Cardiovascular evaluation and endothelial dysfunction in Cushing syndrome following remission: a prospective study
ConclusionsRemission in CS improves some cardiovascular parameters. ADMA and ET-1 are not reliable markers for endothelial dysfunction in CS. Metabolic improvements may not directly reflect on serum concentrations of TNF- α and IL-1β following remission of CS. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - March 1, 2024 Category: Endocrinology Source Type: research
What Is Cushing Syndrome?
This JAMA Patient Page describes Cushing syndrome and its signs, symptoms, diagnosis, and treatment. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - March 1, 2024 Category: General Medicine Source Type: research
Cardiovascular evaluation and endothelial dysfunction in Cushing syndrome following remission: a prospective study
ConclusionsRemission in CS improves some cardiovascular parameters. ADMA and ET-1 are not reliable markers for endothelial dysfunction in CS. Metabolic improvements may not directly reflect on serum concentrations of TNF- α and IL-1β following remission of CS. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - March 1, 2024 Category: Endocrinology Source Type: research
IDF23-0560 The prevalence of Endogenous Cushing syndrome (CS) in adults with diabetes mellitus in Eastern India
(Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 1, 2024 Category: Endocrinology Authors: A. Gupta, M. Bera, A. Baidya, R. Ahmed Tags: Other Complications Source Type: research
Multi-omics Investigations in Endocrine Systems and Their Clinical Implications
Adv Exp Med Biol. 2024;1443:187-209. doi: 10.1007/978-3-031-50624-6_10.ABSTRACTInnovative techniques such as the "omics" can be a powerful tool for the understanding of intracellular pathways involved in homeostasis maintenance and identification of new potential therapeutic targets against endocrine-metabolic disorders. Over the last decades, proteomics has been extensively applied in the study of a wide variety of human diseases, including those involving the endocrine system. Among the most endocrine-related disorders investigated by proteomics in humans are diabetes mellitus and thyroid, pituitary, and reproductive sys...
Source: Adv Data - February 27, 2024 Category: Epidemiology Authors: Rodrigo Antonio Peliciari-Garcia Carolina Fonseca de Barros Ayla Secio-Silva Diogo de Barros Peruchetti Renata Marino Romano Paula Bargi-Souza Source Type: research
Multi-omics Investigations in Endocrine Systems and Their Clinical Implications
Adv Exp Med Biol. 2024;1443:187-209. doi: 10.1007/978-3-031-50624-6_10.ABSTRACTInnovative techniques such as the "omics" can be a powerful tool for the understanding of intracellular pathways involved in homeostasis maintenance and identification of new potential therapeutic targets against endocrine-metabolic disorders. Over the last decades, proteomics has been extensively applied in the study of a wide variety of human diseases, including those involving the endocrine system. Among the most endocrine-related disorders investigated by proteomics in humans are diabetes mellitus and thyroid, pituitary, and reproductive sys...
Source: Advances in Experimental Medicine and Biology - February 27, 2024 Category: Research Authors: Rodrigo Antonio Peliciari-Garcia Carolina Fonseca de Barros Ayla Secio-Silva Diogo de Barros Peruchetti Renata Marino Romano Paula Bargi-Souza Source Type: research
Multi-omics Investigations in Endocrine Systems and Their Clinical Implications
Adv Exp Med Biol. 2024;1443:187-209. doi: 10.1007/978-3-031-50624-6_10.ABSTRACTInnovative techniques such as the "omics" can be a powerful tool for the understanding of intracellular pathways involved in homeostasis maintenance and identification of new potential therapeutic targets against endocrine-metabolic disorders. Over the last decades, proteomics has been extensively applied in the study of a wide variety of human diseases, including those involving the endocrine system. Among the most endocrine-related disorders investigated by proteomics in humans are diabetes mellitus and thyroid, pituitary, and reproductive sys...
Source: Adv Data - February 27, 2024 Category: Epidemiology Authors: Rodrigo Antonio Peliciari-Garcia Carolina Fonseca de Barros Ayla Secio-Silva Diogo de Barros Peruchetti Renata Marino Romano Paula Bargi-Souza Source Type: research
Multi-omics Investigations in Endocrine Systems and Their Clinical Implications
Adv Exp Med Biol. 2024;1443:187-209. doi: 10.1007/978-3-031-50624-6_10.ABSTRACTInnovative techniques such as the "omics" can be a powerful tool for the understanding of intracellular pathways involved in homeostasis maintenance and identification of new potential therapeutic targets against endocrine-metabolic disorders. Over the last decades, proteomics has been extensively applied in the study of a wide variety of human diseases, including those involving the endocrine system. Among the most endocrine-related disorders investigated by proteomics in humans are diabetes mellitus and thyroid, pituitary, and reproductive sys...
