Epidemiology of myasthenia gravis in France: Incidence, prevalence, and comorbidities based on national healthcare insurance claims data
CONCLUSION: The incidence and prevalence rates of MG are significantly higher than those previously reported in the literature and the incidence increases with age. The excess risk of cancer raises concerns for MG patients, in particular, concerning the management of immunosuppressive drugs.PMID:38582663 | DOI:10.1016/j.neurol.2024.02.392 (Source: Revue Neurologique)
Source: Revue Neurologique - April 6, 2024 Category: Neurology Authors: S Keovilayhong A Mulliez L Feral C Chenaf P Clavelou X Moisset F Taithe L Poncet Megemont Source Type: research

Impact of multiple sclerosis on employment and income: Insights from a random sample representative of private sector employees in France using longitudinal administrative data
In conclusion, this study shows that the effects of MS on the employed population in the private sector occur early in the disease course and are cumulative, and that replacement income helps to reduce the loss of resources thanks to the French health and social system.PMID:38582662 | DOI:10.1016/j.neurol.2024.02.389 (Source: Revue Neurologique)
Source: Revue Neurologique - April 6, 2024 Category: Neurology Authors: E Leray C Regaert E Duguet S Guillaume S Pichetti M Espagnacq Source Type: research

Childhood trauma and alcohol misuse in college students: The moderating role of minimization
CONCLUSION: These findings suggest that a tendency to minimize threatening childhood events may specifically be related to increased risk of greater alcohol misuse among college students. Therefore, it may be important for clinician to assess minimization of early events in students with a history of childhood trauma.PMID:38581770 | DOI:10.1016/j.chiabu.2024.106749 (Source: Child Abuse and Neglect)
Source: Child Abuse and Neglect - April 6, 2024 Category: Child Development Authors: G éraldine Tapia Jordan Teysseyre R émi Bréhonnet Alexandra Baud Guillaume Gauvreau Marion Gray Florin Oprescu Source Type: research

Childhood trauma and alcohol misuse in college students: The moderating role of minimization
CONCLUSION: These findings suggest that a tendency to minimize threatening childhood events may specifically be related to increased risk of greater alcohol misuse among college students. Therefore, it may be important for clinician to assess minimization of early events in students with a history of childhood trauma.PMID:38581770 | DOI:10.1016/j.chiabu.2024.106749 (Source: Child Abuse and Neglect)
Source: Child Abuse and Neglect - April 6, 2024 Category: Child Development Authors: G éraldine Tapia Jordan Teysseyre R émi Bréhonnet Alexandra Baud Guillaume Gauvreau Marion Gray Florin Oprescu Source Type: research

Outbreak of carbapenemase-producing < em > Citrobacter farmeri < /em > in an intensive care haematology department linked to a persistent wastewater reservoir in one hospital room, France, 2019 to 2022
Euro Surveill. 2024 Apr;29(14). doi: 10.2807/1560-7917.ES.2024.29.14.2300386.ABSTRACTIn 2019-2022, a prolonged outbreak of oxacillinase (OXA)-48-producing Citrobacter farmeri due to a persistent environmental contamination, occurred in our haematology intensive care unit. In April 2019, we isolated OXA-48-producing C. farmeri from rectal samples of two patients in weekly screenings. The cases had stayed in the same hospital room but 4 months apart. We screened five patients who had stayed in this room between the two cases and identified a third case. Over the following 3 years, five other cases were detected, the last cas...
Source: Euro Surveill - April 5, 2024 Category: Infectious Diseases Authors: Marie Regad Julie Lizon Corentine Alauzet Gabrielle Roth-Guepin Caroline Bonmati Simona Pagliuca Alain Lozniewski Arnaud Florentin Source Type: research

Live birth rates after breast cancer among women who desired a child
DISCUSSION: The non-negligible proportion of live births following spontaneous pregnancy after breast cancer allows us to be reassuring for patients. However, the emergence of new chemotherapy protocols whose consequences on long-term gonadotoxicity are still not well known requires further studies and prompts the promotion of fertility preservation as a precautionary measure.PMID:38580527 | DOI:10.1016/j.bulcan.2024.02.005 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - April 5, 2024 Category: Cancer & Oncology Authors: Pauline Charpentier Mathilde Cavalieri Isabelle Desmoulins Charles Coutant Source Type: research

