Editorial.
PMID: 32726840 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Authors: Merseburger AS Tags: Aktuelle Urol Source Type: research

[Rapid Progress in the treatment of bladder cancer: recent achievements].
PMID: 32726841 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Authors: Kramer MW, Bolenz C Tags: Aktuelle Urol Source Type: research

Kurzzeit-An ämietherapie vor Herzoperation senkt Transfusionsrisiko.
Kurzzeit-Anämietherapie vor Herzoperation senkt Transfusionsrisiko. Aktuelle Urol. 2020 Aug;51(4):318-320 Authors: PMID: 32726842 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Mirabegron bei Kindern mit Spina bifida.
Authors: PMID: 32726843 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Peyronie-Krankheit: Neues Traktionsger ät effektiv und sicher.
Peyronie-Krankheit: Neues Traktionsgerät effektiv und sicher. Aktuelle Urol. 2020 Aug;51(4):322-325 Authors: PMID: 32726844 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Inkontinenz nach radikaler Zystektomie mit orthotoper Ileum-Neoblase.
Authors: PMID: 32726845 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Langzeitergebnisse nach Burch-Kolposuspension bzw. autologer Schlingenplastik.
Authors: PMID: 32726846 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Aktuelle Studien zu urologischen Tumoren mit Unterst ützung der AUO.
Aktuelle Studien zu urologischen Tumoren mit Unterstützung der AUO. Aktuelle Urol. 2020 Aug;51(4):329-332 Authors: Rexer H, Hammerer P PMID: 32726847 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Authors: Rexer H, Hammerer P Tags: Aktuelle Urol Source Type: research

Schutz eines Periduralkatheters bei der Hautdesinfektion bei Niereneingriffen.
PMID: 32726848 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Authors: Wiedemann A, Meister T Tags: Aktuelle Urol Source Type: research

Compliance in der Arztpraxis – Fallstricke und Vermeidungsstrategien (Teil 14).
Compliance in der Arztpraxis – Fallstricke und Vermeidungsstrategien (Teil 14). Aktuelle Urol. 2020 Aug;51(4):334-336 Authors: Steinbrück R PMID: 32726849 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Authors: Steinbrück R Tags: Aktuelle Urol Source Type: research

[Paraurethral swelling of unknown origin].
PMID: 32726850 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Authors: Wiedemann A Tags: Aktuelle Urol Source Type: research

Radikale retroperitoneale Nephrektomie.
PMID: 32726851 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - July 31, 2020 Category: Urology & Nephrology Authors: Heidenreich A Tags: Aktuelle Urol Source Type: research

[Current practice patterns of perioperative cystectomy management in Germany: a questionnaire survey].
Abstract OBJECTIVE:  Radical cystectomy (RCX) is the standard treatment for muscle-invasive and treatment-refractory non-invasive bladder cancer, but that is associated with high morbidity. We now survey current practice patterns on perioperative management among German urological departments of all sizes METHODS:  Members of the German Association of Urology and the German Society of Residents in Urology (GeSRU) were contacted by email and asked to answer a 24-item online questionnaire covering clinically relevant aspects of current guidelines and controversies. RESULTS:  Responses were obtain...
Source: Aktuelle Urologie - July 29, 2020 Category: Urology & Nephrology Authors: Dressler FF, Dogan S, Hennig M, Frank T, Struck J, Cebulla A, Salem J, Borgmann H, Klatte T, Kramer MW, Hofbauer S Tags: Aktuelle Urol Source Type: research

[Impact of the experience of urological senior physicians in Germany on professional and personal aspects].
The objective of this study was a comparative analysis of perspectives, private and professional settings, specific job-related activities and individual professional goals of urological senior physicians in Germany based on their experience in this position assessed as number of years (dichotomised at 8 years as senior physician). As part of a cross-sectional study, a 55-item web-based questionnaire was designed, which was sent via a link to members of a mailing list of the German Society of Urology. The survey was available for urological senior physicians between February and April 2019. Group differences were evaluat...
Source: Aktuelle Urologie - July 28, 2020 Category: Urology & Nephrology Authors: Necknig UH, Wolff I, Bründl J, Kriegmair MC, Marghawal D, Wagener N, Hegemann M, Eder E, Wülfing C, Burger M, Leyh H, May M, Kiesewetter J, Weidenbusch M Tags: Aktuelle Urol Source Type: research

