R1617Q epilepsy mutation slows NaV 1.6 sodium channel inactivation and increases the persistent current and neuronal firing.
This article is protected by copyright. All rights reserved. PMID: 33442870 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 14, 2021 Category: Physiology Authors: Poulin H, Chahine M Tags: J Physiol Source Type: research

Pushing the needle forward on the relationship between autoimmunity and autonomic dysfunction.
PMID: 33442880 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 14, 2021 Category: Physiology Authors: Stute NL, Koopmans PJ Tags: J Physiol Source Type: research

Influence of iron manipulation on hypoxic pulmonary vasoconstriction and pulmonary reactivity during ascent and acclimatization to 5050 m.
This article is protected by copyright. All rights reserved. PMID: 33442904 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 14, 2021 Category: Physiology Authors: Willie CK, Patrician A, Hoiland RL, Williams AM, Gasho C, Subedi P, Anholm J, Drane A, Tymko MM, Nowak-Flück D, Plato S, McBride E, Varoli G, Binsted G, Eller LK, Reimer RA, MacLeod DB, Stembridge M, Ainslie PN Tags: J Physiol Source Type: research

The enigma of cerebral blood flow and cognition.
PMID: 33442911 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 14, 2021 Category: Physiology Authors: Ibrahim NA, Badour MI, Stone RM, Shepley BR Tags: J Physiol Source Type: research

B ötzinger inhibitory neurons and the control of active expiration.
Bötzinger inhibitory neurons and the control of active expiration. J Physiol. 2021 Jan 14;: Authors: Takakura AC PMID: 33442917 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 14, 2021 Category: Physiology Authors: Takakura AC Tags: J Physiol Source Type: research

Impact of pre-exercise feeding status on metabolic adaptations to endurance-type exercise training.
This article is protected by copyright. All rights reserved. PMID: 33428210 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 11, 2021 Category: Physiology Authors: Edinburgh RM, Koumanov F, Gonzalez JT Tags: J Physiol Source Type: research

Mitochondria: Powerhouses of Presynaptic Plasticity.
PMID: 33428213 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 11, 2021 Category: Physiology Authors: Subramanian S, Jonas EA Tags: J Physiol Source Type: research

Infra-slow modulation of fast beta/gamma oscillations in the mouse visual system.
Abstract KEY POINTS: Neurophysiological activity in the subcortical visual system fluctuates in both infra-slow and fast oscillatory ranges, however the level of co-occurrence and potential functional interaction of these rhythms is unknown. Analyzing dark-adapted spontaneous activity in the mouse subcortical visual system, we find that these two types of oscillation interact uniquely through a population of neurons expressing both rhythms. Genetic ablation of rod/cone signaling potentiates infra-slow and abolishes fast beta/gamma oscillations while genetic ablation of melanopsin substantially diminishes the inter...
Source: The Journal of Physiology - January 11, 2021 Category: Physiology Authors: Orlowska-Feuer P, Allen AE, Brown TM, Szkudlarek HJ, Lucas RJ, Storchi R Tags: J Physiol Source Type: research

Inhaled nitric oxide improves ventilatory efficiency and exercise capacity in patients with mild COPD: A randomized-control crossover trial.
Abstract KEY POINTS: Patients with mild chronic obstructive pulmonary disease (COPD) have an elevated ventilatory equivalent to CO2 production (V̇E /V̇CO2 ) during exercise, secondary to increased dead space ventilation. The reason for the increased dead space is unclear, however, pulmonary microvascular dysfunction and the corresponding capillary hypoperfusion is a potential mechanism. Despite emerging evidence that mild COPD is associated with pulmonary microvascular dysfunction, limited research has focused on experimentally modulating the pulmonary microvasculature during exercise in mild COPD. The current s...
Source: The Journal of Physiology - January 11, 2021 Category: Physiology Authors: Phillips DB, Brotto AR, Ross BA, Bryan TL, Wong EYL, Meah VL, Fuhr DP, van Diepen S, Stickland MK Tags: J Physiol Source Type: research

