardial infarctions (≈6%). Moreover, the long-term prognosis is poor, with an annual mortality rate of 2%. This high mortality rate may be explained by the fact that MINOCA represents a heterogeneous group, and the diagnosis of pathology is poorly understood. It is essential to be aware of this clinical presentation, and to follow the different diagnostic strategies, in order t...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: B Sedoud G Barone-Rochette Source Type: research
L ’haploinsuffisance de A20 : que doit connaître le clinicien?
Rev Med Interne. 2023 Dec 29:S0248-8663(23)01321-8. doi: 10.1016/j.revmed.2023.12.004. Online ahead of print.ABSTRACTA20 Haploinsufficiency (HA20) is a monogenic autoinflammatory disease associated with an autosomal dominant mutation in the TNFAIP3 gene. It induces a defect in the inactivation of the pro-inflammatory NF-κB pathway. Less than 200 cases have been described worldwide. The clinical picture of the disease is essentially based on the association of recurrent fever and/or biologic inflammatory syndrome, aphtosis, often bipolar, and cutaneous folliculitis. However, the clinical spectrum of HA20 is very broad, inc...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: I Elhani A Aouba Q Riller H Vergneault G Boursier F Rieux-Laucat V Hentgen S Georgin-Lavialle Source Type: research
Myocardial Infarction with no obstructive coronary arteries: Imaging plays a central role
Rev Med Interne. 2023 Dec 29:S0248-8663(23)00765-8. doi: 10.1016/j.revmed.2023.10.455. Online ahead of print.ABSTRACTMyocardial infarction with non-obstructive coronary lesion (MINOCA) represents a non-negligible percentage of the proportion of myocardial infarctions (≈6%). Moreover, the long-term prognosis is poor, with an annual mortality rate of 2%. This high mortality rate may be explained by the fact that MINOCA represents a heterogeneous group, and the diagnosis of pathology is poorly understood. It is essential to be aware of this clinical presentation, and to follow the different diagnostic strategies, in order t...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: B Sedoud G Barone-Rochette Source Type: research
L ’haploinsuffisance de A20 : que doit connaître le clinicien?
Rev Med Interne. 2023 Dec 29:S0248-8663(23)01321-8. doi: 10.1016/j.revmed.2023.12.004. Online ahead of print.ABSTRACTA20 Haploinsufficiency (HA20) is a monogenic autoinflammatory disease associated with an autosomal dominant mutation in the TNFAIP3 gene. It induces a defect in the inactivation of the pro-inflammatory NF-κB pathway. Less than 200 cases have been described worldwide. The clinical picture of the disease is essentially based on the association of recurrent fever and/or biologic inflammatory syndrome, aphtosis, often bipolar, and cutaneous folliculitis. However, the clinical spectrum of HA20 is very broad, inc...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: I Elhani A Aouba Q Riller H Vergneault G Boursier F Rieux-Laucat V Hentgen S Georgin-Lavialle Source Type: research
Myocardial Infarction with no obstructive coronary arteries: Imaging plays a central role
Rev Med Interne. 2023 Dec 29:S0248-8663(23)00765-8. doi: 10.1016/j.revmed.2023.10.455. Online ahead of print.ABSTRACTMyocardial infarction with non-obstructive coronary lesion (MINOCA) represents a non-negligible percentage of the proportion of myocardial infarctions (≈6%). Moreover, the long-term prognosis is poor, with an annual mortality rate of 2%. This high mortality rate may be explained by the fact that MINOCA represents a heterogeneous group, and the diagnosis of pathology is poorly understood. It is essential to be aware of this clinical presentation, and to follow the different diagnostic strategies, in order t...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: B Sedoud G Barone-Rochette Source Type: research
L ’haploinsuffisance de A20 : que doit connaître le clinicien?
