Attributes and Predictors of Opinion Leaders on Twitter: COVID-19 Childhood Vaccination Campaign
. (Source: Health Communication)
Source: Health Communication - April 24, 2024 Category: Health Management Authors: Huai-yu ChenNadia A. SesayDepartment of Communication, University of Kentucky Source Type: research
The Impact of Expert Opinions in COVID-19 News Coverage on Vaccination During the Fifth Outbreak in Hong Kong: A Time Series Analysis
. (Source: Health Communication)
Source: Health Communication - April 24, 2024 Category: Health Management Authors: Yiqian GaoJoseph Tak-Fai LauQingpeng ZhangWai-Kit MingFei ShenYi-Hui Christine HuangLi Crystal Jianga Department of Media and Communication, City University of Hong Kongb The Jockey Club School of Public Health and Primary Care, The Chinese University of Source Type: research
Viruses, Vol. 16, Pages 665: Exploring the Antiviral Potential of Esters of Cinnamic Acids with Quercetin
o Manzin
Giuseppina Sanna
Severe acute respiratory syndrome-related Coronavirus 2 (SARS-CoV-2) has infected more than 762 million people to date and has caused approximately 7 million deaths all around the world, involving more than 187 countries. Although currently available vaccines show high efficacy in preventing severe respiratory complications in infected patients, the high number of mutations in the S proteins of the current variants is responsible for the high level of immune evasion and transmissibility of the virus and the reduced effectiveness of acquired immunity. In this scenario, the development of safe...
Source: Viruses - April 24, 2024 Category: Virology Authors: Valeria Manca Annalisa Chianese Vanessa Palmas Federica Etzi Carla Zannella Davide Moi Francesco Secci Gabriele Serreli Giorgia Sarais Maria Vittoria Morone Massimiliano Galdiero Valentina Onnis Aldo Manzin Giuseppina Sanna Tags: Article Source Type: research
Viruses, Vol. 16, Pages 661: T-Cell Responses to COVID-19 Vaccines and Breakthrough Infection in People Living with HIV Receiving Antiretroviral Therapy
rco
Malcolm Hedgcock
Cecilia T. Costiniuk
Mark Hull
Marianne Harris
Marc G. Romney
Julio S. G. Montaner
Zabrina L. Brumme
Mark A. Brockman
People living with HIV (PLWH) can exhibit impaired immune responses to vaccines. Accumulating evidence indicates that PLWH, particularly those receiving antiretroviral therapy, mount strong antibody responses to COVID-19 vaccines, but fewer studies have examined cellular immune responses to the vaccinations. Here, we used an activation-induced marker (AIM) assay to quantify SARS-CoV-2 spike-specific CD4+ and CD8+ T cells generated by two and three doses of COVID-19 v...
Source: Viruses - April 24, 2024 Category: Virology Authors: Sneha Datwani Rebecca Kalikawe Rachel Waterworth Francis M. Mwimanzi Richard Liang Yurou Sang Hope R. Lapointe Peter K. Cheung Fredrick Harrison Omondi Maggie C. Duncan Evan Barad Sarah Speckmaier Nadia Moran-Garcia Mari L. DeMarco Malcolm Hedgcock Cecili Tags: Article Source Type: research
Viruses, Vol. 16, Pages 659: Design and Application of Biosafe Coronavirus Engineering Systems without Virulence
ingxin Ma
In the last twenty years, three deadly zoonotic coronaviruses (CoVs)—namely, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and SARS-CoV-2—have emerged. They are considered highly pathogenic for humans, particularly SARS-CoV-2, which caused the 2019 CoV disease pandemic (COVID-19), endangering the lives and health of people globally and causing unpredictable economic losses. Experiments on wild-type viruses require biosafety level 3 or 4 laboratories (BSL-3 or BSL-4), which significantly hinders basic virological r...