Arterial carbon dioxide and bicarbonate rather than pH regulate cerebral blood flow in the setting of acute experimental metabolic alkalosis.
Abstract KEY POINTS: We investigated the influence of arterial PCO2 (PaCO2 ) with and without acutely elevated arterial pH and bicarbonate ([HCO3 - ]) on cerebral blood flow (CBF) regulation in the internal carotid artery and vertebral artery. We assessed stepwise iso-oxic alterations in PaCO2 (i.e., cerebrovascular CO2 reactivity) prior to and following intravenous sodium bicarbonate infusion (NaHCO3 - ) to acutely elevate arterial pH and [HCO3 - ]. Total CBF was unchanged irrespective of a higher arterial pH at each matched stage of PaCO2 , indicating that CBF is acutely regulated by PaCO2 rather than arterial p...
Source: The Journal of Physiology - January 6, 2021 Category: Physiology Authors: Caldwell HG, Howe CA, Chalifoux CJ, Hoiland RL, Carr JMJR, Brown CV, Patrician A, Tremblay JC, Panerai RB, Robinson TG, Minhas JS, Ainslie PN Tags: J Physiol Source Type: research

Role of pattern recognition receptors and the microbiota in neurological disorders.
This article is protected by copyright. All rights reserved. PMID: 33404072 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 6, 2021 Category: Physiology Authors: Keogh CE, Rude KM, Gareau MG Tags: J Physiol Source Type: research

Unpreserved muscle function in heart failure with preserved ejection fraction; diffusion limitations defused.
PMID: 33404101 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - January 6, 2021 Category: Physiology Authors: Hendrickse P, Degens H Tags: J Physiol Source Type: research

Pressure-sensing Piezo1: the eyes have it.
PMID: 33372279 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 28, 2020 Category: Physiology Authors: Swain SM, Liddle RA Tags: J Physiol Source Type: research

The influence of aerobic exercise on mitochondrial quality control in skeletal muscle.
This article is protected by copyright. All rights reserved. PMID: 33369731 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 28, 2020 Category: Physiology Authors: Philp AM, Saner NJ, Lazarou M, Ganley IG, Philp A Tags: J Physiol Source Type: research

The effects of maternal position, in late gestation pregnancy, on placental blood flow and oxygenation: An MRI study.
Abstract KEY POINTS: Maternal supine sleep position in late pregnancy is associated with an increased risk of stillbirth. Maternal supine position in late pregnancy reduces maternal cardiac output and uterine blood flow. Using MRI, this study shows that compared to the left lateral position, maternal supine position in late pregnancy is associated with reduced uteroplacental blood flow, oxygen transfer across the placenta with an average 6.2% reduction in oxygen delivery to the fetus and an average 11% reduction in fetal umbilical venous blood flow. ABSTRACT: Maternal sleep position in late gestation is assoc...
Source: The Journal of Physiology - December 28, 2020 Category: Physiology Authors: Couper S, Clark A, Thompson JMD, Flouri D, Aughwane R, David AL, Melbourne A, Mirjalili A, Stone PR Tags: J Physiol Source Type: research

Maximum axonal following frequency separates classes of cutaneous unmyelinated nociceptors in the pig.
This article is protected by copyright. All rights reserved. PMID: 33369733 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 28, 2020 Category: Physiology Authors: Werland F, Hirth M, Rukwied R, Ringkamp M, Turnquist B, Jorum E, Namer B, Schmelz M, Obreja O Tags: J Physiol Source Type: research

Abnormal cerebellar function and tremor in a mouse model for non-manifesting DYT6.
This article is protected by copyright. All rights reserved. PMID: 33369735 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 28, 2020 Category: Physiology Authors: van der Heijden ME, Kizek DJ, Perez R, Ruff EK, Ehrlich ME, Sillitoe RV Tags: J Physiol Source Type: research

Post-exercise intramuscular O2 supply is tightly coupled with a higher proximal-to-distal ATP synthesis rate in human tibialis anterior.
Abstract KEY POINTS: The post-exercise recovery of phosphocreatine, a measure of the oxidative capacity of muscles, as assessed by 31 P MR spectroscopy, shows a striking increase from distal to proximal along the human tibialis anterior muscle. To investigate why this muscle exhibits a greater oxidative capacity proximally, we tested whether the spatial variation in phosphocreatine recovery rate is related to oxygen supply, muscle fiber type or type of exercise. We revealed that oxygen supply also increases from distal to proximal along the tibialis anterior, and that it strongly correlated with phosphocreatine re...
Source: The Journal of Physiology - December 28, 2020 Category: Physiology Authors: Heskamp L, Lebbink F, van Uden MJ, Maas MC, Claassen JAHR, Froeling M, Kemp GJ, Boss A, Heerschap A Tags: J Physiol Source Type: research

