Comparison between tunneling and standard endoscopic submucosal dissection for treatment of large esophageal superficial neoplasm.
CONCLUSIONS: T-ESD is a safe and effective method for treating large esophageal superficial neoplasms with a faster dissection speed than s-ESD, but postoperative strictures may be encountered for lesions involving more than three-fourths of the circumference or longer than 3 cm. PMID: 31950800 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Cold snare endoscopic resection of nonpedunculated colorectal polyps larger than 10 mm. A retrospective series.
CONCLUSION: CSP for advanced, non-pedunculated lesions is feasible, effective and extremely safe. PMID: 31950801 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Hepatitis C virus (HCV) prevalence estimation in the adult general population in Belgium : a meta-analysis.
CONCLUSIONS: We believe that the quantitative measurement by the meta-analysis will be more reliable for their use in the design of a screening strategy or in the development of prevention campaigns as compared to the prevalence estimations performed at local level. PMID: 31950802 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Von-Willebrand factor as a predictor of three-month mortality in patients with liver cirrhosis compared to MELD score.
Authors: Curakova Ristovska E, Genadieva-Dimitrova M, Caloska-Ivanova V, Misevski J Abstract INTRODUCTION AND AIM: Endothelial dysfunction is involved in the pathogenesis of portal hypertension and in the progression of liver disease. As an indicator of endothelial dysfunction, von Willebrand factor (vWF-Ag) can be a useful mortality predictor in patients with liver cirrhosis. The aim of the study is to compare the predictive value of vWF-Ag with the predictive value of MELD score regarding the three-month mortality in patients with liver cirrhosis. MATERIALS AND METHODS: In 70 patients with cirrhosis and porta...
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Role of computed tomography in prediction of gastrointestinal fistula in patients with acute pancreatitis.
CONCLUSION: CT is helpful in predicting GIF in patients with AP. PMID: 31950804 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Can the matrix metalloproteinases 2 and 9 predict the course of acute pancreatitis in previously healthy patients?
CONCLUSION: The determination of a single laboratory marker, which is the level of metalloproteinase-2 or metalloproteinase-9, is characterized by sensitivity and specificity comparable to that of multifactor prognostic scoring systems. PMID: 31950805 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Efficacy and safety of magnetic guided capsule gastroscopy in gastric diseases.
Authors: Rauya E, Sha O, Darwazeh R, Zhang BQ Abstract The current mainstay of screening and diagnosis for gastric diseases is conventional standard gastroscopy. However, it is invasive and uncomfortable procedure for the patients especially in case of non-sedative procedures and other adverse effects related to conscious sedation anesthesia. Recently, a magnetic guided capsule gastroscopy (MGCG) was introduced to overcome these challenges. It is a safe and pleasant procedure with no involvement of sedation and no risks of cross-infection between patients. In addition, this method is anticipated to be an alternativ...
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Potential clinical scenarios of tumour budding in colorectal cancer.
Authors: Dawson H, Blank A, Zlobec I, Lugli A Abstract Tumour budding, defined as single tumour cells or clusters of 4 tumour cells or less detached from the main tumour body, is a wellestablished indicator of aggressive tumour biology in colorectal cancer. As a marker of tumour dissemination, evidence points towards tumour budding as a morphological correlate of epithelialmesenchymal type changes in the tumour microenvironment. Despite many studies in the literature going back decades, tumour budding has not been systematically integrated in colorectal cancer reporting protocols. The recently published proceedings...
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Fecal microbiota transplantation in ulcerative colitis.
CONCLUSION: FMT seems to be a promising and safe therapy in the management of UC. Further research, with larger cohorts, will be needed to confirm this and to determine the optimal FMT procedure. PMID: 31950808 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Endoscopic vacuum-assisted closure therapy for the treatment of oesophageal anastomotic leaks.
We report here endoscopic vacuum-assisted closure therapy as a novel endoscopic treatment for the management of oesophageal anastomotic leaks. Endoscopic vacuum-assisted closure therapy is a minimally invasive method to treat anastomotic leakage by positioning an open-pored polyurethane sponge and a suction tube connected to a wound drainage system into the opening of the wound cavity. This multidisciplinary endoscopic and surgical approach is a successful therapy for the management of suture dehiscence with oesophageal anastomotic leaks after thoracic surgery or oesophageal perforations. PMID: 31950809 [PubMed - in pr...
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

