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Mapping innate and adaptive immune function in arbovirus infections.
PMID: 29667753 [PubMed - in process] (Source: Immunology)
Source: Immunology - April 19, 2018 Category: Allergy & Immunology Authors: Altmann DM Tags: Immunology Source Type: research

Mapping the tumour HLA ligandome by mass spectrometry.
This article is protected by copyright. All rights reserved. PMID: 29658117 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - April 15, 2018 Category: Allergy & Immunology Authors: Freudenmann LK, Marcu A, Stevanović S Tags: Immunology Source Type: research

A humanized TCR retaining authentic specificity and affinity conferred potent anti-tumor cytotoxicity.
This article is protected by copyright. All rights reserved. PMID: 29645087 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - April 12, 2018 Category: Allergy & Immunology Authors: Chen L, Tian Y, Zhan K, Chen A, Weng Z, Huang J, Li Y, Sun Y, Zheng H, Li Y Tags: Immunology Source Type: research

Impacts of microbiome metabolites on immune regulation and autoimmunity.
This article is protected by copyright. All rights reserved. PMID: 29637999 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - April 11, 2018 Category: Allergy & Immunology Authors: Haase S, Haghikia A, Wilck N, Müller DN, Linker RA Tags: Immunology Source Type: research

Deficient Arginase II Expression without Alteration in Arginase I Expression Attenuated Experimental Autoimmune Encephalomyelitis in Mice.
In conclusion, Arg II was identified as a factor promoting EAE likely via an Arg I-independent mechanism. Arg II may promote EAE by enhancing DC production of Th17-differentiating cytokines. Specific inhibition of Arg II could be a potential therapy for MS. This article is protected by copyright. All rights reserved. PMID: 29574762 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 25, 2018 Category: Allergy & Immunology Authors: Choudry M, Tang X, Santorian T, Wasnik S, Xiao J, Xing W, Lau KW, Mohan S, Baylink DJ, Qin X Tags: Immunology Source Type: research

Antibody repertoire analysis in polygenic autoimmune diseases.
Abstract High-throughput sequencing of the DNA/RNA encoding antibody heavy and light chains is rapidly transforming the field of adaptive immunity. It can address key questions including (i) how the B-cell repertoire differs in health and disease and (ii) if it does differ, the point(s) in B-cell development at which this occurs. The advent of technologies, such as whole genome sequencing, offers the chance to link abnormalities in the B-cell antibody repertoire to specific genomic variants and polymorphisms. Here, we discuss the current research using B-cell antibody repertoire sequencing in three polygenic autoi...
Source: Immunology - March 25, 2018 Category: Allergy & Immunology Authors: Bashford-Rogers RJM, Smith KGC, Thomas DC Tags: Immunology Source Type: research

The roles of resident, central and effector memory CD4 T cells in protective immunity following infection or vaccination.
This article is protected by copyright. All rights reserved. PMID: 29570776 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 23, 2018 Category: Allergy & Immunology Authors: Gray JI, Westerhof LM, MacLeod MKL Tags: Immunology Source Type: research

Defining the role of NK cells during dengue virus infection.
This article is protected by copyright. All rights reserved. PMID: 29570783 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 23, 2018 Category: Allergy & Immunology Authors: Mathew A Tags: Immunology Source Type: research

Immune regulation by microbiome metabolites.
This article is protected by copyright. All rights reserved. PMID: 29569377 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 22, 2018 Category: Allergy & Immunology Authors: Kim CH Tags: Immunology Source Type: research

Antigen-specific airway IL-33 production depends on Fc γR-mediated incorporation of the antigen by alveolar macrophages in sensitized mice.
This article is protected by copyright. All rights reserved. PMID: 29569388 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 22, 2018 Category: Allergy & Immunology Authors: Nabe T, Matsuda M, Ishida T, Tsujimoto N, Kido H, Kanaya H, Takahashi H, Takemoto N, Nomura M, Ishihara K, Akiba S, Mizutani N Tags: Immunology Source Type: research

Innate-like CD8+ T cells and NK cells: converging functions and phenotypes.
This article is protected by copyright. All rights reserved. PMID: 29542114 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 14, 2018 Category: Allergy & Immunology Authors: Kurioka A, Klenerman P, Willberg C Tags: Immunology Source Type: research

Murine neutrophils treated with alphaB-crystallin reduce IL-12p40 production by dendritic cells.
This article is protected by copyright. All rights reserved. PMID: 29532462 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 13, 2018 Category: Allergy & Immunology Authors: Finlay TM, Palmer AL, Ousman SS Tags: Immunology Source Type: research

NK Cell Cytotoxicity And Its Regulation By Inhibitory Receptors.
This article is protected by copyright. All rights reserved. PMID: 29512837 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 7, 2018 Category: Allergy & Immunology Authors: Kumar S Tags: Immunology Source Type: research

