Predicting the intention to receive the COVID-19 booster vaccine based on the health belief model
Acta Psychol (Amst). 2024 Apr 16;246:104254. doi: 10.1016/j.actpsy.2024.104254. Online ahead of print.ABSTRACTCOVID-19 vaccine boosters are recommended because the protection provided by previous doses eventually decreases, posing a threat to immunity. Some people, however, remain hesitant or unwilling to get vaccinated. The present study sought to investigate factors associated with the intention to receive the COVID-19 booster vaccine based on (1) the constructs of the Health Belief Model, and (2) trust in healthcare workers and science. A sample of 165 adults with two doses of the COVID-19 vaccine were recruited using c...
Source: Acta Psychologica - April 17, 2024 Category: Psychiatry & Psychology Authors: Milja Ventonen Nicola Douglas-Smith Bianca Hatin Source Type: research

Acute onset of constrictive pericarditis due to acute myelomonocytic leukemia: A case and literature review
Intern Med. 2024 Apr 16. doi: 10.2169/internalmedicine.3505-24. Online ahead of print.ABSTRACTWe herein present a fatal case of constrictive pericarditis (CP) due to acute myelomonocytic leukemia (AMML) in a patient who initially complained of an acute onset of chest pain two days after COVID-19 vaccination. An autopsy revealed pericardial infiltration of leukemic cells. CP is rarely associated with leukemia and only 14 cases have been reported in the literature. The etiology of CP in previous reports included leukemic infiltration, graft-versus-host disease, drug-induced, post-radiation, autoimmune, and otherwise unidenti...
Source: Internal Medicine - April 17, 2024 Category: Internal Medicine Authors: Naoki Kosaka Takanori Uchiyama Masahiro Onozawa Jun Nagai Jiro Koya Suguru Ishizaka Toshiyuki Nagai Yohei Ikebe Kenjiro Kato Zen-Ichi Tanei Jun Sakakibara-Konishi Yuta Hasegawa Hiroyuki Ohigashi Hideki Goto Daigo Hashimoto Hideki Ujiie Satoshi Hirano Sato Source Type: research

Incidence of SARS-CoV-2 Seropositivity in Pediatric Healthcare Workers Prior to Widespread Vaccination: A Five-month Longitudinal Cohort Study
Understanding the prevalence and incidence of SARS-CoV-2 infection among frontline healthcare workers is important to inform health policy and strategy. In the early stages of the COVID-19 pandemic, children were thought to be at low risk for infection, suggesting minimal risk of work-acquired SARS-CoV-2 infection in pediatric healthcare workers (pHCWs). This is due to early hypotheses that children were not affected by and did not spread SARS-CoV-2 to the degree that was seen among adult patients and their caregivers [1]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 17, 2024 Category: Infectious Diseases Authors: Mark Griffiths, Dunia Hatabah, Patrick Sullivan, Grace Mantus, Travis Sanchez, Maria Zlotorzynska, Stacy Heilman, Andres Camacho-Gonzalez, Deborah Leake, Rawan Korman, Mimi Le, Mehul Suthara, Jens Wrammert, Miriam B. Vos, Claudia R. Morris Source Type: research

IJERPH, Vol. 21, Pages 491: Optimizing the Selection of Mass Vaccination Sites: Access and Equity Consideration
all In the early phases of the COVID-19 pandemic, vaccine accessibility was limited, impacting large metropolitan areas such as Los Angeles County, which has over 10 million residents but only nine initial vaccination sites, which resulted in people experiencing long travel times to get vaccinated. We developed a mixed-integer linear model to optimize site selection, considering equitable access for vulnerable populations. Analyzing 277 zip codes between December 2020 and May 2021, our model incorporated factors such as car ownership, ethnic group disease vulnerability, and the Healthy Places Index, alongside travel ti...
Source: International Journal of Environmental Research and Public Health - April 17, 2024 Category: Environmental Health Authors: Basim Aljohani Randolph Hall Tags: Article Source Type: research

Translation and trans-cultural adaptation to the Malay version of the COVID-19 vaccine hesitancy questionnaire among healthcare workers in Malaysia
ConclusionsThe questionnaire was valid and reliable for use in the Malay language. (Source: PLoS One)
Source: PLoS One - April 17, 2024 Category: Biomedical Science Authors: Siti Nur Aisyah Zaid Source Type: research

COVID-19 vaccine acceptance in the general population and under-resourced communities from high-income countries: realist review
Conclusion Our review emphasises the importance of realist reviews for assessing vaccine acceptance. Limited real-world evidence about vaccine uptake among under-resourced communities in high-income countries is a call to context-specific actions and reporting. (Source: BMJ Open)
Source: BMJ Open - April 17, 2024 Category: General Medicine Authors: Gonzalez-Jaramillo, N., Abbühl, D., Roa-Diaz, Z. M., Kobler-Betancourt, C., Frahsa, A. Tags: Open access, Public health Source Type: research

Potential impact of annual vaccination with reformulated COVID-19 vaccines: Lessons from the US COVID-19 scenario modeling hub
ConclusionsCOVID-19 is projected to be a significant public health threat over the coming 2 years. Broad vaccination has the potential to substantially reduce the burden of this disease, saving tens of thousands of lives each year. (Source: PLoS Medicine)
Source: PLoS Medicine - April 17, 2024 Category: Internal Medicine Authors: Sung-mok Jung Source Type: research