[Radical nephrectomy and partial nephrectomy].
Abstract Renal cell carcinoma is the 2nd most frequent urological malignancy in women and the third most frequent in men, with an age peak in the seventh decade of life. If detected early in a local non-metastatic stage, options for complete recovery are excellent. While two decades ago, even locally limited cancers of the kidney were cured by radical nephrectomy, treatment today mostly consists of local treatment for locally confined cancers. Guidelines today recommend local surgical excision (open or minimally-invasive) or - in selected cases - topical energy application (radio-frequency ablation, cryoablation)....
Source: Aktuelle Urologie - July 28, 2020 Category: Urology & Nephrology Authors: Eich C, Giessing M Tags: Aktuelle Urol Source Type: research

[Clinical management of high-risk non-muscle-invasive bladder cancer during BCG shortage: what are the options, what are the risks?]
Abstract High-risk NMIBC is challenging since, although not being muscle-invasive, it is characterised by a high propensity for progression. It is important to determine the prognostic group, which should be done by means of nomograms. Following thorough transurethral resection, adjuvant therapy with BCG is a standard treatment, but BCG is partly unavailable at present due to shortage. Hyperthermic chemotherapy has also been studied, but its broad use is not yet justified based on the data currently available, which also holds true for checkpoint blockade inhibition. Therefore, given the high propensity for progre...
Source: Aktuelle Urologie - July 15, 2020 Category: Urology & Nephrology Authors: Burger M Tags: Aktuelle Urol Source Type: research

[Bladder hernia: report of a case series and review of the literature].
PMID: 32604428 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 30, 2020 Category: Urology & Nephrology Authors: Trenti E, Palermo S, Huqi D, Ladurner C, Krause P, Pycha A, Comploj E Tags: Aktuelle Urol Source Type: research

[Pre-, intra- and postoperative predictors of functional outcome following radical prostatectomy].
Abstract Maintaining continence and erectile function is crucial for quality of life after radical prostatectomy. This review provides an overview of available evidence concerning preoperative risk stratification as well as intra- and postoperative factors determining functional outcomes after radical prostatectomy.Current data indicate that patient factors including age, baseline erectile function, prostate size, body-mass index and comorbidity status are valid predictors of functional outcome after prostatectomy. While surgical methods do not seem to have any influence, intraoperative procedures like nerve-spari...
Source: Aktuelle Urologie - June 25, 2020 Category: Urology & Nephrology Authors: Krausewitz P, Ritter M Tags: Aktuelle Urol Source Type: research

[The impact of radical cystectomy on health-related quality of life and potential for optimisation].
Abstract Radical cystectomy may have a major impact on the lives of affected patients. Older patients often have a reduced life expectancy after radical cystectomy. Therefore, aspects of health-related quality of life (HRQOL) have to be balanced against a solely tumour-directed therapy. In this narrative review, factors influencing the HRQOL of affected patients were identified and discussed by selective literature search.Besides strategies to minimise perioperative morbidity, these include a patient-oriented and individualised treatment plan taking into account factors such as age, comorbidities, choice of urinar...
Source: Aktuelle Urologie - June 24, 2020 Category: Urology & Nephrology Authors: Rudolph J, Martini T, Wezel F Tags: Aktuelle Urol Source Type: research

[Bladder hernia: report of a case series and review of the literature].
We report a case series of five patients with the rare pathology of bladder hernia treated in our department in the past 20 years. PMID: 32557520 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 18, 2020 Category: Urology & Nephrology Authors: Trenti E, Palermo S, Huqi D, Ladurner C, Krause P, Pycha A, Comploj E Tags: Aktuelle Urol Source Type: research

[Prostate cancer: surgical complications].
Abstract Radical prostatectomy (RP), performed as an open, laparoscopic or robotic procedure, remains the "gold standard" for patients with localised prostate cancer who can be cured with surgery and have a life expectancy of at least 10 years. Today, RP is also used as a first-line treatment for locally advanced prostate cancer, possibly in a multimodal setting with adjuvant radiation/hormonal therapy. The increasing experience of surgeons, better knowledge of anatomy and refinements of surgical techniques have greatly improved oncological and functional outcomes. In our article we would like to give an...
Source: Aktuelle Urologie - June 17, 2020 Category: Urology & Nephrology Authors: Haidl F, Al-Monajjed R Tags: Aktuelle Urol Source Type: research

[Retroperitoneal lymph node dissection in testicular germ cell tumours: indications, complications and special cases].
PMID: 32557448 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 17, 2020 Category: Urology & Nephrology Authors: John P, Albers P, Hiester A, Heidenreich A Tags: Aktuelle Urol Source Type: research