ATP-sensitive K+ channels control the spontaneous firing of a glycinergic interneuron in the auditory brainstem.
This article is protected by copyright. All rights reserved. PMID: 33369743 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 28, 2020 Category: Physiology Authors: Strazza PS, de Siqueira DVF, Leão RM Tags: J Physiol Source Type: research

Sexually dimorphic response of colorectal motility to noxious stimuli in the colorectum in rats.
This study showed a remarkable sex difference in responses of colorectal motility to noxious stimuli in the colorectum in rats: colorectal motility was enhanced in response to intracolonic administration of a noxious stimulant, capsaicin, in male rats but not in female rats. The difference in descending neurons from the brain to spinal cord operating after noxious stimulation would be responsible for the sex difference. In male rats, serotoninergic and dopaminergic neurons are dominantly activated, both of which activate the spinal defaecation centre. In female rats, GABAergic neurons in addition to serotoninergic neurons ...
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Horii K, Ehara Y, Shiina T, Naitou K, Nakamori H, Horii Y, Shimaoka H, Saito S, Shimizu Y Tags: J Physiol Source Type: research

Sympathetic reactivity and inflammation: another joint problem in rheumatoid arthritis?
PMID: 33347607 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Fisher JP Tags: J Physiol Source Type: research

Can aerobic exercise alleviate the compound detrimental effects of age and western diet on vascular function?
PMID: 33347608 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Gomez DH, Aldokhayyil M Tags: J Physiol Source Type: research

No matter the type, when it comes to recovery all fibers are similar.
PMID: 33347609 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Lovell AJ Tags: J Physiol Source Type: research

"Silent hypoxaemia in COVID-19 patients".
This article is protected by copyright. All rights reserved. PMID: 33347610 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Simonson TS, Baker TL, Banzett RB, Bishop T, Dempsey JA, Feldman JL, Guyenet PG, Hodson EJ, Mitchell GS, Moya EA, Nokes BT, Orr JE, Owens RL, Poulin M, Rawling JM, Schmickl CN, Watters JJ, Younes M, Malhotra A Tags: J Physiol Source Type: research

Revisiting the warburg effect: historical dogma versus current understanding.
This article is protected by copyright. All rights reserved. PMID: 33347611 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Vaupel P, Multhoff G Tags: J Physiol Source Type: research

Abnormal skeletal muscle blood flow, contractile mechanics, and fibre morphology in a rat model of obese-HFpEF.
This study used a cardiometabolic obese HFpEF rat model to comprehensively phenotype skeletal muscle mechanics, blood flow, microvasculature, and fibre atrophy. Lean (n = 8) and obese-HFpEF (n = 8) ZSF1 rats were compared. Skeletal muscles (soleus and diaphragm) were assessed for in vitro contractility (isometric and isotonic properties) alongside indices of fibre-type cross-sectional area, myosin isoform, and capillarity, and estimated muscle PO2 . In situ extensor digitorum longus (EDL) contractility and femoral blood flow were assessed. HFpEF soleus demonstrated lower absolute maximal force by 22%, fibre atrophy by 24%,...
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Espino-Gonzalez E, Tickle PG, Benson AP, Kissane RWP, Askew GN, Egginton S, Bowen TS Tags: J Physiol Source Type: research

TSPAN-7 as a key regulator of glucose-stimulated Ca2+ influx and insulin secretion.
PMID: 33347614 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Helassa N Tags: J Physiol Source Type: research

The reliance on α-adrenergic receptor stimuli for blood pressure regulation in the chronically hypoxaemic fetus is not dependent on post-ganglionic activation.
This article is protected by copyright. All rights reserved. PMID: 33347615 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Darby JRT, Varcoe TJ, Holman SL, McMillen IC, Morrison JL Tags: J Physiol Source Type: research

Diaphragm fatigue: similarities and differences between sexes.
PMID: 33347624 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: O'Halloran KD Tags: J Physiol Source Type: research

