Monitoring maternal triglyceride concentrations during pregnancy could be useful in reducing perinatal mortality
AbstractWe read with great interest the article byhttps://obgyn.onlinelibrary.wiley.com/action/doSearch?ContribAuthorStored=Sauvegrain,+PriscilleSauvegrain et al. entitled “Understanding high rates of stillbirth and neonatal death in a disadvantaged, high ‐migrant district in France: a perinatal audit”.1 This well ‐designed study confirmed again that maternal overweight/obesity increases perinatal mortality. We would like to address some points that merit further attention. The intrauterine environment can affect the long‐term health of the offspring has been widely accepted. Maternal high pre‐pregnancy...
Source: Acta Obstetricia et Gynecologica Scandinavica - March 31, 2020 Category: OBGYN Authors: Rui ‐Hong Xue, Xian‐hua Lin, Dan‐dan Wu, He‐Feng Huang Tags: LETTER TO EDITOR Source Type: research

Sanofi, Regeneron Expand Testing of Potential Coronavirus Treatment
(Reuters)—Sanofi and Regeneron Pharmaceuticals Inc. have expanded a clinical trial of their rheumatoid arthritis drug Kevzara (sarilumab) as a coronavirus treatment to patients outside the U.S. The companies said enrolments for the mid-to-late stage trial of sarilumab, an immune-system modifying drug known as a monoclonal antibody, have now started in Italy, Spain, Germany, France, Canada... [Read More] (Source: The Rheumatologist)
Source: The Rheumatologist - March 31, 2020 Category: Rheumatology Authors: Reuters Staff Tags: Drug Updates clinical trials COVID-19 Regeneron Pharmaceuticals Inc. Sanofi sarilumab Source Type: research

Modeling favipiravir antiviral efficacy against emerging viruses: from animal studies to clinical trials
AbstractIn 2014, our research network was involved in the evaluation of favipiravir, an anti ‐Influenza polymerase inhibitor, against Ebola virus. In this review we discuss how mathematical modelling was used, first to propose a relevant dosing regimen in humans, and then to optimize its antiviral efficacy in a non‐human primate (NHP) model. The data collected in NHPs were finally used to develop a model of Ebola pathogenesis integrating the interactions between the virus, the innate and adaptive immune response and the action of favipiravir. We conclude the review of this work by discussing how these results are of re...
Source: CPT: Pharmacometrics and Systems Pharmacology - March 31, 2020 Category: Drugs & Pharmacology Authors: Vincent Madelain, France Mentr é, Sylvain Baize, Xavier Anglaret, Cédric Laouénan, Lisa Oestereich, Thi Huyen Tram Nguyen, Denis Malvy, Géraldine Piorkowski, Frederik Graw, Stephan Günther, Hervé Raoul, Xavier de Lamballerie, Jérémie Tags: REVIEW ARTICLE Source Type: research

Polymorphism of the alpha-1-fucosyltransferase (FUT1) gene in several wild boar (Sus scrofa) populations in France and link to edema disease
Publication date: Available online 29 March 2020Source: Research in Veterinary ScienceAuthor(s): Geoffrey Petit, Vladimir Grosbois, Karine Chalvet-Monfray, Alain Ducos, Daniel Desmecht, Guy-Pierre Martineau, Anouk Decors (Source: Research in Veterinary Science)
Source: Research in Veterinary Science - March 31, 2020 Category: Veterinary Research Source Type: research

Dose-dense adjuvant chemotherapy in early breast cancer patients: 15-year results of the Phase 3 Mammella InterGruppo (MIG)-1 study
British Journal of Cancer, Published online: 31 March 2020; doi:10.1038/s41416-020-0816-8Dose-dense adjuvant chemotherapy in early breast cancer patients: 15-year results of the Phase 3 Mammella InterGruppo (MIG)-1 study (Source: British Journal of Cancer)
Source: British Journal of Cancer - March 31, 2020 Category: Cancer & Oncology Authors: Eva Blondeaux Matteo Lambertini Andrea Michelotti Benedetta Conte Marco Benasso Chiara Dellepiane Claudia Bighin Simona Pastorino Alessia Levaggi Alessia D ’ Alonzo Francesca Poggio Giulia Buzzatti Chiara Molinelli Piero Fregatti Sergio Bertoglio France Source Type: research

