Analysis of causal relations between vaccine hesitancy for COVID-19 vaccines and ideological orientations in Brazil
This article presents a causal inference analysis of vaccine hesitancy for Coronavirus disease 2019 (COVID-19) vaccines based on socio-demographic data obtained via questionnaires applied to a sample of the Brazilian population. This data includes the respondents' political preferences, age group, education, salary range, country region, sex, believing fake news, vaccine confidence, and intention to get the COVID-19 vaccine. The research created a causal graph using these variables, seeking to answer questions about the probability of people getting vaccinated. The results of this research corroborate findings observed in ...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Eanes Torres Pereira Sylvia Iasulaitis Bruno Cardoso Greco Source Type: research
Avoidable COVID-19-related deaths and hospitalizations in Brazil, 2020-2023
CONCLUSIONS: PLPE reduction in 2023 was likely caused by low vaccine uptake. The disease burden could have been much lower had the vaccination started earlier and had the vaccine uptake not dropped so sharply in 2023.PMID:38631953 | DOI:10.1016/j.vaccine.2024.04.041 (Source: Vaccine)
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Emil Kupek Source Type: research
Overview of U.S. COVID-19 vaccine safety surveillance systems
This report describes the U.S. government's COVID-19 vaccine safety monitoring systems and programs used by the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the Department of Defense, the Department of Veterans Affairs, and the Indian Health Service. Using the adverse event of myocarditis following mRNA COVID-19 vaccination as a model, we demonstrate how the multiple, complementary monitoring systems worked to rapidly detect, assess, and verify a vaccine safety signal. In addition, longer-term follow-up was conducted to evaluate the recovery status of myocarditis cases following vaccin...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Julianne Gee Tom T Shimabukuro John R Su David Shay Margaret Ryan Sridhar V Basavaraju Karen R Broder Matthew Clark C Buddy Creech Francesca Cunningham Kristin Goddard Harrison Guy Kathryn M Edwards Richard Forshee Tanya Hamburger Anne M Hause Nicola P Kl Source Type: research
COVID-19 vaccination communication: Effects of vaccine conspiracy beliefs and message framing among black and white participants
CONCLUSION: It is crucial for health officials to work to find effective media message strategies to combat COVID-19 vaccine conspiracy theories and misinformation. Furthermore, this study supports the significance of health organizations' ongoing efforts to tailor public health messaging to specific racial groups, as evidenced by considerable variations in perceptions among Black and White Americans.PMID:38631951 | DOI:10.1016/j.vaccine.2024.04.001 (Source: Vaccine)
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Namyeon Lee Yoorim Hong Ciera E Kirkpatrick Sisi Hu Sungkyoung Lee Amanda Hinnant Source Type: research
Understanding the views of adult migrants around catch-up vaccination for missed routine immunisations to define strategies to improve coverage: A UK in-depth interview study
CONCLUSIONS: The major barrier to adult catch-up vaccination for missed routine immunisations and doses in migrant communities in the UK is the limited opportunities, recommendations or tailored vaccination information presented to migrants by health services. This could be improved with financial incentives for provision of catch-up vaccination in UK primary care, alongside training of healthcare professionals to support catch-up immunisation and raise awareness of existing guidelines. It will also be essential to address root causes of mistrust around vaccination, where it exists among migrants, by working closely with c...
Source: Vaccine - April 17, 2024 Category: Allergy & Immunology Authors: Anna Deal Alison F Crawshaw Maha Salloum Sally E Hayward Jessica Carter Felicity Knights Farah Seedat Oumnia Bouaddi Nuria Sanchez-Clemente Laura Muzinga Lutumba Lusau Mimi Kitoko Sarah Nkembi Caroline Hickey Sandra Mounier-Jack Azeem Majeed Sally Hargrea Source Type: research
SARS-CoV-2 Infection, Hospitalization, and Associated Factors Among People Living With HIV in Southeastern China From December 2022 to February 2023: Cross-Sectional Survey
CONCLUSIONS: After the ease of prevention and control measures in China, we observed a high SARS-CoV-2 infection rate but a low hospitalization rate. General risk factors, such as higher age and vaccination status, and HIV-related parameters, such as the latest CD4 cell count and HIV viral load, were associated with SARS-CoV-2 infection and hospitalization. A booster vaccination campaign for booster doses should be considered among people living with HIV in confronting possible COVID-19 epidemic emergencies in the near future.PMID:38630534 | DOI:10.2196/51449 (Source: Cancer Control)
Source: Cancer Control - April 17, 2024 Category: Cancer & Oncology Authors: Wei Cheng Yun Xu Haibo Jiang Jun Li Zhigang Hou Haibin Meng Wei Wang Chengliang Chai Jianmin Jiang Source Type: research
Incidence of SARS-CoV-2 Seropositivity in Pediatric Healthcare Workers Prior to Widespread Vaccination: A Five-month Longitudinal Cohort Study
Understanding the prevalence and incidence of SARS-CoV-2 infection among frontline healthcare workers is important to inform health policy and strategy. In the early stages of the COVID-19 pandemic, children were thought to be at low risk for infection, suggesting minimal risk of work-acquired SARS-CoV-2 infection in pediatric healthcare workers (pHCWs). This is due to early hypotheses that children were not affected by and did not spread SARS-CoV-2 to the degree that was seen among adult patients and their caregivers [1]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 17, 2024 Category: Infectious Diseases Authors: Mark Griffiths, Dunia Hatabah, Patrick Sullivan, Grace Mantus, Travis Sanchez, Maria Zlotorzynska, Stacy Heilman, Andres Camacho-Gonzalez, Deborah Leake, Rawan Korman, Mimi Le, Mehul Suthara, Jens Wrammert, Miriam B. Vos, Claudia R. Morris Source Type: research
IJERPH, Vol. 21, Pages 491: Optimizing the Selection of Mass Vaccination Sites: Access and Equity Consideration
all
In the early phases of the COVID-19 pandemic, vaccine accessibility was limited, impacting large metropolitan areas such as Los Angeles County, which has over 10 million residents but only nine initial vaccination sites, which resulted in people experiencing long travel times to get vaccinated. We developed a mixed-integer linear model to optimize site selection, considering equitable access for vulnerable populations. Analyzing 277 zip codes between December 2020 and May 2021, our model incorporated factors such as car ownership, ethnic group disease vulnerability, and the Healthy Places Index, alongside travel ti...