[Sequential therapy for asymptomatic or mildly symptomatic metastatic castration-resistant prostate cancer].
Abstract Abiraterone acetate (in combination with prednisone/prednisolone (abiraterone/P)), enzalutamide or docetaxel may all be used for the first-line treatment of asymptomatic or mildly symptomatic mCRPC. As treatment with docetaxel can result in the emergence of considerable adverse events, the less toxic substances abiraterone/P and enzalutamide are important alternatives. Apart from the safety and clinical effectiveness of these therapies, their optimal sequencing can play a significant role when choosing a mCRPC first-line therapy. Until recently, only retrospective trials were conducted, investigating the ...
Source: Aktuelle Urologie - June 16, 2020 Category: Urology & Nephrology Authors: Miller K Tags: Aktuelle Urol Source Type: research

[Potential for improvement by new resection and imaging techniques in TUR-B].
Abstract Transurethral resection of bladder tumors (TURB) is the cornerstone in urological care of bladder cancer patients. Since the introduction of resectoscopes almost 100 years ago, little has changed in the basic resection technique. The further dissemination of the en-bloc resection (ERBT), which in contrast to fragmented removal preserves the tumor's integrity, might re-adjust the surgical landscape. Benefits attributed to ERBT are better histopathological judgment and higher detrusor muscle rate. In addition, trends for a lower rate of so-called "in-field" recurrences as well as a reduced complic...
Source: Aktuelle Urologie - June 10, 2020 Category: Urology & Nephrology Authors: Hennig MJP, Kramer MW Tags: Aktuelle Urol Source Type: research

Editorial.
PMID: 32485762 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Authors: Roth SS Tags: Aktuelle Urol Source Type: research

[Local therapy for metastasized tumors - paradigm change?]
PMID: 32485763 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Authors: Miller K Tags: Aktuelle Urol Source Type: research

Nierenzysten: Pr ävalenz und klinischer Verlauf bei Kindern.
Nierenzysten: Prävalenz und klinischer Verlauf bei Kindern. Aktuelle Urol. 2020 Jun;51(3):228-229 Authors: PMID: 32485764 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Enuresis: Bedeutung von Entleerungsvolumen und erwarteter Blasenkapazit ät.
Enuresis: Bedeutung von Entleerungsvolumen und erwarteter Blasenkapazität. Aktuelle Urol. 2020 Jun;51(3):229-231 Authors: PMID: 32485765 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Vesikostomie nach Mitrofanoff – welches Gewebe ist am geeignetsten?
Vesikostomie nach Mitrofanoff – welches Gewebe ist am geeignetsten? Aktuelle Urol. 2020 Jun;51(3):231-232 Authors: PMID: 32485766 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Androgenentzug: Kardiovaskul äre Komplikationen unter GnRH-Antagonisten seltener.
Androgenentzug: Kardiovaskuläre Komplikationen unter GnRH-Antagonisten seltener. Aktuelle Urol. 2020 Jun;51(3):232-234 Authors: PMID: 32485767 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

Antibiotikaprophylaxe vor TURP: Geht es auch ohne?
Authors: PMID: 32485768 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Tags: Aktuelle Urol Source Type: research

[A Phase 2, Randomized, Open-Label Study of Nivolumab Combined with Ipilimumab Versus Sunitinib Monotherapy in Subjects with Previously Untreated and Advanced (unresectable or metastatic) non-clear Cell Renal Cell Carcinoma - SUNNIFORECAST AN 41/16 der AUO].
PMID: 32485769 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Authors: Rexer H, Bergmann L, Steiner T Tags: Aktuelle Urol Source Type: research

Praktische intraoperative H ämostase bei offener Adenomenukleation der Prostata.
Praktische intraoperative Hämostase bei offener Adenomenukleation der Prostata. Aktuelle Urol. 2020 Jun;51(3):239-240 Authors: Fallahi M, Horstmann J, Ting O, Roth S, Brandt AS PMID: 32485770 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Authors: Fallahi M, Horstmann J, Ting O, Roth S, Brandt AS Tags: Aktuelle Urol Source Type: research

[An unusual cause for difficulties with the Insertion of a Foley catheter].
PMID: 32485771 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Authors: Wiedemann A Tags: Aktuelle Urol Source Type: research

