Crimean-Congo Hemorrhagic Fever Virus in Ticks Collected from Cattle, Corsica, France, 2023
P. Kiwan et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - April 11, 2024 Category: Infectious Diseases Source Type: research
Genes, Vol. 15, Pages 481: Association between the GLP1R A316T Mutation and Adolescent Idiopathic Scoliosis in French Canadian and Italian Cohorts
alérie Marcil
Studies have revealed anthropometric discrepancies in girls with adolescent idiopathic scoliosis (AIS) compared to non-scoliotic subjects, such as a higher stature, lower weight, and lower body mass index. While the causes are still unknown, it was proposed that metabolic hormones could play a role in AIS pathophysiology. Our objectives were to evaluate the association of GLP1R A316T polymorphism in AIS susceptibility and to study its relationship with disease severity and progression. We performed a retrospective case–control association study with controls and AIS patients from an Italian...
Source: Genes - April 11, 2024 Category: Genetics & Stem Cells Authors: Émilie Normand Anita Franco Stefan Parent Giovanni Lombardi Marco Brayda-Bruno Alessandra Colombini Alain Moreau Val érie Marcil Tags: Article Source Type: research
Efficacy of eculizumab in transplantation-associated thrombotic microangiopathy: results of the French nationwide study on behalf of the SFGM-TC and the CNR-MAT
Bone Marrow Transplantation, Published online: 11 April 2024; doi:10.1038/s41409-024-02279-2Efficacy of eculizumab in transplantation-associated thrombotic microangiopathy: results of the French nationwide study on behalf of the SFGM-TC and the CNR-MAT (Source: Bone Marrow Transplantation)
Source: Bone Marrow Transplantation - April 11, 2024 Category: Hematology Authors: Marion Peyre Flore Sicre de Fontbrune Ana Berceanu Lise Benjemia Martin Castelle Maud D ’Aveni Ambroise Mar çais Eleonore Kaphan Claude-Eric Bulabois Anne Sirvent Pierre-Simon Rohrlich Valerie Coiteux Sylvain Chantepie St éphanie Nguyen-Quoc R égis P Source Type: research
Validation of the definition of rheumatoid arthritis flare based on SDAI and CDAI in clinical practice in two French independent cohorts
New definitions for flares in rheumatoid arthritis (RA) based on the Simplified and Clinical Disease Activity Indices (SDAI, CDAI) have been recently introduced.1 In this article, the authors defined flare as an absolute increase of 4.7 in SDAI and 4.5 in CDAI. Following this proposal we aimed at studying these cut-off values for absolute increases in SDAI and CDAI in diagnosing self-reported flares and treatment escalation in two separate real-world cohorts of patients with RA in France. The first cohort included 101 patients with established RA,2 recruited between May 2016 and February 2018 and annually evaluated in day ...
Source: Annals of the Rheumatic Diseases - April 11, 2024 Category: Rheumatology Authors: Avouac, J., Hecquet, S., Thomas, M., Combier, A., Carves, S., Allanore, Y. Tags: ARD Letter Source Type: research
Do patients with type 2 diabetes mellitus included in randomised clinical trials differ from general-practice patients? A cross-sectional comparative study
Conclusions
Patients with type 2 diabetes mellitus cared for in general practice differ in a number of important aspects from patients included in randomised controlled trials on which clinical practice guidelines are based. This situation hampers the applicability of these guidelines. Future randomised trials should include patients who better fit the ‘average’ general-practice patient with type 2 diabetes mellitus to help improve the translation of study findings in daily practice. (Source: BMJ Open)
Source: BMJ Open - April 11, 2024 Category: General Medicine Authors: Dugard, A., Giraudeau, B., Dibao-Dina, C. Tags: Open access, Diabetes and Endocrinology Source Type: research
Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10 years of follow-up
Thymic epithelial tumours (TET) are rare and malignant tumours of the mediastinum. Due to their rarity, studies inclusion periods are long and treatment modalities have varied across time. Actual recommendations are not robust due to the lack of prospective studies. In addition, thymomas have a slow evolution and large series with a long-term follow-up are scarce [1 –5]. In France, treatment recommendations for the past 10 years, have been based on ESMO (European Society for Medical Oncology) and RYHTMIC (Réseau tumeurs THYMiques et Cancer), a French network mandated to systematically discuss every case of TET in Fran...
Source: Radiotherapy and Oncology - April 11, 2024 Category: Radiology Authors: Hugo Lopez, Angela Botticella, Farid Belkhir, Benjamin Besse, Elie Fadel, Olaf Mercier, Antonin Levy, C écile Le Péchoux Tags: Original Article Source Type: research
Creation of a shared medical decision support tool for the management of abdominal aortic aneurysms
Patients with an unruptured abdominal aortic aneurysm (AAA) at the surgical threshold may benefit from aneurysmal exclusion either by open surgery or endovascular repair. A patient decision aid (PtDA) could be useful to help patients and their surgeons choose between the two techniques. The aim of this study was to develop a shared medical decision support tool, in french language, for the surgical treatment of AAA. (Source: Annals of Vascular Surgery)
Source: Annals of Vascular Surgery - April 11, 2024 Category: Surgery Authors: Marie Dumaus é, Marie Mouillard, Quentin Balézeaux, Eric Ducasse, Caroline Caradu, Yves-Marie Vincent Tags: Clinical Research Source Type: research
Risk factors for emergency surgery for diverticulitis: A retrospective multicentric French study at 41 hospitals
This study aimed to assess the rate and risk factors of emergency surgery for sigmoid diverticulitis. (Source: Surgery)
Source: Surgery - April 11, 2024 Category: Surgery Authors: Camille Godet, Charles Sabbagh, Laura Beyer-Berjot, Mehdi Ouaissi, Philippe Zerbib, Bridoux Val érie, Gilles Manceau, Yves Panis, Etienne Buscail, Aurélien Venara, Iman Khaoudy, Martin Gaillard, Manon Viennet, Alexandre Thobie, Benjamin Menahem, Clariss Source Type: research
Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen
In this study, we aimed to assess the association between helminth exposure to the most prevalent parasitic infections, schistosomiasis, soil transmitted helminths infection and filariasis, and the Ebola virus glycoprotein (EBOV GP) antibody concentration in response to vaccination with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen in African and European participants using samples obtained from three international clinical trials. Methods/Principal findingsWe conducted a study in a subset of participants in the EBL2001, EBL2002 and EBL3001 clinical trials that evaluated the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen against EV...