Gastric bypass but not sleeve gastrectomy increases risk of major osteoporotic fracture: French population ‐based cohort study
ConclusionsIn patients aged 40 ‐65, gastric bypass but not sleeve gastrectomy or the other procedures increased risk of major osteoporotic fractures.This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - March 30, 2020 Category: Orthopaedics Authors: Julien Paccou, Niels Martign ène, Eric Lespessailles, Evgéniya Babykina, François Pattou, Bernard Cortet, Grégoire Ficheur Tags: Original Article Source Type: research

X-ray characterization of self-standing bent Si crystal plates for Large Hadron Collider beam extraction
Bent crystals can be used to deflect high-energy charged particles for beam extraction and/or beam collimation at accelerator facilities, thanks to the channelling phenomenon. In the present paper, two perfect silicon mono-crystals were bent using two different methods: sandblasting and the application of a carbon fibre composite. In particular, these samples were obtained for the realization of bent crystal prototypes to be used to steer the 7   TeV proton beam of the Large Hadron Collider in the context of the CRYSBEAM project. The two bending methods were selected since they allow a very homogeneous curvature of the c...
Source: Journal of Applied Crystallography - March 30, 2020 Category: Physics Authors: Camattari, R. Romagnoni, M. Bandiera, L. Bagli, E. Mazzolari, A. Sytov, A. Haaga, S. Kabukcuoglu, M. Bode, S. H ä nschke, D. Danilewsky, A. Baumbach, T. Bellucci, V. Guidi, V. Cavoto, G. Tags: self-standing bent crystals hard X-ray diffraction X-ray white-beam topography channelling Large Hadron Collider LHC beam extraction research papers Source Type: research

A new 12-French plastic stent for unresectable distal malignant biliary obstruction
Conclusions This new 12-Fr plastic stent could be an effective and cheaper alternative to SEMSs in distal malignant biliary obstruction. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Endoscopy)
Source: Endoscopy - March 30, 2020 Category: Gastroenterology Authors: Deprez, Pierre H. Moreels, Tom G. Aouattah, Tarik Piessevaux, Hubert P érez-Cuadrado-Robles, Enrique Tags: Innovations and brief communications Source Type: research

Approach to sexuality and sexual dysfunction by reproductive doctors in France
Publication date: Available online 28 March 2020Source: SexologiesAuthor(s): P. Langlade, C. Martin, G. Robin, S. Catteau-Jonard (Source: Sexologies)
Source: Sexologies - March 29, 2020 Category: Sexual Medicine Source Type: research

100. Estrogen Cream for Vulvovaginal Symptoms localized to the Clitoris
We report a series of prepubertal patients for whom topical estrogen cream, applied to the clitoral prepuce, successfully resolved the discomfort. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 29, 2020 Category: OBGYN Authors: Jessica Shim, Katherine Hayes, Amanda French Source Type: research

111. A Non-Healing Wound in an Unusual Location Due to Poor Vulvar Hygiene
We present a case of a wound in an unusual location caused by poor hygiene, and the challenges of treatment. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 29, 2020 Category: OBGYN Authors: Katherine Hayes, Amanda French Source Type: research

60. Knowledge of Anorectal Malformations and Associated Gynecologic Care: A Survey of Obstetrician/Gynecologists
Anorectal malformations (ARMs) occur in about 1 in 4000 live births. After birth, these anomalies are most commonly managed by pediatric colorectal surgeons, although there are a growing number of centers utilizing a multi-disciplinary approach that includes urologists and gynecologists. As these patients become adults, all will require gynecologic care and many will require obstetrical care. We hypothesized that ob/gyns have minimal knowledge and low confidence levels with respect to reproductive care needs for patients with ARMs. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 29, 2020 Category: OBGYN Authors: Katherine Hayes, Amanda French Source Type: research