A man with abdominal pain and eosinophilia : tissue is the issue.
Authors: Crapé L, Strubbe B, Cesmeli E, de Clerck F Abstract A 24-year-old male presented with abdominal pain, postprandial vomiting and weight loss. Lab results showed an elevated serum eosinophil count and CT-scan demonstrated a thickened antral, duodenal and jejunal wall. Repetitive endoscopic mucosal biopsies were normal. Work-up of eosinophilia-associated gastro-intestinal disorders excluded secondary causes. Bone marrow showed an elevated eosinophil count without arguments for a primary hypereosinophilic syndrome. Endoscopic ultrasound-guided fine needle biopsy detected a strongly elevated number of eo...
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Impact of liver inflammation on whole body insulin resistance : a case report on primary biliary cholangitis.
In this report, we present the case of a patient who was diagnosed with primary biliary cholangitis and metabolic syndrome. Initial evaluation also revealed diabetes with elevated fasting plasma glucose and glycated hemoglobin. After eight weeks of treatment with ursodeoxycholic acid, a complete normalization of the hepatic biological tests was observed. A few months later, while body weight and abdominal perimeter remained stable, fasting blood glucose and glycated hemoglobin decreased significantly, compatible with diabetes disappearance. This finding supports the concept that the inflamed liver plays a major role in the...
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

A case of amoebic colitis with amoeboma and simultaneous liver abscesses. A diagnosis by colonoscopy.
Authors: Bronswijk M, Van Gool S Abstract A 50-year-old patient was admitted to our department after developing severe abdominal cramps, watery diarrhea and fever, during four days whilst travelling abroad. Imaging identified a mass in the ascending colon with simultaneous liver lesions. Initially a diagnosis of metastatic colorectal cancer was suggested, however colonoscopy showed a large lesion with a central ulcer and surrounding inflammation in the ascending colon. Biopsies confirmed our clinical suspicion of amoebic colitis, complicated by development of an amoeboma and simultaneous liver abscesses. Amoeboma f...
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Calcium polystyrene sulfonate-induced gastrointestinal tract necrosis and perforation.
Authors: Buraphat P, Niyomnaitham S, Pongpaibul A, Maneerattanaporn M PMID: 31950813 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Cystotome assisted stent recanalization : an alternative way of regaining access to occluded metal biliary stents.
Authors: Bronswijk M, Carton S, Christiaens P PMID: 31950814 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Coexistence of ampulla Vater tumor and Castleman's disease: a rare case report.
Authors: Balkaya T, Babayev A, Aydın I, Gür EÖ, Dilek ON PMID: 31950815 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

How will the welfare state cope with welfare diseases such as NASH?
Authors: Vandekerckhove P, Van Damme B, Annemans L PMID: 31950816 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Autoimmune hepatitis in a patient with thymectomy: the benefit of histology and MUM-1 immunostaining.
Authors: Ulpiano Trillig A, Ramoisiaux L, Komuta M, Lanthier N PMID: 31950817 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

A not-so-innocent kiss.
Authors: Busschaert J, Van de Bruaene C, Van Caillie MA, Van Hootegem P PMID: 31950818 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

What happened to my liver lesion (Hepatic Sclerosed Hemangioma)? Let's not forget (radiological) history.
Authors: Renzulli M, Capozzi N, Clemente A, Tovoli F, Cappabianca S, Golfieri R PMID: 31950819 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - January 19, 2020 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Endoscopic submucosal multi-tunnel dissection for large early esophageal cancer lesions.
CONCLUSION: ESMTD is a safe and efficient technique for treating large early esophageal cancer lesions. Grasping the key techniques of this procedure can reduce operating difficulty and shorten the operating time. PMID: 31566321 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

