Unsupervised machine learning for flaw detection in automated ultrasonic testing of carbon fibre reinforced plastic composites
Ultrasonics. 2024 Apr 6;140:107313. doi: 10.1016/j.ultras.2024.107313. Online ahead of print.ABSTRACTThe use of Carbon Fibre Reinforced Plastic (CFRP) composite materials for critical components has significantly surged within the energy and aerospace industry. With this rapid increase in deployment, reliable post-manufacturing Non-Destructive Evaluation (NDE) is critical for verifying the mechanical integrity of manufactured components. To this end, an automated Ultrasonic Testing (UT) NDE process delivered by an industrial manipulator was developed, greatly increasing the measurement speed, repeatability, and locational ...
Source: Ultrasonics - April 11, 2024 Category: Physics Authors: Vedran Tunukovic Shaun McKnight Richard Pyle Zhiming Wang Ehsan Mohseni S Gareth Pierce Randika K W Vithanage Gordon Dobie Charles N MacLeod Sandy Cochran Tom O'Hare Source Type: research
Thulium or holmium laser or both: where will the journey take us?
This article aims to review the key technological differences between Ho:YAG lasers and pulsed thulium lasers and compare/discuss the initial clinical results for stone lithotripsy and laser enucleation.In-vitro studies have demonstrated the technical superiority of TFL compared with Ho:YAG lasers. However, as TFL is still a new technology, only limited studies are available to date, and optimal settings for lithotripsy have not been established. For enucleation, the differences of TFL compared with a high-power Ho:YAG laser seem to be clinically irrelevant. Initial studies on pulsed Tm:YAG lasers show good results, but th...
Source: Aktuelle Urologie - April 11, 2024 Category: Urology & Nephrology Authors: Benedikt Becker Sophia Hook Andreas J Gross Clemens Rosenbaum Simon Filmar Jonas Herrmann Christopher Netsch Source Type: research
Estimation of persistent sodium-current density in rat hippocampal mossy fibre boutons: Correction of space-clamp errors
J Physiol. 2024 Apr 9. doi: 10.1113/JP284657. Online ahead of print.ABSTRACTWe used whole-cell patch clamp to estimate the stationary voltage dependence of persistent sodium-current density (iNaP) in rat hippocampal mossy fibre boutons. Cox's method for correcting space-clamp errors was extended to the case of an isopotential compartment with attached neurites. The method was applied to voltage-ramp experiments, in which iNaP is assumed to gate instantaneously. The raw estimates of iNaP led to predicted clamp currents that were at variance with observation, hence an algorithm was devised to improve these estimates. Optiona...
Source: The Journal of Physiology - April 10, 2024 Category: Physiology Authors: Ricardo Murphy Henrik Alle J örg R P Geiger Johan F Storm Source Type: research
Estimation of persistent sodium-current density in rat hippocampal mossy fibre boutons: Correction of space-clamp errors
J Physiol. 2024 Apr 9. doi: 10.1113/JP284657. Online ahead of print.ABSTRACTWe used whole-cell patch clamp to estimate the stationary voltage dependence of persistent sodium-current density (iNaP) in rat hippocampal mossy fibre boutons. Cox's method for correcting space-clamp errors was extended to the case of an isopotential compartment with attached neurites. The method was applied to voltage-ramp experiments, in which iNaP is assumed to gate instantaneously. The raw estimates of iNaP led to predicted clamp currents that were at variance with observation, hence an algorithm was devised to improve these estimates. Optiona...
