Health Technology Assessment: Evaluation of 7 Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Type 2 Diabetes Mellitus
(Source: Risk Management and Healthcare Policy)
Source: Risk Management and Healthcare Policy - April 23, 2024 Category: Health Management Tags: Risk Management and Healthcare Policy Source Type: research
Cancers, Vol. 16, Pages 1625: The Use of Glucagon-like Peptide-1 Receptor Agonists in Patients with Type 2 Diabetes Mellitus Does Not Increase the Risk of Pancreatic Cancer: A U.S.-Based Cohort Study
Conclusion: The use of GLP-1 RAs in patients with type 2 diabetes mellitus (T2DM) does not appear to substantially elevate the risk of pancreatic cancer; in fact, it may potentially exert a protective effect. (Source: Cancers)
Source: Cancers - April 23, 2024 Category: Cancer & Oncology Authors: Mark Ayoub Carol Faris Tajana Juranovic Harleen Chela Ebubekir Daglilar Tags: Article Source Type: research
Choroidal vascularity index as a predictor for the development of retinopathy in diabetic patients
ConclusionsCVI tends to be lower in diabetic patients with or without DR compared to healthy controls. Moreover, patients with DR have a lower CVI than those without DR. CVI can be considered an early and sensitive biomarker for the onset of DR. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 22, 2024 Category: Endocrinology Source Type: research
Artificial intelligence in endocrinology: a comprehensive review
ConclusionsBy embracing AI in endocrinology, a future can be envisioned where medical professionals and AI systems synergistically collaborate, ultimately enhancing the lives of individuals affected by endocrine disorders. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 22, 2024 Category: Endocrinology Source Type: research
Does gestational diabetes mellitus increase the risk of cardiovascular disease? A Mendelian randomization study
ConclusionWomen with a prior history of GDM face an elevated risk of future CAD. This increased risk of CAD cannot be solely attributed to the subsequent onset of diabetes. Regular CAD risk assessment and primary prevention strategies are of paramount importance for women with a history of GDM. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 22, 2024 Category: Endocrinology Source Type: research
Comparison between high-flow nasal oxygen (HFNO) alternated with non-invasive ventilation (NIV) and HFNO and NIV alone in patients with COVID-19: a retrospective cohort study
ConclusionsIn patients with COVID-19, NIV alternating with HFNO was associated with a higher rate of IMV independent of the presence of comorbidities, chest CT score and SpO2/FiO2.Trial registration ClinicalTrials.gov identifier: NCT05579080. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 22, 2024 Category: Research Source Type: research
Factors associated with development of retinopathy in patients with type 2 diabetes mellitus at onset and within three years after diagnosis
. (Source: Scandinavian Journal of Primary Health Care)
Source: Scandinavian Journal of Primary Health Care - April 22, 2024 Category: Primary Care Authors: Kajsa AnderssonAnders HallingBj örn Agvalla Capio Husläkarna Vallda, Kungsbacka, Region Halland, Halmstad, Swedenb Center for Primary Health Care Research, Department of Clinical Sciences Malmö, Lund University, Malmö, Swedenc Department of Research a Source Type: research
Bibliometric and visualized analysis of type 2 diabetic osteoporosis from 2013 to 2022
ConclusionThis was the first bibliometric study of diabetes mellitus and osteoporosis to exclusively examine type 2 diabetes mellitus. Our findings would provide guidance to understand the research frontiers and hot directions in the near future. (Source: Archives of Osteoporosis)
Source: Archives of Osteoporosis - April 22, 2024 Category: Orthopaedics Source Type: research
The current landscape for diabetes treatment: Preventing diabetes-associated CV risk
Despite the risk of atherosclerosis has progressively declined over the past few decades, subjects with type 2 diabetes mellitus (T2DM) continue to experience substantial excess of atherosclerotic cardiovascular disease (ASCVD)-related events. Therefore, there is urgent need to treat ASCVD disease in T2DM earlier, more intensively, and with greater precision. Many factors concur to increase the risk of atherosclerosis, and multifactorial intervention remains the basis for effective prevention or reduction of atherosclerotic events. (Source: Atherosclerosis)