74. A Large Mass and an Even Larger Discussion: Management of a Serous Borderline Ovarian Tumor in a Trans-male Adolescent
We present the case of a 17-year-old transgender male with acute adnexal torsion of a serous borderline ovarian tumor with androgen receptor positivity to highlight the decision making surrounding ongoing surveillance and gender affirming care for this patient and others like him. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - March 29, 2020 Category: OBGYN Authors: Katherine Hayes, Amanda French Source Type: research

French recommendations for the management of patients with spinal cord injury or at risk of spinal cord injury
Publication date: Available online 27 March 2020Source: Anaesthesia Critical Care & Pain MedicineAuthor(s): A. Roquilly, B. Vigué, M. Boutonnet, P. Bouzat, K. Buffenoir, E. Cesareo, A. Chauvin, C. Court, F. Cook, A.C. de Crouy, P. Denys, J. Duranteau, S. Fuentes, T. Gauss, T. Geeraerts, C. Laplace, V. Martinez, J.F. Payen, B. Perrouin-Verbe, A. Rodrigues (Source: Anaesthesia, Critical Care and Pain Medicine)
Source: Anaesthesia, Critical Care and Pain Medicine - March 28, 2020 Category: Anesthesiology Source Type: research

The Value of H3K27me3 Immunohistochemistry in Differentiating Malignant Peripheral Nerve Sheath Tumour with Its Histologic Mimickers.
Authors: Mustapar N, Zawawi MSF, Tuan Sharif SE Abstract BACKGROUND: Diagnosis of malignant peripheral nerve sheath tumor (MPNST) is rather challenging due to its divergent morphologic heterogeneity and lack of specific ancillary test. The emergence of H3K27 trimethylation (H3K27me3) as a new immunohistochemistry (IHC) marker for MPNST have recently available to assist pathologists in differentiating MPNST from other histologic mimics. We aim to study the expression pattern of H3K27me3 in MPNST and its histologic mimickers and their association with the clinicopathological data. METHODOLOGY: A total of 59 benig...
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Abord de la sexualité et des dysfonctions sexuelles par les médecins de la reproduction en France
Publication date: Available online 27 March 2020Source: SexologiesAuthor(s): P. Langlade, C. Martin, G. Robin, S. Catteau-Jonard (Source: Sexologies)
Source: Sexologies - March 28, 2020 Category: Sexual Medicine Source Type: research

La profession de sexologue en France en 2019 : résultats préliminaires d’une enquête nationale
Publication date: Available online 26 March 2020Source: SexologiesAuthor(s): A. Giami, S. Michaels (Source: Sexologies)
Source: Sexologies - March 28, 2020 Category: Sexual Medicine Source Type: research

Sexology as a profession in France: Preliminary results of a national survey (2019)
Publication date: Available online 26 March 2020Source: SexologiesAuthor(s): A. Giami, S. Michaels (Source: Sexologies)
Source: Sexologies - March 28, 2020 Category: Sexual Medicine Source Type: research

Digestive Neuroendocrine Neoplasms (NEN): French Intergroup clinical practice guidelines for diagnosis, treatment and follow-up (SNFGE, GTE, RENATEN, TENPATH, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, SFR)
This document is a summary of the French Intergroup guidelines regarding the management of digestive neuroendocrine neoplasms (NEN) published in February 2020 (www.tncd.org). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - March 28, 2020 Category: Gastroenterology Authors: Louis de Mestier, Come Lepage, Eric Baudin, Romain Coriat, Fr édéric Courbon, Anne Couvelard, Christine Do Cao, Eric Frampas, Sébastien Gaujoux, Rodica Gincul, Pierre Goudet, Catherine Lombard-Bohas, Gilles Poncet, Denis Smith, Philippe Ruszniewski, Th Tags: Guidelines Source Type: research