EUS-guided tissue samples for the diagnosis of patients with a thickened gastric wall and prior negative endoscopic biopsies.
CONCLUSION: EUS-FNA/FNB is necessary in patients with a thickened gastric wall and prior negative biopsy on endoscopy. The procedure is safe and has a good diagnostic. PMID: 31566322 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Ulcerative colitis treatment : an insight into daily clinical practice.
Authors: Bossuyt P, Baert F, Coenegrachts JL, De Vos M, Dewit O, Ferrante M, Fontaine F, Mana F, Vandervoort J, Moreels T Abstract BACKGROUND: The natural history of ulcerative colitis (UC) is unpredictable. Factors associated with the need for different types of step-up therapy in UC patients failing on 5-aminosalicylic acid (5-ASA) or corticosteroids are understudied. AIMS: Describe step-up therapy in patients with UC the first year after failing on 5-ASA or corticosteroids. METHODS: A Belgian, multi-center, prospective, non-interventional observational study comprising adult UC patients failing on 5-ASA ...
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Feasibility of endoscopic submucosal dissection for recurrent colorectal tumors after endoscopic mucosal resection.
CONCLUSIONS: Colorectal ESD is feasible for recurrent colorectal lesions after EMR. The procedure is safe and achieves good treatment outcomes with no local recurrence. PMID: 31566324 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Who to screen for hepatitis C? A cost-effectiveness study in Belgium of comprehensive hepatitis C screening in four target groups.
CONCLUSION: A broad screening strategy combined with treatment is likely to be a cost-effective strategy to detect and treat HCV infected patients and diminish the HCV burden in Belgium. PMID: 31566325 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Preoperative biliary drainage in patients performing pancreaticoduodenectomy : guidelines and real-life practice.
CONCLUSIONS: PBD is often performed in patients undergoing PD without a formal indication, mainly due to high bilirubin levels. No increased morbidity/mortality was observed but length of hospital stay was prolonged in patients performing PBD. PMID: 31566326 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

A comparison of the BISAP score and Amylase and BMI (CAB) score versus for predicting severe acute pancreatitis.
CONCLUSION: BISAP is more accurate for predicting the severity of acute pancreatitis than the CAB score. PMID: 31566327 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

On demand pancreatic stenting in chronic pancreatitis might provide good palliation of pain.
CONCLUSIONS: On demand replacement of pancreatic stent is feasible in patients with CP and it might provide a good palliation of CP-related pain. PMID: 31566328 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

The effect of oral polyethylene glycol combined with simethicone for colonoscopy on cecal intubation rate, tolerability and acceptability : a systematic review and meta-analysis.
CONCLUSION: Adjunction of oral simethicone to polyethylene glycol as bowel preparation agent dose not improve cecal intubation rate on colonoscopy,but with better gastrointestinal tolerability and acceptability. PMID: 31566329 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Update on liver transplantation for cholangiocarcinoma : a review of the recent literature.
Authors: Laurent S, Verhelst X, Geerts A, Geboes K, De Man M, Troisi R, Vanlander A, Rogiers X, Berrevoet F, Van Vlierberghe H Abstract Cholangiocarcinoma (CC) represent 3% of all gastrointestinal tumours and can be classified anatomically in 3 types: intrahepatic (ICC), perihilar (PCC) and distal (DCC) cholangiocarcinomas. Resection is the treatment of choice but is only achieved in a few cases (
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

How to diagnose splenic abscesses?
Authors: Nieciecki M, Kozuch M, Czarniecki M, Mlosek RK, Michno A, Olszewski W, Danowska A, Królicki L Abstract Splenic abscess is a rare but potentially fatal entity, occurring mainly in patients with underlying risk factors. Mortality of the disease depends on the time of diagnosis and treatment. Due to low sensitivity and specificity of clinical symptoms and laboratory markers, imaging plays the vital role in the diagnostic work-up. The aim of this article is to give a concise overview of the methods of splenic abscess diagnosis. PMID: 31566331 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