Source: The Journal of Physiology - April 10, 2024 Category: Physiology Authors: Ricardo Murphy Henrik Alle J örg R P Geiger Johan F Storm Source Type: research
The discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysis
Recently, carbon quantum dots (CQDs) have been widely used in various fields, especially in the diagnosis and therapy of neurological disorders, due to their excellent prospects. However, the associated inevit... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 10, 2024 Category: Toxicology Authors: Min Chen, Siyuan Chen, Xinyu Wang, Zongjian Ye, Kehan Liu, Yijing Qian, Meng Tang and Tianshu Wu Tags: Research Source Type: research
The structure –function relationship between multifocal pupil perimetry and retinal nerve fibre layer in glaucoma
Multifocal pupillographic objective perimetry (mfPOP) is a novel method for assessing functional change in diseases like glaucoma. Previous research has suggested that, in contrast to the pretectally-mediated ... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - April 10, 2024 Category: Opthalmology Authors: Corinne F. Carle, Allan Y. H. Chain, Maria Kolic and Ted Maddess Tags: Research Source Type: research
The impact of daily supplementation with rhamnogalacturonan-I on the gut microbiota in healthy adults: A randomized controlled trial
Biomed Pharmacother. 2024 Apr 8;174:116561. doi: 10.1016/j.biopha.2024.116561. Online ahead of print.ABSTRACTPectin and its derivatives have been shown to modulate immune signaling as well as gut microbiota in preclinical studies, which may constitute the mechanisms by which supplementation of specific pectic polysaccharides confers protection against viral respiratory infections. In a double-blind, placebo-controlled rhinovirus (RV16) challenge study, healthy volunteers were randomized to consume placebo (0.0 g/day) (N = 46), low-dose (0.3 g/day) (N = 49) or high-dose (1.5 g/day) (N = 51) of carrot derived rhamnogalacturo...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 9, 2024 Category: Drugs & Pharmacology Authors: Ching Jian Nikolaj Sorensen Ren é Lutter Ruud Albers Willem de Vos Anne Salonen Annick Mercenier Source Type: research
Effects of altering diet carbohydrate profile and physical form on zoo ‐housed giraffe Giraffa camelopardalis reticulata
AbstractUnlike wild giraffe that primarily consume low starch browse, the preference of zoo-housed giraffe for consuming supplemental feeds over forage could increase the risk of digestive disorders such as ruminal acidosis. Our objective was to evaluate the effects of modifying a supplemental feed's non-fibre carbohydrate profile and physical form on nutritional, behavioural, and blood measures of giraffe in a zoological setting. Six non-lactating, adult, female reticulated giraffes were used in a two-pen modified reversal study using two dietary treatments in seven 21-day periods with data collected on days 15 –21. Die...
Source: Journal of Animal Physiology and Animal Nutrition - April 9, 2024 Category: Zoology Authors: Celeste C. Kearney,
Ray L. Ball,
Mary Beth Hall Tags: ORIGINAL ARTICLE Source Type: research
CXCR3 < sup > + < /sup > effector regulatory T cells associate with disease tolerance during lower respiratory pneumovirus infection
Immunology. 2024 Apr 7. doi: 10.1111/imm.13790. Online ahead of print.ABSTRACTLifestyle factors like poor maternal diet or antibiotic exposure disrupt early life microbiome assembly in infants, increasing the risk of severe lower respiratory infections (sLRI). Our prior studies in mice indicated that a maternal low-fibre diet (LFD) exacerbates LRI severity in infants by impairing recruitment of plasmacytoid dendritic cells (pDC) and consequently attenuating expansion of lung regulatory T (Treg) cells during pneumonia virus of mice (PVM) infection. Here, we investigated whether maternal dietary fibre intake influences Treg ...
Source: Immunology - April 7, 2024 Category: Allergy & Immunology Authors: Ismail Sebina Sylvia Ngo Ridwan B Rashid Mariah Alorro Patricia Namubiru Daniel Howard Tufael Ahmed Simon Phipps Source Type: research
CXCR3 < sup > + < /sup > effector regulatory T cells associate with disease tolerance during lower respiratory pneumovirus infection
Immunology. 2024 Apr 7. doi: 10.1111/imm.13790. Online ahead of print.ABSTRACTLifestyle factors like poor maternal diet or antibiotic exposure disrupt early life microbiome assembly in infants, increasing the risk of severe lower respiratory infections (sLRI). Our prior studies in mice indicated that a maternal low-fibre diet (LFD) exacerbates LRI severity in infants by impairing recruitment of plasmacytoid dendritic cells (pDC) and consequently attenuating expansion of lung regulatory T (Treg) cells during pneumonia virus of mice (PVM) infection. Here, we investigated whether maternal dietary fibre intake influences Treg ...
Source: Immunology - April 7, 2024 Category: Allergy & Immunology Authors: Ismail Sebina Sylvia Ngo Ridwan B Rashid Mariah Alorro Patricia Namubiru Daniel Howard Tufael Ahmed Simon Phipps Source Type: research
CXCR3 < sup > + < /sup > effector regulatory T cells associate with disease tolerance during lower respiratory pneumovirus infection
Immunology. 2024 Apr 7. doi: 10.1111/imm.13790. Online ahead of print.ABSTRACTLifestyle factors like poor maternal diet or antibiotic exposure disrupt early life microbiome assembly in infants, increasing the risk of severe lower respiratory infections (sLRI). Our prior studies in mice indicated that a maternal low-fibre diet (LFD) exacerbates LRI severity in infants by impairing recruitment of plasmacytoid dendritic cells (pDC) and consequently attenuating expansion of lung regulatory T (Treg) cells during pneumonia virus of mice (PVM) infection. Here, we investigated whether maternal dietary fibre intake influences Treg ...