Monitoring Transmissibility and Mortality of COVID-19 in Europe
The continued outbreak of coronavirus disease 2019 (COVID-19) in Europe is a significant public health concern. Several European countries have reported imported cases of COVID-19 from Italy, the epicenter in Europe. Local transmission of COVID-19 has been confirmed in certain European countries. As of 10 March 2020, confirmed cases of COVID-19 have reached 10,000 in Italy, exceeded 1,000 in Spain, France, and Germany, and grew quickly in other European countries. (WHO, 2020) In terms of deaths caused by COVID-19, more than 800 were reported in Italy, approximately 50 were reported in Spain and France, but only 3 were repo...
Source: International Journal of Infectious Diseases - March 28, 2020 Category: Infectious Diseases Authors: Jing Yuan, Minghui Li, Gang Lv, Z. Kevin Lu Source Type: research

Pelvic Venous Disease: Identifying This Commonly Overlooked Cause of Chronic Pelvic Pain in Women
This article aims to ensure nurse practitioners are well equipped to recognize women presenting with symptoms suggestive of PVD and expedite referral when needed for further evaluation. (Source: The Journal for Nurse Practitioners)
Source: The Journal for Nurse Practitioners - March 28, 2020 Category: Nursing Authors: Sandra French, Stephen Daugherty, Susan Thul Tags: Feature Article Source Type: research

IJERPH, Vol. 17, Pages 2273: Health Literacy among Health and Social Care University Students
The objective of this study was to define the health literacy levels of students from the Universities of Girona and Barcelona (Spain) and the Regional Institute of Social Work in Perpignan (France). A cross-sectional study was conducted among students of Nursing, Social Work, Primary Education and Special Education in the 2017–2018 academic year. Sociodemographic and academic variables were considered and the HLS-EU-Q16 questionnaire was used to study health literacy levels. In total, 219 students with an average age of 24.9 participated. Of these, 64.4% were studying Social Work, 23.7% Nursing, 5.9% Primary...
Source: International Journal of Environmental Research and Public Health - March 27, 2020 Category: Environmental Health Authors: Juviny à-Canal Su ñer-Soler Porquet Vernay Blanchard Bertran-Noguer Tags: Article Source Type: research

Study of ultrasound-guided needle aspiration and catheter drainage in the management of liver abscesses
ConclusionBoth procedures are equally efficacious in the management of liver abscesses; however in view of less duration of hospital stay, patient safety and comfort, procedure simplicity, and the reduced cost, needle aspiration should be used as the first-line procedure in the treatment of liver abscess (even in abscesses more than 5  cm). Catheter drainage should be reserved for cases that do not respond to a second attempt of aspiration. (Source: Journal of Ultrasound)
Source: Journal of Ultrasound - March 27, 2020 Category: Radiology Source Type: research

Asking questions changes health-related behaviour: An updated systematic review and meta-analysis
This study aims to update a systematic review of randomised controlled trials investigating the question-behaviour effect, in light of several large pre-registered studies being published. (Source: Journal of Clinical Epidemiology)
Source: Journal of Clinical Epidemiology - March 27, 2020 Category: Epidemiology Authors: Lisa M. Miles, Angela M. Rodrigues, Falko F. Sniehotta, David P. French Tags: Review Source Type: research

Three decades of data on phytoplankton and phycotoxins on the French coast: Lessons from REPHY and REPHYTOX
Publication date: Available online 26 March 2020Source: Harmful AlgaeAuthor(s): Catherine Belin, Dominique Soudant, Zouher Amzil (Source: Harmful Algae)
Source: Harmful Algae - March 26, 2020 Category: Environmental Health Source Type: research

Breech presentation: Clinical practice guidelines from the French College of Gynaecologists and Obstetricians (CNGOF)
Publication date: Available online 25 March 2020Source: European Journal of Obstetrics & Gynecology and Reproductive BiologyAuthor(s): Loïc Sentilhes, Thomas Schmitz, Elie Azria, Denis Gallot, Guillaume Ducarme, Diane Korb, Aurélien Mattuizzi, Olivier Parant, Nicolas Sananès, Sophie Baumann, Patrick Rozenberg, Marie-Victoire Sénat, Eric Verspyck (Source: European Journal of Obstetrics and Gynecology and Reproductive Biology)
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - March 26, 2020 Category: OBGYN Source Type: research

