Adrenocorticotropic hormone-secreting phaeochromocytoma as a cause of treatment-resistant hypertension and recurrent pulmonary emboli
We report an unusual case of a patient presenting with Cushing's syndrome caused by a phaeochromocytoma secreting adrenocorticotropic hormone (ACTH). The patient had a history of treatment-resistant hypertension, secondary amenorrhoea and tendency towards hypokalaemia. She had multiple signs of Cushing's syndrome, such as swelling, bruising, abdominal striae and proximal myopathy. Hypokalaemia is more common in patients with ectopic ACTH-secretion than other causes of Cushing's syndrome. Computed tomography, adrenal vein sampling and biochemistry could confirm an ACTH-secreting phaeochromocytoma. It is important to conside...
Source: Journal of the Royal College of Physicians of Edinburgh - November 8, 2023 Category: General Medicine Authors: Shobitha Vollmer Henrik Borg Source Type: research
Diagnostic performance of an automated immunoassay for salivary cortisol
Ann Endocrinol (Paris). 2023 Nov 3:S0003-4266(23)00715-1. doi: 10.1016/j.ando.2023.10.007. Online ahead of print.ABSTRACTAutomated immunoanalysis (AI) is an interesting alternative for measuring salivary cortisol, as the gold-standard HPLC-MS/MS method is not yet readily available. The aim of this study was to evaluate the diagnostic performance of salivary cortisol immunoassay on the iSYS immunoanalyzer in adrenal dynamic tests. Cortisol was measured on iSYS and on HPLC-MS/MS in saliva samples collected after 1mg-dexamethasone suppression test (DST) in 115 patients suspected of Cushing syndrome, and during Synacthen® sti...
Source: Annales d'Endocrinologie - November 5, 2023 Category: Endocrinology Authors: Christelle Laguillier Morizot Fid éline Bonnet Serrano Marie-Cl émence Leguy Mili ça Simeonovic Catherine See Corinne Zientek Mickael Soussan Lucas Bouys J érôme Bertherat Jean Guibourdenche Source Type: research
Diagnostic performance of an automated immunoassay for salivary cortisol
Ann Endocrinol (Paris). 2023 Nov 3:S0003-4266(23)00715-1. doi: 10.1016/j.ando.2023.10.007. Online ahead of print.ABSTRACTAutomated immunoanalysis (AI) is an interesting alternative for measuring salivary cortisol, as the gold-standard HPLC-MS/MS method is not yet readily available. The aim of this study was to evaluate the diagnostic performance of salivary cortisol immunoassay on the iSYS immunoanalyzer in adrenal dynamic tests. Cortisol was measured on iSYS and on HPLC-MS/MS in saliva samples collected after 1mg-dexamethasone suppression test (DST) in 115 patients suspected of Cushing syndrome, and during Synacthen® sti...
Source: Annales d'Endocrinologie - November 5, 2023 Category: Endocrinology Authors: Christelle Laguillier Morizot Fid éline Bonnet Serrano Marie-Cl émence Leguy Mili ça Simeonovic Catherine See Corinne Zientek Mickael Soussan Lucas Bouys J érôme Bertherat Jean Guibourdenche Source Type: research
Diagnostic performance of an automated immunoassay for salivary cortisol
Ann Endocrinol (Paris). 2023 Nov 3:S0003-4266(23)00715-1. doi: 10.1016/j.ando.2023.10.007. Online ahead of print.ABSTRACTAutomated immunoanalysis (AI) is an interesting alternative for measuring salivary cortisol, as the gold-standard HPLC-MS/MS method is not yet readily available. The aim of this study was to evaluate the diagnostic performance of salivary cortisol immunoassay on the iSYS immunoanalyzer in adrenal dynamic tests. Cortisol was measured on iSYS and on HPLC-MS/MS in saliva samples collected after 1mg-dexamethasone suppression test (DST) in 115 patients suspected of Cushing syndrome, and during Synacthen® sti...
Source: Annales d'Endocrinologie - November 5, 2023 Category: Endocrinology Authors: Christelle Laguillier Morizot Fid éline Bonnet Serrano Marie-Cl émence Leguy Mili ça Simeonovic Catherine See Corinne Zientek Mickael Soussan Lucas Bouys J érôme Bertherat Jean Guibourdenche Source Type: research
Diagnostic performance of an automated immunoassay for salivary cortisol
Ann Endocrinol (Paris). 2023 Nov 3:S0003-4266(23)00715-1. doi: 10.1016/j.ando.2023.10.007. Online ahead of print.ABSTRACTAutomated immunoanalysis (AI) is an interesting alternative for measuring salivary cortisol, as the gold-standard HPLC-MS/MS method is not yet readily available. The aim of this study was to evaluate the diagnostic performance of salivary cortisol immunoassay on the iSYS immunoanalyzer in adrenal dynamic tests. Cortisol was measured on iSYS and on HPLC-MS/MS in saliva samples collected after 1mg-dexamethasone suppression test (DST) in 115 patients suspected of Cushing syndrome, and during Synacthen® sti...