Sociotropy and video game playing: Massively multiplayer online role-playing games versus other games
DISCUSSION: MMORPG players reported higher psychological distress than players of other game genres. For all players, sociotropy, rather than autonomy, was found to be a predictor of social anxiety symptoms and IGD intensity. Sociotropy and depression explained IGD intensity only for MMORPG players and not for players of other game genres. The social dimension appears to be more prominent among MMORPG players and could be one of the main personality traits predicting this specific internet gaming disorder. The treatment implications for internet gaming disorder are discussed.PMID:38580529 | DOI:10.1016/j.encep.2024.01.005 ...
Source: L Encephale - April 5, 2024 Category: Psychiatry Authors: C édric Plessis Alain Guerrien Emin Altintas Source Type: research

Exavir: implementation and evaluation of experimental pharmacology skills acquisition by pharmacy students
Ann Pharm Fr. 2024 Apr 3:S0003-4509(24)00043-9. doi: 10.1016/j.pharma.2024.03.008. Online ahead of print.ABSTRACTWith the evolution of European and French regulations on animal experimentation in higher education, taking greater account of animal welfare, the University of Angers has developed a virtual animal experimentation software named Exavir. Used for practical work (PW) in physiology, pharmacology and toxicology in the Health, Sciences, and engineering curricula, Exavir can be used to simulate various experiments for teaching purposes, in vivo or ex vivo. Thanks to an original approach integrating serious games with...
Source: Annales Pharmaceutiques Francaises - April 5, 2024 Category: Drugs & Pharmacology Authors: Clara Bourreau Tristan Chevrier Thomas Desserrey Nathalie Lusson Flavien Bessaguet S ébastien Faure Samuel Legeay Source Type: research

Outbreak of carbapenemase-producing < em > Citrobacter farmeri < /em > in an intensive care haematology department linked to a persistent wastewater reservoir in one hospital room, France, 2019 to 2022
Euro Surveill. 2024 Apr;29(14). doi: 10.2807/1560-7917.ES.2024.29.14.2300386.ABSTRACTIn 2019-2022, a prolonged outbreak of oxacillinase (OXA)-48-producing Citrobacter farmeri due to a persistent environmental contamination, occurred in our haematology intensive care unit. In April 2019, we isolated OXA-48-producing C. farmeri from rectal samples of two patients in weekly screenings. The cases had stayed in the same hospital room but 4 months apart. We screened five patients who had stayed in this room between the two cases and identified a third case. Over the following 3 years, five other cases were detected, the last cas...
Source: Euro Surveill - April 5, 2024 Category: Infectious Diseases Authors: Marie Regad Julie Lizon Corentine Alauzet Gabrielle Roth-Guepin Caroline Bonmati Simona Pagliuca Alain Lozniewski Arnaud Florentin Source Type: research

Use of metamizole and other non-opioid analgesics in Switzerland between 2014 and 2019: an observational study using a large health insurance claims database
CONCLUSION: In Switzerland, metamizole was increasingly claimed between 2014 and 2019. Metamizole was most frequently claimed by older adults and patients with comedications suggestive of underlying conditions, which can be worsened or caused by use of nonsteroidal anti-inflammatory drugs. The lack of studies regarding the effectiveness and safety of metamizole in this population warrants further investigation.PMID:38579298 | DOI:10.57187/s.3535 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Stephan Gut Marlene Rauch Manuel Haschke Carola A Huber Jan Gaertner Nadine Schur Christoph R Meier Julia Spoendlin Source Type: research