Source: Immunology - April 7, 2024 Category: Allergy & Immunology Authors: Ismail Sebina Sylvia Ngo Ridwan B Rashid Mariah Alorro Patricia Namubiru Daniel Howard Tufael Ahmed Simon Phipps Source Type: research
Naming fMRI-guided white matter language tract volumes influence naming decline after temporal lobe resection
AbstractObjectiveThe aim of this study was to explore the relation of language functional MRI (fMRI)-guided tractography with postsurgical naming decline in people with temporal lobe epilepsy (TLE).MethodsTwenty patients with unilateral TLE (9 left) were studied with auditory and picture naming functional MRI tasks. Activation maxima in the left posterobasal temporal lobe were used as seed regions for whole-brain fibre tractography. Clinical naming performance was assessed preoperatively, 4 months, and 12 months following temporal lobe resection. Volumes of white matter language tracts in both hemispheres as well as tra...
Source: Journal of Neurology - April 7, 2024 Category: Neurology Source Type: research
The influence of cation exchange on the possible mechanism of erionite toxicity: A synchrotron-based micro-X-ray fluorescence study on THP-1-derived macrophages exposed to erionite-Na
Environ Res. 2024 Apr 4:118878. doi: 10.1016/j.envres.2024.118878. Online ahead of print.ABSTRACTFibrous erionite is the only zeolite classified as Group 1 carcinogen by the International Agency for Research on Cancer (IARC). Carcinogenesis induced by erionite is thought to involve several factors as biopersistence, the iron role and cation exchange processes. To better understand these mechanisms, a detailed investigation at the micro scale was performed, collecting elemental information on iron and cation release and their distribution in biological systems by synchrotron micro-X-ray fluorescence mapping (SR-micro-XRF) a...
Source: Environmental Research - April 6, 2024 Category: Environmental Health Authors: Simona Raneri Alessandra Gianoncelli Valentina Bonanni Serena Mirata Sonia Scarf ì Laura Fornasini Danilo Bersani Debora Baroni Cristiana Picco Alessandro F Gualtieri Source Type: research
The influence of cation exchange on the possible mechanism of erionite toxicity: A synchrotron-based micro-X-ray fluorescence study on THP-1-derived macrophages exposed to erionite-Na
Environ Res. 2024 Apr 4:118878. doi: 10.1016/j.envres.2024.118878. Online ahead of print.ABSTRACTFibrous erionite is the only zeolite classified as Group 1 carcinogen by the International Agency for Research on Cancer (IARC). Carcinogenesis induced by erionite is thought to involve several factors as biopersistence, the iron role and cation exchange processes. To better understand these mechanisms, a detailed investigation at the micro scale was performed, collecting elemental information on iron and cation release and their distribution in biological systems by synchrotron micro-X-ray fluorescence mapping (SR-micro-XRF) a...
Source: Cell Research - April 6, 2024 Category: Cytology Authors: Simona Raneri Alessandra Gianoncelli Valentina Bonanni Serena Mirata Sonia Scarf ì Laura Fornasini Danilo Bersani Debora Baroni Cristiana Picco Alessandro F Gualtieri Source Type: research
The influence of cation exchange on the possible mechanism of erionite toxicity: A synchrotron-based micro-X-ray fluorescence study on THP-1-derived macrophages exposed to erionite-Na
Environ Res. 2024 Apr 4:118878. doi: 10.1016/j.envres.2024.118878. Online ahead of print.ABSTRACTFibrous erionite is the only zeolite classified as Group 1 carcinogen by the International Agency for Research on Cancer (IARC). Carcinogenesis induced by erionite is thought to involve several factors as biopersistence, the iron role and cation exchange processes. To better understand these mechanisms, a detailed investigation at the micro scale was performed, collecting elemental information on iron and cation release and their distribution in biological systems by synchrotron micro-X-ray fluorescence mapping (SR-micro-XRF) a...
Source: Environmental Research - April 6, 2024 Category: Environmental Health Authors: Simona Raneri Alessandra Gianoncelli Valentina Bonanni Serena Mirata Sonia Scarf ì Laura Fornasini Danilo Bersani Debora Baroni Cristiana Picco Alessandro F Gualtieri Source Type: research