Personal, biomechanical, psychosocial, and organizational risk factors for carpal tunnel syndrome: a structural equation modeling approach
This longitudinal study aimed at exploring the direct and indirect relationships between organizational, psychosocial, biomechanical, and personal factors and carpal tunnel syndrome (CTS) in French workers. Between 2002 and 2005, 3710 workers were included in the Cosali cohort. Between 2007 and 2010, 1611 workers were re-examined using the same standardized clinical protocol. Subjects free from CTS at baseline were studied (804 men and 563 women). We used structural equation models to examine the relationships between incident CTS cases and organizational (machine-paced work or work pace dependent on customers' demand), ps...
Source: Pain - March 26, 2020 Category: Anesthesiology Tags: Research Paper Source Type: research

Under-Age Children Returning From Jihadist Group Operation Areas: How Can We Make a Diagnosis and Construct a Narrative With a Fragmentary Anamnesis?
This article is the result of clinical interviews conducted with 53 patients evaluated and taken care of at Avicenne Hospital in Bobigny. To our knowledge, no studies have been published on this subject.ResultsA total of 32 evaluations have been completed, all of which indicated the need for care for these children. Of these children, 64% are under 5 years old, and 59% were born in France. Their clinical profiles are heterogeneous and fluctuate with time.DiscussionThe multiple adverse events experienced by these children and the uniqueness of children born to families suspected by authorities of having participated in acti...
Source: Frontiers in Psychiatry - March 26, 2020 Category: Psychiatry Source Type: research

IJERPH, Vol. 17, Pages 2242: Pathological Traits Associated to Facebook and Twitter among French Users
This study highlights the relationship between depression, anxiety, stress, pathological personality traits, and problematic Facebook and Twitter use. Significant differences have been retrieved between these two uses and their relationship to psychopathology. Future research should also explore the causal relationship between social networking sites use and psychopathology and consider gender. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - March 26, 2020 Category: Environmental Health Authors: Verseilli é Laconi Chabrol Tags: Article Source Type: research

The pioneer ophthalmologist Johann Friedrich Horner (1831-1886) and the clinical anatomy of the homonymous syndrome.
In conclusion, J .F .Horner's adamantine character, hard work, assiduous teaching and skills in eye surgery made him one of the main contributors for the evolution of ophthalmology in the 19th century Central Europe. PMID: 32204671 [PubMed - as supplied by publisher] (Source: Acta Chirurgica Belgica)
Source: Acta Chirurgica Belgica - March 25, 2020 Category: Surgery Tags: Acta Chir Belg Source Type: research

Management in primary care at the time of a suicide attempt and its impact on care post-suicide attempt: an observational study in the French GP sentinel surveillance system
We aimed to describe primary care management at the time of a suicide attempt (SA) and after the SA. (Source: BMC Family Practice)
Source: BMC Family Practice - March 25, 2020 Category: Primary Care Authors: Nadia Younes, Mathieu Rivi ère, Frédéric Urbain, Romain Pons, Thomas Hanslik, Louise Rossignol, Christine Chan Chee and Thierry Blanchon Tags: Research article Source Type: research

Evaluation of the NG-Test MCR-1 Lateral Flow Assay and EDTA-Colistin Broth Disk Elution Methods To Detect Plasmid-Mediated Colistin Resistance among Gram-Negative Bacterial Isolates [Bacteriology]
Plasmid-mediated colistin resistance (PMCR) is a global public health concern, given its ease of transmissibility. The purpose of this study was to evaluate two methods for the detection of PMCR from bacterial colonies: (i) the NG-Test MCR-1 lateral flow immunoassay (LFA; NG Biotech, Guipry, France) and (ii) the EDTA-colistin broth disk elution (EDTA-CBDE) screening test method. These methods were evaluated using a cohort of contemporary, clinical Gram-negative bacillus isolates from 3 U.S. academic medical centers (126 isolates of the Enterobacterales, 50 Pseudomonas aeruginosa isolates, and 50 Acinetobacter species isola...
Source: Journal of Clinical Microbiology - March 25, 2020 Category: Microbiology Authors: Fenwick, A. J., Bergman, Y., Lewis, S., Yee, R., Uhlemann, A.-C., Cole, N., Kohner, P., Ordak, C., Green, D. A., Schuetz, A. N., Humphries, R., Simner, P. J. Tags: Bacteriology Source Type: research