Leserbrief zum Beitrag: Ist Hormontherapie bei Hodenhochstand noch zeitgem äß? Aktuelle Urologie 2020; 51: 183 – 185.
Leserbrief zum Beitrag: Ist Hormontherapie bei Hodenhochstand noch zeitgemäß? Aktuelle Urologie 2020; 51: 183 – 185. Aktuelle Urol. 2020 Jun;51(3):244-247 Authors: Hadziselimovic F, Höcht B PMID: 32485772 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Authors: Hadziselimovic F, Höcht B Tags: Aktuelle Urol Source Type: research

Antwort auf den Leserbrief.
r A PMID: 32485773 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Authors: Schröder A Tags: Aktuelle Urol Source Type: research

Laparoskopische transperitoneale Nephrektomie und Nierenzystenresektion – transperitoneale laparoskopische Nephrektomie und Tumornephrektomie.
Laparoskopische transperitoneale Nephrektomie und Nierenzystenresektion – transperitoneale laparoskopische Nephrektomie und Tumornephrektomie. Aktuelle Urol. 2020 Jun;51(3):299-308 Authors: Porres D, Pfister D, Heidenreich A PMID: 32485774 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - June 1, 2020 Category: Urology & Nephrology Authors: Porres D, Pfister D, Heidenreich A Tags: Aktuelle Urol Source Type: research

[Bladder cancer - complications related to urinary diversion].
Abstract Even today, radical cystectomy with urinary diversion is one of the most complicated procedures in uro-oncology. Particularly in the long-term course, but also perioperatively, problems caused by urinary diversion play a significant role.Perioperatively, gastrointestinal problems such as an ileus, but also infections and early complications of the different anastomoses are most important. While ileus and perioperative infections can usually be treated conservatively, failure of the intestinal or ureteroileal anastomoses require regular surgical revisions.In the long-term follow-up, scarring can lead to ch...
Source: Aktuelle Urologie - May 27, 2020 Category: Urology & Nephrology Authors: Pfister D, Niegisch G Tags: Aktuelle Urol Source Type: research

Die pr äoperative Anwendung von Dutasterid hat keine Auswirkung auf intraoperative Blutungen bei transvesikaler offener einfacher Prostatektomie zur Behandlung der benignen Prostatahyperplasie.
CONCLUSION: We were not able to find an advantage of pre-operative dutasteride use in terms of perioperative bleeding in open simple prostatectomy performed for benign prostatic hyperplasia. PMID: 32450574 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - May 19, 2020 Category: Urology & Nephrology Authors: Guner E, Ugur R Tags: Aktuelle Urol Source Type: research

[Treatment of the primary tumour in oligometastatic prostate cancer].
Abstract In the treatment of metastatic prostate cancer, significant improvements have recently been made. In addition to androgen deprivation, various options are available, such as anti-androgen receptor therapies with abiraterone and enzalutamide and taxane-based chemotherapy. It is still being discussed whether oligometastatic patients should only be treated systemically, or whether they benefit from additional local therapy for the primary tumour. Until mid-2018, there was no evidence-based recommendation to perform local prostate irradiation in newly diagnosed prostate cancer with distant metastases. At best...
Source: Aktuelle Urologie - May 5, 2020 Category: Urology & Nephrology Authors: Bottke D, Wiegel T Tags: Aktuelle Urol Source Type: research

[Surgical treatment of pulmonary metastases in metastatic renal cell carcinoma].
Abstract Between 20 and 30 % of patients diagnosed with renal cell carcinoma suffer from metastatic disease by the time of diagnosis and a further 20 - 30 % develop metachronous metastases after initial treatment with curative intent. The therapeutic landscape of metastatic renal cell carcinoma seems be changing rapidly, with new systemic therapies or combination therapies available and established concepts being questioned because of long-awaited data. Apart from systemic therapy, metastases can be treated by surgical resection. As the most common site of metastases in renal cell carcinoma, the lung plays...
Source: Aktuelle Urologie - April 23, 2020 Category: Urology & Nephrology Authors: Gilbert N Tags: Aktuelle Urol Source Type: research

[Surgery only? Multimodal treatment for urothelial carcinoma of the bladder].
This article summarises the current literature on multimodal treatment options in a neoadjuvant and adjuvant setting and analyses alternative potentially curative treatments. The article also summarises the initial results using checkpoint inhibitors in a multimodal treatment setting. PMID: 32289833 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - April 14, 2020 Category: Urology & Nephrology Authors: Schuettfort V, Shariat SF, Rink M Tags: Aktuelle Urol Source Type: research