Source: Annales d'Endocrinologie - November 5, 2023 Category: Endocrinology Authors: Christelle Laguillier Morizot Fid éline Bonnet Serrano Marie-Cl émence Leguy Mili ça Simeonovic Catherine See Corinne Zientek Mickael Soussan Lucas Bouys J érôme Bertherat Jean Guibourdenche Source Type: research
Diagnostic performance of an automated immunoassay for salivary cortisol
Ann Endocrinol (Paris). 2023 Nov 3:S0003-4266(23)00715-1. doi: 10.1016/j.ando.2023.10.007. Online ahead of print.ABSTRACTAutomated immunoanalysis (AI) is an interesting alternative for measuring salivary cortisol, as the gold-standard HPLC-MS/MS method is not yet readily available. The aim of this study was to evaluate the diagnostic performance of salivary cortisol immunoassay on the iSYS immunoanalyzer in adrenal dynamic tests. Cortisol was measured on iSYS and on HPLC-MS/MS in saliva samples collected after 1mg-dexamethasone suppression test (DST) in 115 patients suspected of Cushing syndrome, and during Synacthen® sti...
Source: Annales d'Endocrinologie - November 5, 2023 Category: Endocrinology Authors: Christelle Laguillier Morizot Fid éline Bonnet Serrano Marie-Cl émence Leguy Mili ça Simeonovic Catherine See Corinne Zientek Mickael Soussan Lucas Bouys J érôme Bertherat Jean Guibourdenche Source Type: research
Diagnostic performance of an automated immunoassay for salivary cortisol
Ann Endocrinol (Paris). 2023 Nov 3:S0003-4266(23)00715-1. doi: 10.1016/j.ando.2023.10.007. Online ahead of print.ABSTRACTAutomated immunoanalysis (AI) is an interesting alternative for measuring salivary cortisol, as the gold-standard HPLC-MS/MS method is not yet readily available. The aim of this study was to evaluate the diagnostic performance of salivary cortisol immunoassay on the iSYS immunoanalyzer in adrenal dynamic tests. Cortisol was measured on iSYS and on HPLC-MS/MS in saliva samples collected after 1mg-dexamethasone suppression test (DST) in 115 patients suspected of Cushing syndrome, and during Synacthen® sti...
Source: Annales d'Endocrinologie - November 5, 2023 Category: Endocrinology Authors: Christelle Laguillier Morizot Fid éline Bonnet Serrano Marie-Cl émence Leguy Mili ça Simeonovic Catherine See Corinne Zientek Mickael Soussan Lucas Bouys J érôme Bertherat Jean Guibourdenche Source Type: research
Laparoscopic Transperitoneal Adrenalectomy for Adrenal Tumors in Children: Technical Considerations and Surgical Experience
Conclusions: In children with well-circumscribed, localized, and noninvasive adrenal tumors, LA is feasible, effective, and safe with all advantages of minimally invasive surgery.PMID:37862564 | DOI:10.1089/lap.2023.0160 (Source: Adv Data)
Source: Adv Data - October 20, 2023 Category: Epidemiology Authors: Ankur Mandelia Sabaretnam Mayilvaganan Prathibha B Naik Pujana Kanneganti Source Type: research
Cushing's syndrome of the orbit: congestive orbitopathy and optic neuropathy associated with steroids
Orbit. 2023 Oct 19:1-4. doi: 10.1080/01676830.2023.2268158. Online ahead of print.ABSTRACTA 56-year-old female with a history of chronic systemic steroid use for asthma control displayed orbital congestion, exophthalmos, a mild abduction deficit, and optic neuropathy. Laboratory workup was unrevealing. Neuroimaging showed increased orbital fat compartments, though the orbital fat was unremarkable on biopsy. The patient was diagnosed with iatrogenic Cushing's syndrome of the orbit and underwent orbital decompression. Early published literature declared this orbitopathy benign. However, newer cases describe more pathologic c...
Source: Orbit - October 19, 2023 Category: Opthalmology Authors: Leroy Ekeh Hanan Ibrahim Firas Askar Alireza Meysami Brittany A Simmons Source Type: research