M énétrier's disease : a case of successful treatment using long-acting octreotide.
Ménétrier's disease : a case of successful treatment using long-acting octreotide. Acta Gastroenterol Belg. 2019 Jul-Sep;82(3):429-432 Authors: Nunes G, Barosa R, Patita M, Pinto-Marques P, Gonçalves D, Fonseca C, Alves de Matos A, Fonseca J Abstract The authors describe a 31 years old male, admitted for hematemesis, epigastric pain and lower limb edema. Laboratorial data showed haemoglobin 18.4g/dl, total proteins 2.8g/dl, albumin 1.6g/dl and hipogammaglobulinaemia. 24h urinary proteins were normal. HIV and CMV serology were negative. Upper GI endoscopy revealed markedly enlarged ...
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Survival : a rare outcome in large cell neuroendocrine carcinoma of the gallbladder.
We report the rare outcome of survival at 19 month follow-up and hope to raise awareness about this lesion, its treatment modalities and lend credence to the proposed mechanism of its pathogenesis. PMID: 31566333 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Transluminal removal of a giant fibrovascular polyp of the esophagus.
We present the case of a 42 year old man in whom a giant polyp was removed transorally by a combination of instruments and materials from different disciplines (gastroenterological, surgical and laryngological). PMID: 31566334 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Giant peritoneal loose body : a case report and review of the literature.
We present a case about a 53-year-old man who complained of abdominal pain and constipation. Computed tomography showed a well-described nodular structure of 6cm in size with a central dense core of 0.5cm with compression against the rectosigmoid. The presence of a foreign body was suggested and a diagnostic laparoscopy was performed. Surgery revealed a giant peritoneal loose body measuring 5.5cm in diameter. After the removal, the patient was relieved of his symptoms. Peritoneal loose bodies are usually small and asymptomatic. They are mostly found incidentally during laparotomy. Giant peritoneal loose bodies are a rare e...
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Two cases of peripancreatic cystic lymphangiomas diagnosed by EUS-guided FNA.
Authors: Rosa CJ, Stratton A, Hall N, Laczek J PMID: 31566336 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Cryptosporidiosis in a patient with Crohn's disease under anti-TNF treatment.
Authors: Miranda A, De Musis C, Sgambato D, De Mauro D, Picascia D, Avallone L, Romano L, D'Armiento FP, Romano M PMID: 31566337 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Fatal anaphylaxis of ranitidine injection : have we not learnt the lesson yet?
Authors: Chuah YY, Lee YY, Lin LF, Kuo CJ PMID: 31566338 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Metastases until proven otherwise.
Authors: Gossé S, Driessen A, Op de Beeck B, Francque S PMID: 31566339 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

A rare cause of colic polyp in a patient with ischemic colitis.
Authors: Curraj E, Ntounda R, Van Houte B, Delporte G, Lacremans D PMID: 31566340 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Unexpected newborns in the liver : hemangiomatosis onset after hepatic resection of a giant cavernous hemangioma.
Authors: Renzulli M, Ricciardi D, Clemente A, Tovoli F, Cappabianca S, Golfieri R PMID: 31566341 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Eosinophilic peak counts in eosinophilic esophagitis : a retrospective study.
Authors: Vanstapel A, Vanuytsel T, De Hertogh G Abstract BACKGROUND: The histologic diagnosis of eosinophilic esophagitis (EoE) is based on finding>15 eosinophils/high power field (HPF) on any level within the squamous epithelium of the esophagus. However, this criterion is based on a consensus statement, and controversy remains about the exact number of eosinophils/HPF needed to diagnose EoE. We aimed to determine eosinophilic peak counts in esophageal, gastric, and duodenal biopsies from suspected EoE patients, investigate the correlation between eosinophilic peak counts at different biopsy locations, and dete...
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Necessity of fundoplication and mesh in the repair of the different types of paraesophageal hernia.
CONCLUSION: Laparoscopic PEH repair is a safe and efficacious procedure with no mortality and minimal early morbidity. The surgical repair of PEH should be adjusted to the type of PEH. However, up until now the literature fails to produce clear guidelines on when to perform a gastropexy or Nissen fundoplication and which patients might benefit from a mesh reinforcement. PMID: 31314184 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Endoscopic features, pathological correlates and possible origin of foveolar gastric metaplasia presenting as a duodenal polyp.
Authors: Toussaint C, Libbrecht L, Dano H, Piessevaux H Abstract It has recently been shown that duodenal foveolar gastric metaplasia (FGM) sometimes presents as a polyp. The mechanism by which FGM develops into a polypoid lesion is unknown and it is unclear whether this form of FGM is indistinguishable from other polypoid lesions or whether endoscopists do not recognize it because they are unfamiliar with it. We identified and retrieved archival cases of FGM endoscopically suspicious for adenomatous polyp and examined their pathological, clinical and endoscopic features. Endoscopic features of the 13 identified FG...
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Changes in the patterns and microbiology of spontaneous bacterial peritonitis : analysis of 200 cirrhotic patients.
CONCLUSIONS: Changes in the patterns and microbiology of SBP are evident in our region with increasing prevalence of culture negative SBP, extended spectrum beta-lactamases resistant E.Coli, and increased resistance rate to first line antibiotics. Our data argue for relying on periodic hospital based antibiotic susceptibility data whenever SBP is treated. PMID: 31314186 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