Source: Viruses - April 24, 2024 Category: Virology Authors: Guoqiang Wu Qiaoyu Li Junbiao Dai Guobin Mao Yingxin Ma Tags: Review Source Type: research
Determination of optimum levels of binding antibody units (BAU) of new quantitative chemiluminescent immuno-assay (CLIA) in COVID-19 vaccinated volunteer blood donors
This study was undertaken to determine optimum levels of binding antibody units (BAU/ml) in new quantitative chemiluminescent assay (CLIA) that corresponded to neutralizing potential (30% inhibition) of sVNT assay. Methods: Ninety-one blood samples were analyzed by CLIA and sVNT assays. Test samples (n=75) were collected from blood donors post-2nd vaccination dose, while control samples (n=16) were archived pre-COVID donor samples. (Source: Transfusion and Apheresis Science)
Source: Transfusion and Apheresis Science - April 24, 2024 Category: Hematology Authors: Aseem Kumar Tiwari, Geet Aggarwal, Pratibha Kale, Neeti Yadav, Virendra Kumar, Gargi Singh, K. Cheirmaraj, K. Krishnan Source Type: research
The contributions of vaccination and natural infection to the production of neutralizing antibodies against the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) prototype strain and variants
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a novel coronavirus responsible for the coronavirus disease 2019 (COVID-19) global pandemic [1-3]. As the pandemic progressed, new, more transmissible but less virulent variants, like the Omicron variant, emerged and became more dominant, further reducing the mortality rate [4-8]. The World Health Organization (WHO) eventually declared that the COVID-19 pandemic no longer constitutes a public health emergency of international concern on May 2023 [9]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 24, 2024 Category: Infectious Diseases Authors: Hui Xie, Junnan Zhang, Shuang Bai, Min Lv, Juan Li, Weixin Chen, Luodan Suo, Meng Chen, Wei Zhao, Shanshan Zhou, Jian Wang, Ao Zhang, Jianxin Ma, Fengshuang Wang, Le Yan, Dongmei Li, Jiang Wu Source Type: research
Follow-up SARS-CoV-2 serological study of a health care worker cohort following COVID-19 booster vaccination
Studies have shown that Omicron breakthrough infections can occur at higher SARS-CoV-2 antibody levels compared to previous variants. Estimating the magnitude of immunological protection induced from COVID-19 ... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 24, 2024 Category: Infectious Diseases Authors: Alexander H önning, Sara Tomczyk, Julia Hermes, Marica Grossegesse, Natalie Hofmann, Janine Michel, Markus Neumann, Andreas Nitsche, Berthold Hoppe, Tim Eckmanns, Hajo Schmidt-Traub and Kristina Zappel Tags: Research Source Type: research
X (Formerly Twitter) Community Notes Addressing COVID-19 Vaccine Misinformation
This study evaluated the topics, accuracy, and credibility of X (formerly Twitter) Community Notes addressing COVID-19 vaccination. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 24, 2024 Category: General Medicine Source Type: research
Impact of SARS-CoV-2 vaccines on Covid-19 incidence and mortality in the United States
ConclusionsAssociations between complete vaccination rates and COVID-19 incidence and mortality appeared to vary with shifts in the dominant variant, perhaps due to variations in vaccine efficacy by variant or to waning vaccine immunity over time. Vaccine boosters were associated with notable protection against Omicron disease and mortality. (Source: PLoS One)
Source: PLoS One - April 24, 2024 Category: Biomedical Science Authors: Fang Fang Source Type: research
Role of the RAAS in mediating the pathophysiology of COVID-19
Pharmacol Rep. 2024 Apr 23. doi: 10.1007/s43440-024-00596-3. Online ahead of print.ABSTRACTThe renin-angiotensin-aldosterone system (RAAS) holds a position of paramount importance as enzymatic and endocrine homeostatic regulator concerning the water-electrolyte and acid-base balance. Nevertheless, its intricacy is influenced by the presence of various complementary angiotensins and their specific receptors, thereby modifying the primary RAAS actions. Angiotensin-converting enzyme 2 (ACE2) acts as a surface receptor for SARS-CoV-2, establishing an essential connection between RAAS and COVID-19 infection. Despite the recurri...
