The growing impact of Acta Gastro-Enterologica Belgica
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):1-2.NO ABSTRACTPMID:33639686 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: T Vanuytsel N Lanthier Source Type: research

High- versus low-dose proton pump inhibitors post endoscopic hemostasis in hemodialysis cases with peptic ulcer bleeding
This study aimed to compare post-endoscopic high- versus low-dose proton pump inhibitors (PPIs) for peptic ulcer bleeding in patients undergoing regular HD. This prospective study comprised 200 patients on regular hemodialysis having emergency peptic ulcer bleeding confirmed at endoscopy and managed with endoscopic hemostasis. Half of the patients received high-dose intensive regimen and the other half received the standard regimen. Patients who were suspected to have recurrent bleeding underwent a second endoscopy for bleeding control. The primary outcome measure was rate of recurrent bleeding during period of hospitaliza...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: A A Salman M A Salman M D Sarhan H El-Din Shaaban M Yousef A Ibrahim M Tourky A Youssef M El Sherbiny Source Type: research

Role of endoscopy in suspicion of atrophic gastritis with and without intestinal metaplasia in comparison to histopathology
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):9-17.ABSTRACTBACKGROUND AND STUDY AIMS: Atrophic gastritis (AG) and intestinal metaplasia (IM) are established premalignant gastric lesions. Many studies documented a poor correlation between esophagogastroduodenoscopy (EGD) and histopathological (HP) findings of precancerous gastric lesions. The aim was to bridge the gap between endoscopy and HP in detection of chronic gastritis, AG and IM.PATIENTS AND METHODS: a prospective single-center study involved 150 patients with endoscopic criteria of gastric lesions with upper gastrointestinal symptoms referred for upper GI endoscopy m...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: H Ibrahim A Shams El-Deen Z A Kasemy M Saad A A Sakr Source Type: research

Impact of antithrombotics on the fecal immunochemical test for colorectal cancer screening : a multi-center Belgian experience
CONCLUSION: Although antithrombotics were prescribed more frequently in male and older patients, detection of AP/CRC was similar. Despite increased GI symptoms, false positive FIT was similar with antithrombotics.PMID:33639689 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: L Wauters V R H Van der Voort P Dobbels K Hendrickx V Casneuf J Vandervoort Source Type: research

Risk of hepatocellular carcinoma and fibrosis evolution in hepatitis C patients with severe fibrosis or cirrhosis treated with direct acting antiviral agents
CONCLUSIONS: DAA treatment does not seem to be associated with HCC promotion after HCV eradication in patients with severe fibrosis stages. DAA-induced SVR is associated with a reduced estimation of fibrosis.PMID:33639690 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: C Hamoir Y Horsmans P St ärkel G Dahlqvist S Negrin Dastis N Lanthier Source Type: research

Comorbidities and concomitant medications in patients with chronic hepatitis C virus infection receiving second-generation direct-acting antiviral regimens in Belgium: an observational study
CONCLUSION: Physicians are aware of the potential for DDIs with DAAs, but improved alignment between clinical practice and theoretical recommendations is required.PMID:33639691 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: S Bourgeois J P Mulkay M Cool X Verhelst G Robaeys L Lasser V Lefebvre I Colle C Van Steenkiste J Decaestecker S Coulon K Venken T Vanwolleghem Source Type: research

Serum biomarkers as an alternative to vibration controlled transient elastography in liver fibrosis staging in chronic hepatitis C
CONCLUSION: Before therapy, FIB-4 had the best accuracy in predicting advanced fibrosis whereas APRI and GUCI score were the best indices post-treatment.PMID:33639692 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: P Debnath S Nair P Rathi P Junare S Jain S Chandnani A Singh Q Contractor Source Type: research

Platelet safety range before splenectomy for hypersplenism: based on 244 cases of splenectomy in hepatolenticular degeneration patients
CONCLUSION: For HLD patients with hypersplenism, it is safe and effective to conduct splenectomy under PLT
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: S T Wang H Feng H Peng L Huang F H Zhou Q S Yu Source Type: research

Tolvaptan reduces the required amount of albumin infusion in patients with decompensated cirrhosis with uncontrolled ascites : a multicenter retrospective propensity score-matched cohort study
CONCLUSIONS: Tolvaptan reduced the use of albumin infusion in patients with decompensated cirrhosis and was effective and acceptable for uncontrolled ascites.PMID:33639694 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: Y Suzuki A Naganuma T Hoshino T Hatanaka T Ueno M Namikawa D Takizawa H Arai H Suzuki H Takagi H Tojima Y Yamazaki K Sato S Kakizaki T Uraoka Source Type: research