Evaluation of the Revogene Carba C Assay for Detection and Differentiation of Carbapenemase-Producing Gram-Negative Bacteria [Bacteriology]
The Revogene Carba C assay (formerly GenePOC Carba assay) is a multiplex nucleic acid-based in vitro diagnostic test intended for the detection of carbapenemase-producing Enterobacterales (CPE) from cultured colonies. This assay was evaluated directly on colonies of 118 well-characterized Enterobacterales with reduced susceptibility to carbapenems and on 49 multidrug-resistant (MDR) Pseudomonas aeruginosa and 40 MDR Acinetobacter baumannii isolates. The Revogene Carba C assay’s performance was high, as it was able to detect the five major carbapenemases (NDM, VIM, IMP, KPC, and OXA-48). In Enterobacterales, sensitivi...
Source: Journal of Clinical Microbiology - March 25, 2020 Category: Microbiology Authors: Girlich, D., Laguide, M., Dortet, L., Naas, T. Tags: Bacteriology Source Type: research

Evaluation of six commercial kits for the serological diagnosis of Mediterranean visceral leishmaniasis
Conclusions/SignificanceThis is the first study that compared commercially available kits for VL serodiagnosis in the endemic region of the Mediterranean basin. It provides specific information about the tests ’ performance to help clinicians and biologists to select the right assay for VL screening. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 25, 2020 Category: Tropical Medicine Authors: Maude F. L évêque Source Type: research

Prehospital Shock Precautions on Triage (PSPoT) score to assess in-hospital mortality for septic shock
We report the association between The Prehospital Shock Precautions on Triage (PSPoT) score, and in-hospital mortality of SS patients initially cared for in th e prehospital setting by a mobile ICU (MICU). (Source: The American Journal of Emergency Medicine)
Source: The American Journal of Emergency Medicine - March 25, 2020 Category: Emergency Medicine Authors: Romain Jouffroy, Jean Pierre Tourtier, Pascal Philippe, Emmanuel Bloch-Laine, Vincent Bounes, Papa Gueye-Ngalgou, Benoit Vivien Source Type: research

Breech presentation: Clinical practice guidelines from the French College of Gynaecologists and Obstetricians (CNGOF)
To determine the optimal management of singleton fetuses in breech presentation. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 25, 2020 Category: OBGYN Authors: Lo ïc Sentilhes, Thomas Schmitz, Elie Azria, Denis Gallot, Guillaume Ducarme, Diane Korb, Aurélien Mattuizzi, Olivier Parant, Nicolas Sananès, Sophie Baumann, Patrick Rozenberg, Marie-Victoire Sénat, Eric Verspyck Tags: Review article Source Type: research

Recent changes of invasive meningococcal disease in France: arguments to revise the vaccination strategy in view of those of other countries
. (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - March 25, 2020 Category: Allergy & Immunology Authors: Muhamed-Kheir Taha Jo ël Gaudelus Ala-Eddine Deghmane Fran çois Caron Source Type: research

Death audits and reviews for reducing maternal, perinatal and child mortality.
CONCLUSIONS: A complex intervention including maternal death audit and review, as well as development of local leadership and training, probably reduces inpatient maternal mortality in low-income country district hospitals, and probably slightly improves quality of care. Perinatal death audit and review, as part of a complex intervention with training, probably improves quality of care, as measured by perinatal morbidity related to suboptimal care, in a high-income setting where mortality was already very low. The WHO recommends that maternal and perinatal death reviews should be conducted in all hospitals globally. Howeve...
Source: Cochrane Database of Systematic Reviews - March 25, 2020 Category: General Medicine Authors: Willcox ML, Price J, Scott S, Nicholson BD, Stuart B, Roberts NW, Allott H, Mubangizi V, Dumont A, Harnden A Tags: Cochrane Database Syst Rev Source Type: research