Physiological roles of heteromerization: focus on the two-pore domain potassium channels.
This article is protected by copyright. All rights reserved. PMID: 33347640 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Khoubza L, Chatelain FC, Feliciangeli S, Lesage F, Bichet D Tags: J Physiol Source Type: research

Contribution of retrotrapezoid nucleus neurons to CO2 -amplified cardiorespiratory activity in spontaneously hypertensive rats.
This study demonstrates that CO2 -induced both respiratory and cardiovascular responses are augmented in spontaneously hypertensive rats (SHRs). Genetic ablation of the retrotrapezoid nucleus (RTN) neurons depresses enhanced hypercapnic ventilatory response and eliminates CO2 -stimulated increase in arterial pressure and heart rate in SHRs. SHRs have high protein level of pH-sensitive channels in the RTN, including TASK-2 channel, Kv12.1 channel and acid-sensing ion channel 3. The inhibition of putative TASK-2 channel activity by clofilium diminishes amplified hypercapnic ventilatory and cardiovascular responses, and reduc...
Source: The Journal of Physiology - December 21, 2020 Category: Physiology Authors: Tian Y, Geng D, Wang Y, Shi L, Yu H, He W, Zhu Y, Jun S, Fu C, Wang X, Zhang X, Yuan F, Wang S Tags: J Physiol Source Type: research

Placental mitochondria central to gestational diabetes pathogenesis?
PMID: 33337541 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 18, 2020 Category: Physiology Authors: Sferruzzi-Perri AN Tags: J Physiol Source Type: research

Dose-dependent sensorimotor impairment in human ocular tracking after acute low-dose alcohol administration.
Abstract KEY POINTS: Oculomotor behaviours are commonly used to evaluate sensorimotor disruption due to ethanol (EtOH). The current study demonstrates the dose-dependent impairment in oculomotor and ocular behaviours across a range of ultra-low BACs (
Source: The Journal of Physiology - December 17, 2020 Category: Physiology Authors: Tyson TL, Feick NH, Cravalho PF, Flynn-Evans EE, Stone LS Tags: J Physiol Source Type: research

Want to win a bowling game? Beware of even one glass of alcohol!
vre P PMID: 33332617 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 17, 2020 Category: Physiology Authors: Lefèvre P Tags: J Physiol Source Type: research

The somatosensory cortical activity in individuals with cerebral palsy displays an aberrant developmental trajectory.
This article is protected by copyright. All rights reserved. PMID: 33296078 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 9, 2020 Category: Physiology Authors: Trevarrow MP, Kleinsmith J, Taylor BK, Wilson TW, Kurz MJ Tags: J Physiol Source Type: research

Increased intestinal phosphate absorption, an often-overlooked effect of vitamin D.
PMID: 33296085 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 9, 2020 Category: Physiology Authors: Alexander RT Tags: J Physiol Source Type: research

Zona incerta neurons projecting to the ventral tegmental area promote action initiation towards feeding.
This article is protected by copyright. All rights reserved. PMID: 33296086 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 9, 2020 Category: Physiology Authors: de Git KCG, Hazelhoff EM, Nota MHC, Schele E, Luijendijk MCM, Dickson SL, van der Plasse G, Adan RAH Tags: J Physiol Source Type: research

S100 β-mediated astroglial control of firing and input processing in layer 5 pyramidal neurons of the mouse visual cortex.
This article is protected by copyright. All rights reserved. PMID: 33289081 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 2, 2020 Category: Physiology Authors: Ryczko D, Hanini-Daoud M, Condamine S, Bréant BJB, Fougère M, Araya R, Kolta A Tags: J Physiol Source Type: research

Plasma volume contraction at altitude: where does the plasma go?
PMID: 33289082 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 2, 2020 Category: Physiology Authors: Robach P, Lundby C Tags: J Physiol Source Type: research

Chronic aerobic exercise: targeting two birds with one stone.
PMID: 33289103 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 2, 2020 Category: Physiology Authors: Islam MT, Hall SA, Lesniewski LA Tags: J Physiol Source Type: research

The post-inspiratory complex (PiCo), what is the evidence?
n S PMID: 33258194 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 1, 2020 Category: Physiology Authors: Hülsmann S Tags: J Physiol Source Type: research