The comparison of the efficacy of diffusion weighted imaging (DWI) sequences with 3 different T2-weighted sequences in the detection of focal liver lesions.
CONCLUSION: Even though the higher lesion detection rates of the DWI sequences were not found to be statistically significant, it was concluded that making the evaluations with the addition of DWI to the imaging protocol would certainly decrease the lesion-missing rate, and it would be wise to utilize the DWI technique in routine liver MR imaging. PMID: 31314187 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Effects of entecavir, tenofovir and telbivudine treatment on renal functions in chronic hepatitis B patients.
Authors: Kara AV, Yıldırım Y, Ozcicek F, Aldemir MN, Arslan Y, Bayan K, Çelen MK Abstract BACKGROUND AND STUDY AIMS: The aim of this study was to enlighten the controversy about the renal safety of entecavir, tenofovir, and telbivudine treatments in chronic hepatitis B (CHB) patients by comparing these treatments in real-world conditions. PATIENTS AND METHODS: We retrospectively enrolled 104 treatment-naive patients with CHB monoinfection into our study. Patients were treated with entecavir monotherapy (n=38), tenofovir monotherapy (n=35), or telbivudine monotherapy (n=31). We then compared and statis...
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

The efficacy of a computer alert programme for increasing HBV screening rates before starting immunosuppressive therapy.
Authors: Köksal AS, Toka B, Eminler AT, Hacıbekiroğlu I, Sunu C, Uslan MI, Karabay O, Parlak E Abstract BACKGROUND AND AIM: Hepatitis B Virus (HBV) screening before starting immunosuppressive treatment is of vital importance in order to prevent HBV reactivation and its associated clinical consequences. Despite all recommendations by international organizations, screening rates are far below desired. The aim of this study was to assess the efficacy of a computer alert programme 'HBVision' for increasing HBV screening rates. MATERIAL AND METHODS: 'HBVision' identifies patients at risk of HBV reactivation b...
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Relationship between nucleotide-binding oligomerization domain-containing protein 2 variants and severity of acute pancreatitis.
Authors: Harputluoglu MMM, Ozbek M, Demirel U, Otlu B, Yener O, Gursoy NC, Tikici D, Erdogan MA, Caliskan AR, Dertli R Abstract BACKGROUND AND AIM: Intestinal barrier dysfunction has been implicated in the development of infectious complications of acute pancreatitis. Nucleotide-Binding Oligomerization DomainContaining Protein 2 (NOD2) plays an important role in the proper functioning of intestinal defense mechanisms. Here, we investigated the frequency of NOD2 variants in patients with mild and severe acute pancreatitis. MATERIALS AND METHODS: Groups 1, 2 and 3 comprised healthy participants and patients with ...
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Systematic review and meta-analysis : diagnostic accuracy of faecal immunochemical testing for haemoglobin (FIT) in detecting colorectal cancer for both symptomatic and screening population.
CONCLUSION: For the detection of CRC within the screening population, FIT has high specificity and sensitivity. In the symptomatic group, FIT's high sensitivity (90%) supports its role as a triage test to guide the selection of patients who require urgent lower gastrointestinal tract evaluation. PMID: 31314191 [PubMed - in process] (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - July 19, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research