Source: International Journal of Environmental Research and Public Health - April 17, 2024 Category: Environmental Health Authors: Basim Aljohani Randolph Hall Tags: Article Source Type: research
Translation and trans-cultural adaptation to the Malay version of the COVID-19 vaccine hesitancy questionnaire among healthcare workers in Malaysia
ConclusionsThe questionnaire was valid and reliable for use in the Malay language. (Source: PLoS One)
Source: PLoS One - April 17, 2024 Category: Biomedical Science Authors: Siti Nur Aisyah Zaid Source Type: research
COVID-19 vaccine acceptance in the general population and under-resourced communities from high-income countries: realist review
Conclusion
Our review emphasises the importance of realist reviews for assessing vaccine acceptance. Limited real-world evidence about vaccine uptake among under-resourced communities in high-income countries is a call to context-specific actions and reporting. (Source: BMJ Open)
Source: BMJ Open - April 17, 2024 Category: General Medicine Authors: Gonzalez-Jaramillo, N., Abbühl, D., Roa-Diaz, Z. M., Kobler-Betancourt, C., Frahsa, A. Tags: Open access, Public health Source Type: research
Potential impact of annual vaccination with reformulated COVID-19 vaccines: Lessons from the US COVID-19 scenario modeling hub
ConclusionsCOVID-19 is projected to be a significant public health threat over the coming 2 years. Broad vaccination has the potential to substantially reduce the burden of this disease, saving tens of thousands of lives each year. (Source: PLoS Medicine)
Source: PLoS Medicine - April 17, 2024 Category: Internal Medicine Authors: Sung-mok Jung Source Type: research
Plans to expand African vaccine production face steep hurdles
In March 2022, when the pandemic was still raging, the messenger RNA (mRNA) company Moderna announced it would build a $500 million plant in Kenya to manufacture half a billion doses of its COVID-19 vaccine annually. “
This is major
,” Kenyan President William Ruto said at the time. The plant would help reduce Africa’s dependence on vaccines produced elsewhere, Ruto said—a situation that had turned disastrous during the pandemic—and bring economic benefits as well.
But Moderna may never break ground on the Kenya factory. On 11 April, the company said it had
“paused its efforts”
becau...
Source: Science of Aging Knowledge Environment - April 16, 2024 Category: Geriatrics Source Type: research
Recent advances in immunotherapies against infectious diseases
Immunother Adv. 2020 Nov 25;1(1):ltaa007. doi: 10.1093/immadv/ltaa007. eCollection 2021 Jan.ABSTRACTImmunotherapies are disease management strategies that target or manipulate components of the immune system. Infectious diseases pose a significant threat to human health as evidenced by countries continuing to grapple with several emerging and re-emerging diseases, the most recent global health threat being the SARS-CoV2 pandemic. As such, various immunotherapeutic approaches are increasingly being investigated as alternative therapies for infectious diseases, resulting in significant advances towards the uncovering of path...
Source: Cancer Control - April 16, 2024 Category: Cancer & Oncology Authors: Dharanidharan Ramamurthy Trishana Nundalall Sanele Cingo Neelakshi Mungra Maryam Karaan Krupa Naran Stefan Barth Source Type: research
Review of COVID-19 Therapeutics by Mechanism: From Discovery to Approval
J Korean Med Sci. 2024 Apr 15;39(14):e134. doi: 10.3346/jkms.2024.39.e134.ABSTRACTThe global research and pharmaceutical community rapidly mobilized to develop treatments for coronavirus disease 2019 (COVID-19). Existing treatments have been repurposed and new drugs have emerged. Here we summarize mechanisms and clinical trials of COVID-19 therapeutics approved or in development. Two reviewers, working independently, reviewed published data for approved COVID-19 vaccines and drugs, as well as developmental pipelines, using databases from the following organizations: United States Food and Drug Administration (US-FDA), Euro...
Source: J Korean Med Sci - April 16, 2024 Category: General Medicine Authors: Hee Sun Choi A Young Choi Jeffrey B Kopp Cheryl A Winkler Sung Kweon Cho Source Type: research
Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination
CONCLUSION: Receipt of an mRNA COVID-19 vaccine during pregnancy was not associated with an increased risk of adverse pregnancy outcomes; this information will be helpful for patients and clinicians when considering COVID-19 vaccination in pregnancy.PMID:38626447 | DOI:10.1097/AOG.0000000000005583 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - April 16, 2024 Category: OBGYN Authors: Kimberly K Vesco Anna E Denoble Heather S Lipkind Elyse O Kharbanda Malini B DeSilva Matthew F Daley Darios Getahun Ousseny Zerbo Allison L Naleway Lisa Jackson Joshua T B Williams Thomas G Boyce Candace C Fuller Eric S Weintraub Gabriela Vazquez-Benitez Source Type: research