Rev Med Interne. 2023 Dec 29:S0248-8663(23)01321-8. doi: 10.1016/j.revmed.2023.12.004. Online ahead of print.ABSTRACTA20 Haploinsufficiency (HA20) is a monogenic autoinflammatory disease associated with an autosomal dominant mutation in the TNFAIP3 gene. It induces a defect in the inactivation of the pro-inflammatory NF-κB pathway. Less than 200 cases have been described worldwide. The clinical picture of the disease is essentially based on the association of recurrent fever and/or biologic inflammatory syndrome, aphtosis, often bipolar, and cutaneous folliculitis. However, the clinical spectrum of HA20 is very broad, inc...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: I Elhani A Aouba Q Riller H Vergneault G Boursier F Rieux-Laucat V Hentgen S Georgin-Lavialle Source Type: research
Myocardial Infarction with no obstructive coronary arteries: Imaging plays a central role
Rev Med Interne. 2023 Dec 29:S0248-8663(23)00765-8. doi: 10.1016/j.revmed.2023.10.455. Online ahead of print.ABSTRACTMyocardial infarction with non-obstructive coronary lesion (MINOCA) represents a non-negligible percentage of the proportion of myocardial infarctions (≈6%). Moreover, the long-term prognosis is poor, with an annual mortality rate of 2%. This high mortality rate may be explained by the fact that MINOCA represents a heterogeneous group, and the diagnosis of pathology is poorly understood. It is essential to be aware of this clinical presentation, and to follow the different diagnostic strategies, in order t...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: B Sedoud G Barone-Rochette Source Type: research
L ’haploinsuffisance de A20 : que doit connaître le clinicien?
Rev Med Interne. 2023 Dec 29:S0248-8663(23)01321-8. doi: 10.1016/j.revmed.2023.12.004. Online ahead of print.ABSTRACTA20 Haploinsufficiency (HA20) is a monogenic autoinflammatory disease associated with an autosomal dominant mutation in the TNFAIP3 gene. It induces a defect in the inactivation of the pro-inflammatory NF-κB pathway. Less than 200 cases have been described worldwide. The clinical picture of the disease is essentially based on the association of recurrent fever and/or biologic inflammatory syndrome, aphtosis, often bipolar, and cutaneous folliculitis. However, the clinical spectrum of HA20 is very broad, inc...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: I Elhani A Aouba Q Riller H Vergneault G Boursier F Rieux-Laucat V Hentgen S Georgin-Lavialle Source Type: research
Myocardial Infarction with no obstructive coronary arteries: Imaging plays a central role
Rev Med Interne. 2023 Dec 29:S0248-8663(23)00765-8. doi: 10.1016/j.revmed.2023.10.455. Online ahead of print.ABSTRACTMyocardial infarction with non-obstructive coronary lesion (MINOCA) represents a non-negligible percentage of the proportion of myocardial infarctions (≈6%). Moreover, the long-term prognosis is poor, with an annual mortality rate of 2%. This high mortality rate may be explained by the fact that MINOCA represents a heterogeneous group, and the diagnosis of pathology is poorly understood. It is essential to be aware of this clinical presentation, and to follow the different diagnostic strategies, in order t...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: B Sedoud G Barone-Rochette Source Type: research
L ’haploinsuffisance de A20 : que doit connaître le clinicien?
Rev Med Interne. 2023 Dec 29:S0248-8663(23)01321-8. doi: 10.1016/j.revmed.2023.12.004. Online ahead of print.ABSTRACTA20 Haploinsufficiency (HA20) is a monogenic autoinflammatory disease associated with an autosomal dominant mutation in the TNFAIP3 gene. It induces a defect in the inactivation of the pro-inflammatory NF-κB pathway. Less than 200 cases have been described worldwide. The clinical picture of the disease is essentially based on the association of recurrent fever and/or biologic inflammatory syndrome, aphtosis, often bipolar, and cutaneous folliculitis. However, the clinical spectrum of HA20 is very broad, inc...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: I Elhani A Aouba Q Riller H Vergneault G Boursier F Rieux-Laucat V Hentgen S Georgin-Lavialle Source Type: research
Myocardial Infarction with no obstructive coronary arteries: Imaging plays a central role
Rev Med Interne. 2023 Dec 29:S0248-8663(23)00765-8. doi: 10.1016/j.revmed.2023.10.455. Online ahead of print.ABSTRACTMyocardial infarction with non-obstructive coronary lesion (MINOCA) represents a non-negligible percentage of the proportion of myocardial infarctions (≈6%). Moreover, the long-term prognosis is poor, with an annual mortality rate of 2%. This high mortality rate may be explained by the fact that MINOCA represents a heterogeneous group, and the diagnosis of pathology is poorly understood. It is essential to be aware of this clinical presentation, and to follow the different diagnostic strategies, in order t...
Source: Revue de Medecine Interne - December 30, 2023 Category: Internal Medicine Authors: B Sedoud G Barone-Rochette Source Type: research