Neurodevelopment at age 2 and umbilical artery Doppler in cases of preterm birth after prenatal hypertensive disorder or suspected fetal growth restriction: the EPIPAGE 2 prospective population-based cohort study.
CONCLUSION: Among children born before 32 weeks of gestation because of suspected fetal growth restriction or hypertensive disorder who survived until age 2, prenatal ARED in the umbilical artery was associated with more frequent moderate or severe neuromotor or sensory disabilities. This article is protected by copyright. All rights reserved. PMID: 32212388 [PubMed - as supplied by publisher] (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - March 25, 2020 Category: Radiology Authors: Delorme P, Kayem G, Lorthe E, Sentilhes L, Zeitlin J, Subtil D, Rozé JC, Vayssière C, Durox M, Ancel PY, Pierrat V, Goffinet F, EPIPAGE2 Obstetrical Study Group Tags: Ultrasound Obstet Gynecol Source Type: research

Optical design of the visible telescope for the SVOM mission
This paper describes the optical design of the visible telescope (VT), which is the primary payload for the Chinese-French Space-based ... (Source: Applied Optics)
Source: Applied Optics - March 24, 2020 Category: Physics Authors: Xuewu Fan Gangyi Zou Yulei Qiu Zhihai Pang Hui Zhao Qinfang Chen Yue Pan Hao Yuan Source Type: research

Qualitative Assessment of Adult Patients ’ Perception of Atopic Dermatitis Using Natural Language Processing Analysis in a Cross-Sectional Study
ConclusionsQualitative data from NLP, being more patient-centric than data from clinical standardized measures, provide a more comprehensive view of the burden of AD to inform disease management. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - March 24, 2020 Category: Dermatology Source Type: research

The ICAReB Platform: A Human Biobank for the < i > Institut Pasteur < /i > and Beyond
The ICAReB platform of Institut Pasteur provides access to human bio-resources for academic and private research teams worldwide, essentially in the fields of infection, immunity and neurosciences. More than 134,000 human quality controlled, duly annotated samples (mainly whole-blood derived products, but also stool, urine, saliva, swabs ….), from both healthy and diseased cohorts with open, regulated access, are available upon request. Both clinical investigation and biobanking activities are certified following ISO 9001:2015 and NF S96-900:2011 standards, respectively. ICAReB is a member of PIBnet (Pasteur Interna...
Source: Open Journal of Bioresources - March 24, 2020 Category: Biotechnology Source Type: research

Newborn Screening for Biliary Atresia
Biliary atresia is a serious pediatric liver disease. It is among the leading causes of newborn cholestasis, the foremost reason for cirrhosis and liver-related death in children, and the most frequent indication for liver transplant in the pediatric population. The condition results from an idiopathic, rapidly progressive, fibrosclerosing obliterative injury to large bile ducts during the first months of life. Although not an inherited disease, biliary atresia is a rare orphan liver disease that occurs in 1:15  000 to 1:20 000 live births in North America and Western Europe, with the highest incidence rates in Asia (1...
Source: JAMA - March 24, 2020 Category: General Medicine Source Type: research

The epidemiology and management of stroke in French Guiana
French Guiana has the highest incidence of ischemic and hemorrhagic stroke of all French territories. However, there is no further information on the epidemiology and management of stroke in French Guiana. Our... (Source: BMC Neurology)
Source: BMC Neurology - March 24, 2020 Category: Neurology Authors: D évi Rita Rochemont, Emmanuelle Mimeau, Caroline Misslin-Tritsch, Martine Papaix-Puech, Emmanuel Delmas, Yannick Bejot, Bertrand DeToffol, Isabelle Fournel and Mathieu Nacher Tags: Research article Source Type: research

