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Cushing's syndrome of the orbit: congestive orbitopathy and optic neuropathy associated with steroids
Orbit. 2023 Oct 19:1-4. doi: 10.1080/01676830.2023.2268158. Online ahead of print.ABSTRACTA 56-year-old female with a history of chronic systemic steroid use for asthma control displayed orbital congestion, exophthalmos, a mild abduction deficit, and optic neuropathy. Laboratory workup was unrevealing. Neuroimaging showed increased orbital fat compartments, though the orbital fat was unremarkable on biopsy. The patient was diagnosed with iatrogenic Cushing's syndrome of the orbit and underwent orbital decompression. Early published literature declared this orbitopathy benign. However, newer cases describe more pathologic c...
Source: Orbit - October 19, 2023 Category: Opthalmology Authors: Leroy Ekeh Hanan Ibrahim Firas Askar Alireza Meysami Brittany A Simmons Source Type: research

Cushing's syndrome presenting as non ‐atherosclerotic myocardial infarction and heart failure
AbstractCushing's syndrome is a rare cause of myocardial infarction and heart failure. Herein, we report a female patient who presented acute myocardial infarction and heart failure with reduced ejection fraction. The patient was found to have hypercortisolism secondary to adrenocortical adenoma and responded well to therapy. This case underlines the effects of hypercortisolism on the cardiovascular system. The clinical presentation of this patient is unique because non-atherosclerotic myocardial infarction is rarely reported in Cushing's syndrome patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 19, 2023 Category: Cardiology Authors: Yanming Li, Songqing He, Jing Feng, Sai Ma, Lei Wang Tags: Case Report Source Type: research

Pediatric and Adolescent Ectopic Cushing's Syndrome: Systematic Review
CONCLUSIONS: Etiological profile of pediatric and adolescent EAS is distinct from that of adults. Bronchial NETs have the best long-term survival whereas distant metastasis and tumor size predict poor survival.PMID:37801647 | DOI:10.1093/ejendo/lvad133 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - October 6, 2023 Category: Endocrinology Authors: Chethan Yami Channaiah Manjiri Karlekar Vijaya Sarathi Anurag Ranjan Lila Shruthi Ravindra Padma Vikram Badhe Gaurav Malhotra Saba Samad Memon Virendra Ashokrao Patil C S Pramesh Tushar Bandgar Source Type: research