Durability of Original Monovalent mRNA Vaccine Effectiveness Against COVID-19 Omicron-Associated Hospitalization in Children and Adolescents - United States, 2021-2023
MMWR Morb Mortal Wkly Rep. 2024 Apr 18;73(15):330-338. doi: 10.15585/mmwr.mm7315a2.ABSTRACTPediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U.S. children and adolescen...
Source: MMWR Morb Mortal Wkl... - April 18, 2024 Category: Epidemiology Authors: Laura D Zambrano Margaret M Newhams Regina M Simeone Amanda B Payne Michael Wu Amber O Orzel-Lockwood Natasha B Halasa Jemima M Calixte Pia S Pannaraj Kanokporn Mongkolrattanothai Julie A Boom Leila C Sahni Satoshi Kamidani Kathleen Chiotos Melissa A Came Source Type: research

COVID-19 Vaccination Coverage, and Rates of SARS-CoV-2 Infection and COVID-19-Associated Hospitalization Among Residents in Nursing Homes - National Healthcare Safety Network, United States, October 2023-February 2024
MMWR Morb Mortal Wkly Rep. 2024 Apr 18;73(15):339-344. doi: 10.15585/mmwr.mm7315a3.ABSTRACTNursing home residents are at increased risk for developing severe COVID-19. Nursing homes report weekly facility-level data on SARS-CoV-2 infections, COVID-19-associated hospitalizations, and COVID-19 vaccination coverage among residents to CDC's National Healthcare Safety Network. This analysis describes rates of incident SARS-CoV-2 infection, rates of incident COVID-19-associated hospitalization, and COVID-19 vaccination coverage during October 16, 2023-February 11, 2024. Weekly rates of SARS-CoV-2 infection ranged from 61.4 to 13...
Source: MMWR Morb Mortal Wkl... - April 18, 2024 Category: Epidemiology Authors: David Franklin Kira Barbre Theresa A Rowe Hannah E Reses Jason Massey Lu Meng Philip Dollard Heather Dubendris Molly Stillions Lindsay Robinson Jacques W Clerville Kara Jacobs Slifka Andrea Benin Jeneita M Bell Source Type: research

Extracorporeal membrane oxygenation (ECMO) during aplasia: A bridge towards myopericarditis recovery after autologous hematopoietic stem cell transplant for systemic sclerosis and recent Coronarovirus disease (COVID-19) vaccination
This report illustrates, for the first time to our knowledge, that ECMO can be indicated despite aplasia during aHSCT and successfully used as a bridge towards heart function recovery in highly selected and fragile AD patients. We review the factors that may contribute to endothelial and myocardial stunning and acute reversible cardiac failure in SSc and aggravate intrinsic endothelial injury during the aHSCT procedure. These classically include: cyclophosphamide drug toxicity, viral infections and autoimmune activation with disease flair per se. In the COVID-19 pandemic times, acute myocarditis due to recent viral infecti...
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Carlotta Cacciatore Mathilde Baudet Estelle Jean Simona Presente Marylou Para Romain Sonneville Dimitri Arangalage Nassim Ait Abdallah Flore Sicre de Fontbrune Pedro Henrique Prata Benjamin Crichi Baptiste Hervier Nathalie Parquet Gilles Soulat Elie Mouss Source Type: research

Exploring COVID-19 vaccine uptake and hesitancy among vulnerable populations in inner city Vancouver, Canada: Insights into characteristics and clinical outcomes
In this study, we investigated vaccination rates and variables as facilitators or barriers to COVID-19 vaccination among vulnerable populations living in Vancouver's inner-city residents. On a weekly basis, a team (including health care providers [HCPs] and support staff) conducts a Community Pop-up Clinic (CPC) event at single room occupancy dwellings in Vancouver's inner city to provide COVID-19 vaccine and/or related information. Participants also completed a survey about their COVID-19 vaccination status and COVID knowledge, including knowledge about COVID vaccination. We collected data from 892 CPC participants betwee...
Source: Vaccine - April 18, 2024 Category: Allergy & Immunology Authors: Saina Beitari Shana Yi Shawn Sharma Rossitta Yung Brian Conway Source Type: research