Regulation of autoimmune and anti-tumour T cell responses by PTPN22.
This article is protected by copyright. All rights reserved. PMID: 29512901 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 7, 2018 Category: Allergy & Immunology Authors: Brownlie RJ, Zamoyska R, Salmond RJ Tags: Immunology Source Type: research

EBV transformation induces overexpression of hMSH2/3/6 on B lymphocytes and enhances γδT cell-mediated cytotoxicity via TCR and NKG2D.
This article is protected by copyright. All rights reserved. PMID: 29512904 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 7, 2018 Category: Allergy & Immunology Authors: Yu-Mei D, Liu HY, Liu YF, Zhang Y, He W Tags: Immunology Source Type: research

Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate-associated disease but not T cell-associated autoimmunity.
In conclusion, we report here that high salt intake affects both lymphoid and myeloid cells ex vivo. However, the effects of high salt intake in vivo seem less pronounced in terms of CD4+ T cell responses, whereas macrophage-dependent pathologies are significantly influenced. This article is protected by copyright. All rights reserved. PMID: 29513375 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 7, 2018 Category: Allergy & Immunology Authors: Vaartjes D, Nandakumar KS, Holmdahl R, Raposo B Tags: Immunology Source Type: research

Inflammation in CNS Neurodegenerative Diseases.
This article is protected by copyright. All rights reserved. PMID: 29513402 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 7, 2018 Category: Allergy & Immunology Authors: Stephenson J, Nutma E, van der Valk P, Amor S Tags: Immunology Source Type: research

Immune responses in stroke: How the immune system contributes to damage and healing after stroke and how this knowledge could be translated to better cures?
This article is protected by copyright. All rights reserved. PMID: 29494762 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - March 1, 2018 Category: Allergy & Immunology Authors: Rayasam A, Hsu M, Kijak JA, Kissel L, Hernandez G, Sandor M, Fabry Z Tags: Immunology Source Type: research

Corrigendum.
Authors: PMID: 29392768 [PubMed - in process] (Source: Immunology)
Source: Immunology - February 4, 2018 Category: Allergy & Immunology Tags: Immunology Source Type: research

Immune modulatory effects of statins.
This article is protected by copyright. All rights reserved. PMID: 29392731 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - February 2, 2018 Category: Allergy & Immunology Authors: Zeiser R Tags: Immunology Source Type: research

The Role of Gut Microbiome and Associated Metabolome in the Regulation of Neuroinflammation in Multiple Sclerosis and Its Implications in Attenuating Chronic Inflammation in Other Inflammatory and Autoimmune Disorders.
This article is protected by copyright. All rights reserved. PMID: 29392733 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - February 2, 2018 Category: Allergy & Immunology Authors: Dopkins N, Nagarkatti PS, Nagarkatti M Tags: Immunology Source Type: research

Cholera toxin enhances IL-17A production in both CD4+ and CD8+ cells via a cAMP/PKA-mediated IL-17A promoter activation.
In conclusion, our data suggest that CT induces an IL-17A-dominated immune microenvironment via cAMP/PKA/CREB signaling pathway. Our study also highlights the potentials of CT and cAMP in modulating Th17 responses in vivo. This article is protected by copyright. All rights reserved. PMID: 29377102 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 27, 2018 Category: Allergy & Immunology Authors: Tsa HC, Velichko S, Lee S, Wu R Tags: Immunology Source Type: research

Daily very low UV dose exposure enhances adaptive immunity, compared with a single high dose exposure. Consequences on the control of a skin infection.
This article is protected by copyright. All rights reserved. PMID: 29377107 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 27, 2018 Category: Allergy & Immunology Authors: Cela EM, Gonzalez CD, Friedrich A, Ledo C, Paz ML, Leoni J, Gomez MI, González Maglio DH Tags: Immunology Source Type: research

Galectin-3 is an amplifier of the interleukin-1 β-mediated inflammatory response in corneal keratinocytes.
This article is protected by copyright. All rights reserved. PMID: 29359328 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 22, 2018 Category: Allergy & Immunology Authors: Uchino Y, Woodward AM, Mauris J, Peterson K, Verma P, Nilsson UJ, Rajaiya J, Argüeso P Tags: Immunology Source Type: research

Origins of Natural Killer Cell Memory: Special Creation or Adaptive Evolution.
This article is protected by copyright. All rights reserved. PMID: 29355919 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 21, 2018 Category: Allergy & Immunology Authors: Holder KA, Comeau EM, Grant MD Tags: Immunology Source Type: research