A change in the timing for starting systemic therapies for hepatocellular carcinoma: the comparison of sorafenib and lenvatinib as the first-line treatment
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):65-72.ABSTRACTAIM: The aim of this retrospective multicenter study was to evaluate the differences in the timing for starting systemic therapies as the first-line treatment for hepatocellular carcinoma (HCC).METHODS: A total of 375 patients with HCC treated with sorafenib from May 2009 to March 2018 and 56 patients treated with lenvatinib from March 2018 to November 2018 at our affiliated hospitals were included in this study.RESULTS: The median ages of the sorafenib and lenvatinib groups were 71.0 (interquartile range [IQR]: 64.0-77.0) and 73.5 (IQR: 68.0 -80.0) years old, and 3...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: T Hatanaka S Kakizaki T Nagashima T Ueno M Namikawa H Tojima D Takizawa A Naganuma H Arai K Sato N Harimoto K Shirabe T Uraoka Source Type: research

Current ERCP practice in Belgium: the BSGIE survey
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):73-77.ABSTRACTBACKGROUND AND STUDY AIMS: Data on procedural outcome and quality of endoscopic retrograde cholangiopancreatography (ERCP) in Belgian practice are scarce. The aim of this study is to assess current status of ERCP-performance in Belgium.METHODS: National multi-institutional survey (online questionnaire) among members of the Belgian Society of Gastrointestinal Endoscopy (BSGIE), conducted in the period June-August 2018. The RIZIV/INAMI provided real-life data on the total number of ERCPs performed in Belgium.RESULTS: Forty-five responders completed the survey (for 43 ...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: C Snauwaert X Dekoninck T Moreels Source Type: research

Venous thromboembolism in patients with inflammatory bowel disease: review of literature and practical algorithms
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):79-85.ABSTRACTInflammatory bowel disease (IBD) is associated with several extra-intestinal complications, including venous thromboembolism (VTE). In patients with IBD, VTE occurs at younger age and is associated with higher recurrence and mortality rates as compared to patients without IBD. The risk appears to be higher during active disease and hospitalization. In this review we target the importance of prophylaxis and aim to describe strategies for treatment of VTE in patients with IBD. More awareness is needed, given the fact that VTE is often preventable with appropriate phar...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: L Coremans B Strubbe H Peeters Source Type: research

Fecal microbiota transplantation in hepatic encephalopathy : a review of the current evidence and future perspectives
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):87-90.ABSTRACTHepatic encephalopathy (HE) is a leading cause of hospitalization and morbimortality in advanced cirrhosis with limited therapeutic options available. Given the paramount role of gut microbiota in HE, and the efficacy of fecal microbiota transplantation (FMT) in other diseases, this review intends to summarize the evidence supporting the safety, efficacy and future perspectives of FMT in HE. Current evidence, despite being scarce, points towards FMT being a safe, effective and tolerable procedure in HE. Some unanswered questions remain about the optimal dose, the ad...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: E Afecto A Ponte S Fernandes J Silva C Gomes J Correia J Carvalho Source Type: research

The "Fonds Georges Broh ée": a longstanding Belgian national initiative to stimulate research in hepatogastroenterology
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):91-94.ABSTRACTThe Fonds Brohée/Brohée fund was created in 1964 at the initiative of 16 Belgian physicians, in the memory of Georges Brohée, the founder of the Belgian Society of Gastroenterology in 1928 and of its Journal in 1933, first published under the name "Le Journal Belge de Gastro-entérologie", then until today as "Acta Gastro-Enterologica Belgica". The goal of the Fonds is to stimulate research in the field of gastroenterology in Belgium, by awarding a young researcher (
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: I Borbath R Fiasse P Van Hootegem Source Type: research

Recent advances in the approach to hepatopulmonary syndrome and portopulmonary hypertension
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):95-99.ABSTRACTLiver disease, cirrhosis and portal hypertension can be complicated by pulmonary vascular disease, which may affect prognosis and influence liver transplantation (LT) candidacy. Pulmonary vascular complications comprise hepatopulmonary syndrome (HPS) and portopulmonary hypertension (POPH). Although these two conditions develop on a same background and share a common trigger, pulmonary responses are distinct and occur at different anatomical sites of the pulmonary circulation. HPS affects 10-30% of patients referred for LT, and is characterized by gas exchange abnorm...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: S Raevens A Geerts L Devisscher H Van Vlierberghe C Van Steenkiste I Colle Source Type: research

