Eating Disorders & Weight Management Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Relationship between changes in blood glucose, glycosylated hemoglobin [HbA1c], cholesterol, and triglyceride and changes in hepatic enzymes
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):23-28. doi: 10.14715/cmb/2024.70.4.4.ABSTRACTThe main risk factors for non-alcoholic fatty liver disease (NAFLD) are strongly associated with obesity, diabetes, hyperlipidemia, and metabolic syndrome. The best clinical evaluation of the liver is done through studying changes in liver enzymes' activity, especially alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase. Therefore, this study aimed to investigate the relationship between changes in factors such as blood glucose, cholesterol, glycosylated hemoglobin, and triglyceride and changes in hepat...
Source: Cellular and Molecular Biology - April 28, 2024 Category: Molecular Biology Authors: Mahboobeh Talebi Mehrdar Wei Lu Adel Rahanjam Source Type: research

Naive and regulatory B-cell transcription patterns guide the increased risk of papillary thyroid carcinoma in obesity
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):118-126. doi: 10.14715/cmb/2024.70.4.19.ABSTRACTA growing number of studies suggest a positive association between obesity and the high incidence of papillary thyroid cancer (PTC), suggesting that the abnormal levels of adipokines associated with obesity may be a risk factor for these aggressive thyroid cancers, but the underlying regulatory mechanisms are not yet clear. We downloaded bulk RNA sequence data for subcutaneous adipose tissue (SAT) in obesity and healthy population and tumor tissues of PTC from GEO database. Through analysis of Differential Expression Genes (DE...
Source: Cellular and Molecular Biology - April 28, 2024 Category: Molecular Biology Authors: Zihui Yu Ziying Xu Shang Li Ziyan Tian Jing Yuan Source Type: research

Prevalence and determinants of behavioral risk factors for noncommunicable diseases among students aged 13-19 years in Turkey
CONCLUSION: The prevalence of clustering of modifiable risk factors for NCDs was high among students aged 13-19 years in Turkey, and there is a need to mount effective interventions. Risk factors for these diseases are often preventable: Appropriate health interventions before, during, and after pregnancy as well as throughout childhood and adolescence can significantly reduce their prevalence.PMID:38679546 | DOI:10.1016/j.arcped.2024.01.009 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - April 28, 2024 Category: Pediatrics Authors: Hasan H üseyin Çam Fadime Ustuner Top Source Type: research

Fennel seeds extract prevents fructose-induced cardiac dysfunction in a rat model of metabolic syndrome via targeting abdominal obesity, hyperuricemia and NF- κβ inflammatory pathway
CONCLUSION: Findings could suggest FSE as a complementary supplement for preventing MetS and associated cardiac outcomes. However, well controlled clinical studies are still needed.PMID:38678740 | DOI:10.1016/j.tice.2024.102385 (Source: Tissue and Cell)
Source: Tissue and Cell - April 28, 2024 Category: Cytology Authors: Azza Mohamad El-Wakf Mamdouh Rashad El-Sawi Hadeer Mahmoud El-Nigomy Eman Mohamad El-Nashar Norah Saeed Al-Zahrani Nasser G Alqahtani Rashid A Aldahhan Zienab Helmy Eldken Source Type: research

A review on the nexus of autophagy genes from the perspective of polycystic ovary syndrome
Biol Cell. 2024 Apr 28:e202300069. doi: 10.1111/boc.202300069. Online ahead of print.ABSTRACTPolycystic ovary syndrome or PCOS is an endocrine disorder in women of reproductive age. It is a diversified multi factorial disorder and diagnosis is very complicated because of its overlapping symptoms some of which are irregular menstrual cycle, acne in face, excess level of androgen (AE), insulin resistance, obesity, cardiovascular disease, mood disorder and type 2 diabetes (T2DM). PCOS may be caused by hormonal imbalance, genetic and epigenetic vulnerability, hypothalamic and ovarian troubles. PCOS is essentially hyperandrogen...
Source: Biology of the Cell - April 28, 2024 Category: Cytology Authors: Arifa Khatun Taslima Nasrin Md Samim Hassan Mehboob Hoque Muddasarul Hoda Safdar Ali Source Type: research

