Emerging Perspectives on the Impact of Diabetes Mellitus and Anti-Diabetic Drugs on Premenstrual Syndrome. A Narrative Review
AbstractDiabetes mellitus (DM) and premenstrual syndrome (PMS) are global health challenges. Both disorders are often linked to a range of physical and psychological symptoms that significantly impact the quality of life of many women. Yet, the exact relation between DM and PMS is not clear, and the management of both conditions poses a considerable challenge. In this review, we aimed to investigate the interplay between DM, anti-diabetic drugs, and the different theories and symptoms of PMS. Female sex hormones are implicated in the pathophysiology of PMS and can also impair blood glucose control. In addition, patients wi...
Source: Diabetes Therapy - April 26, 2024 Category: Endocrinology Source Type: research
Endocrine disrupting chemicals: gestational diabetes and beyond
Gestational Diabetes Mellitus (GDM) has been on the rise for the last two decades along with the growing incidence of obesity. The ubiquitous use of Endocrine-Disrupting Chemicals (EDCs) worldwide has been ass... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - April 26, 2024 Category: Endocrinology Authors: Tridip Mitra, Richa Gulati, Krithika Ramachandran, Rohan Rajiv, Elizabeth Ann L. Enninga, Chris K Pierret, Sajeetha Kumari R and Rajiv Janardhanan Tags: Review Source Type: research
Effect of switch from flash glucose monitoring to flash glucose monitoring with real-time alarms on hypoglycaemia in people with type 1 diabetes mellitus
We aimed to evaluate the utility of the FreeStyle Libre 2 device for reducing time below range level 1 and level 2 compared with the Freestyle Libre device (without alarms) in people with type 1 diabetes mellitus. We conducted longitudinal observational follow-up study of a cohort of 100 people with type 1 diabetes mellitus who had switched from FreeStyle Libre to FreeStyle Libre 2 as part of routine clinical practice. Three months after switching to FreeStyle Libre 2, compared with results with FreeStyle Libre, there were a significant improvements in time below range level 1 (p = 0.02) and level 2 (p (Source: Primary Care Diabetes)
Source: Primary Care Diabetes - April 26, 2024 Category: Primary Care Authors: A. Guti érrez-Pastor, JA Quesada, MM Soler-Martínez, C. Carratalá Munuera, FJ Pomares-Gómez Source Type: research
The glucose tolerance peak parameter revisited. Definition for a novel use in Gestational Diabetes Mellitus confirmation
ConclusionsGTp, an index derived exclusively from the OGTT peak glycaemia, proves valuable in confirming the presence of GDM. The GTp could be used to confirm the presence of GDM under necessity of a second OGTT as test confirmation in pregnant woman. A cut-off of < 0. 36 has a specificity of 100% and a sensitivity of 75% for the diagnosis of GDM. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 26, 2024 Category: Endocrinology Source Type: research
The latest emerging drugs for the treatment of diabetic cardiomyopathy
Expert Opin Pharmacother. 2024 Apr 30:1-14. doi: 10.1080/14656566.2024.2347468. Online ahead of print.ABSTRACTINTRODUCTION: Diabetic cardiomyopathy (DCM) is a serious complication of diabetes mellitus involving multiple pathophysiologic mechanisms. In addition to hypoglycemic agents commonly used in diabetes, metabolism-related drugs, natural plant extracts, melatonin, exosomes, and rennin-angiotensin-aldosterone system are cardioprotective in DCM. However, there is a lack of systematic summarization of drugs for DCM.AREAS COVERED: In this review, the authors systematically summarize the most recent drugs used for the trea...
Source: Expert Opinion on Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Minghao Li Lin Liu Chunyu Zhang Li Deng Yi Zhong Bin Liao Xiuying Li Ying Wan Jian Feng Source Type: research
Novel subtype of obesity influencing the outcomes of sleeve gastrectomy: Familial aggregation of obesity
CONCLUSION: FAO patients is associated with decreased mid-to-long-term weight loss outcomes; the alleviation of T2DM, hyperlipidemia and NAFLD; and decreased incidence of acid reflux postoperatively.PMID:38659480 | PMC:PMC11036498 | DOI:10.3748/wjg.v30.i13.1887 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 25, 2024 Category: Gastroenterology Authors: Ze-Yu Wang Yun-Fei Qu Tian-Ming Yu Zeng-Lin Liu Yu-Gang Cheng Ming-Wei Zhong San-Yuan Hu Source Type: research
Impact of a primary care pharmacy unit on the optimization of pharmacological treatment of type 2 diabetic patients
CONCLUSIONS: Review of the pharmacological treatment of patients with type 2 diabetes mellitus by a pharmacist or pharmacologist facilitates its optimization.PMID:38663157 | DOI:10.1016/j.aprim.2024.102945 (Source: Atencion Primaria)
Source: Atencion Primaria - April 25, 2024 Category: Primary Care Authors: Laura Canadell-Vilarrasa Tom às Palanques-Pastor Cec ília Campabadal-Prats Clara Salom-Garrigues Silvia Conde-Giner Ferran Bejarano-Romero Source Type: research
Novel subtype of obesity influencing the outcomes of sleeve gastrectomy: Familial aggregation of obesity