Exposure of the general French population to metals and metalloids in 2014-2016: Results from the Esteban study
CONCLUSIONS: Esteban provided a nationwide description of 28 metal and metalloid exposure levels for adults (some never measured before) and for the first time in children. The study results highlighted widespread exposure to several metals and metalloids. These results could be used to advocate public health decisions for continued efforts to reduce harmful exposure to toxic metals. The Reference values (RV95) built from Esteban could also be used to support future government strategies.PMID:38579993 | DOI:10.1016/j.envres.2024.118744 (Source: Environmental Research)
Source: Environmental Research - April 5, 2024 Category: Environmental Health Authors: Amivi Oleko Abdessattar Saoudi Abdelkrim Zeghnoun Marie Pecheux Vincent Cirimele Ciprian Mihai Cirtiu G éraldine Berail Emmanuelle Szego S ébastien Denys Cl émence Fillol Source Type: research

Live birth rates after breast cancer among women who desired a child
DISCUSSION: The non-negligible proportion of live births following spontaneous pregnancy after breast cancer allows us to be reassuring for patients. However, the emergence of new chemotherapy protocols whose consequences on long-term gonadotoxicity are still not well known requires further studies and prompts the promotion of fertility preservation as a precautionary measure.PMID:38580527 | DOI:10.1016/j.bulcan.2024.02.005 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - April 5, 2024 Category: Cancer & Oncology Authors: Pauline Charpentier Mathilde Cavalieri Isabelle Desmoulins Charles Coutant Source Type: research

Sociotropy and video game playing: Massively multiplayer online role-playing games versus other games
DISCUSSION: MMORPG players reported higher psychological distress than players of other game genres. For all players, sociotropy, rather than autonomy, was found to be a predictor of social anxiety symptoms and IGD intensity. Sociotropy and depression explained IGD intensity only for MMORPG players and not for players of other game genres. The social dimension appears to be more prominent among MMORPG players and could be one of the main personality traits predicting this specific internet gaming disorder. The treatment implications for internet gaming disorder are discussed.PMID:38580529 | DOI:10.1016/j.encep.2024.01.005 ...
Source: L Encephale - April 5, 2024 Category: Psychiatry Authors: C édric Plessis Alain Guerrien Emin Altintas Source Type: research

Exavir: implementation and evaluation of experimental pharmacology skills acquisition by pharmacy students
Ann Pharm Fr. 2024 Apr 3:S0003-4509(24)00043-9. doi: 10.1016/j.pharma.2024.03.008. Online ahead of print.ABSTRACTWith the evolution of European and French regulations on animal experimentation in higher education, taking greater account of animal welfare, the University of Angers has developed a virtual animal experimentation software named Exavir. Used for practical work (PW) in physiology, pharmacology and toxicology in the Health, Sciences, and engineering curricula, Exavir can be used to simulate various experiments for teaching purposes, in vivo or ex vivo. Thanks to an original approach integrating serious games with...
Source: Annales Pharmaceutiques Francaises - April 5, 2024 Category: Drugs & Pharmacology Authors: Clara Bourreau Tristan Chevrier Thomas Desserrey Nathalie Lusson Flavien Bessaguet S ébastien Faure Samuel Legeay Source Type: research

Outbreak of carbapenemase-producing < em > Citrobacter farmeri < /em > in an intensive care haematology department linked to a persistent wastewater reservoir in one hospital room, France, 2019 to 2022
Euro Surveill. 2024 Apr;29(14). doi: 10.2807/1560-7917.ES.2024.29.14.2300386.ABSTRACTIn 2019-2022, a prolonged outbreak of oxacillinase (OXA)-48-producing Citrobacter farmeri due to a persistent environmental contamination, occurred in our haematology intensive care unit. In April 2019, we isolated OXA-48-producing C. farmeri from rectal samples of two patients in weekly screenings. The cases had stayed in the same hospital room but 4 months apart. We screened five patients who had stayed in this room between the two cases and identified a third case. Over the following 3 years, five other cases were detected, the last cas...
Source: Euro Surveill - April 5, 2024 Category: Infectious Diseases Authors: Marie Regad Julie Lizon Corentine Alauzet Gabrielle Roth-Guepin Caroline Bonmati Simona Pagliuca Alain Lozniewski Arnaud Florentin Source Type: research