A shift to a standard diet after exposure to a high-fat, high-sucrose diet from gestation to weaning restores brain metabolism and behavioral flexibility in adult rats
In conclusion, switching from an HFS diet to a balanced diet after weaning would have beneficial effects on behavioral flexibility and brain metabolism, without significant sex differences.PMID:38679144 | DOI:10.1016/j.bbr.2024.115020 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - April 28, 2024 Category: Neurology Authors: Sa úl Sal-Sarria Isabel L ópez-Taboada H éctor González-Pardo N élida M Conejo Source Type: research

A shift to a standard diet after exposure to a high-fat, high-sucrose diet from gestation to weaning restores brain metabolism and behavioral flexibility in adult rats
In conclusion, switching from an HFS diet to a balanced diet after weaning would have beneficial effects on behavioral flexibility and brain metabolism, without significant sex differences.PMID:38679144 | DOI:10.1016/j.bbr.2024.115020 (Source: Brain Research)
Source: Brain Research - April 28, 2024 Category: Neurology Authors: Sa úl Sal-Sarria Isabel L ópez-Taboada H éctor González-Pardo N élida M Conejo Source Type: research

Integrating network pharmacology and experimental validation reveals therapeutic effects of D-mannose on NAFLD through mTOR suppression
In this study, network pharmacology followed by molecular docking analysis was utilized to identify potential targets of mannose against NAFLD, and the leptin receptor-deficient, genetically obese db/db mice was employed as an animal model of NAFLD to validate the regulation of D-mannose on core targets. As a result, 67 targets of mannose are predicted associated with NAFLD, which are surprisingly centered on the mechanistic target of rapamycin (mTOR). Further analyses suggest that mTOR signaling is functionally enriched in potential targets of mannose treating NAFLD, and that mannose putatively binds to mTOR as a core mec...
Source: Biochemical and Biophysical Research communications - April 28, 2024 Category: Biochemistry Authors: Sha Zhang Ying-Feng Gao Kai Zhang Guo-Rong Deng Guang-Xiang He Ping-Ping Gao Yi-Kang Yu Yuan Yuan Shu-Juan Xing Na Zhao Hong Zhang Yong-Chang Di-Wu Yi-Han Liu Bing-Dong Sui Zhe Li Jing Ma Chen-Xi Zheng Source Type: research

Relationship between changes in blood glucose, glycosylated hemoglobin [HbA1c], cholesterol, and triglyceride and changes in hepatic enzymes
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):23-28. doi: 10.14715/cmb/2024.70.4.4.ABSTRACTThe main risk factors for non-alcoholic fatty liver disease (NAFLD) are strongly associated with obesity, diabetes, hyperlipidemia, and metabolic syndrome. The best clinical evaluation of the liver is done through studying changes in liver enzymes' activity, especially alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase. Therefore, this study aimed to investigate the relationship between changes in factors such as blood glucose, cholesterol, glycosylated hemoglobin, and triglyceride and changes in hepat...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Mahboobeh Talebi Mehrdar Wei Lu Adel Rahanjam Source Type: research

Naive and regulatory B-cell transcription patterns guide the increased risk of papillary thyroid carcinoma in obesity
Cell Mol Biol (Noisy-le-grand). 2024 Apr 28;70(4):118-126. doi: 10.14715/cmb/2024.70.4.19.ABSTRACTA growing number of studies suggest a positive association between obesity and the high incidence of papillary thyroid cancer (PTC), suggesting that the abnormal levels of adipokines associated with obesity may be a risk factor for these aggressive thyroid cancers, but the underlying regulatory mechanisms are not yet clear. We downloaded bulk RNA sequence data for subcutaneous adipose tissue (SAT) in obesity and healthy population and tumor tissues of PTC from GEO database. Through analysis of Differential Expression Genes (DE...
Source: Mol Biol Cell - April 28, 2024 Category: Molecular Biology Authors: Zihui Yu Ziying Xu Shang Li Ziyan Tian Jing Yuan Source Type: research