Source: Pharmacological Reports - April 23, 2024 Category: Drugs & Pharmacology Authors: Jakub Jasiczek Adrian Doroszko Tymoteusz Trocha Ma łgorzata Trocha Source Type: research
Vaksinen øling under koronapandemien blant unge med etnisk minoritetsbakgrunn i Oslo øst – en kvalitativ studie
Tidsskr Nor Laegeforen. 2024 Apr 8;144(5). doi: 10.4045/tidsskr.23.0690. Print 2024 Apr 23.ABSTRACTBACKGROUND: Few studies have been conducted on young people's attitudes to the COVID-19 vaccine during the pandemic. We wished to examine how young people with an ethnic minority background decided whether to have the COVID-19 vaccine, based on the concept of vaccine hesitancy. Vaccine hesitancy involves uncertainty with regard to vaccination, irrespective of the decision taken.MATERIAL AND METHOD: Fourteen qualitative in-depth interviews with young people aged 16-25 years with an ethnic minority background and from the east ...
Source: Tidsskrift for den Norske Laegeforening - April 23, 2024 Category: General Medicine Authors: Madhumitha Sentamilvannan Abir Al-Dekany Helena Niemi Eide Anne Kveim Lie Source Type: research
Predicting COVID-19 Vaccination Intentions to Inform Evidence-Based Messaging for Building Vaccine Confidence Among Rural Americans
CONCLUSION: COVID-19 vaccine confidence messages should address (1) positive feelings and safety perceptions, (2) vaccination's effectiveness in preventing serious COVID-19, and (3) subjective vaccination norms.PMID:38652835 | DOI:10.1177/08901171241249281 (Source: American Journal of Health Promotion : AJHP)
Source: American Journal of Health Promotion : AJHP - April 23, 2024 Category: International Medicine & Public Health Authors: Daniel Totzkay Julia Daisy Fraustino Brittany T Smith Traci Jarrett Geri A Dino Lisa M Costello Alfgeir L Kristjansson Source Type: research
CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses
Brief Bioinform. 2024 Mar 27;25(3):bbae183. doi: 10.1093/bib/bbae183.ABSTRACTCoronaviruses have threatened humans repeatedly, especially COVID-19 caused by SARS-CoV-2, which has posed a substantial threat to global public health. SARS-CoV-2 continuously evolves through random mutation, resulting in a significant decrease in the efficacy of existing vaccines and neutralizing antibody drugs. It is critical to assess immune escape caused by viral mutations and develop broad-spectrum vaccines and neutralizing antibodies targeting conserved epitopes. Thus, we constructed CovEpiAb, a comprehensive database and analysis resource ...
Source: Briefings in Bioinformatics - April 23, 2024 Category: Bioinformatics Authors: Xue Zhang JingCheng Wu Yuanyuan Luo Yilin Wang Yujie Wu Xiaobin Xu Yufang Zhang Ruiying Kong Ying Chi Yisheng Sun Shuqing Chen Qiaojun He Feng Zhu Zhan Zhou Source Type: research
COVID-19 Vaccine Intention Among Iranian Health Workers: Application of the HBM Model
Soc Work Public Health. 2024 Apr 23:1-10. doi: 10.1080/19371918.2024.2325553. Online ahead of print.ABSTRACTThe study aimed to determine the application of the health belief model (HBM) in the acceptance of COVID-19 vaccination among health workers in 2021. The cross-sectional study was conducted on 3600 health workers from February to March 2021. Data was collected using a researcher-made questionnaire that included the intention to receive vaccines based on the health belief model constructs. Data were analyzed using descriptive statistics indicators, Chi-square, ANOVA test, and logistic regression model at a 95% confide...
Source: Social Work in Public Health - April 23, 2024 Category: International Medicine & Public Health Authors: Azam Maleki Seyed Mohsen Zahraei Sousan Mahmoudi Mohammad Mehdi Gouya Koorosh Kamali Zarrintaj Hoseinzade Mahya Farsadeghi Khadijeh Hajimiri Zahra Heidari Soraya Mohamadi Zohreh Bigdeli Alireza Shoghli Source Type: research