Inhibition of the FGL2:Fc γRIIB/RIII Immunosuppressive Pathway Enhances Antiviral T cell and B Cell Responses Leading to Clearance of LCMV cl-13.
This article is protected by copyright. All rights reserved. PMID: 29341118 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 17, 2018 Category: Allergy & Immunology Authors: Klingberg O, Khattar R, Farrokhi K, Ferri D, Yavorska N, Zhang J, Sadozai H, Adeyi O, Chruscinski A, Levy GA, Selzner N Tags: Immunology Source Type: research

Adaptive Immune Education by Gut Microbiota Antigens.
This article is protected by copyright. All rights reserved. PMID: 29338074 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 16, 2018 Category: Allergy & Immunology Authors: Zhao Q, Elson CO Tags: Immunology Source Type: research

Hypoxia Inducible Transcription Factors, HIF1A and HIF2A, Increase in Aging Mucosal Tissues.
This article is protected by copyright. All rights reserved. PMID: 29338076 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 16, 2018 Category: Allergy & Immunology Authors: Ebersole JL, Novak MJ, Orraca L, Martinez-Gonzalez J, Kirakodu S, Chen KC, Stromberg A, Gonzalez OA Tags: Immunology Source Type: research

Importance of B cells to development of Tregs and prolongation of tissue allograft survival in recipients receiving autologous bone marrow transplantation.
This article is protected by copyright. All rights reserved. PMID: 29338084 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 16, 2018 Category: Allergy & Immunology Authors: Gorczynski RM, Farrokhi K, Gorczynski C, Sadozai H, Zhu F, Khatri I Tags: Immunology Source Type: research

Combination therapy of lovastatin and AMPK activator improves mitochondrial and peroxisomal functions and clinical disease in EAE model.
This article is protected by copyright. All rights reserved. PMID: 29331024 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 13, 2018 Category: Allergy & Immunology Authors: Singh I, Samuvel DJ, Choi S, Saxena N, Singh AK, Won J Tags: Immunology Source Type: research

Neutrophil infiltration to the brain is platelet-dependent, and is reversed by blockade of platelet GPIb α.
This article is protected by copyright. All rights reserved. PMID: 29325217 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 11, 2018 Category: Allergy & Immunology Authors: Giles JA, Greenhalgh AD, Denes A, Nieswandt B, Coutts G, McColl BW, Allan SM Tags: Immunology Source Type: research

Acute Stimulation Generates Tim-3-expressing Th1-type CD4 T Cells That Persist In Vivo and Show Enhanced Effector Function.
This article is protected by copyright. All rights reserved. PMID: 29315553 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 9, 2018 Category: Allergy & Immunology Authors: Gorman JV, Colgan JD Tags: Immunology Source Type: research

Autoimmunity and autoimmune comorbidities in psoriasis.
This article is protected by copyright. All rights reserved. PMID: 29315555 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 9, 2018 Category: Allergy & Immunology Authors: Furue K, Ito T, Tsuji G, Kadono T, Nakahara T, Furue M Tags: Immunology Source Type: research

Improved methods for predicting peptide binding affinity to MHC class II molecules.
This article is protected by copyright. All rights reserved. PMID: 29315598 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 6, 2018 Category: Allergy & Immunology Authors: Jensen KK, Andreatta M, Marcatili P, Buus S, Greenbaum JA, Yan Z, Sette A, Peters B, Nielsen M Tags: Immunology Source Type: research

Regulatory B cells in Experimental Stroke.
This article is protected by copyright. All rights reserved. PMID: 29313944 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 3, 2018 Category: Allergy & Immunology Authors: Seifert HA, Vandenbark AA, Offner H Tags: Immunology Source Type: research

Human dendritic cell subsets: an update.
This article is protected by copyright. All rights reserved. PMID: 29313948 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 3, 2018 Category: Allergy & Immunology Authors: Collin M, Bigley V Tags: Immunology Source Type: research

P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells.
This article is protected by copyright. All rights reserved. PMID: 29297928 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - January 3, 2018 Category: Allergy & Immunology Authors: Choi J, Pease DR, Chen S, Zhang B, Phee H Tags: Immunology Source Type: research

Resident intestinal eosinophils constitutively express antigen presentation markers and include two phenotypically distinct subsets of eosinophils.
This article is protected by copyright. All rights reserved. PMID: 29281125 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 27, 2017 Category: Allergy & Immunology Authors: Xenakis JJ, Howard ED, Smith KM, Olbrich CL, Huang Y, Anketell D, Maldonado S, Cornwell EW, Spencer LA Tags: Immunology Source Type: research

CD70 encoded by modified vaccinia virus Ankara enhances CD8 T cell dependent protective immunity in MHC class II-deficient mice.
This article is protected by copyright. All rights reserved. PMID: 29281850 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 27, 2017 Category: Allergy & Immunology Authors: Bathke B, Pätzold J, Kassub R, Giessel R, Lämmermann K, Hinterberger M, Brinkmann K, Chaplin P, Suter M, Hochrein H, Lauterbach H Tags: Immunology Source Type: research

