Does gestational diabetes mellitus increase the risk of cardiovascular disease? A Mendelian randomization study
ConclusionWomen with a prior history of GDM face an elevated risk of future CAD. This increased risk of CAD cannot be solely attributed to the subsequent onset of diabetes. Regular CAD risk assessment and primary prevention strategies are of paramount importance for women with a history of GDM. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - May 1, 2024 Category: Endocrinology Source Type: research
Artificial intelligence in endocrinology: a comprehensive review
ConclusionsBy embracing AI in endocrinology, a future can be envisioned where medical professionals and AI systems synergistically collaborate, ultimately enhancing the lives of individuals affected by endocrine disorders. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - May 1, 2024 Category: Endocrinology Source Type: research
Sensorineural hearing loss among type 2 diabetic patients and its association with peripheral neuropathy: a cross-sectional study from a lower middle-income country
Conclusions
The study highlights the substantial prevalence of SNHL among patients with T2DM and emphasises the importance of targeted audiological care as part of a holistic approach to diabetes management. Addressing HL early may significantly improve communication and overall quality of life. (Source: BMJ Open)
Source: BMJ Open - May 1, 2024 Category: General Medicine Authors: Asghar, S., Ali, Z., Abdullah, A., Naveed, S., Ahmad, M. S., Rafi, T. S. M. Tags: Open access, Diabetes and Endocrinology Source Type: research
IJERPH, Vol. 21, Pages 581: Behind the Hospital Ward: In-Hospital Mortality of Type 2 Diabetes Mellitus Patients in Indonesia (Analysis of National Health Insurance Claim Sample Data)
This study examined in-hospital mortality among patients diagnosed with non-insulin-dependent diabetes mellitus (NIDDM) of ICD-10, or Type 2 Diabetes Mellitus (T2DM), in Indonesia, utilizing hospital claims data spanning from 2017 to 2022 obtained from the Indonesia Health Social Security Agency or Badan Penyelenggara Jaminan Sosial (BPJS) Kesehatan. The analysis, which included 610,809 hospitalized T2DM patients, revealed an in-hospital mortality rate of 6.6%. Factors contributing to an elevated risk of mortality included advanced age, the presence of comorbidities, and severe complications. Additionally, patients receivi...
Source: International Journal of Environmental Research and Public Health - May 1, 2024 Category: Environmental Health Authors: Ede Surya Darmawan Vetty Yulianty Permanasari Latin Vania Nisrina Dian Kusuma Syarif Rahman Hasibuan Nisrina Widyasanti Tags: Article Source Type: research
Protective potential of laughter yoga and clapping exercises on stress level and motor functions in Parkinson ’s disease patients with type 2 diabetes
Background: To examine the protective potential of laughter yoga and clapping exercise on blood glucose regulation on stress level and motor functions of Parkinson ’s disease (PD) patients with type 2 diabetes mellitus (T2DM). (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: R. Kumar, R. Singh, V. Sharma Source Type: research
Cancers, Vol. 16, Pages 1764: Endocrine Immune-Related Adverse Events Are Independent Predictors of Survival in Patients with Lung Cancer
Melpomeni Peppa
Lung cancer (LC) is a serious health problem worldwide. Survival outcomes have improved over time due to the widespread use of novel therapeutic agents, including immune checkpoint inhibitors (ICIs). Endocrine immune-related adverse events (e-irAEs) are common in LC patients treated with ICIs. We performed a retrospective study of patients with LC who received treatment with ICIs at a tertiary referral center between January 2014 and October 2023. In total, 983 LC patients were included in the study. E-irAEs presented at a median time of 4.1 months and included hypothyroidism (15.6%), hyperthyroidism ...
Source: Cancers - May 1, 2024 Category: Cancer & Oncology Authors: Emmanouil Panagiotou Sofia Ntouraki Ioannis A. Vathiotis Maria Effrosyni Livanou Athanasios Trimis Georgios Evangelou Andriani Charpidou Konstantinos Syrigos Melpomeni Peppa Tags: Article Source Type: research
Does Antibiotic Use Increase the Risk of Post-Transplantation Diabetes Mellitus? A Retrospective Study of Renal Transplant Patients
CONCLUSIONS In addition to age, BMI, and TAC concentration after RT, antibiotic use may be a novel factor affecting PTDM. The use of antibiotics may influence the development of PTDM.PMID:38685698 | DOI:10.12659/AOT.943282 (Source: Annals of Transplantation)
Source: Annals of Transplantation - April 30, 2024 Category: Transplant Surgery Authors: Zhenwei Jiang Caomei Xu Huan Hou Xuping Yang Minyan Qian Lian Zuo Peipei Wang Qing Qian Yan Jiang Nan Hu Source Type: research
Role of Clinical Features, Pathogenic and Etiological Characteristics of Community-acquired Pneumonia with Type 2 Diabetes Mellitus in Early Diagnosis
CONCLUSION: Compared with those without diabetes, the infection rates of Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans were higher in patients with combined CAP/T2D.PMID:38686909 | DOI:10.2174/0118715303273741231117060753 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - April 30, 2024 Category: Drugs & Pharmacology Authors: Bai-Yi Liu Dan Zhang Zhu Fan Jing-Jing Jin Cai-Hong Li Rui-Nan Guo Xue-Juan Li Yan Huang Source Type: research
Basal Hyperglycemia Contributes More Than Fifty Percent to Time in Range in Pregnant Women with Type 1 Diabetes
