Prevalence of endocrine disorders in 304 premenopausal women referred with oligomenorrhoea
CONCLUSIONS: We found higher prevalence of CS in patients with oligomenorrhoea even in the absence of clinical signs. Therefore, we suggest routine screening for CS during the evaluation of patients with oligomenorrhoea and/or PCOS. The likelihood of CS is greater in patients with high androgen, especially DHEA-S levels.PMID:38497394 | DOI:10.5603/ep.96737 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Hamiyet Yilmaz Mustafa Demirpence Umit Belet Ibrahim Ozkili ç Ayfer Colak Savas Ceylan Muammer Sar ıkaya Erdem Yasar Source Type: research
A challenging case of ectopic ACTH-dependent Cushing's syndrome due to medullary thyroid carcinoma
Endokrynol Pol. 2024;75(1):115-116. doi: 10.5603/ep.96863.ABSTRACTNot required for Clinical Vignette.PMID:38497400 | DOI:10.5603/ep.96863 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Maria Komisarz-Calik Paulina Sarba Ma łgorzata Trofimiuk-Müldner Grzegorz Soko łowski Joanna Szpor Alicja Hubalewska-Dydejczyk Source Type: research
Prevalence of endocrine disorders in 304 premenopausal women referred with oligomenorrhoea
CONCLUSIONS: We found higher prevalence of CS in patients with oligomenorrhoea even in the absence of clinical signs. Therefore, we suggest routine screening for CS during the evaluation of patients with oligomenorrhoea and/or PCOS. The likelihood of CS is greater in patients with high androgen, especially DHEA-S levels.PMID:38497394 | DOI:10.5603/ep.96737 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Hamiyet Yilmaz Mustafa Demirpence Umit Belet Ibrahim Ozkili ç Ayfer Colak Savas Ceylan Muammer Sar ıkaya Erdem Yasar Source Type: research
A challenging case of ectopic ACTH-dependent Cushing's syndrome due to medullary thyroid carcinoma
Endokrynol Pol. 2024;75(1):115-116. doi: 10.5603/ep.96863.ABSTRACTNot required for Clinical Vignette.PMID:38497400 | DOI:10.5603/ep.96863 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Maria Komisarz-Calik Paulina Sarba Ma łgorzata Trofimiuk-Müldner Grzegorz Soko łowski Joanna Szpor Alicja Hubalewska-Dydejczyk Source Type: research
Prevalence of endocrine disorders in 304 premenopausal women referred with oligomenorrhoea
CONCLUSIONS: We found higher prevalence of CS in patients with oligomenorrhoea even in the absence of clinical signs. Therefore, we suggest routine screening for CS during the evaluation of patients with oligomenorrhoea and/or PCOS. The likelihood of CS is greater in patients with high androgen, especially DHEA-S levels.PMID:38497394 | DOI:10.5603/ep.96737 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - March 18, 2024 Category: Endocrinology Authors: Hamiyet Yilmaz Mustafa Demirpence Umit Belet Ibrahim Ozkili ç Ayfer Colak Savas Ceylan Muammer Sar ıkaya Erdem Yasar Source Type: research
Adipose tissue in cortisol excess: What Cushing's syndrome can teach us?
Biochem Pharmacol. 2024 Mar 15:116137. doi: 10.1016/j.bcp.2024.116137. Online ahead of print.ABSTRACTEndogenous Cushing's syndrome (CS) is a rare condition due to prolonged exposure to elevated circulating cortisol levels that features its typical phenotype characterised by moon face, proximal myopathy, easy bruising, hirsutism in females and a centripetal distribution of body fat. Given the direct and indirect effects of hypercortisolism, CS is a severe disease burdened by increased cardio-metabolic morbidity and mortality in which visceral adiposity plays a leading role. Although not commonly found in clinical setting, e...
Source: Biochemical Pharmacology - March 17, 2024 Category: Drugs & Pharmacology Authors: Alessandro Bavaresco Pierluigi Mazzeo Martina Lazzara Mattia Barbot Source Type: research
Cushing's syndrome caused by adrenocortical oncocytoma: A case report
Oncol Lett. 2024 Feb 28;27(4):177. doi: 10.3892/ol.2024.14310. eCollection 2024 Apr.ABSTRACTAdrenal cortical eosinophilic adenoma usually presents as non-functional adrenal tumor but may lead to Cushing's syndrome in patients. The present article reports a patient with Cushing's syndrome caused by right adrenocortical oncocytoma. The patient was treated in Urology Department of Wuchuan People's Hospital (Zunyi, China) in November 2022 because of hirsutism, weight gain and hypertension. A laparoscopic right adrenal tumor resection was performed using an abdominal approach. Following surgery, blood pressure and heart rate of...
Source: Oncology Letters - March 11, 2024 Category: Cancer & Oncology Authors: Chengren Gou Qingsong Jian Maoqiang Tian Jinghai Li Yi Zhang Zhenyu Guo Source Type: research
A systematic review of primary large cell neuroendocrine carcinoma of the prostate
ConclusionLCNEC of the prostate is a rare disease that can occur de novo or transformation from prostatic adenocarcinoma. Most patients present at an advanced stage with poor prognosis and are treated with conventional chemotherapy regimens. Patients who had better outcomes were those who were diagnosed at an early stage and received treatment with surgery or radiation and androgen deprivation therapy (ADT). There was one case with an exceptional outcome that included a treatment regimen of M6620 and chemotherapy. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 7, 2024 Category: Cancer & Oncology Source Type: research
Fulminant ectopic Cushing's syndrome caused by metastatic small intestine neuroendocrine tumour - a case report and review of the literature
Acta Gastroenterol Belg. 2024 Jan-Mar;87(1):48-51. doi: 10.51821/87.1.11872.ABSTRACTCushing's syndrome (CS) secondary to adrenocorticotropic hormone (ACTH) producing tumours is a severe condition with a challenging diagnosis. Ectopic ACTH-secretion often involves neuroendocrine tumours (NET) in the respiratory tract. ACTH-secreting small intestine neuro-endocrine tumours (siNET) are extremely rare entities barely reported in literature. This review is illustrated by the case of a 75-year old woman with fulminant ectopic CS caused by a ACTH-secreting metastatic siNET. Severe hypokalemia, fluid retention and refractory hyper...
Source: Acta Gastro-Enterologica Belgica - March 3, 2024 Category: Gastroenterology Authors: B Alliet C Severi T Veekmans J Cuypers H Topal C M Deroose T Roskams M Bex J Dekervel Source Type: research
