Physiological mechanism of acute exercise benefits for human cognition: possible involvement of dopamine release and central command
J Physiol. 2024 Feb 27. doi: 10.1113/JP286234. Online ahead of print.NO ABSTRACTPMID:38412050 | DOI:10.1113/JP286234 (Source: The Journal of Physiology)
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Ryuta Kuwamizu Yujiro Yamada Source Type: research
Right ventricular performance during acute hypoxic exercise
In conclusion, resting and exertional RV functions are preserved in response to acute exposure to hypoxia at an F i O 2 ${F_{{\mathrm{i}}{{\mathrm{O}}_{\mathrm{2}}}}}$ = 0.12 and the associated increase in PA pressures. KEY POINTS: The healthy right ventricle augments contractility, lusitropy and energetics during periods of increased metabolic demand (e.g. exercise) in acute hypoxic conditions. During submaximal exercise, ventricular-arterial coupling decreases but remains within normal limits, ensuring that cardiac output and systemic perfusion are maintained. These data describe right ventricular physiological respo...
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Lindsay M Forbes Todd M Bull Tim Lahm Tyler Sisson Katie O'Gean Justin S Lawley Kendall Hunter Benjamin D Levine Andrew Lovering Robert C Roach Andrew W Subudhi William K Cornwell Source Type: research
Daily blood flow restriction does not preserve muscle mass and strength during 2 weeks of bed rest
J Physiol. 2024 Feb 27. doi: 10.1113/JP286065. Online ahead of print.ABSTRACTWe measured the impact of blood flow restriction on muscle protein synthesis rates, muscle mass and strength during 2 weeks of strict bed rest. Twelve healthy, male adults (age: 24 ± 3 years, body mass index: 23.7 ± 3.1 kg/m2 ) were subjected to 14 days of strict bed rest with unilateral blood flow restriction performed three times daily in three 5 min cycles (200 mmHg). Participants consumed deuterium oxide and we collected blood and saliva samples throughout 2 weeks of bed rest. Before and immediately after bed rest, lean body mass (dual-energ...
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Cas J Fuchs Wesley J H Hermans Jean Nyakayiru Michelle E G Weijzen Joey S J Smeets Thorben Aussieker Joan M Senden Will K H W Wodzig Tim Snijders Lex B Verdijk Luc J C van Loon Source Type: research
Prehab? Rehab? Both? Exploring interventions to alleviate disuse-induced muscle atrophy and anabolic resistance in older adults
J Physiol. 2024 Feb 27. doi: 10.1113/JP286231. Online ahead of print.NO ABSTRACTPMID:38412049 | DOI:10.1113/JP286231 (Source: The Journal of Physiology)
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Nigel L M LeGood XinYue Li Michelle Ha Joshua D R Downer Source Type: research
Physiological mechanism of acute exercise benefits for human cognition: possible involvement of dopamine release and central command
J Physiol. 2024 Feb 27. doi: 10.1113/JP286234. Online ahead of print.NO ABSTRACTPMID:38412050 | DOI:10.1113/JP286234 (Source: The Journal of Physiology)
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Ryuta Kuwamizu Yujiro Yamada Source Type: research
Right ventricular performance during acute hypoxic exercise
In conclusion, resting and exertional RV functions are preserved in response to acute exposure to hypoxia at an F i O 2 ${F_{{\mathrm{i}}{{\mathrm{O}}_{\mathrm{2}}}}}$ = 0.12 and the associated increase in PA pressures. KEY POINTS: The healthy right ventricle augments contractility, lusitropy and energetics during periods of increased metabolic demand (e.g. exercise) in acute hypoxic conditions. During submaximal exercise, ventricular-arterial coupling decreases but remains within normal limits, ensuring that cardiac output and systemic perfusion are maintained. These data describe right ventricular physiological respo...
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Lindsay M Forbes Todd M Bull Tim Lahm Tyler Sisson Katie O'Gean Justin S Lawley Kendall Hunter Benjamin D Levine Andrew Lovering Robert C Roach Andrew W Subudhi William K Cornwell Source Type: research
Daily blood flow restriction does not preserve muscle mass and strength during 2 weeks of bed rest
J Physiol. 2024 Feb 27. doi: 10.1113/JP286065. Online ahead of print.ABSTRACTWe measured the impact of blood flow restriction on muscle protein synthesis rates, muscle mass and strength during 2 weeks of strict bed rest. Twelve healthy, male adults (age: 24 ± 3 years, body mass index: 23.7 ± 3.1 kg/m2 ) were subjected to 14 days of strict bed rest with unilateral blood flow restriction performed three times daily in three 5 min cycles (200 mmHg). Participants consumed deuterium oxide and we collected blood and saliva samples throughout 2 weeks of bed rest. Before and immediately after bed rest, lean body mass (dual-energ...