Plans to expand African vaccine production face steep hurdles
In March 2022, when the pandemic was still raging, the messenger RNA (mRNA) company Moderna announced it would build a $500 million plant in Kenya to manufacture half a billion doses of its COVID-19 vaccine annually. “ This is major ,” Kenyan President William Ruto said at the time. The plant would help reduce Africa’s dependence on vaccines produced elsewhere, Ruto said—a situation that had turned disastrous during the pandemic—and bring economic benefits as well. But Moderna may never break ground on the Kenya factory. On 11 April, the company said it had “paused its efforts” becau...
Source: Science of Aging Knowledge Environment - April 16, 2024 Category: Geriatrics Source Type: research

Recent advances in immunotherapies against infectious diseases
Immunother Adv. 2020 Nov 25;1(1):ltaa007. doi: 10.1093/immadv/ltaa007. eCollection 2021 Jan.ABSTRACTImmunotherapies are disease management strategies that target or manipulate components of the immune system. Infectious diseases pose a significant threat to human health as evidenced by countries continuing to grapple with several emerging and re-emerging diseases, the most recent global health threat being the SARS-CoV2 pandemic. As such, various immunotherapeutic approaches are increasingly being investigated as alternative therapies for infectious diseases, resulting in significant advances towards the uncovering of path...
Source: Cancer Control - April 16, 2024 Category: Cancer & Oncology Authors: Dharanidharan Ramamurthy Trishana Nundalall Sanele Cingo Neelakshi Mungra Maryam Karaan Krupa Naran Stefan Barth Source Type: research

Review of COVID-19 Therapeutics by Mechanism: From Discovery to Approval
J Korean Med Sci. 2024 Apr 15;39(14):e134. doi: 10.3346/jkms.2024.39.e134.ABSTRACTThe global research and pharmaceutical community rapidly mobilized to develop treatments for coronavirus disease 2019 (COVID-19). Existing treatments have been repurposed and new drugs have emerged. Here we summarize mechanisms and clinical trials of COVID-19 therapeutics approved or in development. Two reviewers, working independently, reviewed published data for approved COVID-19 vaccines and drugs, as well as developmental pipelines, using databases from the following organizations: United States Food and Drug Administration (US-FDA), Euro...
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Hee Sun Choi A Young Choi Jeffrey B Kopp Cheryl A Winkler Sung Kweon Cho Source Type: research

Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination
CONCLUSION: Receipt of an mRNA COVID-19 vaccine during pregnancy was not associated with an increased risk of adverse pregnancy outcomes; this information will be helpful for patients and clinicians when considering COVID-19 vaccination in pregnancy.PMID:38626447 | DOI:10.1097/AOG.0000000000005583 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - April 16, 2024 Category: OBGYN Authors: Kimberly K Vesco Anna E Denoble Heather S Lipkind Elyse O Kharbanda Malini B DeSilva Matthew F Daley Darios Getahun Ousseny Zerbo Allison L Naleway Lisa Jackson Joshua T B Williams Thomas G Boyce Candace C Fuller Eric S Weintraub Gabriela Vazquez-Benitez Source Type: research

Clinical and Imaging Characteristics of SARS-CoV-2 Breakthrough Infection in Hospitalized Immunocompromised Patients
CONCLUSION: Immunocompromised patients with COVID-19 breakthrough infection showed an increased risk of severe clinical outcome, severe pneumonia based on chest radiographs, and typical CT pneumonia. In particular, patients status post solid organ transplantation was specifically found to be associated with a higher risk of all three outcomes than hospitalized immunocompetent patients.PMID:38627873 | DOI:10.3348/kjr.2023.0992 (Source: Korean J Radiol)
Source: Korean J Radiol - April 16, 2024 Category: Radiology Authors: Jong Eun Lee Jinwoo Kim Minhee Hwang Yun-Hyeon Kim Myung Jin Chung Won Gi Jeong Yeon Joo Jeong Source Type: research

Review of COVID-19 Therapeutics by Mechanism: From Discovery to Approval
J Korean Med Sci. 2024 Apr 15;39(14):e134. doi: 10.3346/jkms.2024.39.e134.ABSTRACTThe global research and pharmaceutical community rapidly mobilized to develop treatments for coronavirus disease 2019 (COVID-19). Existing treatments have been repurposed and new drugs have emerged. Here we summarize mechanisms and clinical trials of COVID-19 therapeutics approved or in development. Two reviewers, working independently, reviewed published data for approved COVID-19 vaccines and drugs, as well as developmental pipelines, using databases from the following organizations: United States Food and Drug Administration (US-FDA), Euro...
Source: Journal of Korean Medical Science - April 16, 2024 Category: Biomedical Science Authors: Hee Sun Choi A Young Choi Jeffrey B Kopp Cheryl A Winkler Sung Kweon Cho Source Type: research

Clinical and Imaging Characteristics of SARS-CoV-2 Breakthrough Infection in Hospitalized Immunocompromised Patients
CONCLUSION: Immunocompromised patients with COVID-19 breakthrough infection showed an increased risk of severe clinical outcome, severe pneumonia based on chest radiographs, and typical CT pneumonia. In particular, patients status post solid organ transplantation was specifically found to be associated with a higher risk of all three outcomes than hospitalized immunocompetent patients.PMID:38627873 | DOI:10.3348/kjr.2023.0992 (Source: Korean Journal of Radiology)
Source: Korean Journal of Radiology - April 16, 2024 Category: Radiology Authors: Jong Eun Lee Jinwoo Kim Minhee Hwang Yun-Hyeon Kim Myung Jin Chung Won Gi Jeong Yeon Joo Jeong Source Type: research