Viruses, Vol. 16, Pages 685: Impact of Prior COVID-19 Immunization and/or Prior Infection on Immune Responses and Clinical Outcomes
oglou Cellular and humoral immunity exhibit dynamic adaptation to the mutating SARS-CoV-2 virus. It is noteworthy that immune responses differ significantly, influenced by whether a patient has received vaccination or whether there is co-occurrence of naturally acquired and vaccine-induced immunity, known as hybrid immunity. The different immune reactions, conditional on vaccination status and the viral variant involved, bear implications for inflammatory responses, patient outcomes, pathogen transmission rates, and lingering post-COVID conditions. Considering these developments, we have performed a review of recently ...
Source: Viruses - April 26, 2024 Category: Virology Authors: Achilleas Livieratos Charalambos Gogos Karolina Akinosoglou Tags: Review Source Type: research

Effectiveness of BNT162b2 COVID-19 primary series vaccination in children aged 5 –17 years in the United States: a cohort study
This study ’s objective was to estimate the effectiveness of rece... (Source: BMC Pediatrics)
Source: BMC Pediatrics - April 26, 2024 Category: Pediatrics Authors: Rachel P. Ogilvie, J. Bradley Layton, Patricia C. Lloyd, Yixin Jiao, Djeneba Audrey Djibo, Hui Lee Wong, Joann F. Gruber, Ron Parambi, Jie Deng, Michael Miller, Jennifer Song, Lisa B. Weatherby, Lauren Peetluk, An-Chi Lo, Kathryn Matuska, Michael Wernecke Tags: Research Source Type: research

The impact of quality-adjusted life years on evaluating COVID-19 mitigation strategies: lessons from age-specific vaccination roll-out and variants of concern in Belgium (2020-2022)
When formulating and evaluating COVID-19 vaccination strategies, an emphasis has been placed on preventing severe disease that overburdens healthcare systems and leads to mortality. However, more conventional ... (Source: BMC Public Health)
Source: BMC Public Health - April 26, 2024 Category: Consumer Health News Authors: Lander Willem, Steven Abrams, Nicolas Franco, Pietro Coletti, Pieter J. K. Libin, James Wambua, Simon Couvreur, Emmanuel Andr é, Tom Wenseleers, Zhuxin Mao, Andrea Torneri, Christel Faes, Philippe Beutels and Niel Hens Tags: Research Source Type: research

Lessons we learned during the past four challenging years in the COVID-19 era: pharmacotherapy, long COVID complications, and vaccine development
About four years have passed since the detection of the first cases of COVID-19 in China. During this lethal pandemic, millions of people have lost their lives around the world. Since the first waves of COVID-... (Source: Virology Journal)
Source: Virology Journal - April 26, 2024 Category: Virology Authors: Parisa Ghasemiyeh and Soliman Mohammadi-Samani Tags: Review Source Type: research

Promoting COVID-19 Vaccine Confidence and Access among Youth Experiencing Homelessness: Community-Engaged Public Health Practice
CONCLUSIONS: This community-engaged project highlighted the value of cross-sector partnership and consistent youth engagement in addressing vaccine confidence among YEH.PMID:38661829 (Source: Progress in Community Health Partnerships)
Source: Progress in Community Health Partnerships - April 25, 2024 Category: International Medicine & Public Health Authors: Ingie Osman Renee Sieving Lauren Vasilakos Katie Pierson Asha Elgonda Trenton Bartlett Janna R Gewirtz O'Brien Source Type: research

Vaccine Attitudes and Uptake Among Latino Residents of a Former COVID-19 Hotspot
This study uses spatial, survey, and qualitative data to understand attitudes towards vaccine uptake among PWC Latinos. A quantitative analysis (n=266) estimates the association for vaccine acceptance among Latinos. Next, qualitative interviews with Latinos (n=37) examine vaccine attitudes. Finally, a spatial analysis identifies clusters of social vulnerability and low vaccine uptake in PWC and adjacent counties. Our findings show that a substantial proportion of PWC Latinos had low vaccination rates as of December 2022, two years after the vaccine's release. Side effects and safety and approval concerns were cited in both...
Source: Journal of Health Care for the Poor and Underserved - April 25, 2024 Category: International Medicine & Public Health Authors: Carol Cleaveland Taylor Anderson Kimberly McNally Amira A Roess Source Type: research

Use of an Additional Updated 2023-2024 COVID-19 Vaccine Dose for Adults Aged ≥65 Years: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024
MMWR Morb Mortal Wkly Rep. 2024 Apr 25;73(16):377-381. doi: 10.15585/mmwr.mm7316a4.ABSTRACTCOVID-19 remains an important public health threat, despite overall decreases in COVID-19-related severe disease since the start of the COVID-19 pandemic. COVID-19-associated hospitalization rates remain higher among adults aged ≥65 years relative to rates in younger adults, adolescents, and children; during October 2023-January 2024, 67% of all COVID-19-associated hospitalizations were among persons aged ≥65 years. On September 12, 2023, CDC's Advisory Committee on Immunization Practices (ACIP) recommended updated (2023-2024 For...
Source: MMWR Morb Mortal Wkl... - April 25, 2024 Category: Epidemiology Authors: Lakshmi Panagiotakopoulos Monica Godfrey Danielle L Moulia Ruth Link-Gelles Christopher A Taylor Kevin Chatham-Stephens Oliver Brooks Matthew F Daley Katherine E Fleming-Dutra Megan Wallace Source Type: research