Belgian consensus guideline on the management of hemorrhoidal disease
CONCLUSIONS: The current guidelines for the management of hemorrhoidal disease include recommendations for the clinical evaluation of hemorrhoidal disorders, and their conservative, instrumental and surgical management.PMID:33639701 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: H De Schepper G Coremans M A Denis P Dewint M Duinslaeger I Gijsen P Haers N Komen C Remue P Roelandt M Somers M Surmont D Van de Putte S Van den Broeck C Van Kemseke D De Looze Source Type: research

Vitamine B12 deficiency in children: a diagnostic challenge
We report six paediatric patients with different aetiologies of vitB12 deficiency ranging from a subtle to a more overt presentation. VitB12 deficiency is a diagnostic challenge due to the lack of consensus on normal values of vitB12 and its co-markers (folate, holotranscobalamin, methylmalonic acid, homocysteine) and the lack in specificity and sensitivity of the serum vitB12 analysis. All cases were treated with parenteral vitB12. Last decades, evidence supporting high dose oral treatment being as effective as the intramuscular (IM) therapy, also in children, is growing.PMID:33639702 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: J Van Vlaenderen J Christiaens M Van Winckel R De Bruyne S Vande Velde S Van Biervliet Source Type: research

Mantle cell lymphoma simulating inflammatory bowel disease
We report a case of colorectal involvement by a mantle cell lymphoma (MCL) that had been considered before as inflammatory bowel disease. Diagnosis of low-grade MCL can be difficult, and here we highlight the importance of thorough histopathological examination in case of supposed inflammatory bowel disease that does not react to therapy.PMID:33639703 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: F Lifrange R de Wind C Spilleboudt I Karfis A Van Gossum P Demetter Source Type: research

Interferon-alpha-2a as a salvage treatment for hemorrhagic enteritis associated with Epstein-Barr Virus reactivation: a case report
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):129-130.ABSTRACTEpstein-Barr virus [EBV] is a virus that infects almost all humans worldwide. After the acute phase of the infection, it stays in a latent form in B lymphocytes. EBV reactivation tends to occur in immunosuppressed patients. EBV reactivation may involve the gastrointestinal tract ; it has been associated mainly with colitis, but hemorrhagic enteritis has been poorly reported. Treatment usually includes antivirals. However, our patient did not respond to conventional treatment, so interferon alpha-2a was given as a salvage treatment. To our knowledge, this is the fi...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: D Lankenau-Vela F De la Garza-Salazar P Colunga-Pedraza D Jaime-Villal ón Source Type: research

Infected hepatic cyst complicating urinary sepsis
We report here the case of an 86-year old patient who has been treated by a percutaneous drainage for an infected solitary hepatic cyst due to urinary sepsis. She was admitted to the Department of Internal Medicine for epigastric pain with fever and chills. The patient was treated for a urinary tract infection 3 weeks ago by her General Practitioner. On admission, blood tests showed 21 620 neutrophils per microliter with a C-reactive protein level at 443.7 mg/L, procalcitonin> 200 ng/mL, total bilirubin at 1.43 mg/dL, lactate dehydrogenase at 666 U/L and alanine aminotransferase at 227 U/L. Urinalysis and hemocultures h...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: A Coulon I Ould-Nana J-Y Wilputte Source Type: research

Gastro-intestinal symptoms are associated with a lower in-hospital mortality rate in frail older patients hospitalized for COVID-19
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):135-136.NO ABSTRACTPMID:33639706 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: N Lanthier C Mahiat S Henrard P St ärkel I Gilard I De Brauwer P Cornette B Boland Source Type: research

Ischemic rectal necrosis after aortic valve replacement surgery successfully treated with conservative management
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):137-138.NO ABSTRACTPMID:33639707 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: E Dias J Santos-Antunes S Lopes G Macedo Source Type: research

A rare case of acute hepatitis caused by Komboucha tea
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):139-141.NO ABSTRACTPMID:33639708 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: C Steger T Vandamme P H Steger Source Type: research

Muscular rim sign at endoscopic ultrasound in a patient with a suspected cyst of the pancreatic head
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):143-144.NO ABSTRACTPMID:33639709 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: G Marasco R Sadik Source Type: research

Gastrointestinal bleeding with joint pain
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):145-146.NO ABSTRACTPMID:33639710 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: A K Singh C L Birda J Samanta S K Sinha R Kochhar Source Type: research