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Cas J Fuchs Wesley J H Hermans Jean Nyakayiru Michelle E G Weijzen Joey S J Smeets Thorben Aussieker Joan M Senden Will K H W Wodzig Tim Snijders Lex B Verdijk Luc J C van Loon Source Type: research
Prehab? Rehab? Both? Exploring interventions to alleviate disuse-induced muscle atrophy and anabolic resistance in older adults
J Physiol. 2024 Feb 27. doi: 10.1113/JP286231. Online ahead of print.NO ABSTRACTPMID:38412049 | DOI:10.1113/JP286231 (Source: The Journal of Physiology)
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Nigel L M LeGood XinYue Li Michelle Ha Joshua D R Downer Source Type: research
Physiological mechanism of acute exercise benefits for human cognition: possible involvement of dopamine release and central command
J Physiol. 2024 Feb 27. doi: 10.1113/JP286234. Online ahead of print.NO ABSTRACTPMID:38412050 | DOI:10.1113/JP286234 (Source: The Journal of Physiology)
Source: The Journal of Physiology - February 27, 2024 Category: Physiology Authors: Ryuta Kuwamizu Yujiro Yamada Source Type: research
Effects of periodic breathing on sleep at high altitude: a randomized, placebo-controlled, crossover study using inspiratory CO < sub > 2 < /sub >
J Physiol. 2024 Feb 26. doi: 10.1113/JP285397. Online ahead of print.ABSTRACTHypoxia at high altitude facilitates changes in ventilatory control that can lead to nocturnal periodic breathing (nPB). Here, we introduce a placebo-controlled approach to prevent nPB by increasing inspiratory CO2 and used it to assess whether nPB contributes to the adverse effects of hypoxia on sleep architecture. In a randomized, single-blinded, crossover design, 12 men underwent two sojourns (three days/nights each, separated by 4 weeks) in hypobaric hypoxia corresponding to 4000 m altitude, with polysomnography during the first and third nigh...
Source: The Journal of Physiology - February 26, 2024 Category: Physiology Authors: Abubaker Ibrahim Ambra Stefani Matteo Cesari Johanna Roche Hannes Gatterer Evi Holzknecht Rachel Turner Giovanni Vinetti Michael Furian Anna Heidbreder Birgit H ögl Christoph Siebenmann Source Type: research
Conserved mammalian muscle mechanics during eccentric contractions
J Physiol. 2024 Feb 24. doi: 10.1113/JP285549. Online ahead of print.ABSTRACTSkeletal muscle has a broad range of biomechanical functions, including power generation and energy absorption. These roles are underpinned by the force-velocity relationship, which comprises two distinct components: a concentric and an eccentric force-velocity relationship. The concentric component has been extensively studied across a wide range of muscles with different muscle properties. However, to date, little progress has been made in accurately characterising the eccentric force-velocity relationship in mammalian muscle with varying muscle...
Source: The Journal of Physiology - February 24, 2024 Category: Physiology Authors: Roger W P Kissane Graham N Askew Source Type: research
Death by hypoxia: what were they thinking?
J Physiol. 2024 Feb 24. doi: 10.1113/JP286347. Online ahead of print.NO ABSTRACTPMID:38401033 | DOI:10.1113/JP286347 (Source: The Journal of Physiology)
Source: The Journal of Physiology - February 24, 2024 Category: Physiology Authors: Vaughan G Macefield Source Type: research
Conserved mammalian muscle mechanics during eccentric contractions
J Physiol. 2024 Feb 24. doi: 10.1113/JP285549. Online ahead of print.ABSTRACTSkeletal muscle has a broad range of biomechanical functions, including power generation and energy absorption. These roles are underpinned by the force-velocity relationship, which comprises two distinct components: a concentric and an eccentric force-velocity relationship. The concentric component has been extensively studied across a wide range of muscles with different muscle properties. However, to date, little progress has been made in accurately characterising the eccentric force-velocity relationship in mammalian muscle with varying muscle...
Source: The Journal of Physiology - February 24, 2024 Category: Physiology Authors: Roger W P Kissane Graham N Askew Source Type: research
Death by hypoxia: what were they thinking?
J Physiol. 2024 Feb 24. doi: 10.1113/JP286347. Online ahead of print.NO ABSTRACTPMID:38401033 | DOI:10.1113/JP286347 (Source: The Journal of Physiology)
Source: The Journal of Physiology - February 24, 2024 Category: Physiology Authors: Vaughan G Macefield Source Type: research
Conserved mammalian muscle mechanics during eccentric contractions
J Physiol. 2024 Feb 24. doi: 10.1113/JP285549. Online ahead of print.ABSTRACTSkeletal muscle has a broad range of biomechanical functions, including power generation and energy absorption. These roles are underpinned by the force-velocity relationship, which comprises two distinct components: a concentric and an eccentric force-velocity relationship. The concentric component has been extensively studied across a wide range of muscles with different muscle properties. However, to date, little progress has been made in accurately characterising the eccentric force-velocity relationship in mammalian muscle with varying muscle...
Source: The Journal of Physiology - February 24, 2024 Category: Physiology Authors: Roger W P Kissane Graham N Askew Source Type: research