The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor (VDR) in vivo.
Conclusion Taken together, these data indicate a fundamental regulatory role of the VDR in the regulation of myogenesis and muscle mass; whereby it acts to maintain muscle mitochondrial function and limit autophagy. Joseph Bass completed his PhD in Medicine and Health in 2017 at The University of Nottingham, where he is currently a Research Fellow. Joe is interested in examining the mechanistic regulation of musculoskeletal health, particularly factors impacting muscle atrophy susceptibility. This article is protected by copyright. All rights reserved. PMID: 33258480 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - December 1, 2020 Category: Physiology Authors: Bass JJ, Kazi AA, Deane CS, Nakhuda A, Ashcroft SP, Brook MS, Wilkinson DJ, Phillips BE, Philp A, Tarum J, Kadi F, Andersen D, Garcia AM, Smith K, Gallagher IJ, Szewczyk NJ, Cleasby ME, Atherton PJ Tags: J Physiol Source Type: research

Nicotinic receptor activation induces NMDA-receptor independent long-term potentiation of glutamatergic signalling in hippocampal oriens interneurons.
This study adds nicotinic receptors to the list of sources of Ca2+ that induce NMDA receptor-independent LTP in hippocampal oriens interneurons. ABSTRACT: Many interneurons located in stratum oriens of the rodent hippocampus exhibit a form of long-term potentiation (LTP) of glutamatergic transmission that does not depend on NMDA receptors for its induction but instead requires Ca2+ -permeable AMPA receptors and group I metabotropic glutamate receptors. A role for cholinergic signalling has also been reported. However, electrical stimulation of presynaptic axons, conventionally used to evoke synaptic responses, does no...
Source: The Journal of Physiology - November 29, 2020 Category: Physiology Authors: Nicholson E, Kullmann DM Tags: J Physiol Source Type: research

Passive stiffness of fibrotic skeletal muscle in mdx mice relates to collagen architecture.
This article is protected by copyright. All rights reserved. PMID: 33247944 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - November 28, 2020 Category: Physiology Authors: Brashear SE, Wohlgemuth RP, Gonzalez G, Smith LR Tags: J Physiol Source Type: research

High-glucose mixed meals impair microvascular function: the attenuating effect of exercise.
PMID: 33241858 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - November 26, 2020 Category: Physiology Authors: Alvares TS Tags: J Physiol Source Type: research

Spaceflight not an eye-popping experience for astronauts.
PMID: 33242219 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - November 26, 2020 Category: Physiology Authors: Hughson RL, Irving E Tags: J Physiol Source Type: research

IRBIT activates NBCe1-B by releasing the auto-inhibition module from the transmembrane domain.
This article is protected by copyright. All rights reserved. PMID: 33237573 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - November 25, 2020 Category: Physiology Authors: Su P, Wu H, Wang M, Cai L, Liu Y, Chen LM Tags: J Physiol Source Type: research

The human preference for symmetric walking often disappears when one leg is constrained.
Abstract KEY POINTS: We hypothesized that minimization of metabolic power could drive people to walk asymmetrically when one leg is constrained We studied healthy young adults and independently constrained one or both step lengths to be markedly shorter or longer than preferred using visual feedback When one leg was constrained to take a shorter or longer step than preferred, asymmetric walking patterns were less metabolically costly than symmetric walking patterns When one leg was constrained to take a shorter or longer step than preferred and the other leg was allowed to move freely, most participants naturally ...
Source: The Journal of Physiology - November 24, 2020 Category: Physiology Authors: Browne MG, Smock CS, Roemmich RT Tags: J Physiol Source Type: research

Muscling in on neurorehabilitative strategies to counter respiratory motor dysfunction in cervical spinal cord injury.
PMID: 33226628 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - November 23, 2020 Category: Physiology Authors: O'Halloran KD Tags: J Physiol Source Type: research

Physical activity and cancer biology: navigating a pathophysiologic maze and broadening therapeutic imagination.
PMID: 33226633 [PubMed - as supplied by publisher] (Source: The Journal of Physiology)
Source: The Journal of Physiology - November 23, 2020 Category: Physiology Authors: Ugwoke CK, Umek N Tags: J Physiol Source Type: research