Risk factors for severe COVID-19 infection and the impact of COVID-19 infection on disease progression among patients with AAV
AbstractTo identify risk factors for COVID-19 infection and investigate the impact of COVID-19 infection on chronic kidney disease (CKD) progression and vasculitis flare in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). This cohort study retrospectively analyzed the prevalence and severity of COVID-19 infection in 276 patients with AAV who were followed up. Logistic regression was employed to estimate the risk of COVID-19 infection as well as CKD progression and vasculitis flare upon COVID-19 infection. During the 6-month observation period, 213 (77.2%) of 276 patients were diagnosed ...
Source: Clinical and Experimental Medicine - April 29, 2024 Category: Research Source Type: research
Collective good and individual choice: Perceptions on COVID-19 vaccine mandate among COVID-19 vaccinated individuals
CONCLUSION: Support for a COVID-19 vaccination mandate is controversial even among vaccinated people. Identifying and understanding cultural and contextual factors that underlie differences in attitudes and beliefs about COVID-19 vaccination mandates is essential to advance dialogue and inform educational health campaigns to increase COVID-19 vaccination rates.PMID:38679513 | DOI:10.1016/j.vaccine.2024.04.052 (Source: Vaccine)
Source: Vaccine - April 28, 2024 Category: Allergy & Immunology Authors: Kaivalya Gudooru Kimberly Nguyen Kathy Le Vyas Sarabu Meredith Hosek Anna Phan Michelle Garza Bertha E Flores Armida Flores Amelie Ramirez Luz M Garcini Source Type: research
Association between Covishield vaccine and menstrual disturbance. Findings from a cross-sectional study among participants of Zero TB cohort in India
CONCLUSION: Menstrual problems were reported by Covishield vaccinees, but they were minor and reversible within three months and do not constitute a ground for vaccine hesitancy. Studies designed to assess causal link taking care to avoid selection bias or confounding are needed.PMID:38679512 | DOI:10.1016/j.vaccine.2024.04.063 (Source: Vaccine)
Source: Vaccine - April 28, 2024 Category: Allergy & Immunology Authors: Kunchok Dorjee Tenzin Namdon Sonam Topgyal Ugen Gyatso Tenzin Tsundue Tashi Dolma Vipan Kumar Dekyi Lhadon Tenzin Yangkyi Tenzin Khachoe Sangyal Dorjee R C Sadoff David Peters Amita Gupta Zorba Paster Richard E Chaisson Dawa Phunkyi Tsetan D Sadutshang Source Type: research
Analysis of beliefs about COVID-19 vaccines among the adult Hungarian population from a health communication perspective
Orv Hetil. 2024 Apr 28;165(17):664-671. doi: 10.1556/650.2024.33024. Print 2024 Apr 28.ABSTRACTBevezetés: A magyar lakosság az európai uniós átlaghoz képest kisebb arányban vette fel a COVID–19 elleni védőoltást. A hazai deprivált települések lakosainak körében az oltás felvétele pedig 38,2%-kal volt kisebb arányú az országos átlaghoz képest. Az oltási program egyik legfőbb akadálya a lakossági bizalmatlanság volt. Célkitűzés: A COVID–19-védőoltással kapcsolatos lakossági hiedelmek feltárása és a járvánnyal kapcsolatos tájékozódásra használt tömegmédiumok azonosítása. Mó...