CONCLUSIONS: Basal hyperglycemia was the major contributor to TIR during pregnancy. Along with controlling the postprandial hyperglycemia, pregnant women with T1DM who did not reach the target of TIR may benefit more from the optimization of insulin regimens focusing on reducing basal glucose.PMID:38686666 | DOI:10.1210/clinem/dgae291 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 30, 2024 Category: Endocrinology Authors: Ping Ling Daizhi Yang Chaofan Wang Xueying Zheng Sihui Luo Xubin Yang Hongrong Deng Wen Xu Jinhua Yan Jianping Weng Source Type: research
Role of Clinical Features, Pathogenic and Etiological Characteristics of Community-acquired Pneumonia with Type 2 Diabetes Mellitus in Early Diagnosis
CONCLUSION: Compared with those without diabetes, the infection rates of Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans were higher in patients with combined CAP/T2D.PMID:38686909 | DOI:10.2174/0118715303273741231117060753 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - April 30, 2024 Category: Endocrinology Authors: Bai-Yi Liu Dan Zhang Zhu Fan Jing-Jing Jin Cai-Hong Li Rui-Nan Guo Xue-Juan Li Yan Huang Source Type: research
Bioequivalence of Related GelShield < sup > Ⓡ < /sup > Sustained-Release Formulations of Metformin: A Pooled Pharmacokinetic Analysis
Clin Ther. 2024 Apr 29:S0149-2918(24)00077-8. doi: 10.1016/j.clinthera.2024.03.011. Online ahead of print.ABSTRACTPURPOSE: GlucophageⓇ (Merck Healthcare KGaA, Darmstadt, Germany) is the originator brand of metformin hydrochloride, an oral antidiabetic drug. Metformin is recommended in guidelines as first-line treatment of type 2 diabetes mellitus and increasingly in related insulin-resistant conditions, such as prediabetes and polycystic ovary syndrome. The GelShieldⓇ sustained-release formulation tablet of GlucophageⓇ has been improved from the historic version marketed in 2000. Bioequivalence has been demonstrated ...
Source: Clinical Therapeutics - April 30, 2024 Category: Drugs & Pharmacology Authors: Axel Krebs-Brown Kerstin M G Brand Marco A F Nogueira Filho Sumedh Gaikwad Yvonne Schnaars Source Type: research
Construction and Validation Study of a Model for Predicting the Risk of Pulmonary Complications in Elderly Patients with Multiple Rib Fractures
CONCLUSIONS: The column-line diagram model of pulmonary complications in patients with MRF constructed in this study showed good discriminative and calibration performance in both internal and external validation, which is helpful for clinicians to identify individuals at high risk of pulmonary complications as early as possible, and thus can be recommended for clinical use.PMID:38687856 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 30, 2024 Category: Complementary Medicine Authors: Chenchen Yang Hengfa Ge Aifeng Gong Source Type: research
Prediction and causal inference of hyperuricemia using gut microbiota
This study aimed to determine the relationship between HUA and GM. The microbiome of 224 men and 254 women aged 40 years was analyzed through next-generation sequencing and machine learning. We obtained GM data through 16S rRNA-based sequencing of the fecal samples, finding that alpha-diversity by Shannon index was significantly low in the HUA group. Linear discriminant effect size analysis detected a high abundance of the genera Collinsella and Faecalibacterium in the HUA and non-HUA groups. Based on light gradient boosting machine learning, we propose that HUA can be predicted with high AUC using four clinical characteri...
Source: Atherosclerosis - April 30, 2024 Category: Cardiology Authors: Yuna Miyajima Shigehiro Karashima Ren Mizoguchi Masaki Kawakami Kohei Ogura Kazuhiro Ogai Aoi Koshida Yasuo Ikagawa Yuta Ami Qiunan Zhu Hiromasa Tsujiguchi Akinori Hara Shin Kurihara Hiroshi Arakawa Hiroyuki Nakamura Ikumi Tamai Hidetaka Nambo Shigefumi O Source Type: research
Modification of lipoprotein metabolism and function driving atherogenesis in diabetes
Atherosclerosis. 2024 Apr 17:117545. doi: 10.1016/j.atherosclerosis.2024.117545. Online ahead of print.ABSTRACTType 2 diabetes mellitus (T2DM) is a chronic metabolic disease, characterized by raised blood glucose levels and impaired lipid metabolism resulting from insulin resistance and relative insulin deficiency. In diabetes, the peculiar plasma lipoprotein phenotype, consisting in higher levels of apolipoprotein B-containing lipoproteins, hypertriglyceridemia, low levels of HDL cholesterol, elevated number of small, dense LDL, and increased non-HDL cholesterol, results from an increased synthesis and impaired clearance ...
Source: Atherosclerosis - April 30, 2024 Category: Cardiology Authors: Lorenzo Luciani Matteo Pedrelli Paolo Parini Source Type: research
The current landscape for diabetes treatment: Preventing diabetes-associated CV risk
Atherosclerosis. 2024 Apr 23:117560. doi: 10.1016/j.atherosclerosis.2024.117560. Online ahead of print.ABSTRACTDespite the risk of atherosclerosis has progressively declined over the past few decades, subjects with type 2 diabetes mellitus (T2DM) continue to experience substantial excess of atherosclerotic cardiovascular disease (ASCVD)-related events. Therefore, there is urgent need to treat ASCVD disease in T2DM earlier, more intensively, and with greater precision. Many factors concur to increase the risk of atherosclerosis, and multifactorial intervention remains the basis for effective prevention or reduction of ather...
Source: Atherosclerosis - April 30, 2024 Category: Cardiology Authors: Angela Dardano Cristina Bianchi Monia Garofolo Stefano Del Prato Source Type: research