Physical Activity at Different Life Stages and Its Consequence on the Initial Immunization and Inflammatory Response Against COVID-19
CONCLUSION: Our results suggest that adults that accumulated at least 150 minutes of MVPA per week or practiced PA during adolescence developed an improved immune and inflammatory response against COVID-19 vaccination.PMID:38663845 | DOI:10.1123/jpah.2023-0370 (Source: Health Physics)
Source: Health Physics - April 25, 2024 Category: Physics Authors: Priscila Almeida Queiroz Rossi Regis Gomes Teresa Cristina do Nascimento Salazar Esmeralda Maria Lustosa Barros Silvia Vasconcelos Adalberto Socorro da Silva Ester Miranda Pereira Vitoria Braga Melo Marcela Helena Gambin Fonseca Clarissa Romero Teixeira G Source Type: research

Historical Lessons on Vaccine Hesitancy: Smallpox, Polio, and Measles, and Implications for COVID-19
This study examines the history of US vaccination efforts against smallpox, polio, and measles, highlighting persistent drivers of vaccine hesitancy as well as factors that helped overcome it. The research reveals that logistical barriers, negative portrayals in the media, and fears about safety stymied inoculation efforts as early as the 18th century and continue to do so. However, vaccine hesitancy has been markedly diminished when trusted community leaders have guided efforts, when ordinary citizens have felt personally invested in the success of the vaccine, and when vaccination efforts have been tied to broader projec...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: J J Eddy H A Smith J E Abrams Source Type: research

Herd Immunity: History, Concepts, and Ethical Rationale
This article provides a conceptual framework tailored to uncover the ethical rationale behind such strategies. Clarity on this issue is important in order to facilitate the terms of the political debate when tackling future health emergencies.PMID:38662008 | DOI:10.1353/pbm.2023.0003 (Source: Perspectives in Biology and Medicine)
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: Davide Vecchi Giorgio Airoldi Source Type: research

On Antiscience and Antisemitism
This article provides both historical and recent perspectives on the links between antiscience and antisemitism, together with the author's personal experience as a Jewish vaccine scientist targeted by both dark forces. New approaches to uncoupling antisemitism from antiscience, while combating both, are essential for saving lives and preserving democratic values.PMID:38661936 | DOI:10.1353/pbm.2023.a902035 (Source: Perspectives in Biology and Medicine)
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: Peter Hotez Source Type: research

Physical Activity at Different Life Stages and Its Consequence on the Initial Immunization and Inflammatory Response Against COVID-19
CONCLUSION: Our results suggest that adults that accumulated at least 150 minutes of MVPA per week or practiced PA during adolescence developed an improved immune and inflammatory response against COVID-19 vaccination.PMID:38663845 | DOI:10.1123/jpah.2023-0370 (Source: Journal of Physical Activity and Health)
Source: Journal of Physical Activity and Health - April 25, 2024 Category: Sports Medicine Authors: Priscila Almeida Queiroz Rossi Regis Gomes Teresa Cristina do Nascimento Salazar Esmeralda Maria Lustosa Barros Silvia Vasconcelos Adalberto Socorro da Silva Ester Miranda Pereira Vitoria Braga Melo Marcela Helena Gambin Fonseca Clarissa Romero Teixeira G Source Type: research

Low vaccine coverage and varicella outbreaks in Brazil - 2019-2022
Vaccine. 2024 Apr 24:S0264-410X(24)00435-3. doi: 10.1016/j.vaccine.2024.04.021. Online ahead of print.ABSTRACTThe persistence of varicella outbreaks in Brazil has underscored the high concern with the low vaccine coverage in the last 4 years. Using publicly available data from the Brazilian Health System (SUS), this study analyzed varicella vaccine coverage and incidence trends from 2019 to 2022 in Brazilian States. Vaccine coverage decreased nationally in 2020, possibly influenced by the COVID-19 pandemic's initial phase. In Bahia State, we have the persistence of varicella with an incidence rate of 3.0 cases per 100,000 ...
Source: Vaccine - April 25, 2024 Category: Allergy & Immunology Authors: Dennis Minoru Fujita Luiz Henrique da Silva Nali Rafael Rodrigues da Costa Heitor Franco de Andrade J únior Expedito Jos é de Albuquerque Luna Source Type: research

Severe acute myositis and myocarditis on initiation of 6-weekly pembrolizumab post-COVID-19 mRNA vaccination
In conclusion, we report a series of unusually severe myositis and myocarditis following PD-1 blockade and the COVID-19 mRNA vaccination.PMID:38663935 | DOI:10.1136/jitc-2023-008151 (Source: Cancer Control)
Source: Cancer Control - April 25, 2024 Category: Cancer & Oncology Authors: Robert A Watson Weiyu Ye Chelsea A Taylor Elsita Jungkurth Rosalin Cooper Orion Tong Tim James Brian Shine Monika Hofer Damian Jenkins Robert Pell Eleni Ieremia Stephanie Jones David Maldonado-Perez Ian S D Roberts Nicholas Coupe Mark R Middleton Miranda Source Type: research

Promoting COVID-19 Vaccine Confidence and Access among Youth Experiencing Homelessness: Community-Engaged Public Health Practice
CONCLUSIONS: This community-engaged project highlighted the value of cross-sector partnership and consistent youth engagement in addressing vaccine confidence among YEH.PMID:38661829 (Source: Progress in Community Health Partnerships)
Source: Progress in Community Health Partnerships - April 25, 2024 Category: International Medicine & Public Health Authors: Ingie Osman Renee Sieving Lauren Vasilakos Katie Pierson Asha Elgonda Trenton Bartlett Janna R Gewirtz O'Brien Source Type: research