Source: Atherosclerosis - April 22, 2024 Category: Cardiology Authors: Angela Dardano, Cristina Bianchi, Monia Garofolo, Stefano Del Prato Source Type: research
Predictors of late outcomes after concomitant tricuspid valve repair with left-sided valve surgery
ConclusionsConcomitant TV repair with left-sided valve surgery had acceptable outcomes in terms of survival and TR durability. In patients with preoperative TR grade ≥ 3, preoperative patient status had negative impacts on prognosis. (Source: General Thoracic and Cardiovascular Surgery)
Source: General Thoracic and Cardiovascular Surgery - April 22, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research
Serum brain-derived neurotrophic factor levels in type 2 diabetes mellitus patients and its association with cognitive impairment: A meta-analysis
by Wan-li He, Fei-xia Chang, Tao Wang, Bi-xia Sun, Rui-rong Chen, Lian-ping Zhao
ObjectiveTo compare the serum levels of brain-derived neurotrophic factor (BDNF) in type 2 diabetes mellitus (T2DM) patients with healthy controls (HC) and evaluate the BDNF levels in T2DM patients with/without cognitive impairment. MethodsPubMed, EMBASE, and the Cochrane Library databases were searched for the published English literature on BDNF in T2DM patients from inception to December 2022. The BDNF data in the T2DM and HC groups were extracted, and the study quality was evaluated using the Agency for Healthcare Research and Quality. A m...
Source: PLoS One - April 22, 2024 Category: Biomedical Science Authors: Wan-li He Source Type: research
Molecules, Vol. 29, Pages 1904: Molecular Dynamics Simulation of Kir6.2 Variants Reveals Potential Association with Diabetes Mellitus
In this study, we examined the effect of mutations on the Kir6.2 structure using bioinformatics tools and molecular dynamic simulations (SIFT, PolyPhen, SNAP2, PANTHER, PhD&SNP, SNP&Go, I-Mutant, MuPro, MutPred, ConSurf, HOPE, and GROMACS). Our results indicated that M199R, R201H, R206H, and Y330H mutations influence Kir6.2 structure and function and therefore may cause DM. We conclude that MD simulations are useful techniques to predict the effects of mutations on protein structure. In addition, the M199R, R201H, R206H, and Y330H variant in the Kir6.2 protein may be associated with DM. These result...
Source: Molecules - April 22, 2024 Category: Chemistry Authors: Mohamed E. Elangeeb Imadeldin Elfaki Ali M. S. Eleragi Elsadig Mohamed Ahmed Rashid Mir Salem M. Alzahrani Ruqaiah I. Bedaiwi Zeyad M. Alharbi Mohammad Muzaffar Mir Mohammad Rehan Ajmal Faris Jamal Tayeb Jameel Barnawi Tags: Article Source Type: research
Bibliometric and visualized analysis of type 2 diabetic osteoporosis from 2013 to 2022
ConclusionThis was the first bibliometric study of diabetes mellitus and osteoporosis to exclusively examine type 2 diabetes mellitus. Our findings would provide guidance to understand the research frontiers and hot directions in the near future. (Source: Archives of Orthopaedic and Trauma Surgery)
Source: Archives of Orthopaedic and Trauma Surgery - April 22, 2024 Category: Orthopaedics Source Type: research
Folic acid supplementation on inflammation and homocysteine in type 2 diabetes mellitus: systematic review and meta-analysis of randomized controlled trials
Nutrition & Diabetes, Published online: 22 April 2024; doi:10.1038/s41387-024-00282-6Folic acid supplementation on inflammation and homocysteine in type 2 diabetes mellitus: systematic review and meta-analysis of randomized controlled trials (Source: Nutrition and Diabetes)
Source: Nutrition and Diabetes - April 22, 2024 Category: Nutrition Authors: Kabelo Mokgalaboni Given. R. Mashaba Wendy N. Phoswa Sogolo. L. Lebelo Source Type: research
Associations between resting energy expenditure and glycemic parameters in women with obesity without type 2 diabetes mellitus
(Source: Clinical Nutrition)
Source: Clinical Nutrition - April 22, 2024 Category: Nutrition Authors: Mateus de Lima Macena, Micn éias Roberth Pereira, Déborah Tenório Costa de Paula, André Eduardo da Silva Júnior, Nassib Bezerra Bueno Source Type: research