A curious case of diarrhea
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):147.NO ABSTRACTPMID:33639711 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: S De Meulder F J Van de Mierop Source Type: research

The growing impact of Acta Gastro-Enterologica Belgica
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):1-2.NO ABSTRACTPMID:33639686 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: T Vanuytsel N Lanthier Source Type: research

High- versus low-dose proton pump inhibitors post endoscopic hemostasis in hemodialysis cases with peptic ulcer bleeding
This study aimed to compare post-endoscopic high- versus low-dose proton pump inhibitors (PPIs) for peptic ulcer bleeding in patients undergoing regular HD. This prospective study comprised 200 patients on regular hemodialysis having emergency peptic ulcer bleeding confirmed at endoscopy and managed with endoscopic hemostasis. Half of the patients received high-dose intensive regimen and the other half received the standard regimen. Patients who were suspected to have recurrent bleeding underwent a second endoscopy for bleeding control. The primary outcome measure was rate of recurrent bleeding during period of hospitaliza...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: A A Salman M A Salman M D Sarhan H El-Din Shaaban M Yousef A Ibrahim M Tourky A Youssef M El Sherbiny Source Type: research

Role of endoscopy in suspicion of atrophic gastritis with and without intestinal metaplasia in comparison to histopathology
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):9-17.ABSTRACTBACKGROUND AND STUDY AIMS: Atrophic gastritis (AG) and intestinal metaplasia (IM) are established premalignant gastric lesions. Many studies documented a poor correlation between esophagogastroduodenoscopy (EGD) and histopathological (HP) findings of precancerous gastric lesions. The aim was to bridge the gap between endoscopy and HP in detection of chronic gastritis, AG and IM.PATIENTS AND METHODS: a prospective single-center study involved 150 patients with endoscopic criteria of gastric lesions with upper gastrointestinal symptoms referred for upper GI endoscopy m...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: H Ibrahim A Shams El-Deen Z A Kasemy M Saad A A Sakr Source Type: research

Impact of antithrombotics on the fecal immunochemical test for colorectal cancer screening : a multi-center Belgian experience
CONCLUSION: Although antithrombotics were prescribed more frequently in male and older patients, detection of AP/CRC was similar. Despite increased GI symptoms, false positive FIT was similar with antithrombotics.PMID:33639689 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: L Wauters V R H Van der Voort P Dobbels K Hendrickx V Casneuf J Vandervoort Source Type: research

Risk of hepatocellular carcinoma and fibrosis evolution in hepatitis C patients with severe fibrosis or cirrhosis treated with direct acting antiviral agents
CONCLUSIONS: DAA treatment does not seem to be associated with HCC promotion after HCV eradication in patients with severe fibrosis stages. DAA-induced SVR is associated with a reduced estimation of fibrosis.PMID:33639690 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: C Hamoir Y Horsmans P St ärkel G Dahlqvist S Negrin Dastis N Lanthier Source Type: research

Comorbidities and concomitant medications in patients with chronic hepatitis C virus infection receiving second-generation direct-acting antiviral regimens in Belgium: an observational study
CONCLUSION: Physicians are aware of the potential for DDIs with DAAs, but improved alignment between clinical practice and theoretical recommendations is required.PMID:33639691 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: S Bourgeois J P Mulkay M Cool X Verhelst G Robaeys L Lasser V Lefebvre I Colle C Van Steenkiste J Decaestecker S Coulon K Venken T Vanwolleghem Source Type: research

Serum biomarkers as an alternative to vibration controlled transient elastography in liver fibrosis staging in chronic hepatitis C
CONCLUSION: Before therapy, FIB-4 had the best accuracy in predicting advanced fibrosis whereas APRI and GUCI score were the best indices post-treatment.PMID:33639692 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: P Debnath S Nair P Rathi P Junare S Jain S Chandnani A Singh Q Contractor Source Type: research

Platelet safety range before splenectomy for hypersplenism: based on 244 cases of splenectomy in hepatolenticular degeneration patients
CONCLUSION: For HLD patients with hypersplenism, it is safe and effective to conduct splenectomy under PLT
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: S T Wang H Feng H Peng L Huang F H Zhou Q S Yu Source Type: research

Tolvaptan reduces the required amount of albumin infusion in patients with decompensated cirrhosis with uncontrolled ascites : a multicenter retrospective propensity score-matched cohort study
CONCLUSIONS: Tolvaptan reduced the use of albumin infusion in patients with decompensated cirrhosis and was effective and acceptable for uncontrolled ascites.PMID:33639694 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: Y Suzuki A Naganuma T Hoshino T Hatanaka T Ueno M Namikawa D Takizawa H Arai H Suzuki H Takagi H Tojima Y Yamazaki K Sato S Kakizaki T Uraoka Source Type: research