Source: Orvosi Hetilap - April 28, 2024 Category: General Medicine Authors: Csilla Zsigmond J ózsef Vitrai Zolt án Brys Source Type: research
Collective good and individual choice: Perceptions on COVID-19 vaccine mandate among COVID-19 vaccinated individuals
CONCLUSION: Support for a COVID-19 vaccination mandate is controversial even among vaccinated people. Identifying and understanding cultural and contextual factors that underlie differences in attitudes and beliefs about COVID-19 vaccination mandates is essential to advance dialogue and inform educational health campaigns to increase COVID-19 vaccination rates.PMID:38679513 | DOI:10.1016/j.vaccine.2024.04.052 (Source: Vaccine)
Source: Vaccine - April 28, 2024 Category: Allergy & Immunology Authors: Kaivalya Gudooru Kimberly Nguyen Kathy Le Vyas Sarabu Meredith Hosek Anna Phan Michelle Garza Bertha E Flores Armida Flores Amelie Ramirez Luz M Garcini Source Type: research
Association between Covishield vaccine and menstrual disturbance. Findings from a cross-sectional study among participants of Zero TB cohort in India
CONCLUSION: Menstrual problems were reported by Covishield vaccinees, but they were minor and reversible within three months and do not constitute a ground for vaccine hesitancy. Studies designed to assess causal link taking care to avoid selection bias or confounding are needed.PMID:38679512 | DOI:10.1016/j.vaccine.2024.04.063 (Source: Vaccine)
Source: Vaccine - April 28, 2024 Category: Allergy & Immunology Authors: Kunchok Dorjee Tenzin Namdon Sonam Topgyal Ugen Gyatso Tenzin Tsundue Tashi Dolma Vipan Kumar Dekyi Lhadon Tenzin Yangkyi Tenzin Khachoe Sangyal Dorjee R C Sadoff David Peters Amita Gupta Zorba Paster Richard E Chaisson Dawa Phunkyi Tsetan D Sadutshang Source Type: research
Analysis of beliefs about COVID-19 vaccines among the adult Hungarian population from a health communication perspective
Orv Hetil. 2024 Apr 28;165(17):664-671. doi: 10.1556/650.2024.33024. Print 2024 Apr 28.ABSTRACTBevezetés: A magyar lakosság az európai uniós átlaghoz képest kisebb arányban vette fel a COVID–19 elleni védőoltást. A hazai deprivált települések lakosainak körében az oltás felvétele pedig 38,2%-kal volt kisebb arányú az országos átlaghoz képest. Az oltási program egyik legfőbb akadálya a lakossági bizalmatlanság volt. Célkitűzés: A COVID–19-védőoltással kapcsolatos lakossági hiedelmek feltárása és a járvánnyal kapcsolatos tájékozódásra használt tömegmédiumok azonosítása. Mó...
Source: Orvosi Hetilap - April 28, 2024 Category: General Medicine Authors: Csilla Zsigmond J ózsef Vitrai Zolt án Brys Source Type: research
Viruses, Vol. 16, Pages 697: SARS-CoV-2 Omicron: Viral Evolution, Immune Evasion, and Alternative Durable Therapeutic Strategies
er
Tong-Ming Fu
Since the SARS-CoV-2 Omicron virus has gained dominance worldwide, its continual evolution with unpredictable mutations and patterns has revoked all authorized immunotherapeutics. Rapid viral evolution has also necessitated several rounds of vaccine updates in order to provide adequate immune protection. It remains imperative to understand how Omicron evolves into different subvariants and causes immune escape as this could help reevaluate the current intervention strategies mostly implemented in the clinics as emergency measures to counter the pandemic and, importantly, develop new solutions. Here, w...
Source: Viruses - April 28, 2024 Category: Virology Authors: Hailong Guo Sha Ha Jason W. Botten Kai Xu Ningyan Zhang Zhiqiang An William R. Strohl John W. Shiver Tong-Ming Fu Tags: Review Source Type: research
Risk factors for SARS-CoV-2 infection at a UK electricity-generating company: a test-negative design case-control study
Conclusions
In general, infection risk was not associated with job category. Vulnerable individuals were at slightly lower risk, tests during outages were higher risk, vaccination showed no evidence of an effect on testing positive, and site COVID-19 risk rating did not show an ordered trend in positivity rates. (Source: Occupational and Environmental Medicine)
Source: Occupational and Environmental Medicine - April 28, 2024 Category: Occupational Health Authors: Rutter, C. E., van Tongeren, M., Fletcher, T., Rhodes, S., Chen, Y., Hall, I., Warren, N., Pearce, N. Tags: Open access, COVID-19 Workplace Source Type: research
How could our genetics impact COVID-19 vaccine response?
