Cushing's syndrome of the orbit: congestive orbitopathy and optic neuropathy associated with steroids

Orbit. 2023 Oct 19:1-4. doi: 10.1080/01676830.2023.2268158. Online ahead of print.ABSTRACTA 56-year-old female with a history of chronic systemic steroid use for asthma control displayed orbital congestion, exophthalmos, a mild abduction deficit, and optic neuropathy. Laboratory workup was unrevealing. Neuroimaging showed increased orbital fat compartments, though the orbital fat was unremarkable on biopsy. The patient was diagnosed with iatrogenic Cushing's syndrome of the orbit and underwent orbital decompression. Early published literature declared this orbitopathy benign. However, newer cases describe more pathologic changes, suggesting the disease is diagnosed later and/or treatment is delayed.PMID:37855748 | DOI:10.1080/01676830.2023.2268158

Source: Orbit - October 19, 2023 Category: Opthalmology Authors: Leroy Ekeh Hanan Ibrahim Firas Askar Alireza Meysami Brittany A Simmons Source Type: research