A change in the timing for starting systemic therapies for hepatocellular carcinoma: the comparison of sorafenib and lenvatinib as the first-line treatment
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):65-72.ABSTRACTAIM: The aim of this retrospective multicenter study was to evaluate the differences in the timing for starting systemic therapies as the first-line treatment for hepatocellular carcinoma (HCC).METHODS: A total of 375 patients with HCC treated with sorafenib from May 2009 to March 2018 and 56 patients treated with lenvatinib from March 2018 to November 2018 at our affiliated hospitals were included in this study.RESULTS: The median ages of the sorafenib and lenvatinib groups were 71.0 (interquartile range [IQR]: 64.0-77.0) and 73.5 (IQR: 68.0 -80.0) years old, and 3...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: T Hatanaka S Kakizaki T Nagashima T Ueno M Namikawa H Tojima D Takizawa A Naganuma H Arai K Sato N Harimoto K Shirabe T Uraoka Source Type: research

Current ERCP practice in Belgium: the BSGIE survey
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):73-77.ABSTRACTBACKGROUND AND STUDY AIMS: Data on procedural outcome and quality of endoscopic retrograde cholangiopancreatography (ERCP) in Belgian practice are scarce. The aim of this study is to assess current status of ERCP-performance in Belgium.METHODS: National multi-institutional survey (online questionnaire) among members of the Belgian Society of Gastrointestinal Endoscopy (BSGIE), conducted in the period June-August 2018. The RIZIV/INAMI provided real-life data on the total number of ERCPs performed in Belgium.RESULTS: Forty-five responders completed the survey (for 43 ...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: C Snauwaert X Dekoninck T Moreels Source Type: research

Venous thromboembolism in patients with inflammatory bowel disease: review of literature and practical algorithms
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):79-85.ABSTRACTInflammatory bowel disease (IBD) is associated with several extra-intestinal complications, including venous thromboembolism (VTE). In patients with IBD, VTE occurs at younger age and is associated with higher recurrence and mortality rates as compared to patients without IBD. The risk appears to be higher during active disease and hospitalization. In this review we target the importance of prophylaxis and aim to describe strategies for treatment of VTE in patients with IBD. More awareness is needed, given the fact that VTE is often preventable with appropriate phar...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: L Coremans B Strubbe H Peeters Source Type: research

Fecal microbiota transplantation in hepatic encephalopathy : a review of the current evidence and future perspectives
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):87-90.ABSTRACTHepatic encephalopathy (HE) is a leading cause of hospitalization and morbimortality in advanced cirrhosis with limited therapeutic options available. Given the paramount role of gut microbiota in HE, and the efficacy of fecal microbiota transplantation (FMT) in other diseases, this review intends to summarize the evidence supporting the safety, efficacy and future perspectives of FMT in HE. Current evidence, despite being scarce, points towards FMT being a safe, effective and tolerable procedure in HE. Some unanswered questions remain about the optimal dose, the ad...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: E Afecto A Ponte S Fernandes J Silva C Gomes J Correia J Carvalho Source Type: research

The "Fonds Georges Broh ée": a longstanding Belgian national initiative to stimulate research in hepatogastroenterology
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):91-94.ABSTRACTThe Fonds Brohée/Brohée fund was created in 1964 at the initiative of 16 Belgian physicians, in the memory of Georges Brohée, the founder of the Belgian Society of Gastroenterology in 1928 and of its Journal in 1933, first published under the name "Le Journal Belge de Gastro-entérologie", then until today as "Acta Gastro-Enterologica Belgica". The goal of the Fonds is to stimulate research in the field of gastroenterology in Belgium, by awarding a young researcher (
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: I Borbath R Fiasse P Van Hootegem Source Type: research

Recent advances in the approach to hepatopulmonary syndrome and portopulmonary hypertension
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):95-99.ABSTRACTLiver disease, cirrhosis and portal hypertension can be complicated by pulmonary vascular disease, which may affect prognosis and influence liver transplantation (LT) candidacy. Pulmonary vascular complications comprise hepatopulmonary syndrome (HPS) and portopulmonary hypertension (POPH). Although these two conditions develop on a same background and share a common trigger, pulmonary responses are distinct and occur at different anatomical sites of the pulmonary circulation. HPS affects 10-30% of patients referred for LT, and is characterized by gas exchange abnorm...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: S Raevens A Geerts L Devisscher H Van Vlierberghe C Van Steenkiste I Colle Source Type: research

