Effect of Virtual Versus In Person Interpreting on Diabetes Outcomes in Non-English Language Preference Patients: A Pilot Study
CONCLUSIONS: Quality medical interpretation contributes to optimal health outcomes in NELP patients with diabetes. Our study suggests that both in person and virtual interpreters can be effective in providing care for NELP patients, especially for chronic disease management in the context of a primary care relationship. It also highlights the importance of pursuing additional qualitative and mixed method studies to better understand the benefits of various interpreter formats across different visit types.PMID:38695439 | DOI:10.1177/21501319241240347 (Source: Primary Care)
Source: Primary Care - May 2, 2024 Category: Primary Care Authors: Marvin So Hailie Jadoo Jennifer Stong Kristen C Klemenhagen Ann M Philbrick Kathryn Freeman Source Type: research
Beneficial Effects of PIN1 Inhibition on Diabetes Mellitus: A Concise Review
Endocr Metab Immune Disord Drug Targets. 2024 Apr 30. doi: 10.2174/0118715303297663240307060019. Online ahead of print.ABSTRACTType 2 diabetes mellitus is a long-term medical illness in which the body either becomes resistant to insulin or fails to produce it sufficiently. Mostly, combinatorial therapy is required to control blood glucose levels. However, combinatorial therapy has detrimental side effects. The prevalence of the cases and subsequent increases in medical costs of the same intimidate human health globally. While there have been a lot of studies focused on developing diabetic regimens that work to lower blood ...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - May 2, 2024 Category: Endocrinology Authors: Meeramol C Chellappan V Soumya Shriraam Mahadevan M K Kathiravan J Saravanan Soniya Naik Source Type: research
Genetic and inflammatory factors underlying gestational diabetes mellitus: a review
Front Endocrinol (Lausanne). 2024 Apr 17;15:1399694. doi: 10.3389/fendo.2024.1399694. eCollection 2024.ABSTRACTGestational diabetes mellitus (GDM) poses a significant global health concern, impacting both maternal and fetal well-being. Early detection and treatment are imperative to mitigate adverse outcomes during pregnancy. This review delves into the pivotal role of insulin function and the influence of genetic variants, including SLC30A8, CDKAL1, TCF7L2, IRS1, and GCK, in GDM development. These genetic variations affect beta-cell function and insulin activity in crucial tissues, such as muscle, disrupting glucose regul...
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Gyan Watson Ray Qiaoli Zeng Phidelia Kusi Hengli Zhang Taotao Shao Taili Yang Yue Wei Mianqin Li Xiaoqun Che Runmin Guo Source Type: research
Needs-based considerations for the role of low-dose aspirin along the CV risk continuum
Am J Prev Cardiol. 2024 Apr 15;18:100675. doi: 10.1016/j.ajpc.2024.100675. eCollection 2024 Jun.ABSTRACTCardiovascular disease (CVD) remains the leading cause of death worldwide. The risk of a cardiovascular (CV) event is not static and increases along a continuum, making identification and management complex. Aspirin has been the cornerstone of antiplatelet therapy in CV risk reduction and remains the only antiplatelet agent with current guideline recommendations throughout the CV risk continuum. In light of recent trials, the role of aspirin in CVD prevention in asymptomatic patients has been downgraded in clinical guide...
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Francesca Santilli Gerhard Albrecht Michael Blaha Angel Lanas Li Li Dirk Sibbing Source Type: research
The Impact on Birth Outcomes of Sonographic Fetal Weight Estimation in Neonatal Macrosomia
Conclusion Larger EFW increased CD risk among pregnancies with actual neonatal macrosomia. Antenatally suspected macrosomia might alter labor management due to concerns for potential complications, especially when associated with primiparity, diabetes mellitus, or maternal obesity. The increase in the CD rate did not show an association with improved maternal and neonatal outcomes.
Key Points
[...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 2, 2024 Category: Perinatology & Neonatology Authors: Sgayer, Inshirah Nskovica, Karina Murkhovskyi, Iuliia Shqara, Raneen Abu Bilyk, Artyom Lowenstein, Lior Wolf, Maya Frank Tags: Original Article Source Type: research
Exploring type 2 diabetes self-management practices in rural Bangladesh: facilitators, barriers and expectations--a qualitative study protocol
This study will use an exploratory qualitative approach. 16 focus group discussions, 13 in-depth interviews and 9 key informant interviews will be conducted among multilevel stakeholders, including people with T2DM, their caregivers, healthcare providers, health managers/administrators and policy planners. Interviews will be audio-recorded, transcribed, translated and analysed using thematic analysis.
Ethics and dissemination
This research project has been approved by the Monash University Human Research Ethics Committee (project reference number: 39483) and the Ethical Review Committee of the Centre for Injury Prevention...