The Effect of Vaccination with Pfizer-BioNTech or CoronaVac on Disease Prognosis Among Hospitalized COVID-19 Patients
CONCLUSION: Among the inpatients with COVID-19, the predictors for mortality were being unvaccinated, older age, cancer, chronic kidney disease, and cardiovascular diseases. Among the vaccinated inpatients, having two doses of the Pfizer-BioNTech vaccine was the only effective protective measure against mortality, and two doses of the CoronaVac vaccine had no significant effect in preventing fatality.PMID:38633010 | PMC:PMC10985826 | DOI:10.36519/idcm.2023.226 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 18, 2024 Category: Cancer & Oncology Authors: Mustafa G üldan Sena Tu ğana Ateş Sebile Sar ıoğlu Sarp Suyabatmaz Pelin İrkören S üda Tekin Mahir Kapmaz Şiran Keske Önder Ergönül Source Type: research

Durability of Original Monovalent mRNA Vaccine Effectiveness Against COVID-19 Omicron-Associated Hospitalization in Children and Adolescents - United States, 2021-2023
MMWR Morb Mortal Wkly Rep. 2024 Apr 18;73(15):330-338. doi: 10.15585/mmwr.mm7315a2.ABSTRACTPediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U.S. children and adolescen...
Source: MMWR Morb Mortal Wkl... - April 18, 2024 Category: Epidemiology Authors: Laura D Zambrano Margaret M Newhams Regina M Simeone Amanda B Payne Michael Wu Amber O Orzel-Lockwood Natasha B Halasa Jemima M Calixte Pia S Pannaraj Kanokporn Mongkolrattanothai Julie A Boom Leila C Sahni Satoshi Kamidani Kathleen Chiotos Melissa A Came Source Type: research

COVID-19 Vaccination Coverage, and Rates of SARS-CoV-2 Infection and COVID-19-Associated Hospitalization Among Residents in Nursing Homes - National Healthcare Safety Network, United States, October 2023-February 2024
MMWR Morb Mortal Wkly Rep. 2024 Apr 18;73(15):339-344. doi: 10.15585/mmwr.mm7315a3.ABSTRACTNursing home residents are at increased risk for developing severe COVID-19. Nursing homes report weekly facility-level data on SARS-CoV-2 infections, COVID-19-associated hospitalizations, and COVID-19 vaccination coverage among residents to CDC's National Healthcare Safety Network. This analysis describes rates of incident SARS-CoV-2 infection, rates of incident COVID-19-associated hospitalization, and COVID-19 vaccination coverage during October 16, 2023-February 11, 2024. Weekly rates of SARS-CoV-2 infection ranged from 61.4 to 13...
Source: MMWR Morb Mortal Wkl... - April 18, 2024 Category: Epidemiology Authors: David Franklin Kira Barbre Theresa A Rowe Hannah E Reses Jason Massey Lu Meng Philip Dollard Heather Dubendris Molly Stillions Lindsay Robinson Jacques W Clerville Kara Jacobs Slifka Andrea Benin Jeneita M Bell Source Type: research

The relationship between benevolence and attitudes towards preventive behaviour during the COVID-19 pandemic in Sweden
ConclusionFurther, there was a significant correlation between altruistic motives and compliance with recommendations, including the view on taking the vaccine. Our findings add to the concept that prosocial orientation during the COVID-19 pandemic increases compliance with preventive behaviour. (Source: Journal of Public Health)
Source: Journal of Public Health - April 18, 2024 Category: Health Management Source Type: research

Influences of race, ethnicity, and other social factors on coronavirus disease 2019 vaccination uptake among patients undergoing in vitro fertilization
Patients undergoing IVF at a university-based clinic during 2020 to 2021 who self-identified as Black, Hispanic, or Other race were less likely to become vaccinated against COVID-19, compared with White patients. (Source: Fertility and Sterility)
Source: Fertility and Sterility - April 18, 2024 Category: Reproduction Medicine Authors: Leigh A. Humphries, Jeremy Applebaum, Florencia G. Polite, Elizabeth Kravitz, Clarisa R. Gracia, Dara S. Berger Tags: Research letter Source Type: research