CONCLUSION: FAO patients is associated with decreased mid-to-long-term weight loss outcomes; the alleviation of T2DM, hyperlipidemia and NAFLD; and decreased incidence of acid reflux postoperatively.PMID:38659480 | PMC:PMC11036498 | DOI:10.3748/wjg.v30.i13.1887 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 25, 2024 Category: Gastroenterology Authors: Ze-Yu Wang Yun-Fei Qu Tian-Ming Yu Zeng-Lin Liu Yu-Gang Cheng Ming-Wei Zhong San-Yuan Hu Source Type: research
Colorectal Cancer and Subsequent Diabetes Risk: A Population-based Cohort Study in Taiwan
CONCLUSION: Patients with CRC are associated with an elevated risk of diabetes mellitus, and long-term chemotherapy, particularly involving capecitabine, increases diabetes mellitus risk. Thus, monitoring blood glucose levels is crucial for patients with CRC, especially during extended chemotherapy.PMID:38661006 | DOI:10.1210/clinem/dgae257 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 25, 2024 Category: Endocrinology Authors: Hsin-Yin Hsu Yih-Jong Chern Min-Shu Hsu Tzu-Lin Yeh Ming-Chieh Tsai Jing-Rong Jhuang Cheng-Tzu Hsieh Chun-Ju Chiang Wen-Chung Lee Lee-Ching Hwang Kuo-Liong Chien Source Type: research
The latest emerging drugs for the treatment of diabetic cardiomyopathy
Expert Opin Pharmacother. 2024 Apr 25. doi: 10.1080/14656566.2024.2347468. Online ahead of print.ABSTRACTINTRODUCTION: Diabetic cardiomyopathy (DCM) is a serious complication of diabetes mellitus involving multiple pathophysiologic mechanisms. In addition to hypoglycemic agents commonly used in diabetes, metabolism-related drugs, natural plant extracts, melatonin, exosomes, and rennin-angiotensin-aldosterone system are cardioprotective in DCM. However, there is a lack of systematic summarization of drugs for DCM.AREAS COVERED: In this review, the authors systematically summarize the most recent drugs used for the treatment...
Source: Expert Opinion on Pharmacotherapy - April 25, 2024 Category: Drugs & Pharmacology Authors: Minghao Li Lin Liu Chunyu Zhang Li Deng Yi Zhong Bin Liao Xiuying Li Ying Wan Jian Feng Source Type: research
Association between glycemic status and the risk of gastric cancer in pre-and postmenopausal women: A nationwide cohort study
CONCLUSIONS: The risk of gastric cancer escalates with deteriorating glycemic status in a dose-response manner. Diabetes mellitus is linked with an elevated risk of gastric cancer in postmenopausal women.PMID:38663524 | DOI:10.1016/j.annepidem.2024.04.009 (Source: Annals of Epidemiology)
Source: Annals of Epidemiology - April 25, 2024 Category: Epidemiology Authors: Kyung Hee Han Yoon Jin Choi Tae Il Kim Noh Hyun Park Kyung-do Han Dong Ho Lee Source Type: research
Differential inhibition of sildenafil and macitentan on saxagliptin metabolism
Toxicol Appl Pharmacol. 2024 Apr 24;486:116934. doi: 10.1016/j.taap.2024.116934. Online ahead of print.ABSTRACTThe development of diabetes mellitus (DM) is generally accompanied by erectile dysfunction (ED) and pulmonary arterial hypertension (PAH), which increases the use of combination drug therapy and the risk of drug-drug interactions. Saxagliptin for the treatment of DM, sildenafil for the treatment of ED and PAH, and macitentan for the treatment of PAH are all substrates of CYP3A4, which indicates their potential involvement in drug-drug interactions. Therefore, we investigated potential pharmacokinetic interactions ...
Source: Toxicology and Applied Pharmacology - April 25, 2024 Category: Toxicology Authors: Ge-Xin Dai Wei Tan Yuxin Shen Dongdong Lin Ren-Ai Xu Qianmeng Lin Zhen Wei Source Type: research
Impact of a primary care pharmacy unit on the optimization of pharmacological treatment of type 2 diabetic patients
CONCLUSIONS: Review of the pharmacological treatment of patients with type 2 diabetes mellitus by a pharmacist or pharmacologist facilitates its optimization.PMID:38663157 | DOI:10.1016/j.aprim.2024.102945 (Source: Atencion Primaria)
Source: Atencion Primaria - April 25, 2024 Category: Primary Care Authors: Laura Canadell-Vilarrasa Tom às Palanques-Pastor Cec ília Campabadal-Prats Clara Salom-Garrigues Silvia Conde-Giner Ferran Bejarano-Romero Source Type: research
Novel subtype of obesity influencing the outcomes of sleeve gastrectomy: Familial aggregation of obesity
CONCLUSION: FAO patients is associated with decreased mid-to-long-term weight loss outcomes; the alleviation of T2DM, hyperlipidemia and NAFLD; and decreased incidence of acid reflux postoperatively.PMID:38659480 | PMC:PMC11036498 | DOI:10.3748/wjg.v30.i13.1887 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 25, 2024 Category: Gastroenterology Authors: Ze-Yu Wang Yun-Fei Qu Tian-Ming Yu Zeng-Lin Liu Yu-Gang Cheng Ming-Wei Zhong San-Yuan Hu Source Type: research
Novel subtype of obesity influencing the outcomes of sleeve gastrectomy: Familial aggregation of obesity
CONCLUSION: FAO patients is associated with decreased mid-to-long-term weight loss outcomes; the alleviation of T2DM, hyperlipidemia and NAFLD; and decreased incidence of acid reflux postoperatively.PMID:38659480 | PMC:PMC11036498 | DOI:10.3748/wjg.v30.i13.1887 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 25, 2024 Category: Gastroenterology Authors: Ze-Yu Wang Yun-Fei Qu Tian-Ming Yu Zeng-Lin Liu Yu-Gang Cheng Ming-Wei Zhong San-Yuan Hu Source Type: research