Source: BMJ Open - May 2, 2024 Category: General Medicine Authors: Chowdhury, H. A., Joham, A. E., Kabir, A., Rahman, A. K. M. F., Ali, L., Harrison, C. L., Billah, B. Tags: Open access, Diabetes and Endocrinology Source Type: research
The comparison of sleep disorders between type-1 diabetic and non-diabetic children and adolescents
ConclusionAccording to the findings of our study, impaired sleep conditions in the T1DM children group were approximately three times the observed ones in the non-diabetic children group. According to our findings, routine evaluation of sleep disorders in diabetic children and adolescents is recommended. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - May 2, 2024 Category: Endocrinology Source Type: research
A case report of type 1 diabetes mellitus coexistent with Charcot –Marie–Tooth type 1A and a literature review
ConclusionIt is not yet clear whether there is a genetic association between the CMTD and diabetes, the genes causing CMTD are perhaps related to T1D and T2D genes. When CMTD and diabetes coexist, the resulting neuropathy is more severe than that observed with either condition alone. We recommend that such patients should strictly control their blood-glucose level to slow down the progression of the disease. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - May 2, 2024 Category: Endocrinology Source Type: research
Deciphering mortality risk of diabetes medications in heart failure patients with diabetes mellitus under triple guideline-directed medical therapy
Scientific evidence regarding the impact of different combinations of diabetes medications in heart failure patients with diabetes mellitus (HFwDM) remains limited. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: İnci Tuğçe Çöllüoğlu, Ahmet Çelik, Naim Ata, Dilek Ural, Anıl Şahin, Mustafa Mahir Ulgu, Emine Arzu Kanık, Şuayip Birinci, Mehmet Birhan Yılmaz Source Type: research
Event-Related Potential Changes Following 12-week Yoga Practice in T2DM Patients: A Randomized Controlled Trial
Conclusion. The 12-week yoga practice improved cognitive performance by enhancing the processes of conflict monitoring and response inhibition. Further, improved cognitive performance postintervention was facilitated by improved glycemic control.PMID:38689456 | DOI:10.1177/15500594241249511 (Source: Clinical EEG and Neuroscience)
Source: Clinical EEG and Neuroscience - May 1, 2024 Category: Neuroscience Authors: Amit Kanthi Singh Deepeshwar Kaligal Chidananda Mahadevappa Vidyashree Dwivedi Krishna Source Type: research
Hyperglycemia impairs EAAT2 glutamate transporter trafficking and glutamate clearance in islets of Langerhans: implications for type 2 diabetes pathogenesis
Am J Physiol Endocrinol Metab. 2024 May 1. doi: 10.1152/ajpendo.00069.2024. Online ahead of print.ABSTRACTPancreatic endocrine cells employ a sophisticated system of paracrine and autocrine signals to synchronize their activities, including glutamate which controls hormone release and β-cell viability by acting on glutamate receptors expressed by endocrine cells. We here investigate whether alteration of the Excitatory Amino Acid Transporter 2 (EAAT2), the major glutamate clearance system in the islet, may occur in type 2 diabetes mellitus (T2DM) and contribute to β-cell dysfunction. Increased EAAT2 intracellular localiz...
Source: American Journal of Physiology. Endocrinology and Metabolism - May 1, 2024 Category: Physiology Authors: Alessandra Galli Stefania Moretti Nevia Dule Eliana Sara Di Cairano Michela Castagna Paola Marciani Cristina Battaglia Federico Bertuzzi Ida Pastore Paolo Fiorina Stefano La Rosa Alberto Davalli Franco Folli Carla Perego Source Type: research
Update on the development of TGR5 agonists for human diseases
Eur J Med Chem. 2024 Apr 28;271:116462. doi: 10.1016/j.ejmech.2024.116462. Online ahead of print.ABSTRACTThe G protein-coupled bile acid receptor 1 (GPBAR1) or TGR5 is widely distributed across organs, including the small intestine, stomach, liver, spleen, and gallbladder. Many studies have established strong correlations between TGR5 and glucose homeostasis, energy metabolism, immune-inflammatory responses, and gastrointestinal functions. These results indicate that TGR5 has a significant impact on the progression of tumor development and metabolic disorders such as diabetes mellitus and obesity. Targeting TGR5 represents...
Source: European Journal of Medicinal Chemistry - May 1, 2024 Category: Chemistry Authors: Wangrui Jin Mingyue Zheng Yihua Chen Hai Xiong Source Type: research
Causal Association Between Diabetes, Body Mass Index and Lichen Sclerosus: A Bidirectional Two-Sample Mendelian Randomization Analysis
CONCLUSION: This MR analysis demonstrated no significant causal relationship between DM and BMI with LS in both directions, which contradicts previous observational studies reporting a positive association. Potential confounding factors may contribute to previously observed associations, and further research is necessary.PMID:38689755 | PMC:PMC11060172 | DOI:10.2147/CCID.S450399 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 1, 2024 Category: Dermatology Authors: Lin Liu Qiuli Zhang Jianmin Chang Kun Yang Source Type: research
Widespread Adoption of Microincision Vitrectomy Surgery Improves Visual Outcomes in Endogenous Endophthalmitis with Poor Initial Vision: A 21-Year Experience in Taiwan
CONCLUSION: In endogenous endophthalmitis patients presenting with poor initial visual acuity, vitrectomy was a better visual prognostic factor. MIVS has allowed more patients to undergo vitrectomy and improved visual outcomes.PMID:38691837 | DOI:10.1080/09273948.2024.2338272 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: Shih-Chou Chen Tsung-Tien Wu Chun-Hao Yin Jin-Shuen Chen Yao-Shen Chen Source Type: research
Genome-wide analysis of two different regions of brain reveals the molecular changes of fertility related genes in rln3a < sup > -/- < /sup > mutants in male Nile tilapia (Oreochromis niloticus)
Gen Comp Endocrinol. 2024 Apr 29:114543. doi: 10.1016/j.ygcen.2024.114543. Online ahead of print.ABSTRACTRelaxin3 (rln3) has been associated with various emotional and cognitive processes, including stress, anxiety, learning, memory, motivational behavior, and circadian rhythm. Notably, previous report revealed that Rln3a played an indispensable role in testicular development and male fertility in Nile tilapia (Oreochromis niloticus). However, the underlying molecular mechanisms remain largely unknown. We found that Rln3a is expressed exclusively in the diencephalon* (Di*) of the brain. Deficiency of Rln3a resulted in a si...
Source: General and Comparative Endocrinology - May 1, 2024 Category: Endocrinology Authors: Tengfei Wu You Wu Yanlong Li Yiyun Du Saining Feng Deshou Wang Linyan Zhou Source Type: research