Belgian consensus guideline on the management of hemorrhoidal disease
CONCLUSIONS: The current guidelines for the management of hemorrhoidal disease include recommendations for the clinical evaluation of hemorrhoidal disorders, and their conservative, instrumental and surgical management.PMID:33639701 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: H De Schepper G Coremans M A Denis P Dewint M Duinslaeger I Gijsen P Haers N Komen C Remue P Roelandt M Somers M Surmont D Van de Putte S Van den Broeck C Van Kemseke D De Looze Source Type: research

Vitamine B12 deficiency in children: a diagnostic challenge
We report six paediatric patients with different aetiologies of vitB12 deficiency ranging from a subtle to a more overt presentation. VitB12 deficiency is a diagnostic challenge due to the lack of consensus on normal values of vitB12 and its co-markers (folate, holotranscobalamin, methylmalonic acid, homocysteine) and the lack in specificity and sensitivity of the serum vitB12 analysis. All cases were treated with parenteral vitB12. Last decades, evidence supporting high dose oral treatment being as effective as the intramuscular (IM) therapy, also in children, is growing.PMID:33639702 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: J Van Vlaenderen J Christiaens M Van Winckel R De Bruyne S Vande Velde S Van Biervliet Source Type: research

Mantle cell lymphoma simulating inflammatory bowel disease
We report a case of colorectal involvement by a mantle cell lymphoma (MCL) that had been considered before as inflammatory bowel disease. Diagnosis of low-grade MCL can be difficult, and here we highlight the importance of thorough histopathological examination in case of supposed inflammatory bowel disease that does not react to therapy.PMID:33639703 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: F Lifrange R de Wind C Spilleboudt I Karfis A Van Gossum P Demetter Source Type: research

Interferon-alpha-2a as a salvage treatment for hemorrhagic enteritis associated with Epstein-Barr Virus reactivation: a case report
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):129-130.ABSTRACTEpstein-Barr virus [EBV] is a virus that infects almost all humans worldwide. After the acute phase of the infection, it stays in a latent form in B lymphocytes. EBV reactivation tends to occur in immunosuppressed patients. EBV reactivation may involve the gastrointestinal tract ; it has been associated mainly with colitis, but hemorrhagic enteritis has been poorly reported. Treatment usually includes antivirals. However, our patient did not respond to conventional treatment, so interferon alpha-2a was given as a salvage treatment. To our knowledge, this is the fi...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: D Lankenau-Vela F De la Garza-Salazar P Colunga-Pedraza D Jaime-Villal ón Source Type: research

Infected hepatic cyst complicating urinary sepsis
We report here the case of an 86-year old patient who has been treated by a percutaneous drainage for an infected solitary hepatic cyst due to urinary sepsis. She was admitted to the Department of Internal Medicine for epigastric pain with fever and chills. The patient was treated for a urinary tract infection 3 weeks ago by her General Practitioner. On admission, blood tests showed 21 620 neutrophils per microliter with a C-reactive protein level at 443.7 mg/L, procalcitonin> 200 ng/mL, total bilirubin at 1.43 mg/dL, lactate dehydrogenase at 666 U/L and alanine aminotransferase at 227 U/L. Urinalysis and hemocultures h...
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: A Coulon I Ould-Nana J-Y Wilputte Source Type: research

Gastro-intestinal symptoms are associated with a lower in-hospital mortality rate in frail older patients hospitalized for COVID-19
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):135-136.NO ABSTRACTPMID:33639706 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: N Lanthier C Mahiat S Henrard P St ärkel I Gilard I De Brauwer P Cornette B Boland Source Type: research

Ischemic rectal necrosis after aortic valve replacement surgery successfully treated with conservative management
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):137-138.NO ABSTRACTPMID:33639707 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: E Dias J Santos-Antunes S Lopes G Macedo Source Type: research

A rare case of acute hepatitis caused by Komboucha tea
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):139-141.NO ABSTRACTPMID:33639708 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: C Steger T Vandamme P H Steger Source Type: research

Muscular rim sign at endoscopic ultrasound in a patient with a suspected cyst of the pancreatic head
Acta Gastroenterol Belg. 2021 Jan-Mar;84(1):143-144.NO ABSTRACTPMID:33639709 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 28, 2021 Category: Gastroenterology Authors: G Marasco R Sadik Source Type: research