Calcium homeostasis pathologies in hyperparathyroidism: nephrologic and endocrinologic points of view
Ann Endocrinol (Paris). 2022 May 19:S0003-4266(22)00083-X. doi: 10.1016/j.ando.2022.05.003. Online ahead of print.ABSTRACTParathyroid hormone (PTH) is a hypercalcemic hormone acting on kidneys, bone and intestine. PTH promotes calcium release from the bone, renal calcium reabsorption and phosphate excretion, and conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D-3. Hyperparathyroidism consists in PTH elevation, which may be adapted (secondary hyperparathyroidism) or non-adapted to calcemia levels (primary hyperparathyroidism, familial hypercalcemia/hypocalciuria, tertiary hyperparathyroidism). Primary hyperparath...
Source: Annales d'Endocrinologie - May 22, 2022 Category: Endocrinology Authors: Sandrine Lemoine Lucile Figueres Justine Bacchetta Samuel Frey Laurence Dubourg Source Type: research

Calcium homeostasis pathologies in hyperparathyroidism: nephrologic and endocrinologic points of view
Ann Endocrinol (Paris). 2022 May 19:S0003-4266(22)00083-X. doi: 10.1016/j.ando.2022.05.003. Online ahead of print.ABSTRACTParathyroid hormone (PTH) is a hypercalcemic hormone acting on kidneys, bone and intestine. PTH promotes calcium release from the bone, renal calcium reabsorption and phosphate excretion, and conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D-3. Hyperparathyroidism consists in PTH elevation, which may be adapted (secondary hyperparathyroidism) or non-adapted to calcemia levels (primary hyperparathyroidism, familial hypercalcemia/hypocalciuria, tertiary hyperparathyroidism). Primary hyperparath...
Source: Annales d'Endocrinologie - May 22, 2022 Category: Endocrinology Authors: Sandrine Lemoine Lucile Figueres Justine Bacchetta Samuel Frey Laurence Dubourg Source Type: research

Calcium homeostasis pathologies in hyperparathyroidism: nephrologic and endocrinologic points of view
Ann Endocrinol (Paris). 2022 May 19:S0003-4266(22)00083-X. doi: 10.1016/j.ando.2022.05.003. Online ahead of print.ABSTRACTParathyroid hormone (PTH) is a hypercalcemic hormone acting on kidneys, bone and intestine. PTH promotes calcium release from the bone, renal calcium reabsorption and phosphate excretion, and conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D-3. Hyperparathyroidism consists in PTH elevation, which may be adapted (secondary hyperparathyroidism) or non-adapted to calcemia levels (primary hyperparathyroidism, familial hypercalcemia/hypocalciuria, tertiary hyperparathyroidism). Primary hyperparath...
Source: Annales d'Endocrinologie - May 22, 2022 Category: Endocrinology Authors: Sandrine Lemoine Lucile Figueres Justine Bacchetta Samuel Frey Laurence Dubourg Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Brain metastasis from calcitonin-negative medullary thyroid carcinoma
CONCLUSIONS: We describe a rare case of "calcitonin-negative" MTC with brain metastasis. The pathophysiology underlying normal serum levels of calcitonin in MTC is still not clearly understood. The lack of effective serum biomarkers for these patients makes diagnosis and treatment challenging.PMID:35537523 | DOI:10.1016/j.ando.2022.04.015 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 10, 2022 Category: Endocrinology Authors: Patr ícia Ferreira Baptista Liliana Cec ília Martins Fonseca Andr é Filipe Couto de Carvalho Sara Neves Vieira da Silva Cl áudia Raquel Oliveira Freitas Source Type: research

Fertility in men with Klinefelter's syndrome
In conclusion, further studies are necessary to determine the interest of new markers to predict the chance of sperm retrieval, taking into account age, hormonal therapy.PMID:35526602 | DOI:10.1016/j.ando.2022.05.002 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - May 8, 2022 Category: Endocrinology Authors: Ingrid Plotton Lucie Renault Marion Lapoirie Damien Sanlaville Ren é Ecochard Sandrine Giscard d'Estaing Beatrice Cuzin Frederique Dijoud Bruno Salle Beatrice Herve Lejeune Source Type: research

Thyroid pathology and female fertility: myth or reality?
Ann Endocrinol (Paris). 2022 May 5:S0003-4266(22)00064-6. doi: 10.1016/j.ando.2022.05.001. Online ahead of print.ABSTRACTThe relationship between thyroid state and female fertility is an area of particular interest for both clinicians and researchers worldwide. This is partially due to the increasing prevalence of infertility and to the understanding of its complex and multifactorial aetiology. Studies conducted in variable forms of female infertility (eg, recurrent miscarriages or polycystic ovarian syndrome) together with the world-wide rising use of assisted reproduction technologies (ART) contributed the uncovering of ...
Source: Annales d'Endocrinologie - May 8, 2022 Category: Endocrinology Authors: Guia Vannucchi Luca Persani Laura Fugazzola Source Type: research