Analysis of causal relations between vaccine hesitancy for COVID-19 vaccines and ideological orientations in Brazil
This article presents a causal inference analysis of vaccine hesitancy for Coronavirus disease 2019 (COVID-19) vaccines based on socio-demographic data obtained via questionnaires applied to a sample of the Brazilian population. This data includes the respondents' political preferences, age group, education, salary range, country region, sex, believing fake news, vaccine confidence, and intention to get the COVID-19 vaccine. The research created a causal graph using these variables, seeking to answer questions about the probability of people getting vaccinated. The results of this research corroborate findings observed in ...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Eanes Torres Pereira Sylvia Iasulaitis Bruno Cardoso Greco Source Type: research

Avoidable COVID-19-related deaths and hospitalizations in Brazil, 2020-2023
CONCLUSIONS: PLPE reduction in 2023 was likely caused by low vaccine uptake. The disease burden could have been much lower had the vaccination started earlier and had the vaccine uptake not dropped so sharply in 2023.PMID:38631953 | DOI:10.1016/j.vaccine.2024.04.041 (Source: Vaccine)
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Emil Kupek Source Type: research

Overview of U.S. COVID-19 vaccine safety surveillance systems
This report describes the U.S. government's COVID-19 vaccine safety monitoring systems and programs used by the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the Department of Defense, the Department of Veterans Affairs, and the Indian Health Service. Using the adverse event of myocarditis following mRNA COVID-19 vaccination as a model, we demonstrate how the multiple, complementary monitoring systems worked to rapidly detect, assess, and verify a vaccine safety signal. In addition, longer-term follow-up was conducted to evaluate the recovery status of myocarditis cases following vaccin...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Julianne Gee Tom T Shimabukuro John R Su David Shay Margaret Ryan Sridhar V Basavaraju Karen R Broder Matthew Clark C Buddy Creech Francesca Cunningham Kristin Goddard Harrison Guy Kathryn M Edwards Richard Forshee Tanya Hamburger Anne M Hause Nicola P Kl Source Type: research

COVID-19 vaccination communication: Effects of vaccine conspiracy beliefs and message framing among black and white participants
CONCLUSION: It is crucial for health officials to work to find effective media message strategies to combat COVID-19 vaccine conspiracy theories and misinformation. Furthermore, this study supports the significance of health organizations' ongoing efforts to tailor public health messaging to specific racial groups, as evidenced by considerable variations in perceptions among Black and White Americans.PMID:38631951 | DOI:10.1016/j.vaccine.2024.04.001 (Source: Vaccine)
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Namyeon Lee Yoorim Hong Ciera E Kirkpatrick Sisi Hu Sungkyoung Lee Amanda Hinnant Source Type: research

Understanding the views of adult migrants around catch-up vaccination for missed routine immunisations to define strategies to improve coverage: A UK in-depth interview study
CONCLUSIONS: The major barrier to adult catch-up vaccination for missed routine immunisations and doses in migrant communities in the UK is the limited opportunities, recommendations or tailored vaccination information presented to migrants by health services. This could be improved with financial incentives for provision of catch-up vaccination in UK primary care, alongside training of healthcare professionals to support catch-up immunisation and raise awareness of existing guidelines. It will also be essential to address root causes of mistrust around vaccination, where it exists among migrants, by working closely with c...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Anna Deal Alison F Crawshaw Maha Salloum Sally E Hayward Jessica Carter Felicity Knights Farah Seedat Oumnia Bouaddi Nuria Sanchez-Clemente Laura Muzinga Lutumba Lusau Mimi Kitoko Sarah Nkembi Caroline Hickey Sandra Mounier-Jack Azeem Majeed Sally Hargrea Source Type: research

SARS-CoV-2 Infection, Hospitalization, and Associated Factors Among People Living With HIV in Southeastern China From December 2022 to February 2023: Cross-Sectional Survey
CONCLUSIONS: After the ease of prevention and control measures in China, we observed a high SARS-CoV-2 infection rate but a low hospitalization rate. General risk factors, such as higher age and vaccination status, and HIV-related parameters, such as the latest CD4 cell count and HIV viral load, were associated with SARS-CoV-2 infection and hospitalization. A booster vaccination campaign for booster doses should be considered among people living with HIV in confronting possible COVID-19 epidemic emergencies in the near future.PMID:38630534 | DOI:10.2196/51449 (Source: Cancer Control)
Source: Cancer Control - April 17, 2024 Category: Cancer & Oncology Authors: Wei Cheng Yun Xu Haibo Jiang Jun Li Zhigang Hou Haibin Meng Wei Wang Chengliang Chai Jianmin Jiang Source Type: research