Hepatitis C virus core protein reduces CD8+ T-cell proliferation, perforin production and degranulation but increases STAT5 activation.
This article is protected by copyright. All rights reserved. PMID: 29266204 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 20, 2017 Category: Allergy & Immunology Authors: Khan ST, Karges W, Cooper CL, Crawley AM Tags: Immunology Source Type: research

Using immunocompromised mice to identify mechanisms of Zika virus transmission and pathogenesis.
This article is protected by copyright. All rights reserved. PMID: 29266213 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 20, 2017 Category: Allergy & Immunology Authors: Winkler CW, Peterson KE Tags: Immunology Source Type: research

Critical involvement of atypical chemokine receptor CXCR7 in allergic airway inflammation.
This article is protected by copyright. All rights reserved. PMID: 29250768 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 18, 2017 Category: Allergy & Immunology Authors: Chang HC, Huang PH, Syu FS, Hsieh CH, Chang SL, Lu J, Chen HC Tags: Immunology Source Type: research

Alemtuzumab depletion failure can occur in multiple sclerosis.
This article is protected by copyright. All rights reserved. PMID: 29247512 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 16, 2017 Category: Allergy & Immunology Authors: Dubuisson N, Baker D, Kang AS, Pryce G, Marta M, Visser LH, Hofmann WE, Gnanapavan S, Giovannoni G, Schmierer K Tags: Immunology Source Type: research

Intrahepatic and peripheral blood phenotypes of NK and T cells: Differential surface expression of KIR receptors.
This article is protected by copyright. All rights reserved. PMID: 29247515 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 16, 2017 Category: Allergy & Immunology Authors: Podhorzer A, Machicote A, Belen S, Lauferman L, Imventarza O, Montal S, Marciano S, Galdame O, Podesta LG, Fainboim L Tags: Immunology Source Type: research

Review: Current priorities in the Zika response.
This article is protected by copyright. All rights reserved. PMID: 29243225 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 15, 2017 Category: Allergy & Immunology Authors: Esposito DLA, Ballico de Moraes J, Antonio Lopes da Fonseca B Tags: Immunology Source Type: research

Endoplasmic reticulum stress induced Lox-1+ CD15+ polymorphonuclear myeloid-derived suppressor cells in hepatocellular carcinoma.
CONCLUSION: LOX-1+ CD15+ PMN-MDSC were elevated in HCC patients and suppressed T cell proliferation through ROS/Arg I pathway induced by ER stress. They presented positive association with the prognosis of HCC patients. This article is protected by copyright. All rights reserved. PMID: 29211299 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 6, 2017 Category: Allergy & Immunology Authors: Jiang N, Xing YF, Hu B, Tang JX, Dong HM, He YM, Ruan DY, Ye QJ, Cai JR, Ma XK, Chen J, Cai XR, Lin ZX, Wu XY, Li X Tags: Immunology Source Type: research

Evaluating anti-disease immunity to malaria and implications for vaccine design.
This article is protected by copyright. All rights reserved. PMID: 29211303 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 6, 2017 Category: Allergy & Immunology Authors: Ademolue TW, Awandare GA Tags: Immunology Source Type: research

Exosomes from heat-stressed tumor cells inhibit tumor growth by converting regulatory T cells to Th17 cells via IL-6.
This article is protected by copyright. All rights reserved. PMID: 29197065 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - December 2, 2017 Category: Allergy & Immunology Authors: Guo D, Chen Y, Wang S, Yu L, Shen Y, Zhong H, Yang Y Tags: Immunology Source Type: research

CD38 modulates respiratory syncytial virus-driven pro-inflammatory processes in human monocyte-derived dendritic cells.
This article is protected by copyright. All rights reserved. PMID: 29178427 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - November 27, 2017 Category: Allergy & Immunology Authors: Schiavoni I, Scagnolari C, Horenstein AL, Leone P, Pierangeli A, Malavasi F, Ausiello CM, Fedele G Tags: Immunology Source Type: research

Different IL-17-secreting TLR(+) T cell subsets are associated with disease activity in multiple sclerosis.
In conclusion, our data suggest that the expansion of different Th17 phenotypes expressing TLR2, 4 and 9 is associated with MS disease activity, and reveals a preferential ability of TLR2 ligand in directly inducing the production of cytokines related to brains lesions and neurological disabilities. This article is protected by copyright. All rights reserved. PMID: 29168181 [PubMed - as supplied by publisher] (Source: Immunology)
Source: Immunology - November 23, 2017 Category: Allergy & Immunology Authors: Ferreira TB, Hygino J, Wing AC, Kasahara TM, Sacramento PM, Camargo S, Rueda F, Alves-Leon SV, Alvarenga R, Vasconcelos CC, Agrawal A, Gupta S, Bento CAM Tags: Immunology Source Type: research