Expert Rev Clin Immunol. 2024 Apr 27:1-13. doi: 10.1080/1744666X.2024.2346584. Online ahead of print.ABSTRACTINTRODUCTION: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has posed unprecedented global health challenges since its emergence in December 2019. The rapid availability of vaccines has been estimated to save millions of lives, but there is variation in how individuals respond to vaccines, influencing their effectiveness at an individual, and population level.AREAS COVERED: This review focuses on human genetic factors influencing the immune response and effectiveness of vaccines, highlighting the importance...
Source: Expert Review of Clinical Immunology - April 27, 2024 Category: Allergy & Immunology Authors: Keyi Zheng Amanda Y Chong Alexander J Mentzer Source Type: research
SARS-CoV-2 evolution has increased resistance to monoclonal antibodies and first-generation COVID-19 vaccines: Is there a future therapeutic role for soluble ACE2 receptors for COVID-19?
Antiviral Res. 2024 Apr 25:105894. doi: 10.1016/j.antiviral.2024.105894. Online ahead of print.ABSTRACTCOVID-19 has caused calamitous health, economic and societal consequences. Although several COVID-19 vaccines have received full authorization for use, global deployment has faced political, financial and logistical challenges. The efficacy of first-generation COVID-19 vaccines is waning and breakthrough infections are allowing ongoing transmission and evolution of SARS-CoV-2. Furthermore, COVID-19 vaccine efficacy relies on a functional immune system. Despite receiving three primary doses and three or more heterologous b...
Source: Antiviral Research - April 27, 2024 Category: Virology Authors: Rohan Ameratunga Anthony Jordan Klaus Lehnert Euphemia Leung Emily R Mears Russell Snell Richard Steele See-Tarn Woon Source Type: research
The role of religion and COVID-19 vaccine uptake in England
CONCLUSION: This research indicates a potential influence of religious affiliation on vaccine uptake, highlighting the need for more carefully-tailored public health programmes. Recognizing the diverse associations of different religious affiliations on health behaviour is important for shaping future vaccination campaigns and policy interventions. Engaging with religious communities and leaders may be one method through which to deal with vaccine hesitancy and improve public health.PMID:38677793 | DOI:10.1016/j.vaccine.2024.04.006 (Source: Vaccine)
Source: Vaccine - April 27, 2024 Category: Allergy & Immunology Authors: Martin Ejnar Hansen Steven David Pickering Source Type: research
How could our genetics impact COVID-19 vaccine response?
Expert Rev Clin Immunol. 2024 Apr 27:1-13. doi: 10.1080/1744666X.2024.2346584. Online ahead of print.ABSTRACTINTRODUCTION: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has posed unprecedented global health challenges since its emergence in December 2019. The rapid availability of vaccines has been estimated to save millions of lives, but there is variation in how individuals respond to vaccines, influencing their effectiveness at an individual, and population level.AREAS COVERED: This review focuses on human genetic factors influencing the immune response and effectiveness of vaccines, highlighting the importance...
Source: Expert Review of Clinical Immunology - April 27, 2024 Category: Allergy & Immunology Authors: Keyi Zheng Amanda Y Chong Alexander J Mentzer Source Type: research
Stability analysis and numerical evaluations of a COVID-19 model with vaccination
A novel (nonlinear) mathematical model for the transmission of Coronavirus 19 (COVID-19) with eight compartments and considering the impact of vaccination is examined in this manuscript. The qualitative behavi... (Source: BMC Medical Research Methodology)
Source: BMC Medical Research Methodology - April 27, 2024 Category: Research Authors: Mohammad Izadi and Tayebeh Waezizadeh Tags: Research Source Type: research
Evaluating Humoral Immunity Elicited by XBB.1.5 Monovalent COVID-19 Vaccine
We report boosting of IgG (2.1×), IgA (1.5×), and total IgG/A/M (1.7×) targeting the spike receptor-binding domain and neutralizing titers against WA1 (2.2×), XBB.1.5 (7.4×), EG.5.1 (10.5×), and JN.1 (4.7×) variants.PMID:38669121 | DOI:10.3201/eid3006.240051 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Xammy Huu Nguyenla Timothy A Bates Mila Trank-Greene Mastura Wahedi Fikadu G Tafesse Marcel Curlin Source Type: research