Source: PLoS Neglected Tropical Diseases - April 11, 2024 Category: Tropical Medicine Authors: Houreratou Barry Source Type: research
Job description and perception of clinical research personnel working in a network of French intensive care units
There is a lack of information about the organisation and management of clinical research personnel in Europe and of their professional activity in intensive care. We therefore conducted a cross-sectional surv... (Source: Critical Care)
Source: Critical Care - April 11, 2024 Category: Intensive Care Authors: Mireille Adda, Claire Dupuis, G érald Gouby, Claude Dubray, Jean Reignier, Bertrand Souweine and Christian Dualé Tags: Research Source Type: research
‘It’s really a horror.’ Bones from across Europe suggest Stone Age ritual killings
In 1984, in France’s Rhône Valley, forensic anthropologist Eric Crubézy found the skeletons of three women in a Stone Age structure built to resemble a grain silo. At the 5600-year-old site, called Saint-Paul-Trois-Châteaux, one woman was lying on her side, her knees slightly bent. The other two were contorted into unnatural positions and hidden beneath a rocky overhang, broken grindstones piled on their bodies. The 25-year-old researcher, just out of medical school, didn’t know what to make of the odd arrangement of bones. “I thought it was unique,” Crubézy recalls.
It wasn’t until 40 years later...
Source: Science of Aging Knowledge Environment - April 10, 2024 Category: Geriatrics Source Type: research
Occupational exposure to organic solvents and the risk of developing testicular germ cell tumors (TESTIS study): Effect of combined exposure assessment on risk estimation
CONCLUSION: The results suggest that some organic solvents might be involved in the pathogenesis of TGCT among occupationally exposed men. The combined use of JEM+SQ+EA seemed to limit misclassification by considering individual exposure variability and is, therefore, an appealing approach to assess occupational exposures in epidemiological studies.PMID:38597023 | DOI:10.5271/sjweh.4161 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Margot Guth Corinne Pilorget Marie Lefevre Astrid Coste Aur élie Danjou Brigitte Dananch é Delphine Praud Olivia P érol Myriam Daudin Marie-Ange Clarotti St éphanie Lattes C éline Bouillon Ad èle Paul Joachim Sch üz Louis Bujan Ann Olsson B éatric Source Type: research
COVID-19 Vaccine Injury Compensation Program: Lessons Learned From a Review of 10 Implementing Countries
This article reviewed the Vaccine Injury Compensation Programs in 10 major countries to present implications for improving the Korean system. Expanding the scope of national accountability is essential to compensate for the consequences of adhering to national policies during public health crises. Therefore, valuable insight can be obtained from examining the systems in Germany, Japan, and Taiwan, which have implemented more relaxed criteria for determining causality in compensation cases; Thailand's system, which provides the mandatory payment of preliminary compensation for damage caused by vaccination; systems in German...
Source: J Korean Med Sci - April 10, 2024 Category: General Medicine Authors: Cho Ryok Kang Young June Choe Seok-Jun Yoon Source Type: research
Occupational exposure to organic solvents and the risk of developing testicular germ cell tumors (TESTIS study): Effect of combined exposure assessment on risk estimation
CONCLUSION: The results suggest that some organic solvents might be involved in the pathogenesis of TGCT among occupationally exposed men. The combined use of JEM+SQ+EA seemed to limit misclassification by considering individual exposure variability and is, therefore, an appealing approach to assess occupational exposures in epidemiological studies.PMID:38597023 | DOI:10.5271/sjweh.4161 (Source: Scandinavian Journal of Work, Environment and Health)
Source: Scandinavian Journal of Work, Environment and Health - April 10, 2024 Category: Occupational Health Authors: Margot Guth Corinne Pilorget Marie Lefevre Astrid Coste Aur élie Danjou Brigitte Dananch é Delphine Praud Olivia P érol Myriam Daudin Marie-Ange Clarotti St éphanie Lattes C éline Bouillon Ad èle Paul Joachim Sch üz Louis Bujan Ann Olsson B éatric Source Type: research
Effects of Anterior Fundoplication on Postoperative Dysphagia and Reflux After Laparoscopic Esophagocardiomyotomy for Pediatric Achalasia
Conclusion: In this largest observation of pediatric achalasia patients, A-fundo appeared clinically insignificant when determining contributors to control GER or exacerbate postoperative dysphagia. A-fundo should not be routinely adopted in children having L-ECM for achalasia without further multicenter analysis but appears beneficial in cases having inadvertent mucosal violation.PMID:38597929 | DOI:10.1089/lap.2023.0415 (Source: Adv Data)
Source: Adv Data - April 10, 2024 Category: Epidemiology Authors: Mary Peyton French Jordan Busing Sari Acra Heidi Chen Laura Stafman Irving Zamora Michael Holzman Harold N Lovvorn Source Type: research