Der Nutzen des De-Ritis-Quotienten zur Absch ätzung der Prognose bei Hodenkrebs.
Der Nutzen des De-Ritis-Quotienten zur Abschätzung der Prognose bei Hodenkrebs. Aktuelle Urol. 2020 Apr 08;: Authors: Guner E, Seker KG, Arikan Y, Huseynov C, Sam E, Ozdal OL PMID: 32268435 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - April 8, 2020 Category: Urology & Nephrology Authors: Guner E, Seker KG, Arikan Y, Huseynov C, Sam E, Ozdal OL Tags: Aktuelle Urol Source Type: research

[Early- vs. late-onset treatment using abiraterone acetate plus prednisone in chemo-na ïve, asymptomatic or mildly symptomatic patients with metastatic CRPC after androgen deprivation therapy].
CONCLUSIONS:  In contrast to the new definition of castration resistance, AA + P was still more frequently used in daily clinical practice during the study observation period in patients treated with antiandrogens of the first generation after occurrence of castration resistance. Nevertheless, AA + P therapy appears to be effective and well tolerated during clinical routine in mCRPC patients. A comparison of the study results with earlier 'real-world' studies, however, has to take limiting factors into account. The observed difference in median overall survival might be explained by the imbalance of baseline c...
Source: Aktuelle Urologie - April 8, 2020 Category: Urology & Nephrology Authors: Merseburger AS, Rüssel C, Belz H, Spiegelhalder P, Feyerabend S, Tran N, Kruetzfeldt K, Baurecht W, Bögemann M Tags: Aktuelle Urol Source Type: research

[Stereotactic body radiotherapy (SBRT) for the treatment of bone metastases in oligometastasised prostate cancer].
CONCLUSION:  SBRT of bone metastases in oligometastatic prostate carcinoma patients is an effective and well tolerated therapy and can help to achieve high local control in the area of the metastases as well as delay the start or the escalation of systemic therapy. Nevertheless, the high rate of progression of distant metastases shows how important correct patient selection is and that combination with aHT may be necessary. PMID: 32268437 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - April 8, 2020 Category: Urology & Nephrology Authors: Sage EK, Vogel MME, Dewes S, Devecka M, Eiber M, Gschwend JE, Combs SE, Schiller K Tags: Aktuelle Urol Source Type: research

[Sigmoid colon conduit volvulus: an extremely rare complication of a sigmoid colon conduit].
We report the case of an 84-year-old man with the rare diagnosis of a volvulus of an incontinent sigmoid colon urinary conduit after radical cystoprostatectomy due to urinary bladder cancer. To the best of our knowledge, this is the first case in literature of a volvulus of a sigmoid colon conduit. PMID: 32259867 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - April 7, 2020 Category: Urology & Nephrology Authors: Trenti E, Palermo S, Pycha A, Comploj E Tags: Aktuelle Urol Source Type: research

[Systemic therapy for metastatic urothelial carcinoma - Current status and what comes after checkpoint inhibitors?]
Abstract The increasing knowledge of the influence of the immune system on tumour development and progression has fundamentally changed our understanding of tumour biology in recent years. While the available treatment options for patients with metastatic urothelial carcinoma of the urinary bladder have hardly improved over decades, the advent of immune checkpoint inhibitors has caused major changes in the corresponding treatment landscape.Although cisplatin-based combination therapies remain the main element, additional effective treatment options now exist with the PD-(L)-1 inhibitors atezolizumab, pembrolizumab...
Source: Aktuelle Urologie - April 7, 2020 Category: Urology & Nephrology Authors: Grunewald CM, Hiester A, Niegisch G Tags: Aktuelle Urol Source Type: research

Editorial.
PMID: 32208502 [PubMed - in process] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - March 27, 2020 Category: Urology & Nephrology Authors: Miller KS Tags: Aktuelle Urol Source Type: research

[Controversies in pediatric and adolescent urology].
PMID: 32208503 [PubMed - in process] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - March 27, 2020 Category: Urology & Nephrology Authors: Stein R Tags: Aktuelle Urol Source Type: research

Handy-Handbuch – Ein Bild sagt mehr als 1000 Worte.
Handy-Handbuch – Ein Bild sagt mehr als 1000 Worte. Aktuelle Urol. 2020 Apr;51(2):104 Authors: Klepper L, Wiedemann A PMID: 32208510 [PubMed] (Source: Aktuelle Urologie)
Source: Aktuelle Urologie - March 27, 2020 Category: Urology & Nephrology Authors: Klepper L, Wiedemann A Tags: Aktuelle Urol Source Type: research