High Prevalence of ST131 Subclades C2-H30Rx and C1-M27 Among Extended-Spectrum β-Lactamase-Producing Escherichia coli Causing Human Extraintestinal Infections in Patients From Two Hospitals of Spain and France During 2015
The present study was carried out to evaluate the prevalence of sequence type 131 (ST131) among 188 extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) collected in 2015 in Lucus Augusti University hospital (Lugo, Spain) and AP-HP Beaujon hospital (Clichy, France) with regard to other STs and to characterize, the types of ESBL produced, serotypes, virulence factor (VF)-encoding genes and the ST131 clades and subclades. ST131 was detected in 33 (39.1%) and 46 (47.9%) of the isolates in Lucus Augusti and Beaujon, respectively. The 109 remaining isolates displayed 57 other STs, the following STs being disp...
Source: Frontiers in cellular and infection microbiology - March 24, 2020 Category: Microbiology Source Type: research

Cancers, Vol. 12, Pages 768: 30 Years of Experience in the Management of Stage III and IV Epithelial Ovarian Cancer: Impact of Surgical Strategies on Survival
Conclusion: In our 30 years&amp;rsquo; experience of EOC management, complete resection rate was the only independent factor that significantly improved OS and PFS, regardless of the surgical strategy. (Source: Cancers)
Source: Cancers - March 24, 2020 Category: Cancer & Oncology Authors: Berenice Delga Jean-Marc Classe Gilles Houvenaeghel Guillaume Blache Laura Sabiani Houssein El Hajj Nicole Andrieux Eric Lambaudie Tags: Article Source Type: research

Disorders of Sex Development Are an Emerging Problem in French Bulldogs: A Description of Six New Cases and a Review of the Literature.
In conclusion, we postulate that the description of the sexual phenotype of DSD females (enlarged clitoris and presence of testicular tissue) does not distinguish between hereditary XX DSD and nonhereditary freemartinism. Cytogenetic and molecular analyses are thus necessary to correctly diagnose such cases. This is especially important for the French bulldog breed, as a rapid increase in its population could spread hereditary DSD. PMID: 32203972 [PubMed - as supplied by publisher] (Source: Sexual Development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation)
Source: Sexual Development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation - March 24, 2020 Category: Genetics & Stem Cells Authors: Szczerbal I, Nowacka-Woszuk J, Nizanski W, Dzimira S, Ligocka Z, Jastrzebska A, Kabala B, Biernacik M, Przadka P, Switonski M Tags: Sex Dev Source Type: research

Alcohol consumption in relation to carotid subclinical atherosclerosis and its progression: results from a European longitudinal multicentre study
ConclusionIn this European population at high risk of CVD, findings show an inverse relation between moderate alcohol consumption and carotid subclinical atherosclerosis and its 30-month progression, independently of several potential confounders. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - March 24, 2020 Category: Nutrition Source Type: research

Common power laws for cities and spatial fractal structures [Economic Sciences]
City-size distributions are known to be well approximated by power laws across a wide range of countries. But such distributions are also meaningful at other spatial scales, such as within certain regions of a country. Using data from China, France, Germany, India, Japan, and the United States, we first document... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - March 24, 2020 Category: Science Authors: Tomoya Mori, Tony E. Smith, Wen-Tai Hsu Tags: Social Sciences Source Type: research

Molecules, Vol. 25, Pages 1464: Effect of Instant Controlled Pressure-Drop on the Non-Nutritional Compounds of Seeds and Sprouts of Common Black Bean (Phaseolus vulgaris L.)
The objective of this work was to evaluate the change in the non-nutritional composition of bean seeds and sprouts by DIC treatment. The results show that with the germination, the concentration of phenolic and tannin compounds increased 99% and 73%, respectively, as well as the quantity of saponins (65.7%), while phytates and trypsin inhibitors decreased 26% and 42%, respectively. When applying the DIC treatment, the content of phytates (23&amp;ndash;29%), saponins (44%) and oligosaccharides increased in bean sprouts and decreased phenolic compounds (4&amp;ndash;14%), tannins (23% to 72%), and trypsin inhibitors (...
Source: Molecules - March 24, 2020 Category: Chemistry Authors: Anaberta Cardador-Mart ínez Yara Mart ínez-Tequitlalpan Tzayhri Gallardo-Velazquez Xariss M. S ánchez-Chino Jorge Mart ínez-Herrera Luis Jorge Corzo-R íos Cristian Jim énez-Martínez Tags: Article Source Type: research