Source: Advances in Experimental Medicine and Biology - February 27, 2024 Category: Research Authors: Rodrigo Antonio Peliciari-Garcia Carolina Fonseca de Barros Ayla Secio-Silva Diogo de Barros Peruchetti Renata Marino Romano Paula Bargi-Souza Source Type: research
Diagnosis and management of secondary adrenal crisis
Rev Endocr Metab Disord. 2024 Feb 27. doi: 10.1007/s11154-024-09877-x. Online ahead of print.ABSTRACTAdrenal crisis (AC) is a life threatening acute adrenal insufficiency (AI) episode which can occur in patients with primary AI but also secondary AI (SAI), tertiary AI (TAI) and iatrogenic AI (IAI). In SAI, TAI and IAI, AC may develop when the HPA axis is unable to mount an adequate glucocorticoid response to severe stress due to pituitary or hypothalamic disruption. It manifests as an acute deterioration in multi-organ homeostasis that, if untreated, leads to shock and death. Despite the availability of effective preventiv...
Source: ENDOCR REV - February 27, 2024 Category: Endocrinology Authors: Luciana Martel-Duguech Jonathan Poirier Isabelle Bourdeau Andr é Lacroix Source Type: research
Diagnosis and management of secondary adrenal crisis
Rev Endocr Metab Disord. 2024 Feb 27. doi: 10.1007/s11154-024-09877-x. Online ahead of print.ABSTRACTAdrenal crisis (AC) is a life threatening acute adrenal insufficiency (AI) episode which can occur in patients with primary AI but also secondary AI (SAI), tertiary AI (TAI) and iatrogenic AI (IAI). In SAI, TAI and IAI, AC may develop when the HPA axis is unable to mount an adequate glucocorticoid response to severe stress due to pituitary or hypothalamic disruption. It manifests as an acute deterioration in multi-organ homeostasis that, if untreated, leads to shock and death. Despite the availability of effective preventiv...
Source: ENDOCR REV - February 27, 2024 Category: Endocrinology Authors: Luciana Martel-Duguech Jonathan Poirier Isabelle Bourdeau Andr é Lacroix Source Type: research
Diagnosis and management of secondary adrenal crisis
AbstractAdrenal crisis (AC) is a life threatening acute adrenal insufficiency (AI) episode which can occur in patients with primary AI but also secondary AI (SAI), tertiary AI (TAI) and iatrogenic AI (IAI). In SAI, TAI and IAI, AC may develop when the HPA axis is unable to mount an adequate glucocorticoid response to severe stress due to pituitary or hypothalamic disruption. It manifests as an acute deterioration in multi-organ homeostasis that, if untreated, leads to shock and death. Despite the availability of effective preventive strategies, its prevalence is increasing in patients with SAI, TAI and IAI due to more freq...
Source: Reviews in Endocrine and Metabolic Disorders - February 27, 2024 Category: Endocrinology Source Type: research
Utility of Simple and Non-Invasive Strategies Alternative to Inferior
Petrosal Sinus Sampling and Peripheral CRH Stimulation in Differential Diagnosis
of ACTH-Dependent Cushing Syndrome
Horm Metab Res DOI: 10.1055/a-2236-0864We aimed to evaluate the utility of simple, cost-effective, and non-invasive
strategies alternative to BIPSS and peripheral CRH stimulation in differential
diagnosis of ACTH-dependent CS. First, we performed ROC analysis to evaluate the
performance of various tests for differential diagnosis of ACTH-dependent CS in
our cohort (CD, n=76 and EAS, n=23) and derived their optimal
cut-offs. Subsequently, combining various demographic (gender), clinical
(hypokalemia), biochemical (plasma ACTH, HDDST, peripheral CRH stimulation) and...
Source: Hormone and Metabolic Research - February 16, 2024 Category: Endocrinology Authors: Attri, Bhawna Goyal, Alpesh Kalaivani, Mani Kandasamy, Devasenathipathy Gupta, Yashdeep Agarwal, Shipra Shamim, Shamim A. Damle, Nishikant Sharma, Mehar Chand Jyotsna, Viveka P. Suri, Ashish Tandon, Nikhil Tags: Original Article: Endocrine Care Source Type: research
